Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
RAB5B TBC1D3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18319245 18199687
EGFR ARF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24797263 20029029
HGS GGA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15611048 5217420
TBC1D3 GGA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18319245 18199687
ITGB1 CRKL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0807543105 19168626
ITGB1 CRKL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19168626
HGF GAB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12766170 10871282
GAB1 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 8288622 20308328
PACS1 AP1G1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16977309 5219086
CRK SNX17 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CRK TGOLN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 CYTH2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
HGS EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20308550 0911188107
FGFR1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9480847 16713569
RABEP1 GGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5212386 10747088
TBC1D3 GGA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18319245 18199687
M6PR GGA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11387475 5214102
TBC1D3 GGA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18319245 18199687
MON2 GGA3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6629694 18418388
GGA3 UBA52 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
GGA3 HGS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15611048 5217420
IGF2R GGA3 â—¼   COLOCALIZATION 2.0 0.8 intact 16977309 5219086
GGA3 TGOLN2 â—¼   COLOCALIZATION 2.0 0.8 intact 16977309 5219086
SNX17 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 UBB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TGOLN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
HGS NEDD4 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 12230472 5215741
MET HGS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16713569 8380735
IGF2R TGOLN2 â—¼   COLOCALIZATION 2.0 0.8 intact 16977309 5219086
RNF11 ITCH â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8012720 20676133
UBA52 LAPTM5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
NEDD4 LAPTM5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
PTPN11 MET â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18579758 6731904
UBC NEDD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7104155 19343052
RAB5A TBC1D3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18319245 18199687
RAB5C TBC1D3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18319245 18199687
RABEP1 TBC1D3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18319245 18199687
TBC1D3 RABGEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 18319245 18199687
RNF11 RABGEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
UBA52 RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
UBC RNF11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RNF11 TOLLIP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RNF11 RPS27A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
CRK GRB2 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
RABEP1 RABGEF1 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
GRB2 MET â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
FGFR1 CRK â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 10464310 25241761
ITCH RPS27A â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
NEDD4 NTRK1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 16701206 27445338 21332718 19953087 25921289
GRB2 RET â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
RAB5C ARF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26344197 34079125
RAB5A GGA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 14665628 34079125
GGA1 LRP10 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GGA3 CLH1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11301005
GRB2 CLH1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19380743 31980649
PACS1 MPRI â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11331585 16977309 9695949
PTPN11 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 16729043 5218694
EGFR IGF1R â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17047074 17307140
EGFR PTGDS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31980649 20029029
FGFR2 FGFR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RAB5A GGA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 14665628 34079125
RNF11 UBC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15231748 20676133
IGF2R GGA1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 5214130 11390366
RNF11 GGA3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25195858 15231748
AP1G1 CLTC â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
TOLLIP UBC â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
GAB1 RET â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19914172 32062451 11360177
ALK GRB2 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
BACE1 GGA3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 14567678 26053850
EPHA3 CRK â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11870224 16713569
UBC HGS â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 12750381 5216384
VPS11 VPS18 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
UBB UBC â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
GGA3 UBB â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
GGA2 SYNRG â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10814529 10747088
PACS1 GGA3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16977309
ARF6 CYTH2 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
ARF3 GGA1 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
GGA1 GGA2 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
GGA2 ARF1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10747089 11950392
AP1G1 ARF1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11926829 16189514
GGA3 MPRD â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11387475 11859375
RAB5C MPRI â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 34079125
RAB5A AP1G1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14665628 31980649
