BRCA2
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19369211
0811159106
|
E2F1
|
E2F6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16107498
|
E2F1
|
RBBP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18319725
12909625
|
E2F1
|
RAD51AP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18319725
12909625
|
MANF
|
RAD51AP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
LRRK2
|
RAD51AP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
E2F6
|
RAD51AP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18319725
12909625
|
E2F4
|
RAD51AP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18319725
12909625
|
RAD51B
|
H2BC8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216790
14595808
|
XRCC2
|
RAD51D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
10749867
5212428
|
E2F6
|
RBBP8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
12909625
|
E2F4
|
RBBP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18319725
12909625
|
E2F4
|
XRCC2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17531812
|
E2F4
|
BARD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17531812
|
E2F4
|
BARD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11799067
18319725
|
LRRK2
|
SEM1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
LRRK2
|
E2F4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
29513927
201700444
|
RAD51
|
XRCC2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
20189471
15065660
15123651
19327148
|
RAD51B
|
RAD51D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
BRCA2
|
SEM1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.83
|
0.83
|
mint
|
22293751
8384352
|
BRCA1
|
RBBP8
|
â—¼ UBIQUITINATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
16818604
|
RBBP8
|
BRCA1
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.83
|
0.83
|
Signor
|
24832651
|
BRCA2
|
DMC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
832.0
|
0.83
|
STRING
|
36370105
|
RAD51
|
RAD51C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
BARD1
|
BRCA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
842.0
|
0.84
|
STRING
|
36370105
|
PALB2
|
RAD51
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
26833090
22193777
20332121
28319063
22331464
20871616
24141787
33961781
19584259
28240985
23585894
20871615
29499138
25016020
28398198
16793542
|
RAD51AP1
|
WDR48
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
RAD51
|
RAD51AP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
RAD51AP1
|
USP46
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
RAD51C
|
XRCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
RAD51B
|
XRCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
E2F4
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21102443
16713569
9244350
|
BARD1
|
RAD51
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
14636569
32347575
28976962
25252691
|
ATRX
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
ATRX
|
RAD51
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
23801766
15466868
19671661
12205100
10851248
28976962
32876692
32457312
9321665
12750285
16990250
|
PALB2
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
19369211
25184681
19584259
23038782
29656893
26649820
30337689
28319063
28089683
28398198
22193777
19268590
22331464
34408138
23585894
25016020
19553677
24085845
25652403
|
RAD51
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31270457
31009828
11498787
16713569
19766185
25659039
19369211
25499220
9774970
28319063
17302439
9008167
14636569
28976962
24085845
34408138
29656893
|
BRCA2
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11477095
17664283
16713569
21135251
19369211
9774970
25184681
14636569
24085845
34408138
25652403
14499622
29656893
|
BRCA1
|
RAD51
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16713569
9774970
9008167
|
PALB2
|
BRCA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20332121
19369211
24485656
17200672
24141787
19584259
28240985
23038782
16793542
26833090
26649820
28319063
24835992
30410870
17420451
28398198
22193777
19268590
21466675
22331464
19609323
26990772
23585894
25016020
19553677
28765325
33961781
20871615
22293751
|
BRCA2
|
BARD1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
14636569
17664283
16391231
19176389
|
BRCA2
|
DMC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20729832
17541404
26976601
|
DMC1
|
RAD51
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
33961781
26186194
10562567
17541404
15489243
|
E2F4
|
E2F1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
14576826
10208422
|
E2F1
|
SIAH1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20187294
18627426
|
E2F4
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
14576826
10766737
18319725
|
E2F6
|
RAD51AP1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
12909625
|
PALB2
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
905.0
|
0.9
|
STRING
|
36370105
|
PALB2
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.91
|
0.91
|
mint
|
8329239
22193777
|
PALB2
|
BRCA1
|
â—¼ COLOCALIZATION
|
✅
|
|
0.91
|
0.91
|
mint
|
28319063
|
BRCA1
|
PALB2
|
â—¼ COLOCALIZATION
|
✅
|
|
0.91
|
0.91
|
mint
|
8329239
22193777
|
RAD51C
|
RAD51B
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.91
|
0.91
|
mint
|
34591612
|
DMC1
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
914.0
|
0.91
|
STRING
|
36370105
|
RAD51D
|
XRCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
922.0
|
0.92
|
STRING
|
36370105
|
RAD51C
|
RAD51D
|
â—¼ PHYSICAL_INTERACTION
|
|
|
937.0
|
0.93
|
STRING
|
36370105
|
BRCA1
|
PALB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
940.0
|
0.94
|
STRING
|
36370105
|
RAD51B
|
RAD51C
|
â—¼ PHYSICAL_INTERACTION
|
|
|
949.0
