Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ATM L3MBTL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29581593 31225475
CBX5 MBD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CBX5 YY1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YY1 CBX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19566924
E2F1 CBX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12909625
MAX CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11313917 18393360
EZH2 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18980972 21765901
L3MBTL3 E2F1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0610279104 17517653
E2F1 E2F6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16107498
HDAC1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17980157 18319725
E2F1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9368006
E2F1 RBBP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 12909625
E2F1 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19303924
E2F1 AURKB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 15033491
HIF1A EGLN3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218395 16511565
EPAS1 EGLN3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20061373 15156561
EGLN3 HIF1A â—¼   HYDROXYLATION ✅ 2.0 0.8 intact 5217229 15474027
NFKB1 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12456660 16135789
EP300 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 CDKN2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22000024 19419955
EP300 RELA â—¼   ACETYLATION ✅ 2.0 0.8 intact 5214468 11533489
EP300 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16374512 11433299
IDH1 DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
RELA OGT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6166964 17882263
RBBP7 AEBP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23110252 15225548
YY1 TP53BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22951020
RELA TP53BP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8910340 8524315
CBX6 USP7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7998286 20601937
USP7 CBX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7998286 20601937
USP7 CBX7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7998286 20601937
USP7 SKP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19680264
YY1 EPAS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19483472
YY1 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24369345
CBX7 CBX8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17332741 5219708
PHC2 CBX8 â—¼   COLOCALIZATION 2.0 0.8 intact 17332741 5219708
PHC1 CBX8 â—¼   COLOCALIZATION 2.0 0.8 intact 17332741 5219708
CBX8 BMI1 â—¼   COLOCALIZATION 2.0 0.8 intact 17332741 5219708
CBX8 RNF2 â—¼   COLOCALIZATION 2.0 0.8 intact 17332741 5219708
RELA CDK6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18504428
KLF15 FOS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
KDM2A SMAD7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
FOS SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15579469
KDM2A SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
MTF2 SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD3 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10199400 11427533
NFKB1 HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
RELA HDAC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11931769 5215238
RELA HDAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23027620
RB1 HDAC1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
RB1 HDAC2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5211419 10228159
MAX MGA â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
RELA EPAS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20495570
RELA KDM2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20080798
FOS RELA â—¼   PROXIMITY 2.0 0.8 intact 18172215 0705181105
RELA FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 10488148
ESR1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23403292 24998469
NFKB1 CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12456660 16135789
HIF1A CREBBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17382325 5219810
HIF1A EGLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218395 16511565
EGLN1 HIF1A â—¼   ENZYMATIC_REACTION ✅ 0.8 0.8 mint 7987706 20840591
HIF1A KDM2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32938217
HIF1A KDM2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32938217
EGLN1 HIF1A â—¼   HYDROXYLATION ✅ 2.0 0.8 intact 5217229 15474027
HIF1A EGLN2 â—¼   HYDROXYLATION ✅ 2.0 0.8 intact 5217229 15474027
HIF1A EGLN1 â—¼   HYDROXYLATION ✅ 0.8 0.8 mint 5217229 15474027
YY2 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15087442
RB1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 1909121 7680889
FOS PDHA1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8476854
FOS NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20188076
NFKB1 KDM2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20080798
CBX4 BMI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17332741 5219708
RYBP BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
EZH2 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21465172 19351856
ESR1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 16582100
ESR1 EGLN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489 11850811
EZH2 PC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23624931 21465172
EZH2 FBXO32 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21546904 24213577
EZH2 CDKN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20574448
EPAS1 KDM2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32938217
KDM2B RNF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24457600 17296600
ZNF512B KDM2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
EPAS1 KDM2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 32938217
RNF2 PCGF6 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 24981860
BCOR RNF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24457600 17296600
EGLN2 EPAS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12788921 15474027
E2F6 RBBP4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18319725 12909625
PHC2 L3MBTL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
PHC2 SFMBT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
PHC2 PHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
YAF2 RING1 â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 8153045 21516116
SFMBT1 PHC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
E2F6 PCGF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11171983 5213507
RYBP E2F6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 11171983 5213507
E2F6 REEP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215370 12004135
E2F6 L3MBTL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 0610279104 17517653
ASXL1 CDKN2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 26470845
RNF2 SCML2 â—¼   PHYSICAL_INTERACTION 802.0 0.8 STRING 36370105
PHC1 SCMH1 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
PCGF1 USP7 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
BCORL1 RYBP â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
BAP1 FOXK1 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
HIST3H3 PHF19 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
L3MBTL2 RNF2 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
NFKB1 EP300 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 11739381 23811396 14662860 12471036 20065107 22013068 12960163
EP300 HDAC1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 14968110 30110629 22778253 16787918 33742100 18722353 22731250
CBX7 HDAC2 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 19706751 22214847
EPAS1 EGLN2 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 23275444 17353276 15474027
CREBBP FGFR1 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
CBX4 PCGF2 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
RYBP TFDP1 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
JARID2 PHF19 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
PHF1 RBBP7 â—¼   PHYSICAL_INTERACTION 815.0 0.81 STRING 36370105
BCORL1 SKP1 â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
CBX8 CBX3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 24981860
CBX3 BCOR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 24981860
CBX3 TFDP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
CBX5 SUZ12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27634302 20562864
CBX5 BAP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27107012 34591877
CBX5 AURKB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20231385 20562864
EPAS1 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23275444 15261140 22807441 25689462
DCAF7 EP300 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35016035 31753913
PHF19 PHF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
CBX8 E2F6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26496610
CBX8 SKP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
CBX8 FBRS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
TFDP1 WDR5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
HDAC1 RING1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26496610
YAF2 HDAC2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22325352 27705803
SKP1 ESR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31527615 23770852
FOS ESR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17317669 25303530
PCGF6 BMI1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 12167161
PCGF1 BMI1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 26687479
BMI1 PCGF3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22493164 24981860
ESR1 SUZ12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31527615 26389696
ESR1 BCOR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26487511 31527615
CBX6 SCML1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
PHF19 TEX10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PCGF5 PCGF1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22493164 24981860
PCGF1 PCGF6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22493164 24981860
