Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
KAT7 POLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
H2AZ1 ACTR6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20473270 7986133
RYBP H2AC11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219279 17070805
H2AC11 RYBP â—¼   COLOCALIZATION 2.0 0.8 intact 5219279 17070805
GRB2 H2AC18 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
KAT7 BARD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
LRIF1 BARD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
CUL4A CHD1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 19661379
INCENP AURKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218018 16239925
RACGAP1 AURKB â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18201571 6166552
AURKB BIRC5 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19357306 0900833106
RYBP BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
KMT2A BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25056311 19208841
CBX8 BMI1 â—¼   COLOCALIZATION 2.0 0.8 intact 17332741 5219708
FOXM1 BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18408007
RAD23B BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16712842 5218673
TP53BP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15970701 21914189
BRD1 ZNF512B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
BRD8 MRGBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
BRD8 MRGBP â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
CBX1 CDYL â—¼   COLOCALIZATION 2.0 0.8 intact 16415788 5218238
CBX8 KAT7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PHC1 CBX8 â—¼   COLOCALIZATION 2.0 0.8 intact 17332741 5219708
PHC2 CBX8 â—¼   COLOCALIZATION 2.0 0.8 intact 17332741 5219708
CBX8 RNF2 â—¼   COLOCALIZATION 2.0 0.8 intact 17332741 5219708
NUSAP1 CDCA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12963707
TPX2 CDCA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12389033
RAD23B CHD1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 19661379
XPC CHD1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 19661379
GRB2 DLD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 EHMT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 EIF4A3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
KMT2A FOXC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16199523
FOXM1 XRCC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20068070 17101782
FOXM1 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17101782
FRG1 MAGOH â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SMCHD1 GNL3L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
GRB2 RACGAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TPX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 RCC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
LRIF1 KAT7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
ZNF512B KDM2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
NPM1 KIF22 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KIF4A KIF22 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15326200 8599929
YWHAB KIF23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
NPM1 KMT2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PHC2 L3MBTL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
MAGOH SDE2 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
XRCC1 MPG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18971944 7294748
NPM1 SUZ12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PHC2 PHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
RACGAP1 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
TERF2 TP53BP1 â—¼   COLOCALIZATION 2.0 0.8 intact 21824286 8202878
TOPBP1 TP53BP1 â—¼   COLOCALIZATION 2.0 0.8 intact 8086392 20871591
VRK1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22621922
ZNF512B VHL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
XPC ZNF512B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
BCORL1 RYBP â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
INCENP KIF22 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CDCA5 TPX2 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
EIF4A3 FRG1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
EIF4A3 SDE2 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
BARD1 AURKB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22350409 19176389
KDM1B NSD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 20670891
CUL4A WDR76 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30655611 17041588
EGFR ACTB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22366308 31980649
BRD3 ATAD5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30554943 31753913
MECP2 BBX â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PCGF1 BMI1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26687479 24981860
BRCA1 PMS2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25184681 29656893
BRCA1 KIFC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26831064 29656893
BRCA1 KIF23 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26831064 29656893
BRD3 CBX4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30554943 31753913
BRD3 RSF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30554943 31753913
BRD3 KDM1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30554943 31753913
BRD3 MECP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30554943 31753913
BRD3 EHMT2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30554943 31753913
WDR76 CBX1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31353912 27248496
MECP2 CENPV â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CHD1L XPC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MECP2 DDX56 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 24981860
DOK2 EGFR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 10508618
