Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GRB2 AP2M1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
RAD23B BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16712842 5218673
TPX2 BRCA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001199 22110403
TP53BP1 BRCA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15970701 21914189
CBX1 CDYL â—¼   COLOCALIZATION 2.0 0.8 intact 16415788 5218238
XPC CHD1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 19661379
RAD23B CHD1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 19661379
CUL4A CHD1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 19661379
FOXM1 XRCC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20068070 17101782
FOXM1 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17101782
GRB2 H2AC18 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 RCC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 EIF4A3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 EHMT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 RACGAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 TPX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 DLD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PTPN11 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 Reactome 17993263 15031289
LRIF1 KAT7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
CBX8 KAT7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KAT7 POLB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
KAT7 BARD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
KIF4A KIF22 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15326200 8599929
NPM1 KIF22 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
XRCC1 MPG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18971944 7294748
NPM1 KMT2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NPM1 SUZ12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SMCHD1 GNL3L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TOPBP1 TP53BP1 â—¼   COLOCALIZATION 2.0 0.8 intact 8086392 20871591
TERF2 TP53BP1 â—¼   COLOCALIZATION 2.0 0.8 intact 21824286 8202878
VRK1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22621922
TPX2 CDCA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12389033
XPC ZNF512B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
LRIF1 BARD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15383276 5217202
PHC2 CBX8 â—¼   COLOCALIZATION 2.0 0.8 intact 17332741 5219708
PHC1 CBX8 â—¼   COLOCALIZATION 2.0 0.8 intact 17332741 5219708
CBX8 RNF2 â—¼   COLOCALIZATION 2.0 0.8 intact 17332741 5219708
INCENP AURKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218018 16239925
RACGAP1 AURKB â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18201571 6166552
AURKB BIRC5 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19357306 0900833106
RACGAP1 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAB KIF23 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
BRD8 MRGBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
BRD8 MRGBP â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
NUSAP1 CDCA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12963707
KMT2A FOXC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16199523
ZNF512B KDM2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
H2AZ1 ACTR6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20473270 7986133
PHC2 L3MBTL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
PHC2 PHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
BRD1 ZNF512B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
RYBP H2AC11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219279 17070805
H2AC11 RYBP â—¼   COLOCALIZATION 2.0 0.8 intact 5219279 17070805
BCORL1 RYBP â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
EIF4A3 SDE2 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
EIF4A3 FRG1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
ANLN AP2M1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31586073 26496610
BRD3 ATAD5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30554943 31753913
BRCA1 KIF23 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26831064 29656893
BRCA1 KIFC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26831064 29656893
BRCA1 PMS2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25184681 29656893
WDR76 CBX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27248496 31353912
CHD1L XPC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PTPN11 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 16729043 5218694
DOK2 EGFR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 10508618
EGFR ACTB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22366308 31980649
XPC PARP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RYBP VRK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 34316702
CUL4A WDR76 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30655611 17041588
BARD1 AURKB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19176389 22350409
BRD3 RSF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30554943 31753913
MECP2 DDX56 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 24981860
BRD3 EHMT2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30554943 31753913
BRD3 MECP2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30554943 31753913
MECP2 CENPV â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MECP2 BBX â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
MECP2 SRBD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BRD3 CBX4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30554943 31753913
VPS72 SRCAP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 15647280
BRD3 KDM1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30554943 31753913
KDM1B NSD3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20670891 26496610
BRD2 BRD3 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
CBX1 EHMT2 â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
BRCA1 TERF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34112789 25184681 19797051 29656893
CHD1L PARP2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 19666485
XPC RAD23B â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 34591642
WDR76 XPC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 27248496 31353912