CGB2 KDM2A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LCOR RBBP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
PHF19 RBBP4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23104054 27705803
RBBP4 RYBP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30217970 34316702
PHC2 SCML1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22325352 27705803
PHC2 PCGF3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25416956 24981860
PHC2 PCGF5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25416956 24981860
CBX4 PCGF5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
CBX4 FBRS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
RING1 PCGF5 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 24981860
AUTS2 RING1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 25519132 27705803
DCAF7 RING1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 27705803
TFDP1 RING1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
RING1 FBRS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
PCGF3 PHC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 32296183 24981860
DCAF7 BCOR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 33722704
PHC3 SCML1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22325352 27705803
E2F6 PCGF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 11171983 24981860
PCGF2 SCML1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 22325352
LCOR PHF19 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
LCOR MTF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
LCOR EZH1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 27705803
CBX7 HIST2H3C â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
CBX2 HIST2H3C â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
HIST2H3C TP53BP1 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
L3MBTL2 MGA â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
CBX7 PCGF2 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
CBX6 HIST2H3C â—¼   PHYSICAL_INTERACTION 828.0 0.82 STRING 36370105
MAX CBX3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29028833 24981860 27705803
CBX3 WDR5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24981860 33022573 27705803
CD44 FGFR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 15597342
KLF15 EP300 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 35140242 35016035 23999430
HDAC1 FOXK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26496610
RBBP7 FOXK1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
LCOR PHF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 27705803 24981860
PHF1 RBBP7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 18285464 18385154 27705803 29846670 33961781 24981860
PHF1 RBBP4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29846670 24981860 23273982 27705803
PHF1 EZH1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 23273982 27705803 24981860
EZH1 RBBP7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 27705803 24981860
PHF19 RBBP7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23104054 27705803 33961781
CBX7 BCOR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
MAX WDR5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24981860 27705803 20946988
YAF2 WDR5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27705803 22325352 33961781 24981860 26186194
RING1 WDR5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22325352 24981860 33022573 27705803
HDAC1 E2F6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26496610
MAX RING1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29028833 24981860 27705803
MAX E2F6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27705803 33961781 25609649 24981860 29028833
MAX PCGF6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27705803 22325352 33961781 25609649 24981860 29028833 20946988
MAX RYBP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29028833 33961781 27705803
MAX YAF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29028833 33961781 27705803
RYBP SKP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22325352 24981860 27705803
YAF2 SKP1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22325352 24981860 27705803
SKP1 RING1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 27705803 24981860
CREBBP HIST2H3C â—¼   PHYSICAL_INTERACTION 829.0 0.83 STRING 36370105
KDM2B FOS â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 35140242 26725323
ASXL1 HCFC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27705803 32683582 32669118 26416890
ASXL2 HCFC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27705803 32669118 26416890
AEBP2 EZH1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 27705803 24981860
PHC3 CBX2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22325352 24981860 27705803
PHC3 CBX6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22325352 33961781 27705803 24981860
CBX6 PHC2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21282530 27705803 22325352 33961781 24981860
E2F6 EZH2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16565076 15536069
EZH2 MTF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27705803 20123894 33961781 24981860 33849069 27634302 24457600
CBX4 PCGF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24981860 27705803 27505670
MTF2 RBBP4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 27705803 24981860
BAP1 HCFC2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 34591877 27705803
PHC2 SCMH1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22325352 24981860 16713569 16169070
PCGF3 CBX4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22325352 24981860 27705803
CBX4 BCOR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24981860 27705803 27505670
PHC3 RING1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22325352 24981860 27705803
PCGF3 FBRS â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22325352 24981860 27173435 27705803
PCGF3 AUTS2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22325352 25519132 27705803
PHC1 PHC3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 22325352 33961781 24981860
DCAF7 PCGF5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 27705803 24981860
PCGF2 SCMH1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 22325352 33961781 24981860
EZH1 MTF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 27705803 24981860
FOXK2 ASXL2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27705803 32669118 25609649 26416890 24748658
ASXL2 MBD5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
YAF2 RYBP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 24981860
CBX3 HIST2H3C â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CBX5 HIST2H3C â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
SKP1 UBE2D2 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
CBX3 PCGF6 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
CBX2 PHC2 â—¼   PHYSICAL_INTERACTION 834.0 0.83 STRING 36370105
HIST2H3C WDR5 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
PCGF2 RYBP â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
HCFC1 E2F1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17612494 20622854
EP300 FOS â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 19064921 21937452 11287611 24069158
CBX8 PHC2 â—¼   COLOCALIZATION ✅ 0.84 0.84 mint 5219708 17332741
BCOR HDAC1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16713569 23658227 10898795
CBX6 BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 24981860
ESR1 EZH2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 17502350
SUZ12 AEBP2 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 24981860
CBX6 PCGF3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21282530 24981860
ASXL3 BAP1 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
PHC1 SCMH1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28514442 10653359 22325352 33961781 24981860
EZH1 JARID2 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
CBX7 RING1 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CBX7 PHC3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
CS MDH2 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
DLAT OGDH â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
BMI1 CBX2 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
IDH1 IDH3G â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
IDH1 IDH3B â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
CS SUCLG1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CBX2 RING1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
PHF1 EZH2 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
ESR1 RBBP7 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 18577416 23403292 21182205 31527615
RBBP7 FOXK2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 33961781 26186194 27773593
PCGF3 CBX7 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 21282530 33961781 26186194
CBX7 PCGF1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 21282530 33961781 26186194
HDAC2 HIF1A â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 25241761 11641274
MAX TFDP1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 27705803 33961781 25609649 24981860 29028833
BCOR SKP1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16943429 26687479 27505670 27705803 33961781 24981860
BMI1 EED â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23238014 24457600
CBX2 PHC2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 21282530 31093962 27705803 22325352 24981860
RING1 PCGF1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
RNF2 PCGF5 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24981860
CDK6 CDKN1B â—¼   PHOSPHORYLATION ✅ - 0.85 0.85 Signor 16160006
EP300 FOS â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
PCGF6 WDR5 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
CS IDH3G â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
PCGF2 SCMH1 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
SDHB SUCLG1 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
CBX6 PHC3 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
ASXL2 MBD6 â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
E2F1 EP300 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
RING1 E2F1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11583618 27705803