PTPN11 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 16729043 5218694
MECP2 SRBD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
XPC PARP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RYBP VRK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 34316702
VPS72 SRCAP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15647280 22939629
CDCA8 KIF22 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
MUS81 TAGLN2 â—¼   KO_UP_REGULATES ✅ + 0.82 0.82 PKG 28854368
CDCA8 INCENP â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
BRD2 BRD3 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
CBX1 EHMT2 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
BRD2 NSD3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30554943 26496610 31753913
SGF29 KIF2C â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
BRCA1 TERF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19797051 25184681 29656893 34112789
VPS72 BRD8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 15647280 31753913
CBX4 PCGF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24981860 27705803 27505670
CHD1L PARP2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19666485 28514442 33961781
JADE3 KAT7 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
LYAR PHF6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22720776 24981860 17353931
XPC RAD23B â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 34591642
CDCA5 INCENP â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
CBX2 PHC2 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
ACTR6 VPS72 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
AURKB SUGT1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28514442 32707033
KAT7 BRD1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 24981860 27142060 27270040 31753913 28514442
CBX8 PHC2 â—¼   COLOCALIZATION ✅ 0.84 0.84 mint 5219708 17332741
KAT7 JADE3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 24981860 27270040 16387653 28514442
AURKB CDCA8 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
BMI1 CBX2 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
EHMT2 CBX1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 24981860 17962312 19706462 15200951 27705803
MORF4L2 MRGBP â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
POLB UHRF1 â—¼   KO_UP_REGULATES ✅ + 0.85 0.85 PKG 28854368
BRCA1 RFC1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25184681 10783165 16713569
EHMT2 MIER1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21258344 18451879
RACGAP1 KIF23 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 8397056 22580824
PRC1 KIF4A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15297875 31586073 23870126
INCENP TPX2 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
CBX4 RNF2 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
PTPN11 EGFR â—¼   DEPHOSPHORYLATION ✅ - 0.86 0.86 Signor 12582165
CCNA2 BRCA1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9244350 25091198 10373534 16713569
TPX2 BRCA1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22110403 25184681 29656893
PHC1 CBX2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 27705803 28514442 22325352
CBX8 CBX4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26496610 22325352 24981860 17332741
PHC2 CBX4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24981860 26496610 21282530 27705803 22325352
BRCA1 TOPBP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BRCA1 TP53BP1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
NPM1 NPM3 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MORF4L2 PALB2 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
PHC1 PHC2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CDCA8 INCENP â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
CBX4 PHC2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
DDX55 DDX56 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 26344197
WDR76 HELLS â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 33288900 31353912 25817432 28514442
BRD8 MORF4L2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PCGF1 RYBP â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
INCENP BIRC5 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5219326 17099693
MRGBP BRD8 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20051959 33961781 24981860 16230350 15647280 12963728 31753913 17573780 28514442
CBX1 LRIF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24981860 16169070 23542155 27705803
BRD8 YEATS4 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
BMI1 RYBP â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
MRGBP YEATS4 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
POLB XRCC1 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
AURKB CDCA8 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
KMT2A MEN1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
SRCAP YEATS4 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
PHC1 BMI1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9009205 33961781 15563468 24981860 19636380 20601937 9199346 9121482 27647897 27705803 28514442 23523425 22325352
CBX4 BMI1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 22078878 24981860 19636380 20601937 18453536 26496610 17332741 9199346 21282530 34316702 27647897 24457600 27705803 12829790 22325352
CBX8 BMI1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 20543829 24981860 19636380 20601937 26496610 17332741 10825164 21282530 34316702 24457600 27705803 22325352
PALB2 BRCA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22331464 19369211 19268590 29656893 25016020 30337689 28319063 28089683 19553677 25652403 22193777 34408138 23585894 23038782 19584259 26649820 24085845 25184681 28398198
PHC1 CBX4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 22078878 24981860 26496610 9199346 21282530 27705803 28514442 22325352
