Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SNCB TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12867415
ABL1 CDC27 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
BUB1B CDK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11285280 10679238
CDC20 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12196507 9628895
TP53 CDC20 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19273532 17873905
E2F4 CDC20 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15574595 18319725
TP53 CDC20 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19273532
CDK1 MAD2L1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11285280 10679238
CDK1 MAPK6 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 18235225 20236090
FXR1 CDR2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
CENPJ CEP135 â—¼   COLOCALIZATION 2.0 0.8 intact 20531387 7994481
FXR1 CEP89 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
E2F4 CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12909625
FXR1 DCTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
NDC80 DCTN1 â—¼   COLOCALIZATION 2.0 0.8 intact 8057081 20664522
LRRK2 E2F4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
TP53 E2F4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15574328 24096481
E2F4 MAD2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
E2F4 PRC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
E2F4 NDC80 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
E2F4 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15580623 18319725
E2F4 NDC80 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18319725 16135806
FXR1 TACC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
FXR1 MAD1L1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
NINL MAD1L1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
TP53 MAD1L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12876282
MAD1L1 MAD2L1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
TP53 MAD1L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18431400
TP53 PRC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15531928
TACC2 TTK â—¼   COLOCALIZATION 2.0 0.8 intact 15304323 5217142
TTK TACC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15304323 5217142
TUBB TTK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15304323 5217142
CCNB1 CDC27 â—¼   PHYSICAL_INTERACTION 806.0 0.8 STRING 36370105
CADH1 FGFR1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 27371729 25241761 11401320
UBE2C CDC20 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 17443186 29735662 34382737 32152539 19820702
TP53 HSPA9 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5219502 17184779
CDC27 UBE2C â—¼   PHYSICAL_INTERACTION 816.0 0.81 STRING 36370105
CADH1 TTK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25468996 20729194
I13R2 TTK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VMAT1 TTK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
S39A9 TTK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
APJ TTK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
C5ARL TTK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
C5ARL NCUG1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
F174A TTK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MAS TTK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NCUG1 TTK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GRPR TTK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ACM4 TTK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GTR12 TTK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NUF2 CASC5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
CDC16 ESPL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MOV10 CDC20 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22658674 29395067
CDK2 CDK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 21319273
CDK2 E2F4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25852190 33961781
CEP63 NDC80 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 34079125
LRRK2 KIF2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
KIF2C KIF2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
LPAR4 TTK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NPY2R TTK â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SPAG5 PCM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26297806 34079125
NDC80 SPC24 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CDC20 CDK1 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
ABL1 HSP90AA1 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
TTK CDC27 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 20729194 12686615 22045814
PCM1 CEP63 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31413325 26638075 34079125
NIN DCTN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28718761 26638075 34079125
NINL DCTN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28718761 27173435 26485645
DCTN1 PRC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31586073 26638075 34079125
NIN NDC80 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28718761 34079125
NIN PCM1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30217970 26638075 28718761 34079125
CDC16 UBE2C â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CDK1 CDC20 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28514442 26912231 10799291
BUB1B FZR1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
CDC20 FZR1 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
CCNB1 FXR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 29395067 26496610
CDK2 TP53 â—¼   PHOSPHORYLATION ✅ + 0.86 0.86 Signor 24173284
PCM1 HMMR â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26638075 34079125
NDC80 NUF2 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CASC5 NDC80 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
MAD2L1 BUB1B â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 21772247 8284719
CASC5 SPC24 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
ESPL1 CCNB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 30674583 24781523 25750436 17604273
CDC20 CCNB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23239745 20383333 25161877 31230944 20080579 25306923 10799291 20733055 25482201 23091007 32152539 19820702 25825779 22014574 12956947 24151075 23007861 17360335 22193957 19826003 26912231 14701726 23791783 27522463 25246557 31455778 18471975 23288039 23979597 11562349 26387737 33082289 11804586 25505175
CDK2 CDC20 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 23455922 26811472 25852190 28514442
