Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CTSL SERPINB13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12809493 12504904
E2F1 CTSV â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23542171
CTSV SERPINB13 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12809493 12504904
SRC DCC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21849478 26323693
PGR FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18391971
CSTA CTSV â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
POLM CTSL â—¼   KO_DOWN_REGULATES ✅ - -0.85 0.84 PKG 28854368
BUB1 APC â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11283619 25241761
APC CTNNA1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MLH3 MLH1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 10615123 11292842 27229929 24443562 32814343
CSTA CTSL â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
SRC DCC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 15557120 15494734 15494732
E2F1 DCC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12629508
RB1 E2F1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5219804 17380128
MDC1 FTH1 â—¼   KO_UP_REGULATES ✅ + 0.98 0.98 PKG 28854368
PLK2 SNCB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21849493 19889641
E2F1 RB1 â—¼   PHYSICAL_INTERACTION 18.0 1.0 ACSN 11877377 15175241 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 19793801 20029420 21060331 21337561 24254977 7575488 7935440
E2F1 RB1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 11877377 15175241 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 19793801 20029420 21060331 21337561 24254977 7575488 7935440
E2F1 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 11533237 16081466 16738312 16188218 15618023 14681231 16230367 15985428 8264596 18583990 16601104 14627987 15016799 11268000 10490838 11818069
RB1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 90.0 1.0 Omnipath 17145710 23472054 12502741 22078878 8896460 12397079 9315635 20839231 16249186 11839806 8255752 11713253 20871633 15837424 8346196 19249677 16360038 8626527 12096339 15485814 16374512 18391203 9125176 16766265 9468140 8816798 12598654 10393912 9400991 9632788 12947005 19477924 15485920 17380128 10523633 10869426 7828850 18216119 8657117 12963846 25257171 17488475 28074012 15670817 11583618 7739537 10499802 8413249 11090181 8230483 22768064 29521627 10207050 9553123 7958924 11420730 23001041 16496386 9501179 19058874 1388726 9422723
MLH1 MLH3 â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 15703371 16612326 16697054 18157157 18406444 19847258 20478261
MDC1 CTSV â—¼   KO_UP_REGULATES ✅ + 1.1 1.1 PKG 28854368
POLM CTSV â—¼   KO_DOWN_REGULATES ✅ - -1.52 1.51 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368