EPAS1 EGLN3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17684156 17353276 15474027 23275444
EP300 SMAD3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9679056 15824515 15688032 16109717 15345715 20564330 9843571 15133024 10497242 17469184 15623506 10575014 15588252 18055455 16876108 21567395 11134049 12743039 11058129
DCAF7 FOXK1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 35016035 27173435
SMAD3 NEDD4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19953087 32296183 15496141 21685363
WDR5 HDAC2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 27705803
FOXK2 HDAC2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25609649 27773593
FOXK2 HCFC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25451922 25609649 24748658
IDH2 IDH3B â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
PCGF3 RING1 â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
IDH2 IDH3G â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
PHC3 SCMH1 â—¼   PHYSICAL_INTERACTION 860.0 0.86 STRING 36370105
HDAC1 YY1 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
HIST2H3C HIST3H3 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
AURKB HIST3H3 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
CBX4 PHC3 â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
CBX4 RNF2 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
RYBP CBX3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34316702 27705803 22325352 33961781 24981860
BAP1 CBX3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32509391 19615732 34591877 29686263
CBX3 YAF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22325352 27705803 24981860 12004135
CBX3 RING1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27705803 33961781 12004135 24981860
ASXL1 FOXK1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27705803 32683582 32669118 26416890
ASXL2 FOXK1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 32669118 26186194 26416890
PHF1 EED â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18285464 27705803 26496610 29846670 33961781 24981860 23273982
PHF1 SUZ12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 18285464 18385154 27705803 29846670 33961781 23273982 24981860 27634302 24457600
EZH2 RBBP7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 26496610 33961781 24981860 26186194 27634302 24457600
SUZ12 RBBP7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 33961781 35016035 26186194 24981860 12435631 27634302 24457600 31281901 20075857
BAP1 RBBP7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32509391 19615732 34591877 29686263
AEBP2 RBBP7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26186194 27705803
RBBP7 EED â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 26496610 33961781 24981860 26186194 12435631
RBBP7 MTF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 33961781 24981860 26186194
PHC3 CBX8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22325352 27705803 24981860 26496610
CBX8 CBX4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17332741 22325352 24981860 26496610
PHC1 CBX7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 27705803 24981860
CBX7 PHC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21282530 19636380 27705803 33961781 24981860 26186194
CBX7 PHC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 33961781 24981860 26186194
PCGF6 WDR5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 22325352 33961781 24981860 26186194
HDAC1 WDR5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 23752268 27705803 33961781 26186194 33022573 22689669
WDR5 E2F6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15960975 28514442 27705803 33961781 24981860 26186194
SMAD3 MAX â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16189514 25241761 12551947
SUZ12 HDAC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24457600 26344197 22439931
FOXK2 HDAC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27773593 24748658
PCGF6 HDAC1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22325352 33961781 27705803
HDAC1 TFDP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 27705803
PCGF6 HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 27705803
EZH2 HDAC2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10581039 24981860 21685935 26344197
HDAC2 SUZ12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22939629 24981860 26344197 20075857
PCGF2 BMI1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 20601937 33961781 24981860
BMI1 PHC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 34316702 20601937 19636380 27705803 22325352 33961781 24981860 24457600
BMI1 CBX2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21282530 34316702 20601937 19636380 27705803 22325352 33961781 24981860 24457600
ESR1 FOXK2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31527615 25740706
PHF19 EED â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 23104054 27705803 26496610 33961781 24981860 21143197
LCOR EED â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24981860 26496610 27705803
EED MTF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27705803 24981860 26496610
EZH2 AEBP2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 29348366 26496610 27705803 28068325 33961781 24981860 26186194 27634302 24457600 31281901
PHC1 CBX2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 22325352 33961781 24981860
PHC1 CBX6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 22325352 33961781 24981860
DCAF7 CBX6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 27705803
LCOR EZH2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24981860 26496610 27705803
PHF19 EZH2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 23104054 27705803 33961781 24981860 27634302 21143197 24457600
PCGF1 YAF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27505670 27705803 22325352 33961781 24981860
PHC2 CBX4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21282530 27705803 26496610 22325352 24981860
PCGF2 CBX4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21282530 20601937 19636380 27705803 22325352 33961781 24981860
CBX4 PCGF6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21282530 33961781 27705803
CBX4 PHC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21282530 27705803 26496610 22325352 24981860
DCAF7 PCGF3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 27705803 24981860
PCGF3 YAF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 22325352 33961781 24981860
PCGF3 BCOR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23523425 25416956 24981860 27705803
AUTS2 PCGF6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 25519132 33961781 27705803
PCGF6 TFDP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 22325352 33961781 24981860
PCGF6 FBRS â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 27705803 24981860
PCGF6 YAF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 22325352 33961781 24981860
YAF2 BCOR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 26687479 27505670 26496610 27705803 22325352 33961781 24981860
BCOR PCGF5 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 25416956 24981860 27705803
PCGF2 PHC3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 20601937 19636380 27705803 22325352 33961781 24981860
PHC1 SCML1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22325352 33961781 27705803
PCGF5 YAF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 22325352 33961781 24981860 26186194 27684187
PCGF5 FBRS â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 22325352 33961781 24981860 26186194
PCGF2 RYBP â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 22325352 33961781 24981860 26186194
PCGF2 YAF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 20601937 27705803 22325352 33961781 24981860
AUTS2 DCAF7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 25519132 33961781 35016035
YAF2 DCAF7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 27705803
DCAF7 FBRS â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 35016035 27705803
SUZ12 PHF19 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 23104054 27705803 33961781 24981860 27634302 24457600
PHF19 EZH1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 27705803 24981860
YAF2 E2F6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 22325352 33961781 24981860
MTF2 SUZ12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 20123894 33961781 24981860 24457600
FOXK2 ASXL1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 27705803 32669118 25609649 32683582 26416890
RYBP TFDP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 22325352 33961781 26186194
AUTS2 YAF2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 25519132 33961781 27705803
YAF2 FBRS â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 22325352 33961781 24981860
SUZ12 LCOR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27705803 33961781 35016035 24981860
YAF2 TFDP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22325352 33961781 27705803
CBX3 CBX5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AUTS2 PCGF5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
SDHA SDHC â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
FBRS PCGF5 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
E2F6 RYBP â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EP300 NFKB1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BAP1 HCFC1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BCOR KDM2B â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ASXL1 BAP1 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BAP1 FOXK2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
E2F6 PCGF6 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ESR1 HDAC1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
MGA PCGF6 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
RNF2 UBE2D3 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CSNK2B PCGF5 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CREBBP ESR1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EED MTF2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PHC1 PHC2 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
MGA RYBP â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
E2F1 HDAC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10734134 9468140 17980157 26468294 9468139