|
0.95
|
STRING
|
36370105
|
BARD1
|
BRCA1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
12431996
17525341
29367421
27977889
19916563
12732733
10477523
20060929
23680151
8944023
22110403
12951069
23086937
14638690
27239795
29355525
9788437
11925436
11257228
24289923
14647430
19176389
15184379
9738006
16403807
29180510
11278247
33589814
15265711
15159397
34408138
16713569
19117993
20681793
16391231
11301010
16489000
23416467
17664283
15569676
29858377
19369211
18493658
29656893
20351172
28398198
12485996
32347575
19766185
14636569
10026184
12700228
31270457
11573085
11526114
24085845
25823446
33961781
32092106
18936166
28514442
20215511
25184681
26490435
28948225
12890688
12438698
28262780
26831064
9342365
10635334
15855157
11504724
11773071
25252691
9798686
26350354
21901007
24695549
12887909
17873885
11498787
27454289
11927591
24981860
25652403
25634209
|
PALB2
|
BRCA2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
19609323
7262167
|
BRCA2
|
RAD51
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
9405383
19875419
23935068
14580352
9774970
15937124
11239456
21076401
10551859
16513631
21601571
25585578
12815053
16793542
11477095
26833090
21670257
26145171
18264088
15713648
9811893
12941707
25282148
20729832
26387543
24835992
18429819
15800651
17515903
21399666
18317453
22116401
11313963
33476590
14636569
15897881
15800615
10373512
9523196
9126738
27941124
17541404
12442171
9560268
20729859
12619154
16914443
28765325
17515904
31113933
28757209
15065660
19303847
28168276
19628690
12606939
24013206
24981860
20871615
15671039
22293751
21789034
|
RAD51
|
BRCA2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
5219969
17541404
|
BRCA1
|
RBBP8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
BRCA2
|
PALB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
981.0
|
0.98
|
STRING
|
36370105
|
USP12
|
WDR48
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
USP1
|
WDR48
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
USP46
|
WDR48
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
BARD1
|
BRCA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
BRCA1
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
36.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19342239
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA1
|
BRCA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
69.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337601
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18448394
18472307
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
19995904
20029420
20081207
20173781
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
XRCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA1
|
E2F1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
24.0
|
1.0
|
ACSN
|
10884389
11877377
12496474
15175241
15220350
15279786
15459660
16581787
17218262
17303408
17660363
17713585
18458534
18590585
18660752
19525936
19793801
20029420
20376879
21060331
21337561
24254977
7575488
7935440
|
BRCA1
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
64.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
E2F1
|
â—¼ SHARES_COMPLEX
|
|
|
24.0
|
1.0
|
ACSN
|
10884389
11877377
12496474
15175241
15220350
15279786
15459660
16581787
17218262
17303408
17660363
17713585
18458534
18590585
18660752
19525936
19793801
20029420
20376879
21060331
21337561
24254977
7575488
7935440
|
BRCA1
|
BARD1
|
â—¼ SHARES_COMPLEX
|
|
|
36.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19342239
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA1
|
BRCA2
|
â—¼ SHARES_COMPLEX
|
|
|
69.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337601
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18448394
18472307
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
19995904
20029420
20081207
20173781
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA1
|
XRCC2
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA1
|
RAD51
|
â—¼ SHARES_COMPLEX
|
|
|
64.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
USP1
|
BRCA1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
16531995
18082604
18082605
18931676
19075014
19217432
19264559
19622404
19686080
23589330
|
BRCA1
|
E2F1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
24.0
|
1.0
|
ACSN
|
10884389
11877377
12496474
15175241
15220350
15279786
15459660
16581787
17218262
17303408
17660363
17713585
18458534
18590585
18660752
19525936
19793801
20029420
20376879
21060331
21337561
24254977
7575488
7935440
|
E2F4
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
20133863
21701264
17531812
17001309
20818429
17106239
23108140
|
E2F6
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
17096023
19466541
12909625
|
E2F1
|
BRCA1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
10660629
23285190
18660752
19466541
17106239
20068145
23108140
|
E2F4
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
9244350
18319725
16713569
12909625
|
BARD1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
99.0
|
1.0
|
Omnipath
|
16403807
16391231
28262780
15159397
25652403
26350354
26490435
14647430
11927591
25184681
16713569
11526114
35203293
9738006
12732733
24289923
11573085
18936166
23086937
24085845
12890688
15855157
24695549
19369211
9798686
11257228
11498787
12700228
11925436
10477523
19176389
23680151
25634209
23416467
34726323
29355525
18369654
14636569
11504724
12951069
19117993
20060929
17873885
14638690
18493658
11278247
15184379
22110403
11301010
11773071
12431996
10635334
20029420
9788437
17664283
21901007
25252691
12485996
10026184
12438698
17525341
16489000
8944023
15265711
12419249
20681793
9342365
27239795
20215511
25823446
19916563
|
E2F1
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