PHC2 CBX8 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24981860 19636380 26496610 17332741 21282530 27705803 25416956 22325352
MAPK7 ELK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10473620
VPS72 YEATS4 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
KIF23 RACGAP1 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
BIRC5 CDCA8 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
CBX4 PHC1 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
CBX8 PHC1 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
PALB2 BRCA1 â—¼   COLOCALIZATION ✅ 0.91 0.91 mint 28319063
BRCA1 PALB2 â—¼   COLOCALIZATION ✅ 0.91 0.91 mint 8329239 22193777
MRGBP VPS72 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
BMI1 CBX4 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
BMI1 PHC1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
RNF2 CBX8 â—¼   COLOCALIZATION ✅ 0.92 0.92 mint 5219708 17332741
PCGF1 RNF2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
CHMP4B CHMP5 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
CBX2 RNF2 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
DNMT3A MPHOSPH8 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
SRCAP VPS72 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
AURKB BIRC5 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CDCA8 BIRC5 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5219326 17099693
BRCA1 PALB2 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
BRD3 BRD2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 28514442 30554943 31753913
RNF2 PCGF1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 24981860
EGFR PTPN11 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CBX8 PHC2 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
BMI1 CBX8 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
GRB2 PTPN11 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
CBX2 RYBP â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 10369680 24981860
POLB MORF4L2 â—¼   KO_UP_REGULATES ✅ + 0.95 0.95 PKG 28854368
RNF2 BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 16710298 5218667
BMI1 CBX8 â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 5219708 17332741
RYBP RNF2 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 24981860
CBX8 RNF2 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
BMI1 PHC2 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
PHC2 BMI1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 24981860 19636380 20601937 25910212 34316702 9121482 16751658 16713569 24457600 27705803 25416956 16189514 22325352 27827373
PHC2 RNF2 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
AURKB INCENP â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 12925766
BRD1 KAT7 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
EIF4A3 UPF3B â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
MAGOH UPF3B â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
BCORL1 PCGF1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
LIG3 XRCC1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
RNASEH2A RNASEH2B â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
RAD23B XPC â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
KAT8 MSL3 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
EIF4A3 MAGOH â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
KAT8 MSL1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MSL1 MSL3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PHC1 RNF2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
ACTR6 SRCAP â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
KIF23 RACGAP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
TOPBP1 TP53BP1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
BARD1 BRCA1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
BMI1 RNF2 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
RNF2 RYBP â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
PARP2 POLB â—¼   PHYSICAL_INTERACTION 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
XRCC1 POLB â—¼   PHYSICAL_INTERACTION 65.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP2 POLB â—¼   SHARES_COMPLEX 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
XRCC1 POLB â—¼   SHARES_COMPLEX 65.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
XRCC1 POLB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 15107487 26186194 8978692 16442856 15520167 11467963 26496610 15367657 25423885 16713569
RNF2 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17636032 15386022
BRCA1 BARD1 â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19342239 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BARD1 UIMC1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BRCA1 BARD1 â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19342239 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BARD1 UIMC1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
TP53BP1 BARD1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
BARD1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 99.0 1.0 Omnipath 16403807 16391231 28262780 15159397 25652403 26350354 26490435 14647430 11927591 25184681 16713569 11526114 35203293 9738006 12732733 24289923 11573085 18936166 23086937 24085845 12890688 15855157 24695549 19369211 9798686 11257228 11498787 12700228 11925436 10477523 19176389 23680151 25634209 23416467 34726323 29355525 18369654 14636569 11504724 12951069 19117993 20060929 17873885 14638690 18493658 11278247 15184379 22110403 11301010 11773071 12431996 10635334 20029420 9788437 17664283 21901007 25252691 12485996 10026184 12438698 17525341 16489000 8944023 15265711 12419249 20681793 9342365 27239795 20215511 25823446 19916563
BIRC5 AURKB â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
AURKB INCENP â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