HIF1A EGLN3 â—¼   HYDROXYLATION ✅ 0.88 0.88 mint 5217229 15474027
CBX8 PCGF3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21282530 24981860 27705803
CBX8 PCGF5 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21282530 27705803 24981860 26496610
CBX8 KDM2B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24981860 27705803
CBX8 PCGF6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 21282530 27705803 33961781 24981860
CBX8 PHC1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 27705803 26496610 22325352 33961781 24981860 17332741
CBX7 PCGF6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 21282530 19636380 27705803 33961781 26186194
FOS SMAD3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21829441 9732876
PCGF1 SKP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16943429 26687479 27505670 32628469 27705803 22325352 33961781 24981860
EGLN2 HIF1A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11292861 26644182 11292862 16511565 15474027 16155211 17353276 18264140
E2F6 BMI1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11171983 16189514 24981860
HCFC1 HCFC2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781 24981860 15199122
IDH3B IDH3G â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 16189514 16713569 31536960 10677231 33961781 26186194
PCGF2 CBX2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 31093962 20601937 19636380 27705803 22325352 33961781 24981860
CBX6 PCGF2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 21282530 27705803 33961781 24981860
CBX6 RING1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21282530 27705803 22325352 33961781 24981860
PCGF1 RYBP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16943429 28514442 26687479 27505670 27705803 22325352 33961781 24981860 26186194
RING1 KDM2B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24981860 27705803
BCOR RING1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16943429 26687479 27505670 27705803 26496610 24981860
E2F6 RNF2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
CBX4 PHC2 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
BCOR RING1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
MGA WDR5 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
BCOR RNF2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
E2F6 MGA â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
E2F6 L3MBTL2 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
HDAC2 RELA â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
L3MBTL2 RYBP â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
EP300 YY1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
ATM H2AFX â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
BMI1 UBE2D3 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
RNF2 WDR5 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PCGF1 RYBP â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
RING1 RNF2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
PCGF5 RYBP â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CBX7 PHC1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
CREBBP SMAD3 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
IDH2 IDH3A â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
FBRS RYBP â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
BCOR BCL6 â—¼   PHYSICAL_INTERACTION ✅ + 0.88 0.88 Signor 10898795
PCGF3 RYBP â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
PCGF5 YAF2 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
BCL6 BCOR â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
IDH3A MDH2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
BCOR RYBP â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HDAC1 BCL6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15454082 9627120 9753732 16147992 10611298
CBX3 PCGF6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 27705803 12004135 22325352 33961781 24981860
CBX3 E2F6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27705803 12004135 33961781 24981860 34079125
CBX5 RBBP4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27705803 24981860 21888893 15306854 15882967 20562864
EZH2 PHF1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 18285464 18385154 26496610 27705803 29846670 28068325 33961781 23273982 24981860 11571280 23142980 27634302 24457600
RB1 RBBP7 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
HDAC2 YY1 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
CBX8 PCGF1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21282530 26687479 27505670 27705803 33961781 24981860
CBX8 BCOR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24981860 27705803 27505670
CDK6 CDKN2B â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
CBX7 PCGF2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 21282530 20601937 33664452 19636380 27705803 33961781
RYBP WDR5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 27705803 22325352 33961781 26186194
HCFC2 WDR5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 27705803 33961781 24981860 26186194 15199122
ASXL2 MBD6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 27705803 33961781 26186194
HIF1A SMAD3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12228247 28471448 11486006 14741200
EED HDAC2 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
BMI1 RYBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 20601937 27705803 22325352 33961781 24981860 26186194 24457600
BMI1 YAF2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 20601937 27705803 22325352 33961781 24981860 24457600
BMI1 CBX6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21282530 34316702 20601937 27705803 22325352 33961781 24981860
AEBP2 RBBP4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15225548 29348366 27705803 33961781 24981860
PCGF1 KDM2B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16943429 26687479 25533466 27505670 23395003 29985131 32628469 27705803 22325352 33961781 29502955 24981860
RYBP KDM2B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 23395003 27705803 22325352 33961781 24981860 26186194
EPAS1 EGLN1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19208626 23275444 19147576 31763849 16407130 15474027 30487161 17353276
EZH1 RBBP4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 27705803 24981860
PHC1 RING1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 9199346 27705803 22325352 33961781 24981860
PCGF5 RING1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 22493164 27705803 22325352 33961781 24981860 26186194
YAF2 RING1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 25416956 27705803 22325352 33961781 24981860 21516116 27684187
RING1 PCGF6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 22493164 12167161 27705803 22325352 33961781 24981860
RING1 PCGF3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32296183 22493164 27705803 22325352 24981860
PCGF3 RYBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 27705803 22325352 33961781 24981860 26186194
PCGF6 E2F6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 16189514 11171983 27705803 22325352 33961781 24981860 26186194
PCGF6 RYBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 27705803 22325352 33961781 24981860 26186194
BCOR RYBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16943429 28514442 26687479 27505670 34316702 27705803 22325352 33961781 24981860 26186194
PCGF2 PHC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 20601937 33664452 19636380 27705803 22325352 33961781 24981860 23523425
PCGF5 RYBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 27705803 22325352 33961781 24981860 26186194
PCGF5 AUTS2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 27705803 22325352 25519132 33961781 26186194
DCAF7 RYBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 27705803 33961781 24981860
AUTS2 RYBP â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
RYBP FBRS â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34316702 27705803 22325352 33961781 24981860 26186194
RYBP AUTS2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 27705803 25519132 33961781 26186194
CBX8 PHC3 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
L3MBTL2 PCGF6 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
RBBP4 RBBP7 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
FBRSL1 RYBP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CREBBP RELA â—¼   ACETYLATION ✅ + 0.89 0.89 Signor 16382138
BMI1 RYBP â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CDK6 CDKN1B â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
HDAC1 NFKB1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
PHC3 RING1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
HDAC1 RELA â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
JARID2 RBBP4 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
EZH2 HDAC2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
BMI1 CBX6 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
BCORL1 KDM2B â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
SDHB SDHC â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
CBX8 PCGF2 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
BMI1 CBX7 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
BMI1 PHC3 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
EZH1 MTF2 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
E2F1 ATM â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22832221 23993922 12527885
ATM TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15838517 15494392 15140942
BCOR BCL6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23911289 16713569 15004558 33468080 26496610 18280243 10898795 20807888
EP300 BCL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17828269 12402037
CBX5 CBX3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314413 11336697 16713569 20850016 27705803 20231385 33961781 21888893 24981860 15306854 34079125 20562864 19498464
E2F1 CBX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12629508
CDKN1B TFDP1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
HIF1A CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19342889 20138114 19940121
ESR1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17163418 17681750
