Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CHEK1 TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5218401 16511572
SNCB COPS3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
COPS3 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PLK1 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PLK2 PLK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 0904229106 19706541
PLK1 TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 7266226 19833129
PLK1 SNCB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19889641
TP53 PLK3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11447225 11551930
TP53 PLK3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21394211 16581545
SNCB TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12867415
SNCA PIAS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCB PIAS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
GRK6 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WDR61 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCB APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
LNX1 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RYBP SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
WDR61 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCB SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCB RYBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CENPT SNCB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SNCB WDR61 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
APP SNCA â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
PIAS1 TP53 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
CHEK1 TP53 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
SNCA SNCAIP â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
HSPA1A TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7811761 16713569 8729618
TP53 HSPA1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7811761 16713569 8729618
SNCB SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11683992 23630590
TP53 CHEK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 21546904 11158294 20190799 19435816 18632613 15016801 19395378 11152453 18753293
AKT1 CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 20832017 18691976 23108403 17418864 20068231 12062056 15107605 17570479 19664995 18669648 26091525
CHEK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 20950777 18778462 25545885 18677104 20860841 15798197 19793801 22891162 16511572 23852422 16713569 15865930 11551930 19923893 15467443 11709713 21748595 17116885 15659650 17582221 26384650 10673501 17384638 23966620 23892398 17118344 9765199 15140942 19788416 10801407 18319725 12781359 12897801 25823026 15459660 23296650 15024084 17296725 17102137 11896572 17339337 19933256 20526329 28140789
TP53 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17172872 17981789 15024021 22405092 20962589 24076372 23948487 15016801 22184120 19713933 16369493 23474762
PLK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22653443 19833129 16753148 23948487
PLK1 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19004816 21849493 28067771 19889641
PLK2 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 21050448 25915624 25009465 19889641 28829427 19004816 21849493 28900007 22828320 23677647 25908633 34234930 28648742 22988096 22248692 28592329
PLK2 SNCB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21849493 19889641
PLK3 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 15489221 24395704 11709713 10801407 15254178 16581545 12242661 16713569 12111733 11551930 19607708 10673501 11875057 11447225 12548019
PLK3 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 19889641 26120904 22828320 23677647 21849493 25009465
PLK3 SNCB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21849493 19889641
TP53 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12485897 18661553 19763735
PIAS1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25241761 15133049 10380882 20805487 11867732 16713569 11583632 11788578
GRK5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 27326393 15053879 22223642 20124405 26029824 26226012
GRK5 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 25915624 10852916 11813001 10617630 26614013 16957079
GRK5 SNCB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 10852916