HRAS
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
RPA2
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10882098
10757793
|
CDK2
|
RPA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10882098
10757793
|
CDK2
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
10882098
10757793
|
TP53
|
FANCC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9063748
|
TP53
|
FANCC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
MLH1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15781865
|
BPNT2
|
MLH3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
MSH6
|
MSH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6548274
9774676
|
MSH3
|
MSH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6548274
9774676
|
MYC
|
MSH2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12808131
11983916
|
TP53
|
MSH2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12209975
|
AKT1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
17942906
9804616
|
TP53
|
PMS2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
POLD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11375983
|
POLD1
|
POLD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17145710
10852724
|
SSBP1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19066201
|
AR
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19481544
7103716
|
TP53
|
MAP2K1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10529175
9724739
|
MYCN
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20145147
|
TP53
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7915517
|
TP53
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
RASA1
|
HRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5221569
9219684
|
AR
|
IGFBP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16825320
|
SMAD1
|
ZNF510
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
AR
|
SMAD1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
5219486
17183365
|
ATM
|
EXO1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.8
|
0.8
|
Signor
|
20019063
|
SMAD1
|
DVL1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
12650946
|
MYC
|
MSH3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17314511
29467282
|
MYC
|
RFC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17353931
29467282
|
MYC
|
RFC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17314511
29467282
|
MYC
|
RFC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17314511
29467282
|
SMAD1
|
LEF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
10890911
15750622
|
MSH3
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HuRI
|
32296183
|
PMS2
|
FAN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
25659891
27880917
26496610
20603073
20603015
17148452
|
RPA1
|
XPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
PCNA
|
EXO1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
15225546
16189514
14676842
25833945
|
AKT1
|
MSH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28628118
24412244
28205554
|
RPA1
|
RPA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
854.0
|
0.85
|
STRING
|
36370105
|
CDK2
|
TP53
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.86
|
0.86
|
Signor
|
24173284
|
MLH1
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
15225546
32814904
28439008
|
EXO1
|
PMS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
865.0
|
0.86
|
STRING
|
36370105
|
MYC
|
RFC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
17314511
30415952
29467282
|
AKT1
|
AR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
FAN1
|
MLH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
EXO1
|
PMS2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
14676842
11429708
11427529
17148452
|
MLH3
|
MSH4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
32814904
12095912
|
PMS2
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
15225546
28439008
17148452
|
POLD2
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.88
|
0.88
|
mint
|
31449058
|
POLD1
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
MLH1
|
FAN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
25659891
32296183
27880917
29051491
26496610
20603073
20603015
33961781
17148452
|
MSH4
|
MLH1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
32814904
16189514
10928988
|
MLH3
|
MLH1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24443562
32814343
11292842
33961781
27229929
10615123
|
MYC
|
MLH1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12584560
29467282
|
PMS2
|