SGF29 KIF2C â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
LYAR PHF6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17353931 24981860 22720776
VPS72 BRD8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15647280 33961781 31753913
BRD2 NSD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 30554943 26496610 31753913
CBX4 PCGF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24981860 27705803 27505670
JADE3 KAT7 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
CBX2 PHC2 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
KAT7 JADE3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 27270040 16387653 33961781 24981860
KAT7 BRD1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 27142060 27270040 31753913 33961781 24981860
CBX8 PHC2 â—¼   COLOCALIZATION ✅ 0.84 0.84 mint 5219708 17332741
AURKB SUGT1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 32707033
ACTR6 VPS72 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
EHMT2 CBX1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 27705803 19706462 24981860 15200951 17962312
CBX2 PHC2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21282530 31093962 27705803 22325352 24981860
MORF4L2 MRGBP â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
BRCA1 RFC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 25184681 10783165
RACGAP1 KIF23 â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 8397056 22580824
PRC1 KIF4A â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15297875 23870126 31586073
EHMT2 MIER1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21258344 18451879
PTPN11 EGFR â—¼   DEPHOSPHORYLATION ✅ - 0.86 0.86 Signor 12582165
CBX4 RNF2 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
CCNA2 BRCA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25091198 16713569 9244350 10373534
TPX2 BRCA1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25184681 22110403 29656893
CBX8 CBX4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17332741 22325352 24981860 26496610
MRGBP VPS72 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 15647280 18218781 16230350 33961781 12963728
PHC1 CBX2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 22325352 33961781 24981860
PHC2 CBX4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21282530 27705803 26496610 22325352 24981860
BRCA1 TOPBP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BRCA1 TP53BP1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
NPM1 NPM3 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
MORF4L2 PALB2 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
PHC1 PHC2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CHD1L XRCC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 19661379 33053171 33961781
BARD1 UIMC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19615732 17525341
WDR76 HELLS â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33288900 31353912 25817432 33961781
CBX8 PHC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 27705803 26496610 22325352 33961781 24981860 17332741
CDCA8 INCENP â—¼   PHYSICAL_INTERACTION 879.0 0.88 STRING 36370105
PCGF1 RYBP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16943429 28514442 26687479 27505670 27705803 22325352 33961781 24981860 26186194
DDX55 DDX56 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 26344197
CBX4 PHC2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
BRD8 MORF4L2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PCGF1 RYBP â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
EGFR AP2M1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24797263 20029029 31980649 24189400 23956138 24067654 25754235 31959764
CBX1 LRIF1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27705803 24981860 23542155 16169070
CBX8 PCGF1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21282530 26687479 27505670 27705803 33961781 24981860
INCENP BIRC5 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5219326 17099693
MRGBP BRD8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15647280 17573780 31753913 16230350 33961781 24981860 12963728 20051959
BRD8 YEATS4 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
MRGBP YEATS4 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
POLB XRCC1 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
AURKB CDCA8 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
PALB2 BRCA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19369211 25184681 19584259 23038782 29656893 26649820 30337689 28319063 28089683 28398198 22193777 19268590 22331464 34408138 23585894 25016020 19553677 24085845 25652403
BRCA1 UIMC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21622030 17525340 25184681 17525341 17643121 29656893 19305427 26446986 25252691 26027929 28569838 19766185 19261748 34408138 29499138 19615732 17525342 17621610 31932421 24085845
EME1 MUS81 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19596236 28514442 16189514 25224045 27354282 24733841 25319828 21962513 29738624 19017809 33961781 28575661 14617801 12686547 12721304 17289582 19363487 18413719
KMT2A MEN1 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
PHC2 CBX8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21282530 25416956 19636380 26496610 27705803 22325352 24981860 17332741
AURKB BIRC5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11516652 31315909 19951914 20430883 21554500 23945651 19357306 29568061 21051298 32738097 18477699 17681274 17099693 19995937 16291752 27332895 12419797 31586073 24571573
KAT8 MSL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16227571 20479123 21217699 30224647 33961781 24981860 26186194
MAPK7 ELK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10473620
PHC1 PHC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 16713569 22325352 33961781 15563468 24981860 9121482
PHC1 CBX4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 21282530 22078878 9199346 26496610 27705803 22325352 33961781 24981860
SRCAP YEATS4 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
VPS72 YEATS4 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
PALB2 BRCA1 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 8329239 22193777
PALB2 BRCA1 â—¼   COLOCALIZATION ✅ 0.91 0.91 mint 28319063
BRCA1 PALB2 â—¼   COLOCALIZATION ✅ 0.91 0.91 mint 8329239 22193777