9244350
18660752
18319725
11278247
12697828
16713569
12909625
|
E2F6
|
BRCA1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
18319725
12909625
|
BRCA1
|
RBBP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
21908405
18285836
16713569
15485915
25310973
9738006
17525342
17525340
16843262
24085845
25184681
26387952
18369654
9811458
16818604
20351172
23416467
19442256
10196224
10910365
19452558
11739404
25252691
10764811
25659039
17965729
11689934
|
BRCA1
|
PALB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
26649820
19268590
28089683
28319063
19369211
|
BRCA2
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
64.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA2
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA2
|
XRCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA2
|
XRCC2
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BRCA2
|
RAD51
|
â—¼ SHARES_COMPLEX
|
|
|
64.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11756412
11850621
11877377
11927554
12239151
12551922
12607003
12947387
14624239
14726013
15220350
15459660
15590677
15650050
15703371
16337602
16697054
17303408
17349954
18082604
18082605
18085520
18087292
18584027
18660752
18809224
18931676
19075014
19217432
19264559
19473888
19525936
19622404
19686080
1974050
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
21376743
21574959
22021614
22101340
22505525
22743550
22751496
22771115
23414611
23444773
24050180
9488723
|
BRCA2
|
BARD1
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
USP1
|
BRCA2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
16531995
18082604
18082605
18931676
19075014
19217432
19264559
19622404
19686080
23589330
|
PALB2
|
BRCA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
32.0
|
1.0
|
Omnipath
|
17420451
16793542
26990772
19268590
22293751
17488615
19369211
23585894
24485656
20332121
24141787
26649820
19553677
17200672
26833090
23038782
17200668
15115758
19609323
30410870
19584259
22193777
|
SEM1
|
BRCA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
17145710
26833090
26145171
22293751
24013206
10373512
16205630
16239144
17563742
12228710
|
BRCA2
|
RAD51
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
87.0
|
1.0
|
Omnipath
|
17145710
21601571
15937124
17541404
11313963
16914443
26145171
21670257
18264088
19303847
25585578
12815053
16793542
21789034
25282148
17515904
9126738
20729859
15703751
21076401
15065660
22293751
19875419
12606939
22116401
12619154
23935068
15800615
33476590
15800651
15671039
11477095
16513631
9811893
10551859
20729832
9523196
14636569
17515903
12442171
9405383
26833090
21399666
19628690
9560268
10373512
14580352
|
E2F1
|
RAD51
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
6.0
|
1.0
|
ACSN
|
15279786
17218262
17303408
17660363
18590585
7575488
|
E2F1
|
RAD51
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
16398215
23285190
17218262
12629508
|
E2F6
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
18562691
18319725
9689056
12004135
12909625
|
E2F1
|
RAD51
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15766563
22699938
17218262
|
RAD51B
|
PALB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
19268590
17996710
19369211
17996711
20871616
20871615
28089683
12912992
|
XRCC2
|
PALB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
19268590
17996710
19369211
17996711
20871616
20871615
28089683
12912992
|
RAD51D
|
PALB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
19268590
17996710
19369211
17996711
20871616
20871615
28089683
12912992
|
PALB2
|
RAD51
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
19423707
20871616
24141787
|
SEM1
|
RAD51
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
24076221
22593209
14527420
23509288
24509834
18957201
|
RAD51
|
BARD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
RAD51
|
XRCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
RAD51
|
XRCC2
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
RAD51
|
BARD1
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
USP1
|
RAD51
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
16531995
18082604
18082605
18931676
19075014
19217432
19264559
19622404
19686080
23589330
|
E2F4
|
RAD51
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
11799066
20133863
21701264
17531812
17001309
|
RAD51AP1
|
RAD51
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
17145710
21307306
21903585
16920159
9396801
20871616
17996711
|
XRCC2
|
RAD51AP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
19268590
17996710
19369211
17996711
20871616
20871615
28089683
12912992
|
RAD51D
|
RAD51AP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
19268590
17996710
19369211
17996711
20871616
20871615
28089683
12912992
|
RAD51B
|
RAD51AP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
19268590
17996710
19369211
17996711
20871616
20871615
28089683
12912992
|
RAD51C
|
RAD51AP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
8.0
|
1.0
|
Reactome
|
19268590
17996710
19369211
17996711
20871616
20871615
28089683
12912992
|
E2F6
|
RBBP8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
18319725
12909625
|
WDR48
|
USP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
32951278
18082604
34128540
23116119
23463011
|
BARD1
|
XRCC2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|
BARD1
|
XRCC2
|
â—¼ SHARES_COMPLEX
|
|
|
35.0
|
1.0
|
ACSN
|
10858305
10931916
11571269
11877377
12947387
15220350
15459660
15590677
15650050
16697054
17349954
18660752
18931676
19473888
19525936
19622404
19686080
19759212
19772495
19793801
19793861
19793862
19841479
19847258
20029420
20081207
20376879
20723763
20813759
21060331
21337561
22505525
22751496
22771115
23444773
|