PCM1 CENPJ â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26496610 26638075 34079125
CHEK2 TP53 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HSPA9 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CEP152 CEP63 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
NUF2 SPC24 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
CDC16 BUB1B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 20360068 11030144 24151075 32707033 10477750
SPC24 CASC5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 24981860 26496610 23334297 26186194 28514442
PCM1 NDC80 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 27107012 26638075 34079125
CADH1 CDC27 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12956947 16479161 22539978 20951947 9734353 20802534 23160376 24811168 20686030
CDC20 BUB1B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25502805 11702782 21407176 23643811 23239745 29973720 23007648 22566641 27939943 12196507 18591651 19098431 24464857 25383541 26960431 23443559 25669885 22000412 26986935 29432156 20512932 20733051 21926987 25012665 25833949 27694884 11907259 18997788 25482201 25750436 24581499 23091007 27114510 19820702 25306918 21300909 32707033 32152539 11535616 20360068 22100920 33310066 17598981 25852190 25673878 28404789 24151075 23345399 17360335 22193957 28514442 21335556 26912231 23791783 26811472 25246557 11274370 21937719 11030144 19407811 25241761 28096334 20212161 25505175 30341343
E2F4 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15510213
CDC20 CDC16 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9628895 12956947 20360068 26811472 24100295 26496610 23007648 24464857 18997788 12196507 27114510 25306918 23443559
MAD2L1 CDC27 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 21772247 8284719
MAD2L1 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9736712 20212161 16189514
TP53 CDCA8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
CEP135 CENPJ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23511974 20531387
E2F4 TTK â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17981789 11799066
E2F4 UBE2C â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17671431
HSP90AA1 TP53 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
KNSTRN MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TTK MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TTK RPS6KA1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TTK TACC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15304323
CENPJ CEP152 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
CDC20 CDK2 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
CDK2 FZR1 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
NDC80 SPC24 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
HSP90AA1 LRRK2 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
MAD2L1 TTK â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
CDC20 UBE2C â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
FZR1 UBE2C â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
BUB1B CASC5 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
CCNB1 FZR1 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
CCNB1 CDC20 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
MAD2L1 CDC20 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 21772247 8284719
MAD2L1 MAD1L1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 6785080 18692475
MAD2L1 MAD1L1 â—¼   COLOCALIZATION ✅ 0.98 0.98 mint 21772247 8284719
MAD1L1 MAD2L1 â—¼   COLOCALIZATION ✅ 0.98 0.98 mint 21772247 8284719
BUB1B CDC16 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CCNB1 CDK2 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CDC27 MAD2L1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
BUB1B CDC27 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
NDC80 NUF2 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CDC16 MAD2L1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
BUB1B MAD2L1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MAD1L1 MAD2L1 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
CDC16 CDC20 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
CDC16 CDC27 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BUB1B CDC20 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CCNB1 CDK1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CDC16 FZR1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CDC20 MAD2L1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CDC20 CDC27 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CDC27 FZR1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
TTK ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18794806 28661474
CDK1 ABL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 19651622 17081983 2183353 18691976 18452278 18669648
ABL1 RAD52 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 12379650 29590107 20841568 14757045 21804533
CDK1 BUB1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20016069 23637705 29971233 23345399 23079597 26259146 17785528 20633640 19015317 33207204
BUB1B CDC20 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 63.0 1.0 Omnipath 11535616 23443559 11030144 25383541 19098431 23239745 18997788 22000412 15525512 25750436 12196507 16647857 23791783 25482201 25505175 25502805 22100920 25246557 20512932 11907259 25852190 21937719 11702782 20733051 25669885 25306918 19820702 22566641 26811472 25241761 25833949 25012665 27114510 24464857 21407176 17598981 23643811 19407811 23091007 17360335 11274370 18591651 24581499 20360068 26986935 31515488 25673878 21926987 24151075
E2F4 CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17531812 15855772 22508987
TP53 CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 12874009 14627709 10051609 11313928 17942917 11892838 15710382 20395210 19470724 12379461 11071927 11522645 15737644 11162602
CDC27 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19652693 18590585 7575488 17303408 12124778 17660363 16123593 15279786 15917306
CDK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23799914 34224728 20117088 16784539 24358021 24508230 19470789 10973963 17283331 20228808 18347064 11242082 12397081 10362260 24582498 15582998 20367638 1833185 12447691 9001210 2570636 24101512 23543736 11331587 12524548 22726437 27626412
CDC16 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19652693 18590585 7575488 17303408 12124778 17660363 16123593 15279786 15917306
CDC20 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 19652693 18590585 7575488 17303408 12124778 17660363 15279786 15917306