HCFC1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17612494 19763085 23629655
E2F1 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23796898 17360938 16582100
E2F1 FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19303924
E2F1 RELA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24755270
EP300 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10753885 15123636 15126619
E2F1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19276347 21625432
HIF1A EGLN3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25416956 18402654 18063574 16511565 15474027 31239290 24015760 17069766 17353276 16155211 30067985 26972000 23345396 15721254 18264140
EP300 ESR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19887647 11782371 12738788 25728767 11867769 12479814 23065768 15308690 20388208 14761960 22227247 8799122 20348541 23403292 12714702 11581164 16713569 19838210 18765668 16645043 30418174 12574227
YY1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
BAP1 FOXK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25451922 20805357 34591877 27705803 33961781 25609649 19815555 32509391 19615732
MPG ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17129768 14761960
FGFR1 NEDD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 19953087 25292214 21765395
PHF1 SUZ12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24457600 18285464
RBBP4 RBBP7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17255935 27705803 22863883 33961781 24981860 26186194 15451426 22939629 26344197
YY1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9238849 21852380
YY1 HCFC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 8661027 23000143
HDAC1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18634613 11486036 11940654
PCGF2 CBX8 â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 7998286 20601937
PCGF2 CBX8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 21282530 17936708 20601937 33664452 19636380 27705803 22325352 33961781 24981860
PHC2 CBX8 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21282530 25416956 19636380 26496610 27705803 22325352 24981860 17332741
CBX8 BMI1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21282530 34316702 20543829 10825164 20601937 19636380 26496610 27705803 22325352 33961781 24981860 17332741 24457600
CDK6 TFDP1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11884610 7797074 9144196
BMI1 CBX7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 21282530 20543829 20601937 19636380 27705803 33961781 24981860 26186194 17332741
CBX7 RING1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21282530 14647293 19636380 27705803 33961781
HCFC1 WDR5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15960975 27705803 24981860 20305087 22939629 12670868 15199122
SDHA CSNK2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
HDAC1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11306568 19049980 10575014
HIF1A HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17273746 11641274 16511565 21148070 24015760
ESR1 HDAC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17312152 31527615 24051437 33731348 14722073 21182205 15557281 18451880 14506733 15140878
BCOR HDAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 10898795
SKP1 KDM2A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 30033217 17463251 27705803 33961781 24981860 15070733
SDHD SDHA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23747254 25564869 23564345
SDHD SDHC â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23747254 25564869 23564345
FGFR1 CREBBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 25241761 15929978
CREBBP NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12789342 16835236
HIF1A EGLN1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24681946 20724477 31763849 15721254 20812988 25974097 16407130 27563096 26611735 29279301 17069766 22946054 15474027 20840591 17442832 33550096 23413029 18264140 25361009 18063574 16511565 34007068 16155211 19604478 17353276
NFKB1 HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18498249 17898080
CBX4 BMI1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21282530 22078878 9199346 34316702 18453536 20601937 19636380 26496610 27705803 22325352 27647897 33961781 24981860 17332741 24457600 12829790
RING1 BMI1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 9858531 25416956 29402932 19451220 32296183 22493164 22897849 15386022 16751658 20601937 19636380 16359901 34316702 24457600 9199346 27705803 34133714 22325352 33961781 24981860
PHC1 BMI1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 9199346 20601937 19636380 27705803 22325352 27647897 15563468 33961781 24981860 23523425 9121482 9009205
BAP1 HCFC1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22683710 20805357 21642991 24703950 24211834 27705803 34591877 19188440 33961781 19815555 26416890 32509391 30463901 19615732
SUZ12 EED â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 24981860
AEBP2 EED â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15225548 29379173 21078963 29348366 27705803 26496610 33961781 24981860 26186194
AEBP2 SUZ12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15225548 29348366 27705803 33961781 35016035 26186194 24981860 27634302 24457600 31281901 20075857
EZH2 SUZ12 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 21135039 21884980 27338022 18931660 28068325 23079660 24469040 19026780 21190999 26496610 26748827 24320048 33849069 35016035 27634302 29669287 18285464 20543829 18453536 31130994 21123648 20123894 24183680 27728805 25470042 12435631 22939629 16224021 23624935 24457600 26344197 20075857 15882624 23684459 31786184 31281901 23238014 26130719 19026781 27705803 22439931 27303043 31631027 24981860 33961781 19734898 31948940 18483221 21378168
BCOR PCGF1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16943429 26687479 27505670 27107012 32628469 33468080 26496610 27705803 22325352 33961781 24981860 23523425
PCGF1 RING1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16943429 22493164 26687479 27505670 27705803 22325352 33961781 24981860
E2F6 RBBP4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12909625
BAP1 FOXK2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25451922 20805357 27773593 27705803 34591877 33961781 25609649 19815555 19615732 24748658
BAP1 ASXL2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 20805357 29284740 34591877 27705803 32669118 33961781 26186194 19815555 26416890 33731362 19615732
BAP1 ASXL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 26437366 22897849 20805357 21642991 34591877 27705803 32669118 33758188 32683582 20436459 19815555 26416890 34170818 33961781 23850490 19615732 26739236
PHC1 PHC2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 16713569 22325352 33961781 15563468 24981860 9121482
PHC1 CBX4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 21282530 22078878 9199346 26496610 27705803 22325352 33961781 24981860
CBX4 RING1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21282530 16189514 9858531 22078878 9199346 26496610 27705803 22325352 24981860 30317550
PCGF2 RING1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32296183 22493164 17936708 20601937 19636380 27705803 22325352 33961781 24981860 21516116
BCOR YAF2 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
RYBP E2F6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 16189514 12411495 11171983 27705803 22325352 33961781 24981860 26186194
E2F6 TFDP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32296183 16189514 25416956 9501179 20211142 9704927 27705803 33961781 24981860 26186194 26871637 15536069
EP300 HDAC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
NEDD4 UBE2D1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
PCGF2 PHC2 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
PCGF2 PHC1 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
CBX2 PCGF2 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
PHF19 RBBP4 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CDK6 RB1 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
HDAC2 SUZ12 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
PCGF2 PHC3 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
EED PHF1 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
EGLN2 HIF1A â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
AEBP2 EED â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
EGLN1 EPAS1 â—¼   PHYSICAL_INTERACTION 906.0 0.9 STRING 36370105
CBX8 PHC1 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
CREBBP HIST3H3 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
EZH2 EED â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 24981860
CBX6 RING1 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
CBX4 PHC1 â—¼   PHYSICAL_INTERACTION 909.0 0.91 STRING 36370105
RING1 PCGF2 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 24981860
ATM TP53BP1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
EED HDAC1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
EZH2 MTF2 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
PHC2 SCMH1 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
PHF1 SUZ12 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
PCGF5 RING1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
PCGF2 RING1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
PHC1 RING1 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
PCGF1 RING1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
PCGF6 RING1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
KDM2B RNF2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
KDM2B RYBP â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
RB1 RBBP4 â—¼   PHYSICAL_INTERACTION 915.0 0.91 STRING 36370105
EZH2 PHF1 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
CBX7 PHC2 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
PCGF3 RNF2 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
PCGF6 RNF2 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
PCGF5 RNF2 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
RNF2 YAF2 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
RING1 CBX8 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 24981860
RNF2 CBX8 â—¼   COLOCALIZATION ✅ 0.92 0.92 mint 5219708 17332741