GGA2 BACE1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 12135764 14567678 26053850
GGA3 RPS27A â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
PTPN11 EGFR â—¼   DEPHOSPHORYLATION ✅ - 0.86 0.86 Signor 12582165
NEDD4 UBB â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
GGA1 SYNRG â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10814529 17506864 12858163 10747088
CLTC HGS â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
MET CRK â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24728074 24828152
NEDD4 EGFR â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19953087 33762435 29455656
EGFR HGS â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
HGS GGA2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19019082 15611048
NEDD4 UBA52 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
UBB RNF11 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 14755250 33961781
RABGEF1 UBA52 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CLTB CLTC â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
AP1G1 RABEP1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
GAB1 MET â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
GGA1 MPRD â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15044437 11387475
NEDD4 IGF1R â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18632619 12697834 18286479 19165858
CRKL EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
CRK EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
ARF6 GGA3 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
CRKL GAB1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
CYTH2 ARF6 â—¼   GTPASE_REACTION ✅ + 0.88 0.88 Signor 14565977
ARF1 GGA3 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
EGFR MET â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
GGA2 RABEP1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
EGFR ARF6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 34079125 24797263 31980649 20029029
RNF11 GGA1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25195858 15231748 20676133
EGFR CRKL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18271526 24658140 31980649 16729043 23397142 25754235 25402006
GAB1 CRK â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12138161 19380743 16713569 24728074
RABE1 AP1G1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14665628 14973137 12042876 10747088 11387476 12505986
RET CRK â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9393871 10208419 32062451 25241761
RET GRB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 7665556 10995764 15677445 9393871 8183561 32062451 16189514
NTRK1 GRB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10748052 11733534 25921289
EGFR GAB1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
HGS RPS27A â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
FGFR2 GRB2 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
TSG101 UBA52 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
ITCH UBC â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
CLTC GGA1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
GGA1 MPRI â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12060753 20676133 11859375 14567678 15117318 11387475 11859376 11390366
GGA1 RABE1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14665628 16473621 15457209 15143060 17506864 14637142 14636058 10747088 12505986
GGA3 RABE1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16473621 12858162 14665628 12505986
GGA2 RABE1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14665628 28514442 33961781 16473621 14636058 10747088 11387476 12505986
GGA3 MPRI â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16135791 16977309 12060753 11859375 14567678 11387475 11390366 12032548
SYNRG AP1G1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15758025 9653655 12042876 10814529 10747088
EGFR CRK â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10595738 9480911 9642287 24658140 31980649 11956190 16729043 22973453 8875975 25402006 9617486 16273093 12198159
FGFR1 NEDD4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19953087 21765395 25292214
MET GRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9660480 11439336 8662889 19433454 15546961 11063574 7511210 21222362
MET HGF â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18593464 20624990 19433454 22897854 8380735 15167892 16537482 17981115 28205554 17804794 28628118 1846706 18495663 1655405
HGF PTPN11 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17881575 10871282 11323411
RABGEF1 RAB5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11452015 27411398 19759177
GGA1 RABEP1 â—¼   PHYSICAL_INTERACTION 902.0 0.9 STRING 36370105
AP1G1 CLH1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 11387476 11451993 17052248 21411634
GGA1 UBC â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
RABGEF1 RAB5A â—¼   PHYSICAL_INTERACTION ✅ + 0.92 0.92 Signor 11452015
RABGEF1 RAB5A â—¼   GTPASE_REACTION ✅ + 0.92 0.92 Signor 27411398
GGA3 M6PR â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
TSG101 UBB â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
AP1G1 IGF2R â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
EGFR PTPN11 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
RABGEF1 UBB â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
RABGEF1 RPS27A â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
GRB2 PTPN11 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
MET GAB1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 9242692 10871282 10995442 10734310 10913131
GGA2 MPRI â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 31076515 11859375 14567678 11387476 11387475 11390366 29358589
GGA1 SORT1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
RPS27A UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
RPS27A UBC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBB â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
UBA52 UBC â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
GGA1 ARF1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 21198641 15143060 10747089 11950392 12636914
GAB1 CRKL â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 30480076 10753869 23397142 25241761 24728074 10871282
