Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ARF6 KIF23 â—¼   COLOCALIZATION 2.0 0.8 intact 22522702 8395701
NFATC2 MEF2D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11796223 10944115
CALU TTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SNCB APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCB SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCB RYBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PLK1 SNCB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19889641
TOPBP1 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17006541 5219150
TOPBP1 AKT1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 17006541 5219150
GRK6 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ERP44 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBQLN1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PLK1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP PLSCR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CBR3 RAB35 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
DAPK1 CDC42EP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
CDK2 MCM7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10523313 10373557
DAPK1 GTF2F1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
IGF2R GGA3 â—¼   COLOCALIZATION 2.0 0.8 intact 16977309 5219086
LNX1 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LNX1 RPIA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
MAX MGA â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
PLK2 PLK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 0904229106 19706541
SF1 PLSCR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PRKRIP1 SNW1 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
PSMD4 PSMA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16990800 5219132
PSMD4 PSMB7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16990800 5219132
TBPL1 RAB35 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RBM42 SNRPD2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
RYBP SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YY1 SF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
SNW1 UBQLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
STT3B TTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RAD23B UBQLN1 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
APP SNCA â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
MDC1 HMGCS1 â—¼   KO_UP_REGULATES ✅ + 0.81 0.81 PKG 28854368
ERP44 DAPK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ERP44 DCP1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LNX1 TRAF4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32296183 29121065
LZTS2 SOGA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PRKRIP1 SNRPD2 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
RYBP VRK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 34316702
PPIH SNRPD2 â—¼   PHYSICAL_INTERACTION 827.0 0.82 STRING 36370105
LZTS2 TSSC4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TSSC4 EAPP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28561026 28514442 26186194 33961781
TSSC4 SNW1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28561026 28514442 26186194 33961781
LZTS2 EAPP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PLK1 HSF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 18794143 27173435
MAX RYBP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 29028833 27705803
SNRPD2 CLNS1A â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 22365833 8293266
MIB1 DAPK1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12351649 15048887
AKT1 ARNT â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 28205554 28628118 15833858
SLC9A3R1 EZR â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 11285285 5213905
MDC1 TOPBP1 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
SNRPD2 TSSC4 â—¼   PHYSICAL_INTERACTION 859.0 0.85 STRING 36370105
PCNA CALU â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22863883 26030842
RAD23B PSMD4 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 20059542 7307429
MED29 MED22 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 15175163 24981860 24882805 14638676
RNF113A SNW1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
RNF113A SNRPD2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MGA RYBP â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
ARF6 GGA3 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CAND1 CAND2 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
SNCA SNCAIP â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
MDC1 TOPBP1 â—¼   KO_UP_REGULATES ✅ + 0.89 0.89 PKG 28854368
LZTS2 UBASH3B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
CHAF1B PCNA â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
PCNA CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10930425
SNCB SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11683992 23630590
PLK1 CENPQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 25670858
MIB1 DAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12351649
YY1 HSF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
MCMBP MCM7 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24299456
EZR SLC9A3R1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
HSF1 HSPA1A â—¼   PHYSICAL_INTERACTION 908.0 0.9 STRING 36370105
CLNS1A SNRPD2 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
ARF6 KIF23 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
MCM7 WDHD1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
PCNA CDK2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 28514442 33961781 26496610 7903056 9545286 26186194 12361598 21319273 10930425 29510343
PSMD4 UBQLN1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
MCM7 MCMBP â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
CDK2 PCNA â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
SNRPD2 SNW1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
NCAPG NCAPH â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
GGA3 IGF2R â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMA3 PSMB7 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMB7 PSMD4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMD4 RAD23B â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PSMB3 PSMB7 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PSMB3 PSMD4 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
PSMA3 PSMD4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PSMA3 PSMB3 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
PCNA CHEK1 â—¼   PHYSICAL_INTERACTION 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA CHEK1 â—¼   SHARES_COMPLEX 47.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 1974050 19793801 19847258 20051983 22021614 23414611
PCNA CHAF1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10648606 20112283
PLK2 SNCB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21849493 19889641
GRK5 SNCB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10852916
PLK3 SNCB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21849493 19889641
AKT1 CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 20832017 18691976 23108403 17418864 20068231 12062056 15107605 17570479 19664995 18669648 26091525
AKT1 TOPBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 24081328 17913746 33556369 17006541
AKT1 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18354084 29665367
CAND1 COMMD1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 17183367 21778237 23563313 25355947 17497243 15799966
CDK2 MCM7 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 LIG3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 17040896
CDK2 CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21765472 21965652 21907702 18983824 24242917
TOPBP1 CHEK1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
CHEK1 MCM7 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
TOPBP1 CHEK1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
TOPBP1 CHEK1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 11756412 11877377 12086603 12466554 12766152 12875843 14624239 14657033 14726013 14988723 15136767 15175241 15189446 15459660 15485915 15703371 15798197 16530042 16697054 16713580 16805667 16880517 16885023 16934469 17035102 17102137 17116885 17141802 17296725 17303408 17384638 17582221 18157158 18451105 18469862 18677104 18931676 18995830 19158510 19217833 19225445 19258535 19282663 19342888 19622404 19686080 1974050 19793801 19847258 20051983 22021614 23414611
CHEK1 MCM7 â—¼   DOWN_REGULATES ✅ - 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CHEK1 MCM7 â—¼   REGULATES ✅ 43.0 1.0 ACSN 10884395 11877377 11900249 12086603 12648680 12766152 12875843 14624239 14726013 14988723 15136767 15175241 15459660 15703371 15798197 16697054 16713580 16805667 16880517 16885023 16934469 17102137 17116885 17141802 17296725 17303408 17384638 17493829 17582221 17884153 18469862 18677104 18995830 19282663 19342888 19622404 19793801 19809470 19847258 20051983 20478261 8943031 9524127
CSNK1A1 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 20203178 10852916 10617630 11813001 25009465 24798925
SLC9A3R1 EZR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 11285285 20937695 11684085 9314537 15020681 23414517
GRK5 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 25915624 10852916 11813001 10617630 26614013 16957079
GRK6 SLC9A3R1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 20166139 17895247 18088087 18452278 30696771 19413330 10446210 19664995 18669648 15302935
HSF1 HSPA1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 9699716 21932106 16460681 2674689 16012946 24041570 1508207 22797943 9011567 1717345 17897941 20692357 23212905 23874968
PLK1 HSF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18794143 27354066 19934326 15661742
MAX MGA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21988832 20936779 25609649 27705803 7954804
PLK1 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19004816 21849493 28067771 19889641
PLK1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21253604 23226345 22248053
PLK2 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 21050448 25915624 25009465 19889641 28829427 19004816 21849493 28900007 22828320 23677647 25908633 34234930 28648742 22988096 22248692 28592329
PLK3 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 19889641 26120904 22828320 23677647 21849493 25009465
PLK3 VRK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 20068231 17617371 19103756
MDC1 CTSV â—¼   KO_UP_REGULATES ✅ + 1.1 1.1 PKG 28854368
MDC1 DIAPH2 â—¼   KO_DOWN_REGULATES ✅ - -1.45 1.44 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368