MSH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12799449
10748159
17148452
|
MYC
|
MSH6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
17353931
17314511
29467282
|
PMS2
|
MSH6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12799449
10748159
17148452
|
RFC4
|
MYC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21150319
17353931
30415952
29467282
|
RPA1
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA3
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
RPA2
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
18171670
11080452
17965729
|
TP53
|
ATM
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
9843217
9733515
9733514
|
PPP2CB
|
ATM
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
15510216
|
ATM
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15546863
15899889
|
PCNA
|
CDK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10930425
|
EXO1
|
MLH1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
19015241
21533173
32814904
12810663
11429708
14676842
12414623
11427529
22222486
17148452
|
EXO1
|
MSH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16189514
9788596
10856833
11429708
14676842
12414623
33961781
19015241
11427529
22222486
|
TP73
|
MLH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11309270
18829110
21245298
|
TP53
|
MLH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
18431400
15781865
|
MYCN
|
MLH3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16093321
|
MYC
|
MSH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28628118
17314511
12584560
29467282
28205554
30415952
|
TP53
|
MSH2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11350971
8630028
|
SMAD1
|
MYC
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
3.0
|
0.9
|
ACSN
|
15576399
22290435
22761862
|
MYC
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16846534
16489011
18562319
|
MYC
|
POLD2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
MYC
|
RFC2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12747840
|
MYC
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
12695333
|
TP53
|
PMS2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15781865
|
POLD2
|
POLD3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16000169
10852724
16510448
|
TP53
|
POLD2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19861536
|
TP73
|
POLD2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19861536
|
AR
|
IGFBP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20610535
23859805
|
LEF1
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16741972
16474850
19351848
|
MSH6
|
PMS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
903.0
|
0.9
|
STRING
|
36370105
|
MSH2
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
909.0
|
0.91
|
STRING
|
36370105
|
FBP1
|
FBP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.91
|
0.91
|
HuRI
|
32296183
|
MSH2
|
PMS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
911.0
|
0.91
|
STRING
|
36370105
|
MSH3
|
MSH6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
ATM
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
915.0
|
0.91
|
STRING
|
36370105
|
POLD2
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
916.0
|
0.91
|
STRING
|
36370105
|
MLH1
|
MSH6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
917.0
|
0.91
|
STRING
|
36370105
|
MSH4
|
MSH5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.92
|
STRING
|
36370105
|
RPA3
|
RPA2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
24126761
|
POLD3
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
927.0
|
0.92
|
STRING
|
36370105
|
MSH6
|
MLH1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
12799449
30770470
10783165
10748159
|
MLH1
|
MSH3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
29892012
25416956
17148452
|
PCNA
|
MSH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
15225546
12171929
16189514
8858149
|
RFC2
|
RFC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
22939629
9488738
26344197
24981860
|
MSH2
|
MLH1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
25241761
10783165
31843968
30770470
12799449
10748159
|
MLH1
|
MSH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
952.0
|
0.95
|
STRING
|
36370105
|
PCNA
|
CDK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
12361598
28514442
26496610
29510343
9545286
33961781
26186194
7903056
21319273
10930425
|
RFC2
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
9228079
12171929
24958773
26496610
8093561
|
PCNA
|
RFC3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