CBX8 PHC1 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
BIRC5 CDCA8 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
CBX4 PHC1 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
MRGBP VPS72 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
RNF2 CBX8 â—¼   COLOCALIZATION ✅ 0.92 0.92 mint 5219708 17332741
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
PCGF1 RNF2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
CHMP4B CHMP5 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
DNMT3A MPHOSPH8 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
CBX2 RNF2 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
SRCAP VPS72 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
AURKB BIRC5 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CDCA8 BIRC5 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5219326 17099693
BRD3 BRD2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 33961781 30554943 31753913
RNF2 PCGF1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 24981860
BRCA1 PALB2 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
EGFR PTPN11 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CBX8 PHC2 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
GRB2 PTPN11 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
CBX2 RYBP â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 10369680 24981860
RYBP RNF2 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 24981860
CBX8 RNF2 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
BARD1 BRCA1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 12431996 17525341 29367421 27977889 19916563 12732733 10477523 20060929 23680151 8944023 22110403 12951069 23086937 14638690 27239795 29355525 9788437 11925436 11257228 24289923 14647430 19176389 15184379 9738006 16403807 29180510 11278247 33589814 15265711 15159397 34408138 16713569 19117993 20681793 16391231 11301010 16489000 23416467 17664283 15569676 29858377 19369211 18493658 29656893 20351172 28398198 12485996 32347575 19766185 14636569 10026184 12700228 31270457 11573085 11526114 24085845 25823446 33961781 32092106 18936166 28514442 20215511 25184681 26490435 28948225 12890688 12438698 28262780 26831064 9342365 10635334 15855157 11504724 11773071 25252691 9798686 26350354 21901007 24695549 12887909 17873885 11498787 27454289 11927591 24981860 25652403 25634209
EGFR GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19254954 7518560 31980649 9416834 7592693 23956138 14679214 10085134 7510700 27059931 21706016 25402006 16799092 16729043 8665853 15657067 24797263 12577067 8810325 7650032 11960376 23799367 25187647 8626525 10026169 19289468 18271526 21278786 7506413 17971399 8940013 20124286 11726515 9886492 10595738 24189400 9020117 19531499 20473329 9020193 8662998 8647858 1322798 8887653 10229072 16273093 25754235 31959764 11370743 16713569 21596750 9685397 24658140 31985874 22973453 11896612 20067773 17242169 19836242 8810340 21278788 30544639 7527043 9050991 11408594 8621459
AURKB INCENP â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 12925766
PHC2 RNF2 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
BRD1 KAT7 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
EIF4A3 UPF3B â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
MAGOH UPF3B â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
BCORL1 PCGF1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
LIG3 XRCC1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
RNASEH2A RNASEH2B â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
RAD23B XPC â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
KAT8 MSL3 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
EIF4A3 MAGOH â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
KAT8 MSL1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PHC1 RNF2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MSL1 MSL3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
ACTR6 SRCAP â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
KIF23 RACGAP1 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
TOPBP1 TP53BP1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
BARD1 BRCA1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
AP2M1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 23956138 31980649 24189400 19351721 20029029 24797263
BRCA1 BARD1 â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19342239 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 UIMC1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BRCA1 PARP2 â—¼   PHYSICAL_INTERACTION 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
BRCA1 UIMC1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BRCA1 BARD1 â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10858305 10931916 11571269 11877377 12947387 15220350 15459660 15590677 15650050 16697054 17349954 18660752 18931676 19342239 19473888 19525936 19622404 19686080 19759212 19772495 19793801 19793861 19793862 19841479 19847258 20029420 20081207 20376879 20723763 20813759 21060331 21337561 22505525 22751496 22771115 23444773
BRCA1 PARP2 â—¼   SHARES_COMPLEX 56.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21060331 21270334 21337561 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
TP53BP1 BRCA1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
BRCA1 XPC â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10367887 10779360 10962562 11877377 12024039 12170778 12496474 12771027 15242590 15459660 15485915 16818604 19004803 19357644 19686080 19788416 19793801 20029420 21060331 21337561 9346961 9892649
BRCA1 SIRT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20160719 18851829 9000507 21407215
UIMC1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17525341 17525342 17525340 17621610
BARD1 BRCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 99.0 1.0 Omnipath 16403807 16391231 28262780 15159397 25652403 26350354 26490435 14647430 11927591 25184681 16713569 11526114 35203293 9738006 12732733 24289923 11573085 18936166 23086937 24085845 12890688 15855157 24695549 19369211 9798686 11257228 11498787 12700228 11925436 10477523 19176389 23680151 25634209 23416467 34726323 29355525 18369654 14636569 11504724 12951069 19117993 20060929 17873885 14638690 18493658 11278247 15184379 22110403 11301010 11773071 12431996 10635334 20029420 9788437 17664283 21901007 25252691 12485996 10026184 12438698 17525341 16489000 8944023 15265711 12419249 20681793 9342365 27239795 20215511 25823446 19916563