BIRC5 AURKB â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
AURKB INCENP â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
AURKB INCENP â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
FOXM1 AURKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15817462 15689977 17173139 16314512
AURKB KIF20A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 27939310
AURKB TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28415769
AURKB CKAP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20458174
AURKB KIF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 15630414 26148251 14972678 14960279 17567953 19632184 15064354
AURKB INCENP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 18773538 20619651 26460953 16565220 21554500 19303298 18477699 33067654 27332895 22024163 15316025 24344188 20068231 19357306 22814604 19951914 15249581 25892238 16571674 27512725 11050385 12925766 18669648 15630414 18767990 18691976 17956729 20562864 21051298 32028528 19369195 19995937 20739936 16239925 32356865 20430883
AURKB BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 17145710 23955284 21554500 16291752 18477699 12419797 27332895 19357306 14610074 20807437 17457057 29371939 17099693 11516652 24571573 17681274 21051298 19995937 16769825 20430883
AURKB KIF23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15630414 30728176 16461284 25512391 19203582 15854913 20451386
AURKB RACGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15630414 14744859 19007248 17178910 19555392 18201571 17287340 12689593 15108802 18669648
AURKB KIF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 28992084 31881080 23940115 25512391
BIRC5 INCENP â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
BIRC5 INCENP â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
FOXM1 BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17018632 17173139 16314512 17408638
BMI1 RNF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 16710298 22493164 22902369 20068231 22325352 25355358 17157253 16751658 26496610 16714294 26468281 26151332 12183370 12589020 21772249 25843776 20601937 32296183 21676867 27647897 15563468 27705803 16359901 24457600 19636380
BRCA1 UIMC1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BRCA1 PARP2 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 PARP2 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 UIMC1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
TP53BP1 BRCA1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
BRCA1 XPC â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10367887 10779360 10962562 11877377 12024039 12170778 12496474 12771027 15242590 15459660 15485915 16818604 19004803 19357644 19686080 19788416 19793801 20029420 21060331 21337561 9346961 9892649
BRCA1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20160719 18851829 9000507 21407215
UIMC1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17525341 17525342 17525340 17621610
BRCA1 PALB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 26649820 19268590 28089683 28319063 19369211
SUZ12 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
EHMT2 DNMT3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19308066
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
PTPN11 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 28065597 9756944 7588774 16273093 14560030 9642214 8197172 15618223 12270932 7673163 12582165 10411909 16729043 11223155 12577067
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EME1 MUS81 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
EME1 MUS81 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
PTPN11 GRB2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 10358138 11447289 11572860 12138178 12707331 15240681 15699106 15713798 19833085 9751747
PTPN11 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 8702859 9361008 16371368 21706016 8041791 11085989 8978300 11432792 15882975 9362449 10212213 11684012 7523381 10592173 16189514 10747947 10973965 9632781 8959326 11602579 12577067 9254654 10080542 15010462 31585087 12531430 8995399 19380743 7522233 9804835 7534299 9824671 9660791
KMT2A KAT8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15960975
KIF4A PRC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23870126 15297875 15625105
MEN1 KMT2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17145710 15199122 19075677 16618927 17671196 22936661 22327296 15640349 16997566 20818375 20961854
XRCC1 LIG3 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 17088286 17116881 17884153 18524993 19208614 19362533 19364882 19809470 19847258 20056333 20211143 20227374 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 8264637 8978692
LIG3 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 9705932 20227374 17353931 11163244 26496610 16713569 8264637 11352725 9136882
NPM1 ZC3HC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 22955283 31434245 16009132 12748172
PARG PARP2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 196269035 22469522 22713970 23110147 24684389
XRCC1 PARP2 â—¼   PHYSICAL_INTERACTION 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
XRCC1 PARP2 â—¼   SHARES_COMPLEX 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
TP53BP1 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
TP53BP1 UIMC1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
POLB CHD1L â—¼   KO_DOWN_REGULATES ✅ - -2.33 2.32 PKG 28854368
CBX1 CBX1 â—¼   KO_DOWN_REGULATES ✅ - -2.99 2.98 PKG 28854368
XPC XPC â—¼   KO_DOWN_REGULATES ✅ - -3.23 3.22 PKG 28854368
UNG UNG â—¼   KO_DOWN_REGULATES ✅ - -5.41 5.4 PKG 28854368
PARP2 PARP2 â—¼   KO_DOWN_REGULATES ✅ - -6.68 6.67 PKG 28854368
RECQL5 RECQL5 â—¼   KO_DOWN_REGULATES ✅ - -7.08 7.07 PKG 28854368
POLB POLB â—¼   KO_DOWN_REGULATES ✅ - -7.24 7.23 PKG 28854368
TP53BP1 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -9.54 9.53 PKG 28854368