12171929
24958773
12766176
14657243
10051561
9092549
26344197
|
RFC3
|
RFC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
33961781
24981860
22939629
26344197
|
RFC5
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
9228079
12171929
16189514
24958773
8999859
|
RPA1
|
RPA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
24207024
22939629
26399832
26496610
24981860
16514417
19214185
26344197
|
EXO1
|
MLH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
MSH3
|
MSH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16025128
8942985
10029069
8805365
14657349
33961781
9774676
22939629
22179786
19377479
|
MSH3
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
12171929
25416956
32296183
11274057
11005803
|
MSH5
|
MSH4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
16189514
22401567
32814343
10029069
9787078
16122992
16397227
15489243
12591739
|
MSH6
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
12171929
16189514
15225546
24958773
21725088
26496610
11005803
11274057
22939629
22232658
26344197
|
PCNA
|
RFC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
12171929
12192049
22939629
9649448
15225546
24958773
12045192
26496610
10353443
8861969
30301766
9092549
8999859
12400013
26344197
|
RFC1
|
RFC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
9488738
14681455
15655353
18245774
22939629
26344197
|
PCNA
|
RFC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
9228079
12171929
16189514
22939629
24958773
26496610
10051561
12400013
|
EXO1
|
MSH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
RPA1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
MSH6
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
974.0
|
0.97
|
STRING
|
36370105
|
HRAS
|
RASA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
RFC1
|
RFC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.98
|
0.98
|
HIPPIE
|
28514442
9488738
22939629
14681455
33961781
18245774
9092549
26344197
|
RFC1
|
RFC5
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.98
|
0.98
|
HIPPIE
|
28514442
9488738
14681455
33961781
18245774
22939629
26344197
|
RPA1
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
LIG1
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
984.0
|
0.98
|
STRING
|
36370105
|
PMS2
|
MLH1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
15225546
20706999
18206974
16338176
11793469
20533529
18768816
10037723
12799449
12810663
26496610
20978114
12584560
16083711
30770470
11292842
17581638
11429708
22939629
19015241
25077178
10748159
25502805
33961781
14676842
22252508
17148452
|
MSH6
|
MSH2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
19377479
25241761
10783165
8942985
9428522
10029069
26496610
10856833
14657349
10748159
33961781
9774676
22939629
26344197
15064730
|
RFC3
|
RFC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
9488738
8692848
14681455
18245774
22939629
26344197
|
RFC2
|
RFC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
9228079
9751713
28514442
9488738
22939629
8692848
15655353
33961781
24981860
16582606
9092549
26344197
|
RFC3
|
RFC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
28514442
32296183
9488738
22939629
8692848
33961781
9092549
26344197
|
CDK2
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
PCNA
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
POLD1
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
PCNA
|
RFC5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
POLD2
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PCNA
|
RFC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
RFC1
|
RFC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PCNA
|
RFC3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PCNA
|
RFC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
RPA1
|
RPA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
PCNA
|
RFC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
RFC2
|
RFC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
RFC3
|
RFC4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CDK2
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
9781043
16322221
16123081
11292842
10928988
|
MLH1
|
ATM
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
9781043
16322221
16123081
11292842
10928988
|
ATM
|
MLH3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
9781043
16322221
16123081
11292842
10928988
|
ATM
|
EXO1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
54.0
|
1.0
|
ACSN
|
11331603
11438669
11804596
11877377
12086603
12556884
12607003
14988723
15136767