CDC27 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 9405394 17187060 24100295 7736578 21043528 10922056 26496610 9356466 25306918 12956947 20733055 22193957 27114510 16648845 9628895 14657031 20360068 16364912 10500174
CDK1 CDC16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 19652693 18590585 7575488 16565220 17303408 18420821 12124778 17660363 16964243 14657031 15279786 15917306
CDC16 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 9405394 17187060 24100295 7736578 21043528 10922056 26496610 9356466 25306918 12956947 20733055 22193957 27114510 16648845 9628895 14657031 20360068 16364912 10500174
CDK1 CDC20 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17596790 17660363 18414028 18543256 18590585 18995830 19652693 19686080 7575488 9892021
CDC27 CDC20 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 25156254 12956947 9736712 17443186 22014574 9637688 24781523 16189514 14561775 12196507
MAD2L1 CDC20 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 89.0 1.0 Omnipath 23443559 20212161 20081372 16525508 9637688 25383541 19098431 23239745 18997788 19143472 21335556 25750436 12196507 15182668 19826003 21743465 16647857 23791783 9736712 25482201 21772247 22100920 20512932 11804586 26496610 16189514 14561775 25092294 11702782 25669885 14607335 25306918 26811472 11438673 21525009 25012665 17443186 21041666 11707408 23754430 18794143 21407176 22340593 24464857 9628895 23643811 17360335 11274370 15694304 24581499 20360068 18592005 26986935 21300909 16497171 10700282 18318601 20054826 25673878 18022367 17443180 21926987 24151075
CDC20 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 25156254 12956947 9736712 17443186 22014574 9637688 24781523 16189514 14561775 12196507
CDK1 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19652693 18590585 7575488 16565220 17303408 29084198 33819340 12124778 17570479 17660363 14657031 15279786 15917306
FZR1 CDC27 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12797865 12956947 23029392 18662541 9637688 15916961 22014574 21241890 10500174 26963853
CDC27 FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12797865 12956947 23029392 18662541 9637688 15916961 22014574 21241890 10500174 26963853
TTK CDCA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19007248 18243099 19228686 19530738 18946085
TP53 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 10825186 11593387 12874009 19472317 10514438 11313928 16807237 8270002 17942917 9275177 20395210 11032828 19861536 12889596 19067706
E2F4 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15510213 17671431 11799067 11032828 17121828 17531812
E2F4 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15510213 16135806
CDK1 USP16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10077596 16189514 28380042 24013421
CDK1 KIF11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 26615533 19007248 16565220 19691289 19001501 28487562 19664994 20068231 16455663 25660025 19690332 8548803 21522128 19413330 9235942 20068230
CDK1 NINL â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20864540 21505454 20890132
CDK1 MAPK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20236090
CDK1 PRC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 29484112 18691976 22621898 17351640 17438553 17512944 16603632 30992425 20633640 23940115 9885575 16964243 27551054 34158398
CDK1 KIF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20368358 29230353
CDK1 ESPL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 25921067 12771378 15989971 17484111 11747808 21743463 22870341 16868023
CDK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 24173284 12767922 1584757 20661218 26029996 2141171 9467949 17570479 20808790 7862459 11327730 11078726 27726420 8357826 16713569 2156209
CDK2 FZR1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10323868 10375532 16582612 12730199
E2F4 CDK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17531812 22447046
CDK2 FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 11598127 15577895 9736735 12560341 15558010 20068231 10548110 16123593 15840442 18669648
CDK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 24173284 9315650 19413330 19664995 16083285 1088347 16552184 10884347 17570479 10747897 25241761 7624134 11687964 17287340 92065884 12064478 19556892 14640983 10348343 14702041
CHEK2 TP53 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 10710310 10673501 10570149 10673500
TP53 CHEK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15326376 19435816 10531348 19395378 15044452
TTK CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 27885363 15618221 10973490 19151762
CHEK2 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 111.0 1.0 Omnipath 18778462 25545885 16893723 15254178 18833288 23892398 12052256 18319725 25372714 15459660 20514219 25174607 28140789 17339337 22420423 18566216 20950777 20651945 15810020 15700044 22891162 17157788 11551930 18725978 10724175 15467443 23351141 20096447 11063934 11709713 15659650 12242661 10656682 15140942 20041275 11728459 18614044 12781359 22649771 18812180 11173129 10570149 15279785 20081365 20860841 11875057 22778557 19923893 24553354 22797063 26384650 23316480 15489221 19788416 10801407 21187893 9843217 9733514 10710310 24358900 21526939 23843721 29805302 9733515 25404613 12548019 21625617 10673501 11447225 17118344 26610585 19544417 28038466 12810724 25823026 15024084 17464182 15862297 19933256 20526329 12111733 20183804 23144912
E2F4 RBBP5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17531812 11799066
TP53 FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22466965 18811981 16557594 24492005
TP53 HSP90AA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15358769 15284248 24451373 18996350
HSP90AA1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12427754 10557093 21460846 16713569 11507088
TTK HSPA9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17573779
TTK MAD1L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 29868582 29162720 32202322 28072388
MAD1L1 MAD2L1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 31467278 32814053 16713569 10660610 21988832 21772247 16189514 26258632 26496610 21525009 25012665 21041666 11459826 11707408 18692475 32296183 15694304 24581499 26986935 29997244 18318601 31515488 22493223
TTK PRC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12686615 14657364
TTK TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19332559 27885363 23700430 22852086 23948487