BMI1 CBX4 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
RING1 YAF2 â—¼   PHYSICAL_INTERACTION 919.0 0.92 STRING 36370105
BMI1 PHC1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
NEDD4 UBE2D2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
PCGF1 RNF2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
EP300 RELA â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
EED RBBP7 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
DLAT PDHA1 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
HDAC1 RB1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
EGLN3 HIF1A â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
NEDD4 UBE2D3 â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
CREBBP RELA â—¼   PHYSICAL_INTERACTION 924.0 0.92 STRING 36370105
HCFC2 WDR5 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
PHC3 RNF2 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
CBX4 RING1 â—¼   PHYSICAL_INTERACTION 926.0 0.92 STRING 36370105
EED PHF19 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
CBX2 RNF2 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
EZH1 PHF19 â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
PCGF2 RNF2 â—¼   PHYSICAL_INTERACTION 929.0 0.93 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
ACO2 FH â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
H2AFX TP53BP1 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
CS PDHB â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
MTF2 SUZ12 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CBX7 HIST3H3 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
AEBP2 EZH2 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
E2F6 TFDP1 â—¼   PHYSICAL_INTERACTION 934.0 0.93 STRING 36370105
EGLN1 HIF1A â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
EZH2 PHF19 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
EZH2 RBBP7 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
RING1 RYBP â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
CBX7 BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 24981860
EZH2 HDAC1 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
HDAC2 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 26949739
CBX6 PHC2 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
EZH2 JARID2 â—¼   PHYSICAL_INTERACTION 939.0 0.94 STRING 36370105
RNF2 PCGF1 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 24981860
YAF2 KDM2B â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 27705803 22325352 33961781 24981860 27684187
RNF2 PCGF2 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 24981860
RING1 PHC2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 22325352 24981860 15386022 27705803
EZH1 SUZ12 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 19026780 19026781 27705803 33961781 24981860 27634302 24457600 31281901 20075857
CS IDH3A â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
PHC2 RING1 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CBX8 PHC2 â—¼   PHYSICAL_INTERACTION 942.0 0.94 STRING 36370105
DLAT DLST â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
EP300 SMAD3 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
CBX6 HIST3H3 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
EZH2 RBBP4 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
BMI1 CBX8 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
TFDP1 E2F1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
RBBP7 SUZ12 â—¼   PHYSICAL_INTERACTION 949.0 0.95 STRING 36370105
RB1 HDAC1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 6550000 10779361
CBX2 RYBP â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 10369680 24981860
SUZ12 EZH2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
EZH2 RBBP4 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 21123648 26496610 27705803 20123894 34518534 28068325 33961781 24981860 27634302 24457600
TFDP1 E2F6 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
CBX6 RNF2 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
DLAT DLD â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
PCGF1 SKP1 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
HIF1A EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17382325 5219810
CBX8 BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5219708 17332741
BMI1 CBX8 â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 5219708 17332741
EZH2 HDAC1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16189514 21685935 15520282 10581039 24771265 31130994 22439931 26344197
KDM2B SKP1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16943429 33692209 17704768 25533466 30596474 17463251 32628469 27705803 28614300 33961781 24981860 26725323 30033217
RING1 BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 24981860
RNF2 BMI1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 16710298 5218667
BMI1 RING1 â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 7998286 20601937
CBX2 RING1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 22325352 10369680 24981860 27705803
BCOR KDM2B â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16943429 26687479 25533466 27505670 26496610 24981860 33722704 29502955
RYBP RNF2 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 24981860
PCGF2 PHC2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 25416956 31093962 20601937 19636380 27705803 22325352 33961781 24981860
E2F6 RING1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 11171983 24981860 27705803
IDH3B IDH3G â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
CBX8 RNF2 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
CBX8 RING1 â—¼   PHYSICAL_INTERACTION 963.0 0.96 STRING 36370105
BMI1 PHC2 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
RB1 E2F1 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 5219804 17380128
E2F1 TFDP1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 31130363 25368385 20211142 28542143 35140242 9780002 8816798 8657117 9199321 19015639 8816502 16360038 15133492 8405995 30867845 8832394 7892279 7739537 9501179 9704927 27705803 22629304 24981860 9464260
HIF1A EP300 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15280364 19589782 16543236 11823643 22807441 19666581 16189267 18047470 15342390 12042299 19680224 22735262 23448368 26135796 23618863 14691445 19696166 11959990 27320910 16847340 24821806 22789427 17906695 8917528 20620956 20000859 15261140 16081065 12778114 22219185 15154850 25192544 22075993 19071119 22908229 19940151 21187066 24421387 23880760 11940656 23966271 26826385 26944191 12588875 23746844 11063749 27808477 19074848 20603618 15155277 18268343 20829524 21148070 12914934 17502379 22684029 17382325 26751287
HDAC2 RBBP7 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 22939629 20388487 27705803 21258344 33961781 24981860 26186194 15451426 12493763 9885572 26344197
RBBP7 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 19703393 10444591 21258344 11102443 9885572 17255935 10471499 26496610 25885317 22939629 9150135 23752268 9790534 27705803 33961781 26186194 19686092 15451426 12920132 26344197
CBX8 RING1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 21282530 25416956 32296183 10825164 20601937 26496610 27705803 24981860
HCFC1 WDR5 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
HDAC2 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25241761 9520398 11287668 19703393 30737378 17894944 10444591 11466315 11777905 21258344 15297431 17956988 11102443 9885572 12032298 19041848 26496610 22416134 12493763 11739383 10581039 11804585 11564889 21670149 22939629 9150135 11919195 23752268 18059533 16713569 9804427 20388487 9790534 26949739 24981860 33961781 15987735 19182791 15451426 12920132 26344197
EED HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 10581039 11124122 26496610 22439931
RBBP4 HDAC1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16189514 9520398 19703393 31435636 9150133 10444591 21258344 12943729 11102443 9885572 27068747 10471499 26496610 34518534 20127688 11171972 10734134 11470869 20585571 10220385 12091390 17643391 21670149 11602581 17827154 22939629 9150135 23752268 16713569 9790534 27705803 19686092 24981860 33961781 11302704 11118440 15451426 12920132 26344197
HDAC1 NFKB1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25241761 12972430 17962807 24448807 11931769 14678988 16319923 17827154
HDAC2 RBBP4 â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
EED HDAC2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 30737378 10581039 11124122 24981860 24457600
DLD PDHB â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
PHC2 BMI1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 25416956 16713569 27827373 34316702 16751658 20601937 19636380 25910212 27705803 22325352 33961781 24981860 9121482 24457600
EED RBBP4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 15225548 29379173 21078963 27705803 26496610 33961781 24981860 12435631 15385962
EED SUZ12 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 29379173 27338022 19026780 26496610 35016035 27634302 15385962 15225548 18285464 20543829 12435631 31786184 24457600 31281901 20075857 19026781 21078963 27705803 22439931 28320739 33961781 24981860 23280602 18483221
EED EZH2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 21135039 9584197 9742080 31948940 29379173 27338022 18931660 28068325 33754075 11158321 9584199 32296183 22897849 17937919 19026780 21190999 26496610 24320048 33849069 27634302 15385962 16314526 29669287 15225548 18285464 10581039 21123648 12435631 31786184 23624935 24457600 20075857 15882624 19026781 21078963 22094255 22439931 28320739 27705803 31527584 24981860 33961781 23280602 26344197
SUZ12 RBBP4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 15225548 27705803 33961781 35016035 24981860 27634302 22939629 24457600 31281901 20075857
RYBP RING1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16943429 28514442 10369680 16189514 25416956 32296183 34316702 27705803 34133714 22325352 30217970 33961781 26186194 24981860 17070805
DLST OGDH â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
EED RBBP4 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
EED EZH1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
EZH1 SUZ12 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