15140942
15175241
15459660
15485915
15798197
15867354
15964794
16163361
16332722
16581787
16713580
16731533
16805667
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17713585
18006705
18048416
18469862
18511906
18583988
18716619
18756267
18995830
19151707
19282663
19342888
19357644
19490890
19622404
19788416
19793801
19793861
19841479
20019063
20051983
21376743
23847781
9168117
9858600
|
ATM
|
RPA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
54.0
|
1.0
|
ACSN
|
11331603
11438669
11804596
11877377
12086603
12556884
12607003
14988723
15136767
15140942
15175241
15459660
15485915
15798197
15867354
15964794
16163361
16332722
16581787
16713580
16731533
16805667
16858402
17102137
17116885
17296725
17303408
17384638
17582221
17713585
18006705
18048416
18469862
18511906
18583988
18716619
18756267
18995830
19151707
19282663
19342888
19357644
19490890
19622404
19788416
19793801
19793861
19841479
20019063
20051983
21376743
23847781
9168117
9858600
|
MSH2
|
ATM
|
â—¼ UP_REGULATES
|
✅
|
+
|
20.0
|
1.0
|
ACSN
|
12556884
12947387
15136767
15703371
16332722
16612326
16697054
16713580
16858402
17303408
18157157
18406444
18543256
19151707
19473888
19595721
19596235
19596236
19847258
20478261
|
MLH1
|
ATM
|
â—¼ UP_REGULATES
|
✅
|
+
|
16.0
|
1.0
|
ACSN
|
12556884
15136767
15703371
16332722
16612326
16697054
16713580
16858402
17303408
17581638
18157157
18406444
18543256
19151707
19847258
20478261
|
MSH6
|
ATM
|
â—¼ UP_REGULATES
|
✅
|
+
|
20.0
|
1.0
|
ACSN
|
12556884
12947387
15136767
15703371
16332722
16612326
16697054
16713580
16858402
17303408
18157157
18406444
18543256
19151707
19473888
19595721
19596235
19596236
19847258
20478261
|
PMS2
|
ATM
|
â—¼ UP_REGULATES
|
✅
|
+
|
16.0
|
1.0
|
ACSN
|
12556884
15136767
15703371
16332722
16612326
16697054
16713580
16858402
17303408
17581638
18157157
18406444
18543256
19151707
19847258
20478261
|
ATM
|
RPA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
24.0
|
1.0
|
Omnipath
|
29875999
15964794
11877377
17303408
9725899
16163361
14872059
23847781
9139719
10713094
9295339
20860841
16731533
12607003
22977173
7171818
15459660
|
ATM
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
452.0
|
1.0
|
Omnipath
|
25301947
21720806
23549171
10713094
16501611
15077171
24886358
17570479
19375142
22028490
16916644
14712210
19303885
9407038
11927276
26700820
28356518
15226429
10723129
19788889
12064478
19705844
26673821
22179422
20931131
19062161
27030982
22891162
17157788
19056039
15758953
12049739
15361830
26620371
25865756
22615843
10196661
10656682
11313957
25088203
15140942
12519769
16319535
24469230
12776195
17234789
27511909
29238697
24608431
12927814
16783362
11875057
16436515
22778557
15181149
12702572
10500142
15178764
28842590
28145533
11591448
17855337
22726545
20206688
26824362
21317290
26104798
24704793
9765199
11314044
16906133
17174997
21593792
17967874
10771484
15585169
19625493
15178448
17596534
16288207
15048074
18353733
24057508
19535302
29344296
23708100
29872395
23705030
25043304
33761896
18431490
21404020
15024084
22559321
12151394
24078877
12080066
33982778
16893723
10958792
18289945
27183917
26337656
29170437
18765533
10744722
21748595
18056442
24820418
15489892
16390936
24086335
28140789
23091651
34523970
32001619
23418564
15279808
21317932
21188172
27559048
16818505
17616578
11551930
19010925
11709713
24711418
28654064
18339864
11173129
17486112
10570149
29774100
18381438
21994612
29558908
15258567
9372954
25860929
16858402
33692124
15775976
34107253
19923893
24958101
10436023
14752509
19962312
19071090
26438152
26093282
20123963
22444248
9843217
17525332
15456784
23533526
11780126
20353948
29290977
11096068
28102346
18855897
20372057
24395704
23890999
15725625
15806145
34103468
18345031
16997395
16293623
28477117
19828454
27630139
12071847
22002314
21315088
27177180
12645530
12890678
26113041
15794754
18560558
22099307
9885574
28903382
15665826
24877058
18332866
10611322
24380814
14871840
19934315
22975381
16489034
18406507
21440540
33687951
10608806
23892398
20730097
16914171
15782130
15177184
22055193
18490454
25867001
24349352
18045533
20663147
17535811
20506250
23982736
22375140
15700044
15279774
19266268
24358288
18697815
14729946
20637859
12242661
12771937
17371838
31940492
19409520
10528155
24037342
17257427
11121242
15310764
23148227
28915641
26928575
21423215
11865061
16949371
27810895
18449195
20711232
27389279
22213803
16713569
10446957
22797063
16478990
29048667
15489221
17241873
21187893
21441950
23907539
20005840