BRCA1 PALB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 26649820 19268590 28089683 28319063 19369211
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
PTPN11 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 28065597 9756944 7588774 16273093 14560030 9642214 8197172 15618223 12270932 7673163 12582165 10411909 16729043 11223155 12577067
PRKCB EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 7805884 17570479 12040186 19568798 15567848 14585353
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EME1 MUS81 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
EME1 MUS81 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10882712 12947387 15703371 16612326 16697054 17036055 18157157 18406444 18469862 19473888 19595721 19596235 19596236 19686080 19772495 19805513 19847258 20478261 20655466 22101340
FOXM1 AURKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15817462 15689977 17173139 16314512
FOXM1 BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17018632 17173139 16314512 17408638
PTPN11 GRB2 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 10358138 11447289 11572860 12138178 12707331 15240681 15699106 15713798 19833085 9751747
PTPN11 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 8702859 9361008 16371368 21706016 8041791 11085989 8978300 11432792 15882975 9362449 10212213 11684012 7523381 10592173 16189514 10747947 10973965 9632781 8959326 11602579 12577067 9254654 10080542 15010462 31585087 12531430 8995399 19380743 7522233 9804835 7534299 9824671 9660791
XRCC1 LIG3 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 17088286 17116881 17884153 18524993 19208614 19362533 19364882 19809470 19847258 20056333 20211143 20227374 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 8264637 8978692
XRCC1 LIG3 â—¼   PROTEIN_INTERACTION 34.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 17088286 17116881 17884153 18524993 19208614 19362533 19364882 19809470 19847258 20056333 20211143 20227374 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 8264637 8978692
LIG3 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 9705932 20227374 17353931 11163244 26496610 16713569 8264637 11352725 9136882
MEN1 KMT2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17145710 15199122 19075677 16618927 17671196 22936661 22327296 15640349 16997566 20818375 20961854
NPM1 ZC3HC1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 22955283 31434245 16009132 12748172
PARG PARP2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 196269035 22469522 22713970 23110147 24684389
XRCC1 PARP2 â—¼   PHYSICAL_INTERACTION 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
PARP2 POLB â—¼   PHYSICAL_INTERACTION 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
XRCC1 PARP2 â—¼   SHARES_COMPLEX 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
PARP2 POLB â—¼   SHARES_COMPLEX 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
TP53BP1 UIMC1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 18077395 17525340 18001825 18001824 18006705
TP53BP1 UIMC1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
TP53BP1 BARD1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11042216 11877378 17243194 18087291 19342239 20646866 9748285
AURKB TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28415769
BARD1 UIMC1 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
BARD1 UIMC1 â—¼   SHARES_COMPLEX 10.0 1.0 ACSN 11877377 15459660 16697054 19342239 19772495 19793801 19847258 20029420 21060331 21337561
XRCC1 POLB â—¼   PHYSICAL_INTERACTION 65.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
XRCC1 POLB â—¼   SHARES_COMPLEX 65.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19364882 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
XRCC1 POLB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 15107487 26186194 8978692 16442856 15520167 11467963 26496610 15367657 25423885 16713569
BIRC5 AURKB â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
AURKB INCENP â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
BIRC5 AURKB â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
AURKB INCENP â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
AURKB INCENP â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
AURKB CKAP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20458174
AURKB KIF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 28992084 31881080 23940115 25512391
AURKB KIF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 15630414 26148251 14972678 14960279 17567953 19632184 15064354
AURKB KIF20A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 27939310
AURKB RACGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15630414 14744859 19007248 17178910 19555392 18201571 17287340 12689593 15108802 18669648
AURKB KIF23 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15630414 30728176 16461284 25512391 19203582 15854913 20451386
AURKB BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 17145710 23955284 21554500 16291752 18477699 12419797 27332895 19357306 14610074 20807437 17457057 29371939 17099693 11516652 24571573 17681274 21051298 19995937 16769825 20430883
AURKB INCENP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 18773538 20619651 26460953 16565220 21554500 19303298 18477699 33067654 27332895 22024163 15316025 24344188 20068231 19357306 22814604 19951914 15249581 25892238 16571674 27512725 11050385 12925766 18669648 15630414 18767990 18691976 17956729 20562864 21051298 32028528 19369195 19995937 20739936 16239925 32356865 20430883
BIRC5 INCENP â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
BIRC5 INCENP â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
KIF4A PRC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23870126 15297875 15625105
KMT2A KAT8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15960975
SUZ12 DNMT3A â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 16357870 24074865 23326524 12435631 22466170
EHMT2 DNMT3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19308066
RNF2 RYBP â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
RNF2 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17636032 15386022