CBX3 HIST3H3 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
BMI1 RING1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
PHC2 RNF2 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
RB1 TFDP1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
HDAC2 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
HDAC1 RBBP7 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
BCORL1 PCGF1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
BCOR PCGF1 â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
HCFC1 OGT â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
HIST3H3 WDR5 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
AEBP2 RBBP4 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
CBX5 HIST3H3 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
PHF19 SUZ12 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
EED EZH1 â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 32296183 19026780 9584197 9566901 20211142 19026781 27705803 28320739 33961781 24981860
EED JARID2 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
KDM2B PCGF1 â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
KDM2A SKP1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
AEBP2 SUZ12 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
AEBP2 JARID2 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
KDM2B SKP1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CBX7 RNF2 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
E2F1 TFDP1 â—¼   PHYSICAL_INTERACTION 987.0 0.98 STRING 36370105
HDAC2 RBBP4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 31435636 21258344 12943729 9885572 34518534 12493763 12091390 21670149 17827154 22939629 16713569 9804427 20388487 27705803 33961781 24981860 11302704 15451426 26344197
DLAT PDHB â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
PHC1 RNF2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
ASXL2 BAP1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
HDAC1 RBBP4 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
CREBBP HIF1A â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
RBBP4 SUZ12 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
JARID2 SUZ12 â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
PDHA1 PDHB â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
IDH3A IDH3G â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EED SUZ12 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EP300 HIF1A â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EZH2 SUZ12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
H2AFX ATM â—¼   PHYSICAL_INTERACTION 105.0 1.0 ACSN 11283614 11331603 11571274 11850621 11877377 12086603 12202749 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001824 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20160076 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23030059 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
H2AFX ATM â—¼   SHARES_COMPLEX 105.0 1.0 ACSN 11283614 11331603 11571274 11850621 11877377 12086603 12202749 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001824 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20160076 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23030059 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
H2AFX ATM â—¼   ENZYMATIC_REACTION ✅ 105.0 1.0 ACSN 11283614 11331603 11571274 11850621 11877377 12086603 12202749 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001824 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20160076 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23030059 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
H2AFX ATM â—¼   REGULATES ✅ 105.0 1.0 ACSN 11283614 11331603 11571274 11850621 11877377 12086603 12202749 12234250 12556884 12607003 14614141 14988723 15136767 15140942 15175241 15211575 15242590 15279786 15375219 15377654 15385537 15459660 15485915 15496928 15498778 15549137 15655342 15798197 15964794 16163361 16332722 16449207 16531125 16713580 16805667 16818604 16858402 17055429 17102137 17116323 17116885 17296725 17303408 17384638 17582221 17660363 17965729 18001824 18001825 18006705 18087292 18171670 18171986 18212739 18398454 18469862 18524993 18543256 18558713 18583988 18584027 18590585 18678890 18809224 18995830 19151707 19202191 19217833 19270065 19282663 19342888 19362533 19490890 19622404 19654615 19686080 19772495 19793801 19892829 20021983 20027199 20051983 20064462 20160076 20691907 20713526 20723763 21376743 2191300 22657828 22743550 23030059 23082994 23161013 23253856 23847781 24036544 24050180 24089143 24095737 24709898 7575488 9407949 9488723 9721205
AURKB ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22099307 27493659
ATM HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 27245613 24681585 21095578 18971907 21095582 27027353 23573973 27068951 25956861 23707302 26942179
ATM E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 20972224 11459832 27679857 15494392 15140942 27028861 21543892 27025900 20860841 24741006 17570479 25101673 28812991 15838517 22174788
ATM EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20471956 15494392 15140942 29590107 26170237 21108945 15838517 27220480
ATM TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 11042216 17940005 26247731 18996087 19876065 16945145 12447390 22621922 18644834 19650866 24320053 18077418 17570479 17690115 17525332 12697768
E2F6 CBX5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 18319725 12909625
RB1 CDKN1B â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
E2F1 CDKN1B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15713665 21840777 22955272 23393547 19077036
CDK6 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 16160006 25241761 18615582 16782892 21439954 11360184
SKP1 CDKN1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15340381 15147722 12820959 16209941 11516665 15071497 15688063
E2F1 RB1 â—¼   PHYSICAL_INTERACTION 18.0 1.0 ACSN 11877377 15175241 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 19793801 20029420 21060331 21337561 24254977 7575488 7935440
E2F1 RB1 â—¼   PROTEIN_INTERACTION 18.0 1.0 ACSN 11877377 15175241 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 19793801 20029420 21060331 21337561 24254977 7575488 7935440
E2F1 RB1 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 11877377 15175241 15279786 15459660 16581787 17218262 17303408 17660363 17713585 18458534 18590585 19793801 20029420 21060331 21337561 24254977 7575488 7935440
ESR1 E2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22791811 20215421 12697671 10446910
E2F1 RB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 11533237 16081466 16738312 16188218 15618023 14681231 16230367 15985428 8264596 18583990 16601104 14627987 15016799 11268000 10490838 11818069
E2F6 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18562691 18319725 9689056 12004135 12909625
RB1 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 90.0 1.0 Omnipath 17145710 23472054 12502741 22078878 8896460 12397079 9315635 20839231 16249186 11839806 8255752 11713253 20871633 15837424 8346196 19249677 16360038 8626527 12096339 15485814 16374512 18391203 9125176 16766265 9468140 8816798 12598654 10393912 9400991 9632788 12947005 19477924 15485920 17380128 10523633 10869426 7828850 18216119 8657117 12963846 25257171 17488475 28074012 15670817 11583618 7739537 10499802 8413249 11090181 8230483 22768064 29521627 10207050 9553123 7958924 11420730 23001041 16496386 9501179 19058874 1388726 9422723
CDK6 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 9190208 10498883 18590585 7575488 9315635 17303408 10385618 10778858 9736735 16236519 20068082 7736585 9425340 11520855 19075565 18786381 17660363 15279786
CREBBP E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10753885 15126619 12748276 15123636 8932363
E2F1 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 20211142 15133492 22327218 7892279 16360038 9199321 8405995 9704927 8816798 9780002 8657117 9464260 22629304 7739537 27705803 25368385 9501179 8816502 8832394
E2F1 EED â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18319725 14532106
E2F1 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18319725 14532106
UBE2D2 EGLN3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
UBE2D1 EGLN3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
UBE2D3 EGLN3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
HIF1A EGLN3 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A EGLN3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19828020 15156561 20727020 15823097 22555025
EPAS1 EGLN3 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 5.0 1.0 Reactome 12615973 12788921 19208626 18337469 18184961
HIF1A EGLN3 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 16.0 1.0 Reactome 11292861 15652751 17182618 12615973 12788921 11598268 11292862 21335549 17434750 15474027 15247232 12351678 12912907 15987702 22286099 18337469
EGLN3 EPAS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 12788921 23275444 17684156 17353276 15474027
EGLN3 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 17145710 15652751 26972000 15721254 16391536 16511565 24990963 12351678 31515488 24145445 17353276 15474027
EP300 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19608861 25400040 11567019 12419806 17617622 11533489 20333651 12456660 15152190 16846590 9096323 20064247 16382138 16713569 15171256 16135789
EP300 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 75.0 1.0 Omnipath 24821806 12573436 17145710 16847340 12588875 19589782 11940656 25192544 11959990 18519678 23448368 22219185 11823643 12042299 15342390 23746844 19071119 19680224 27808477 15154850 19696166 8917528 17906695 18268343 22735262 21148070 15261140 19940151 23880760 22807441 35430356 14691445 12914934 20000859 12778114 26751287 16081065 22789427 16543236 24421387 17382325 17502379 22684029 21187066 19074848 23618863 23966271 20603618
EP300 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9843571 11134049 12743039 15133024 15824515 15623506 16876108 21567395 16109717 17074756 20564330 10497242 15588252 17469184 15345715 11058129 10575014 16862174
EP300 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23331499 12408818 10887155 15831498 21269274