9733514
26244501
21614094
12082529
10467728
10714958
32061892
16636671
29147215
10673501
12091386
25202122
21465263
19544417
25823026
24078903
24038750
22198295
21480565
15177039
28182994
28208785
18674635
20183804
18818083
9925639
17712528
15254178
11483158
27940348
26675349
26261212
19717643
12606585
24559687
14871926
23150668
21329876
28153791
12518062
12767922
23824039
11711532
19251701
28118604
15078887
12393500
17456577
20976220
23380594
12519780
20810927
15533933
22420423
17108107
20145032
18032786
18785202
22037398
23184057
31968249
16729035
12588868
21614932
11546806
18614045
14757188
15029243
14968111
22649771
25512053
34496248
18604166
17609585
17976513
16223874
25433195
18985806
9363941
15159397
34282274
29301278
24505404
26056062
23577291
18272544
18715874
19536869
29334356
10801407
15155458
25201202
24376853
19907922
23525106
14643431
28340339
28051100
19085961
15212693
22201816
20026654
16322229
20080565
9733515
15632067
18672098
22577550
25691451
12637545
12548019
11672523
26984736
12324477
16552184
22084686
10864201
14744854
21532626
17118344
19482562
9561848
12511424
17668048
23358251
18511169
21460853
22022355
12939400
21415014
17292432
25651062
23168260
12111733
16648554
30361254
23678107
|
ATM
|
SMAD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
22588298
23277204
|
ATM
|
RPA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
17525332
11359916
|
ATM
|
EXO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
22.0
|
1.0
|
Omnipath
|
15964794
11877377
17303408
18756267
16163361
15867354
23847781
23675572
25956864
26240375
11438669
24705021
12607003
18048416
17525332
20019063
15459660
|
CDC14B
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
10644693
16713569
|
MYC
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
11274345
11283614
12545156
14536078
15147722
15155580
15279786
17055429
17303408
17550342
17558397
17660363
17873522
18590585
18636226
19887899
20027199
20237412
20551172
20581311
20713526
20818389
21406394
21733352
2191300
21919891
22067385
23140366
23869868
24954210
25002027
28536364
7575488
9618481
|
CDK2
|
MLH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
9781043
16322221
16123081
11292842
10928988
|
CDK2
|
MLH3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
9781043
16322221
16123081
11292842
10928988
|
MYC
|
CDK2
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
11274345
11283614
12545156
14536078
15147722
15155580
15279786
17055429
17303408
17550342
17558397
17660363
17873522
18590585
18636226
19887899
20027199
20237412
20551172
20581311
20713526
20818389
21406394
21733352
2191300
21919891
22067385
23140366
23869868
24954210
25002027
28536364
7575488
9618481
|
CDK2
|
RPA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
14536078
15147722
15175241
15279786
15677884
16581787
17038621
17102137
17116885
17296725
17303408
17582221
17660363
17713585
18590585
18636226
19793801
7575488
|
CDK2
|
RPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
14536078
15147722
15175241
15279786
15677884
16581787
17038621
17102137
17116885
17296725
17303408
17582221
17660363
17713585
18590585
18636226
19793801
7575488
|
CDK2
|
RPA3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
14536078
15147722
15175241
15279786
15677884
16581787
17038621
17102137
17116885
17296725
17303408
17582221
17660363
17713585
18590585
18636226
19793801
7575488
|
AKT1
|
CDK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
18354084
29665367
|
CDK2
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
8386367
27653698
17081983
19966300
18669648
29896817
17570479
20713526
17558397
15103331
22348395
20445224
|
CDK2
|
TP73
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
22002055
15985436
12676926
|
CDK2
|
LIG1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12851383
10930425
|
CDK2
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
39.0
|
1.0
|
Omnipath
|
24173284
9315650
19413330
19664995
16083285
1088347
16552184
10884347
17570479
10747897
25241761
7624134
11687964
17287340
92065884
12064478
19556892
14640983
10348343
14702041
|
PMS2
|
EXO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
20970388
17426132
14676842
16188885
16143102
|
MSH6
|
EXO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
20970388
17426132
14676842
16188885
16143102
|
PCNA
|
EXO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
21.0
|
1.0
|
ACSN
|
11438669
11756412
14624239
14676842
14726013
15474417
15703371
16697054
18048416
18087292
18584027
18756267
18809224
