Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CHEK2 NSD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 19001859 12364621
NSD2 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
CHEK2 NSD2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16651405 10724175
NSD2 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19340300
NSD2 NSD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23011637 20599755
H3-5 NSD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
NSD3 SEPTIN6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
HOXC4 NSD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
NSD3 UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
RPL30 NSD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
GLYR1 NSD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
NSD3 DOCK7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
NSD3 CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8153045 21516116
DAXX NSD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
NSD3 MNDA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
NSD3 SLU7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
EPB41 NSD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
NSD3 SPAG8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
NSD3 STAC3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
ZNF57 NSD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
NSD3 ETV3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
MYC H2BC8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12747840
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
MYC CBX5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ESR1 CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24559156 10851069
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
NSD2 H31 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 34271259 19481544 25494638 34079125 25281560 26912663
NSD3 H31 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 34271259 33361816 25494638 26912663 34079125
CBX3 NSD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20936779 34079125
KDM1B NSD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 20670891
ESR1 H31 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
DAXX CBX3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 34079125
MYC CBX3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
DAXX CBX5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 24981860
MYC SLU7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
NSD2 ESR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24101509 31527615
BRD2 NSD3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30554943 26496610 31753913
BRD2 CBX3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30554943 31753913 34079125
GLYR1 KDM1B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NSD3 MYC â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31638140 28205554 28628118
DAXX H31 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 28514442 25275136 23142979 33961781
H31 GLYR1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 29568061 34079125 26527279 26912663
NSD3 ESR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31527615 25640309
H31 KDM1B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23266887 25281560
CBX3 CBX5 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
DAXX UBE2I â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CDKN2A MYC â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
MYC IRF3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
CBX5 CBX3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 15306854 17314413 34079125 20562864 11336697 16713569 19498464 27705803 21888893 20231385 20850016
MYC CBX3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC CBX5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC FGFR4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
RAD51 UBE2I â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
CBX5 H31 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 19783980 16687578 24981860 25281560 20011120 16415788 34079125 19498464 28514442 26157143 26527279 16622419
H31 CBX3 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 24981860 20011120 33097091 16415788 34133717 24576085 15136563 26527279
ESR1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11029009 15569929 18450422 20664923 15496458
AKT1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 18521086 26944939 11108261 17627277 20101208 17570479 15604293 23169992 26554417 16452229 15193262 7838153 12374744 11139588 26272591 11432835 20179234 11507039 9528769
MYC CASP8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15367674 12695333
MYC CDKN2A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199070 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364 9694806
MYC CDKN2A â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11274345 11283613 11283614 11704864 15199070 17055429 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21406394 2191300 22067385 25002027 28536364 9694806
MYC CDKN2A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 15361884 11593429 11507042 20023701 23342141 16537449 23277542 10914736 9212167 12835716 24177224 11062467 15199070 18762810 19786833 20551174 11360201 23722468
MYC CDKN2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 15361884 9308237 10373560 17936558 12209154 12738781 17873522 11283613 21406394 9312026 15095404 17558397 20551172 19901969 19815509 10504341
PPM1D CHEK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 12855706 16311512 10973490 23666059 20599567 16936775
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
MYC TGFB1 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
MYC RAD51 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 20940401