PTPN11 GAB1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 6169284 14701753
PTPN11 GAB1 â—¼   DEPHOSPHORYLATION ✅ 0.96 0.96 mint 20308328 8288622
CLH1 HGS â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 28581508 11532964 16716190 16713569 21411634
RNF11 NEDD4 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 28292929 15231748 11042109 31985874 20676133 19953087
RAB5C RAB5A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 17353931 26496610 28514442 34079125
HGS UBC â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
GGA1 CLH1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 17052248 11301005 17344219 17506864
RABE1 RAB5A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10720461 11718716 26430212 9045618 9524117 15328530 8521472 15378032 34079125
RPS27A TSG101 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
RAB5A RABGEF1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
BACE1 GGA1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
GGA3 RABEP1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
ARF1 CYTH2 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
GGA3 UBC â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
RAB5A RABEP1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
GGA3 ARF1 â—¼   PHYSICAL_INTERACTION 0.98 0.98 HIPPIE 28100775 11301005 10747089 11950392
GGA2 CLH1 â—¼   PHYSICAL_INTERACTION 0.98 0.98 HIPPIE 31076515 11387476 11301005 17344219
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
NEDD4 RPS27A â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
NEDD4 UBC â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CLTA CLTC â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
RABGEF1 UBC â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
VPS11 VPS18 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
TSG101 UBC â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
GGA2 IGF2R â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
HGS TSG101 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RABEP1 RABGEF1 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
RPS27A UBA52 â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
GAB1 GRB2 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GGA3 IGF2R â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
GGA1 IGF2R â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
GAB1 PTPN11 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CYTH2 ARF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9417041 16189514 14565977
CYTH2 ARF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 14654833 17563369 8945478 16189514 10198630 9417041
MET CRKL â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10871282 12138161 11146548 10753869 10618718
CRK CRKL â—¼   PHYSICAL_INTERACTION 84.0 1.0 ACSN 10022831 10086337 10426994 10567412 10811803 10849428 10982827 11062502 11166270 11335727 11353765 11385609 11447289 11449354 11526404 11532940 11579131 11687500 11777939 11907067 11960372 12175651 12393695 12629515 12640133 12670391 13678960 15099563 15111329 15169881 15308668 15501236 15520864 15536084 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16713974 16887996 17086423 17397400 17496910 17673906 17883421 18250477 18287025 18835194 19109239 19414323 19449109 19454690 19909365 20189481 20805416 21149606 21372296 21826665 22064427 22461508 22464172 23087689 23390297 23523669 24217602 24346288 24751819 24795729 25922287 25960930 26201938 26552706 7682895 8551221 8837607 9157999 9314552 9570538 9753319
HGF CRKL â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10871282 12138161 11146548 10753869 10618718
GRB2 CRKL â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 CRKL â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
CRK CRKL â—¼   SHARES_COMPLEX 84.0 1.0 ACSN 10022831 10086337 10426994 10567412 10811803 10849428 10982827 11062502 11166270 11335727 11353765 11385609 11447289 11449354 11526404 11532940 11579131 11687500 11777939 11907067 11960372 12175651 12393695 12629515 12640133 12670391 13678960 15099563 15111329 15169881 15308668 15501236 15520864 15536084 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16713974 16887996 17086423 17397400 17496910 17673906 17883421 18250477 18287025 18835194 19109239 19414323 19449109 19454690 19909365 20189481 20805416 21149606 21372296 21826665 22064427 22461508 22464172 23087689 23390297 23523669 24217602 24346288 24751819 24795729 25922287 25960930 26201938 26552706 7682895 8551221 8837607 9157999 9314552 9570538 9753319
CRK CRKL â—¼   ENZYMATIC_REACTION ✅ 84.0 1.0 ACSN 10022831 10086337 10426994 10567412 10811803 10849428 10982827 11062502 11166270 11335727 11353765 11385609 11447289 11449354 11526404 11532940 11579131 11687500 11777939 11907067 11960372 12175651 12393695 12629515 12640133 12670391 13678960 15099563 15111329 15169881 15308668 15501236 15520864 15536084 15567848 15573129 15574420 16000375 16002046 16076871 16530705 16572188 16582911 16713974 16887996 17086423 17397400 17496910 17673906 17883421 18250477 18287025 18835194 19109239 19414323 19449109 19454690 19909365 20189481 20805416 21149606 21372296 21826665 22064427 22461508 22464172 23087689 23390297 23523669 24217602 24346288 24751819 24795729 25922287 25960930 26201938 26552706 7682895 8551221 8837607 9157999 9314552 9570538 9753319
GAB1 CRKL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10753869 25241761 24728074 31585087 10871282 10592173 23397142
EGFR CRKL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 31980649 23397142 18271526 24658140 25402006 16729043
CRKL GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 10753869 25241761 24728074 31585087 10871282 10592173 23397142
GRB2 GAB1 â—¼   PHYSICAL_INTERACTION 50.0 1.0 ACSN 10086337 10514377 10567412 10648629 10811803 10982827 11062502 11313945 11385609 11447289 11777939 11907067 11940581 12040186 12175651 12419216 12640133 12670391 12782630 14585353 15199124 15534002 15536084 15567848 15574420 15584861 15863030 16102570 16227978 16488589 16582911 16847462 16887996 17496910 17635922 17673906 18287025 19449109 19568798 19615955 20805416 21102635 23523669 24027568 26552706 27111285 7510700 8294866 8551221 9779982
FGFR4 GAB1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 17505008 18757403 21666749 11689702 11739186 18381441 19809159 21160078 14534538 15448205