EP300 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11486036 7758944 18542060 9199306 17510411
AURKB TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 28415769
UBE2D3 HIF1A â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
UBE2D3 EPAS1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
UBE2D3 EGLN1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
UBE2D3 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10835356
NFKB1 YY1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 17438126 21725609 23178297 23572150
YY1 IDH3A â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12150925 12408816 12533512 12906785 15755954 16469695 17680028 18046414 18048642 18492954 19022819 19568798 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
AURKB YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23226345
HDAC2 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9016636 19139378 11486036 8917507
RB1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12588874 11118439
UBE2D1 EPAS1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
UBE2D1 HIF1A â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
UBE2D1 EGLN1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
RB1 CDK6 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 10207050 9447971 24876129 31543423 11416152 11032757 9190208 30711375 10499802
CDKN2B CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 26186194 26578655 23602568 25416956 32296183
CDK6 RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 43.0 1.0 Omnipath 10498883 9315635 17303408 11416152 15081408 16236519 19690332 16936279 11520855 16107892 19413330 15279786 16360038 9190208 14627988 7575488 24417566 8822197 10385618 9736735 9139732 7736585 19075565 29372101 18590585 27507850 22682621 20068082 9425340 25549286 18786381 17660363 15809340 27811360 10778858 9380698
CDK6 TFDP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 9190208 10498883 9315635 10385618 10778858 9736735 7736585 9425340 11520855
SMAD3 SMAD7 â—¼   PHYSICAL_INTERACTION 13.0 1.0 ACSN 11279127 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21614932 22331441 23784029 8515656
SMAD3 SMAD7 â—¼   PROTEIN_INTERACTION 13.0 1.0 ACSN 11279127 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21614932 22331441 23784029 8515656
SMAD3 SMAD7 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11279127 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21614932 22331441 23784029 8515656
SMAD3 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10823886 15183844 12761881 10887185 10973944 10839991 10753944 10843994 15579469 10559222
SMAD7 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 21071413 9892009 26555259 9892110
SMAD3 CDKN2B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14647420 15326485 23032366 16819512
CREBBP SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 15849193 10497242 15467747 18003620 9679056 15990875 15750622 19589780 17074756 17283070 9679060
SMAD3 MAX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 25241761 16189514 12551947
SMAD3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11555647 23331499
SMAD3 CDKN2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9389648 11013220 10454538 9670020 11283613 11074002 11283614
IDH3B IDH3A â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 28514442 16713569 31515270 14681455 33961781 26186194 10601238 14555658
IDH3A IDH3G â—¼   PROTEIN_INTERACTION 1.0 1.0 HIPPIE 28514442 10677231 14681455 28098230 33961781 26186194 14555658 26344197
HDAC1 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 HDAC2 â—¼   PHYSICAL_INTERACTION 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   SHARES_COMPLEX 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC1 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 11283614 12545156 12668723 15151915 15155580 15465827 16232121 17055429 17508028 17550342 20027199 20713526 20818389 21234400 21733352 2191300 21919891 22370643 22796940 23140366 23869868 9618481
HDAC1 HDAC2 â—¼   UP_REGULATES ✅ + 28.0 1.0 ACSN 11283614 12545156 12668723 14673164 15151915 15155580 15465827 16232121 17018611 17055429 17508028 17550342 17563753 20027199 20713526 20818389 21234400 21577210 21685935 21733352 2191300 21919891 22370643 22514743 22796940 23140366 23869868 9618481
HDAC1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 21655924 23242655 18316616 20101232
HDAC1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11564889 11931769 16483679 30670829 16325585 16713569 17183360 21983014
HDAC2 EZH2 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
HDAC2 EZH2 â—¼   SHARES_COMPLEX 8.0 1.0 ACSN 15465827 17018611 17563753 21234400 21577210 21685935 22514743 22796940
MAX MGA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 21988832 20936779 25609649 27705803 7954804
AURKB RB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 27496133 27933271 19225156
NFKB1 SKP1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
SKP1 RELA â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
PDHA1 DLD â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
NFKB1 RELA â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
RELA NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 16778171 20427719 23362108 16513645 1740105 20596645 16513841 19469019 8454856 21420936 16135789 9417120
RELA HIF1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18498249 17898080 23185316
NFKB1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 17145710 16209943 25609649 8428580 12947093 16970925 17072323 2050119 15657065 21270162 11976329 16793322 21544861 22261743 8657102 9824778 11880271 9450761 17962807 21988832 25355951 9722548 18215660 14743216 15799966 10799898 16105840 15218526 8798655 14690596 22139845 22808155 11571291 17072327 16740634 10498867 8255759 8246997 15214841 16846590 15371334 16285893 17072322 17855547 18321863 16493424 7479976 15145317 17561400 20110362 9426183 23687337 12414801 11970949 20154269 20237821 24175631 24634218 34100597 14645533 17982102 21763497 16204234 9437432 20547752 15818410 7628694
CREBBP RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 10542243 14597638 18241676 17138826 15140884 9096323 16713569 12456660 10454579 16382138 19608861 9806899 25314079 11931769 12163591 12881425 9659924 15171256 9548485 16291753 17362989 25733689 17434128 15334063 15806143 10235267 17296604
HIF1A CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12542982 20547241 17452336 15907483 19489936 15342390 15184875
CREBBP ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 9192902 18765668 16417649 11113179 8616895 11782371 14766010 17400812
UBE2D2 HIF1A â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
NFKB1 HIF1A â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 17272744 18393939 21725609 23178297 23572150
HIF1A EGLN2 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A EGLN1 â—¼   ENZYMATIC_REACTION ✅ 66.0 1.0 ACSN 10102273 10428030 10428780 10435632 10804084 10823814 11557773 11559532 11744734 11756417 11884613 12402042 12676992 12743597 14672622 14684737 14699081 14762718 15024076 15059920 15199147 15240700 15312748 15369676 15379897 15545625 16110315 16126909 16127144 16517405 16517406 16585195 16782875 16888645 17143338 17418790 17533374 17785433 18054315 18056423 18158893 18718909 19211554 20028863 20427344 20535745 20855962 21051947 21765015 22006996 22841746 22850421 22988108 24006507 25043024 25103413 25732824 7493931 7500013 7508926 8089148 8702901 8955077 9486205 9525945 9707622
HIF1A ENO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19828020 8955077 15459207
HIF1A EGLN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 23487784 12839937 22075993 20574527 15563275 19628018 18072750 24558194 22451659 16157596
HIF1A EPAS1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20513003 18174278 16924414 19030186
HIF1A EGLN1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 16.0 1.0 Reactome 11292861 15652751 17182618 12615973 12788921 11598268 11292862 21335549 17434750 15474027 15247232 12351678 12912907 15987702 22286099 18337469
HIF1A EGLN2 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 11.0 1.0 Reactome 11292861 12615973 12788921 11598268 11292862 21335549 17434750 15474027 15247232 12351678 12912907
EGLN1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 19604478 20840591 16511565 23413029 12351678 15474027 22946054 15652751 16407130 25361009 31763849 32755251 16391536 15721254 20724477 24145445 17353276 18264140 26611735
EGLN2 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 15652751 16391536 15721254 16511565 24990963 11292862 12351678 24145445 17353276 11292861 15474027
RB1 HIF1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15674338
EZH2 FGFR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 22179855 22312437 21512140 23933322 24737471 23932971 23918806 19053175 19502792 24928441 23424038 24032713 24474760 20634887 18704159 24652950 22072987
ESR1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8114761 9528985 18414489 10037443 21813366 11726205
BMI1 RNF2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
BMI1 RNF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 16710298 22493164 22902369 20068231 22325352 25355358 17157253 16751658 26496610 16714294 26468281 26151332 12183370 12589020 21772249 25843776 20601937 32296183 21676867 27647897 15563468 27705803 16359901 24457600 19636380
EED EZH2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
EZH2 ASXL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19934320 18687996 24771265 24132643
RNF2 RYBP â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
UBE2D2 EGLN1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
EPAS1 EGLN1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 5.0 1.0 Reactome 12615973 12788921 19208626 18337469 18184961
EGLN1 EPAS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12788921 30487161 16407130 23275444 19147576 17353276 19208626 15474027
UBE2D2 EPAS1 â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10878807 9891082 12101228 10535940 12538644 11454738 22286099 10973499
PDHA1 DLAT â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 11752427 2188967 11935326 9242632
EGLN2 EPAS1 â—¼   OXIDOREDUCTASE_ACTIVITY_ELECTRON_TRANSFER ✅ 4.0 1.0 Reactome 12615973 18184961 12788921 19208626