19490890
1974050
19772495
19847258
20019063
20478261
22021614
23414611
|
MSH3
|
EXO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
20970388
17426132
14676842
16188885
16143102
|
MSH2
|
EXO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
20970388
17426132
14676842
16188885
16143102
|
PCNA
|
EXO1
|
â—¼ SHARES_COMPLEX
|
|
|
21.0
|
1.0
|
ACSN
|
11438669
11756412
14624239
14676842
14726013
15474417
15703371
16697054
18048416
18087292
18584027
18756267
18809224
19490890
1974050
19772495
19847258
20019063
20478261
22021614
23414611
|
PCNA
|
EXO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
20970388
16189514
15225546
|
PCNA
|
MLH1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
20154325
22118461
11274057
23840062
|
MLH1
|
PMS2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
40.0
|
1.0
|
ACSN
|
10882712
11900249
12556884
12648680
12947387
15136767
15703371
16332722
16612326
16697054
16713580
16858402
17036055
17303408
17581638
17884153
18157157
18406444
18543256
18931676
19151707
19473888
19595721
19596235
19596236
19622404
19686080
19805513
19809470
19847258
20173781
20478261
21376743
22101340
22257761
22373527
22743550
22824526
23085398
24050180
|
MLH1
|
MLH3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
ACSN
|
15703371
16612326
16697054
18157157
18406444
19847258
20478261
|
MLH1
|
PMS2
|
â—¼ PROTEIN_INTERACTION
|
|
|
40.0
|
1.0
|
ACSN
|
10882712
11900249
12556884
12648680
12947387
15136767
15703371
16332722
16612326
16697054
16713580
16858402
17036055
17303408
17581638
17884153
18157157
18406444
18543256
18931676
19151707
19473888
19595721
19596235
19596236
19622404
19686080
19805513
19809470
19847258
20173781
20478261
21376743
22101340
22257761
22373527
22743550
22824526
23085398
24050180
|
MLH1
|
MLH3
|
â—¼ PROTEIN_INTERACTION
|
|
|
7.0
|
1.0
|
ACSN
|
15703371
16612326
16697054
18157157
18406444
19847258
20478261
|
MLH1
|
PMS2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
45.0
|
1.0
|
Omnipath
|
25077178
17145710
10748159
17148452
11429708
18206974
19015241
16338176
20706999
15225546
25502805
19022408
12584560
26496610
14676842
16083711
11793469
10037723
11292842
22252508
17581638
12799449
18768816
20533529
31515488
20978114
12810663
|
PCNA
|
MSH2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
20154325
22118461
11274057
23840062
|
MSH2
|
MSH3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
MSH2
|
MSH6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
26.0
|
1.0
|
ACSN
|
11307145
11948476
12556884
12947387
15136767
15703371
16332722
16612326
16697054
16713580
16858402
16879101
17129768
17303408
17395641
18157157
18406444
18543256
19151707
19473888
19595721
19596235
19596236
19847258
20478261
23507534
|
MSH2
|
MSH6
|
â—¼ SHARES_COMPLEX
|
|
|
26.0
|
1.0
|
ACSN
|
11307145
11948476
12556884
12947387
15136767
15703371
16332722
16612326
16697054
16713580
16858402
16879101
17129768
17303408
17395641
18157157
18406444
18543256
19151707
19473888
19595721
19596235
19596236
19847258
20478261
23507534
|
MSH2
|
MSH3
|
â—¼ SHARES_COMPLEX
|
|
|
20.0
|
1.0
|
ACSN
|
10882712
12947387
15703371
16612326
16697054
17036055
18157157
18406444
18469862
19473888
19595721
19596235
19596236
19686080
19772495
19805513
19847258
20478261
20655466
22101340
|
PCNA
|
MSH6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
Reactome
|
20713735
20154325
22118461
11274057
11441019
11005803
18326858
17984070
11809883
16188885
16143102
|
MYC
|
TGFB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
10432118
11274345
11283614
11875494
16327802
17558397
17873522
20027199
20237412
20551172
20581311
20713526
21093321
21372296
21406394
21765015
2191300
22067385
22461508
23124025
23390297
25002027
|
LEF1
|
MYC
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
19620402
18202148
17132729
19653274
|
MYC
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
10962037
10656696
8494784
10348347
19882681
16557594
19086036
15780936
14519204
16112647
11781835
7969121
11789587
9839551
|
MYC
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7597041
18358094
22911891
18809243
1280813111085504
11085504
|
PPP2CB
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
19131971
10026142
10995457
18042541
18559511
16987807
16680151
15048125
|
LEF1
|
MYC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
19751508
7542250
11967263
22290435
19623618
23343194
11955436
22270359
22761862
16039586
15810077
17143292
12051714
8666229
22943793
15576399
21151179
16940750
17306568
17666529
21285352
