Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
WASHC3 NDC80 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
WASHC3 PCM1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
CDC25C PLK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11897663 8703070
NDC80 DCTN1 â—¼   COLOCALIZATION 2.0 0.8 intact 8057081 20664522
DYNLL1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT HSPA1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPB1 PRPF19 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
KNSTRN HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
MAPRE3 MAPRE1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PLK1 BUB1B â—¼   PHOSPHORYLATION ✅ + 0.81 0.81 Signor 23079597
NDC80 SPC25 â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
KIF2B SPC24 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KIF2B SPC25 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SPAG5 DISC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 31413325
SPAG5 PCM1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26297806 34079125
NDC80 SPC24 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
SPC24 SGF29 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DCTN1 DISC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17043677 31413325 90000000
PLK1 SPAG5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27173435 25659891 26291670
PCM1 PLK1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23345402 26638075 34079125
PLK1 CDC25C â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 14532005 5216753
PLK1 DCTN1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 12852857 34079125
PCM1 HMMR â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26638075 34079125
DCTN1 MAPRE3 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
SPC24 SPC25 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
ZWINT SPC24 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 20360068 15824131 24981860 26496610 26186194 28514442
ZWINT SPC25 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 20360068 24981860 26496610 26186194 28514442
BUB1B ZWINT â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
SPC25 ZWINT â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
SPC24 ZWINT â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
NDC80 SGF29 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
HSPA1A HSPA6 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
NDC80 WASHC3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HuRI 32296183
PCM1 NDC80 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 27107012 26638075 34079125
NDC80 ZWINT â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
CDC25C PLK1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
AURKA KIF11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15630414 17939994
AURKA MAPRE3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19696028
KNSTRN MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TTK MAPK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAPK6 PLK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PLK1 CCNB1 â—¼   PHOSPHORYLATION ✅ + 0.91 0.91 Signor 11242082
AURKA TACC3 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
SPC24 SPC25 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
NDC80 SPC24 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
CKS2 CCNB1 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 33961781 30674583 18471975 26496610 28514442 19786724
BUB1B PLK1 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
SHPRH KNSTRN â—¼   KO_DOWN_REGULATES ✅ - -0.94 0.93 PKG 28854368
AURKA TACC3 â—¼   PHOSPHORYLATION ✅ + 0.93 0.93 Signor 17545617
DCTN1 MAPRE1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
SPC25 NDC80 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 14699129 14681455 20360068 28514442 15961401 33961781 24981860 22939629 26186194 25416956 34079125
CCNB1 CKS2 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
NDC80 SPC25 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
MAPRE1 MAPRE3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PLK1 KIF2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 22535524 25504441
AURKA DLGAP5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15987997 18220336 16631581 19690332 18669648
AURKA PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 18566290 23618492 27721411 24338364 15713655 28126323 34260926 19364923 33805672 33771996 32284347 27504491 33898950 10980711 26206521 21474997 32060423 27662907 28994651 33963314 18615013 23695676 34197606 18669648 25925375 26114094 19228686 28591578 22281053 18691976 20603326 15611664 27068477 27908669 26919439 26012549 18477460 34140642 25660017 27899378 19369195 21454580 25871386 24349352 12207013 20869364 11854496 20633640 28351953 24667170 25042804
AURKA TACC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 23861900 31932847 25596274 26186194 17060449 21297582 20566684 14602875 17545617 23918938 16172205 15687499 30344944 26090906 26134678
PLK1 BUB1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 23695676 19228686 17376779 27568981 23079597 26259146 27308323 17785528 19015317 22566210
PLK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 20404109 16854412 26899266 19364923 25362646 20126263 12524548 26729093 11242082 12447691
PLK1 CDC25C â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11073952 17596790 18931676 19270156 19622404 19686080 8127874
PLK1 CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 14968113 19622404 11202906 10980711 20668692 19597481 19686080 19270156 12595692 16189514 19503101 17634129 19607708 14532005 24525428 27038604 22852086 16753148 17596790 28396830 17307877 11897663 18931676
DYNLL1 DCTN1 â—¼   PHYSICAL_INTERACTION 28.0 1.0 Reactome 17274799 9490716 10679020 10562278 11306556 24891604 16723730 18086915 17283181 18664496 11035033 25453831 18046453 11285137 19564404 8642258 12198549 15728195 10903204 15878873 7691276 8909537 23839779 9150144 10559986 25233431 10036229 24806965
PLK1 DCTN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21931181 28415805 23985322 23661607 20679239
POLM KNSTRN â—¼   KO_DOWN_REGULATES ✅ - -1.04 1.03 PKG 28854368
POLM SKA3 â—¼   KO_DOWN_REGULATES ✅ - -1.09 1.08 PKG 28854368
SHPRH SHPRH â—¼   KO_DOWN_REGULATES ✅ - -4.0 3.99 PKG 28854368