FGFR2 GAB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11353842 9632781 14534538 9182757
GRB2 GAB1 â—¼   SHARES_COMPLEX 50.0 1.0 ACSN 10086337 10514377 10567412 10648629 10811803 10982827 11062502 11313945 11385609 11447289 11777939 11907067 11940581 12040186 12175651 12419216 12640133 12670391 12782630 14585353 15199124 15534002 15536084 15567848 15574420 15584861 15863030 16102570 16227978 16488589 16582911 16847462 16887996 17496910 17635922 17673906 18287025 19449109 19568798 19615955 20805416 21102635 23523669 24027568 26552706 27111285 7510700 8294866 8551221 9779982
GRB2 GAB1 â—¼   ENZYMATIC_REACTION ✅ 50.0 1.0 ACSN 10086337 10514377 10567412 10648629 10811803 10982827 11062502 11313945 11385609 11447289 11777939 11907067 11940581 12040186 12175651 12419216 12640133 12670391 12782630 14585353 15199124 15534002 15536084 15567848 15574420 15584861 15863030 16102570 16227978 16488589 16582911 16847462 16887996 17496910 17635922 17673906 18287025 19449109 19568798 19615955 20805416 21102635 23523669 24027568 26552706 27111285 7510700 8294866 8551221 9779982
MET GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 10978177 17389395 19901323 10753869 15574420 15212693 10913131 10734310 11896055 20068231 10995442 9890893 16497976 14685170 17016520 18669648 11779868
CRK GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 24728074 20619534 12138161 19380743 11146548 10592173 19350053 16713569 10618718
EGFR GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 19901323 15231819 16497976 25402006 17389395 20068231 23066441 11432805 9658397 19509291 18669648 10978177 10753869 10734310 11896055 18271526 24658140 10648629 11779868 31980649 15212693 9890893 17016520
GRB2 GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 12766170 21706016 9242692 10913131 11445578 22536782 8596638 11027663 10592173 20936779 11960376 15010462 19523899 20005866 19380743 10871282 9804835 14685170 11314042
PTPN11 GAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 72.0 1.0 Omnipath 14701753 18577518 17145710 11453982 12582165 20308328 14665621 8596638 14982882 20473329 11027663 10592173 10788507 9658397 12024020 10068651 24728074 11134009 10194437 12855672 21442024 11323411 11940581 15574420 11278704 10871282 9804835 9632795
ALK PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18320059 19223540 15710330 12522270 12531430 11684012 34301842 8041791 12721296 17483340 32076487
AP1G1 CLTA â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
GRB2 CRK â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
HGF CRK â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 10871282 12138161 11146548 10753869 10618718
GRB2 CRK â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
NTRK1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 7657647 8552402 12446789 7509449
IGF1R CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 12198159 9642287 9480991 9480911 20068231 11956190 8194526 8875975 15522217 17016520
EGFR CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 52.0 1.0 Omnipath 10595738 9480991 16273093 9617486 25402006 17399949 8662907 8875975 21602891 20068231 8194526 12198159 9642287 11956190 24658140 26656091 9480911 31980649 15212693 26473374 16729043 17016520
RET CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9393871 10208419 25241761
EPHA3 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 21071413 16713569 18988627 11870224
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
PTPN11 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 28065597 9756944 7588774 16273093 14560030 9642214 8197172 15618223 12270932 7673163 12582165 10411909 16729043 11223155 12577067
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR HGS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12953068 17016520
FGFR1 GRB2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 17505008 18757403 21666749 11689702 11739186 18381441 19809159 21160078 14534538 15448205
FGFR2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22726438 19735729 26103942 20554525 23420874
FGFR4 GRB2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 17505008 18757403 21666749 11689702 11739186 18381441 19809159 21160078 14534538 15448205
HGS GRB2 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
PTPN11 GRB2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 10358138 11447289 11572860 12138178 12707331 15240681 15699106 15713798 19833085 9751747
GRB2 ITGB1 â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
MET GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 9660480 15546961 22128289 12475979 11063574 7511210 11439336 8662889
NTRK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11733534 10748052
RET GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9393871 16189514 15677445
PTPN11 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 8702859 9361008 16371368 21706016 8041791 11085989 8978300 11432792 15882975 9362449 10212213 11684012 7523381 10592173 16189514 10747947 10973965 9632781 8959326 11602579 12577067 9254654 10080542 15010462 31585087 12531430 8995399 19380743 7522233 9804835 7534299 9824671 9660791
HGS HGF â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 24828152 12686592 12551915 15828871 19109251
HGF MET â—¼   PHYSICAL_INTERACTION 16.0 1.0 ACSN 11290563 12649206 15059978 16212809 17145802 18633355 19631971 20303741 22763439 23402812 23667593 26366398 26819959 27474009 28475121 9242465
HGF MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 57.0 1.0 Omnipath 17145710 22897854 15167892 1655405 20624990 19433454 23331499 17804794 1846706 28475121 22001117 16537482 15218027 27147579 24362531 17667909 16397249 20178463 17981115 28534512 8380735 18495663 14685170
NEDD4 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 21071413 18988627 12697834 19165858
PTPN11 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 28065597 23331499 11779860 7642582 10082579 8895367
RNF11 ITCH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14559117 19131965
RABEP1 RAB5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15328530 17145710 10720461 11452015 11718716 8521472 26430212 9524117 15378032 9045618
RABEP1 RABGEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17450153 26430212 24957337 12505986 9323142 17341663 11452015 10720461