19619488
|
PMS2
|
TP73
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
18768816
|
LIG1
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9649448
19223468
22952233
10959839
|
POLD4
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
POLD1
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
POLD1
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
POLD4
|
POLD1
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD1
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
POLD1
|
POLD3
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
POLD1
|
POLD2
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLD1
|
POLD4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLD1
|
POLD3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLD1
|
POLD2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLD1
|
POLD2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
9286699
12403614
16510448
|
POLD1
|
POLD4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
12403614
16510448
|
POLD4
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
LIG1
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9649448
19223468
22952233
10959839
|
PCNA
|
POLD3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
POLD3
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD3
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
POLD4
|
POLD3
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
POLD3
|
POLD2
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLD2
|
POLD3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
POLD3
|
POLD4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
LIG1
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9649448
19223468
22952233
10959839
|
PCNA
|
POLD4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
POLD4
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
PCNA
|
POLD4
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
POLD4
|
POLD2
|
â—¼ SHARES_COMPLEX
|
|
|
11.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
27760120
27760777
|
POLD2
|
POLD4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
PCNA
|
POLD4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
PCNA
|
POLD4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
24022480
9038370
16510448
|
PCNA
|
RFC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
19.0
|
1.0
|
Omnipath
|
8999859
12400013
15225546
19285992
10353443
12192049
9649448
26496610
12045192
12171929
24958773
8861969
9092549
|
RFC5
|
RFC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
9228079
9751713
28514442
9488738
8692848
33961781
24981860
22939629
26344197
|
RFC5
|
RFC4
|
â—¼ PROTEIN_INTERACTION
|
|
|
1.0
|
1.0
|
HIPPIE
|
9228079
9751713
16189514
9488738
25416956
22939629
28514442
29892012
32296183
26264872
8692848
33961781
24981860
30021884
9092549
26344197
|
RPA3
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
LIG1
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9649448
19223468
22952233
10959839
|
RPA2
|
RPA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA2
|
RPA1
|
â—¼ SHARES_COMPLEX
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA3
|
RPA1
|
â—¼ SHARES_COMPLEX
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA2
|
RPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA3
|
RPA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
XPA
|
RPA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
12527904
19446504
7665601
8972858
7876167
20304803
7565690
9535929
|
RPA2
|
XPA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
11900249
12648680
12947387
15459660
15703371
16697054
17116885
17296725
17386261
17582221
17884153
18677104
19473888
19595721
19596235
19596236
19667075
19686080
19793801
19809470
19847258
20211143
21376743
22101340
22257761
22373527
22615860
22743550
22824526
23085398
24050180
7533895
|
RPA2
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
37.0
|
1.0
|
ACSN
|
11756412
11900249
12648680
12930902
14624239
14726013
15189466
15459660
15703371
16697054
17116885
17296725
17582221
17652783
17884153
18087292
18196958
18584027
18677104
18809224
19258535
1974050
19772495
19793801
19809470
19847258
20211143
20227374
20478261
21282463
21376743
22021614
22743550
23414611
24050180
8264637
8978692
|
RPA2
|
LIG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9649448
19223468
22952233
10959839
|
RPA2
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA2
|
PCNA
|
â—¼ SHARES_COMPLEX
|
|
|
37.0
|
1.0
|
ACSN
|
11756412
11900249
12648680
12930902
14624239
14726013
15189466
15459660
15703371
16697054
17116885
17296725
17582221
17652783
17884153
18087292
18196958
18584027
18677104
18809224
19258535
1974050
19772495
19793801
19809470
19847258
20211143
20227374
20478261
21282463
21376743
22021614
22743550
23414611
24050180
8264637
8978692
|
RPA2
|
RPA3
|
â—¼ SHARES_COMPLEX
|
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
RPA2
|
XPA
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
11900249
12648680
12947387
15459660
15703371
16697054
17116885
17296725
17386261
17582221
17884153
18677104
19473888
19595721
19596235
19596236
19667075
19686080
19793801
19809470
19847258
20211143
21376743
22101340
22257761
22373527
22615860
22743550
22824526
23085398
24050180
7533895
|
RPA2
|
RPA3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
11900249
12648680
14624239
15459660
15703371
16697054
17102137
17116885
17296725
17582221
17884153
18677104
19793801
19809470
19847258
|
XPA
|
RPA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
12527904
19996105
10982866
8972858
20304803
7876167
11081631
7565690
32296183
20670893
9535929
|
LIG1
|
RPA3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9649448
19223468
22952233
10959839
|
MYCN
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
20811720
11107122
10050884
21862876
20145147
19885598
|
TP53
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
17202838
18084622
18945670
11504717
|
TP53
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
10321841
7915517
15358233
12217864
10516009
1705714
8570655
16980608
9707425
15950182
19789303
11313928
1356162
12384701
9858527
12947108
23390122
8524244
9651310
1352831
7909518
11032828
10910968
12485898
10618724
|
TP53
|
HRAS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21552926
9662334
11127813
21552928
|
TP53
|
IGFBP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10101800
23810988
15661074
7566179
15713654
18084616
9525742
20003326
|
TP53
|
TGFB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
12732139
10618379
22264233
23706820
14514686
8183578
14761612
16138117
18593586
23063463
8119773
|
TP53
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12485897
18661553
19763735
|
PPP2CB
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
1848668
17245430
14712210
|
TP53
|
IGFBP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
7566179
17409411
18431400
|
TP53
|
TP73
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11238924
18431400
21508668
9891077
|
AR
|
XPA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20610535
|
PCNA
|
LIG1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
31.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
15871698
16697054
16731526
17088286
17116881
19208614
19364882
1974050
19847258
20056333
20603072
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PCNA
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
PCNA
|
POLD2
|
â—¼ SHARES_COMPLEX
|
|
|
9.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
16697054
1974050
19847258
22021614
23414611
|
PCNA
|
LIG1
|
â—¼ SHARES_COMPLEX
|
|
|
31.0
|
1.0
|
ACSN
|
11756412
14624239
14726013
15703371
15871698
16697054
16731526
17088286
17116881
19208614
19364882
1974050
19847258
20056333
20603072
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PCNA
|
POLD2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
Reactome
|
1671046
8104944
8144677
9081985
1974050
1328683
|
LIG1
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12171929
9649448
28073635
10559261
|
LIG1
|
POLD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
9649448
19223468
22952233
10959839
|
RASA1
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
23.0
|
1.0
|
Omnipath
|
10769036
11389730
23331499
18829532
7628625
9219684
10592173
8663024
16713569
26721396
8360177
8537347
1904555
10394594
2833817
|
SMAD1
|
DVL1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12650946
23331499
16621789
|
CDK8
|
SMAD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
19914168
19914161
|
AR
|
AKT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
20589722
11278645
17896924
18687691
22740037
12621049
12063252
22970326
|
PPP2CB
|
AKT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
15367694
11087733
18039929
19216069
18077353
19556239
19996169
10026142
10995457
18042541
20452955
18559511
8650155
18588945
16680151
11812651
20360384
16406523
|
AKT1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
17470458
18349820
29861848
16210317
21601007
17570479
11404460
22155408
12621049
14555644
11156376
|