Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NSD3 DOCK7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
AKT3 TSC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12150915 12172553
AKT3 BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22505453
SNCA AP3B1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
YWHAG ARHGEF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
BCL2L1 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BCL2L1 BCL2L14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16189514 11054413
CAPZB CAPZA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
DOCK7 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12432077 29187380
SOX2 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath
YWHAZ CLTC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
COPS5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18926707
CRLF3 SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DCAF7 YWHAG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
YWHAG DOCK7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
DOCK7 TRIM63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
DOCK7 TRIM55 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
NBEAL2 DOCK7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29187380
NRG1 ERBB3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10768865 23365119
EZR YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
MYC TRIM63 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
MYC TRIM55 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
YWHAH SNCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TK1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
VAC14 TRIM55 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 31391242 233395
YWHAG TSC1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
DOCK7 CDC42 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 12432077 31871319 18426980
CFTR YWHAG â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
CFTR YWHAZ â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
1433F CBY1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
1433F LRCH2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CDN1A DOCK7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21900206 23443559
ANXA7 MOB1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRRK2 AP3B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24725412 27424887
AVIL DOCK7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BMI1 CAPZB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34316702 24457600
CDC42 MYO6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20936779 31871319
MYC CTBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 34147029
CTBP1 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15834423 21102443 16122695 35016035
DCAF7 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31753913 35016035
DOCK6 LRCH1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 32203420
TMOD3 DOCK7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DOCK7 LRCH2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24255178 32203420
HDAC6 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15102857 19344692 12718889 22778253 23133622
LRCH3 LRCH4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LRCH3 TMOD3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MARK4 1433F â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16959763 14676191
1433F DOCK7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 14676191
PIHD1 DOCK7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PE2R3 ERBB2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PE2R3 DOCK7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ARPC3 DOCK8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ARPC3 LRCH2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ARPC3 DOCK7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DOCK8 CDC42 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31871319 15304341 16189514
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
CLTC MYO6 â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
LRCH3 DOCK6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24255178 32203420
DOCK8 DOCK6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24255178
MOB1B DOCK7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24255178
DOCK8 LRCH2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24255178 32203420
LRCH3 LRCH1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24255178
LRCH3 LRCH2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24255178
MOB1B MOB1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24366813
SNCA YWHAH â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
LRRK2 YWHAG â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
NSD3 MYC â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31638140 28205554 28628118
CDC42 CAPZB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31478661 31980649
DAPK1 CAPZB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25852190 32707033
CDC42 TMOD3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31478661 31980649
DAPK1 TMOD3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25852190 32707033
DOCK8 LRCH4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 28514442 32203420
MYC TSC1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28205554 29467282 28628118
CDKN1A EP300 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
CBY1 RASSF10 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HuRI 32296183
1433F LRRK2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 23075850 31046837 20642453 29541021
LRRK2 CDC42 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21048939 21454543
CFTR TMOD3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 17110338
DOCK7 LRCH3 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
1433F DCAF7 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17979178 14676191
DOCK7 DOCK6 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 29467281 24255178
MYO6 DOCK7 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 27018747 29467281 26950368
HDAC6 ERBB2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31980649 20029029
ERBB3 HDAC6 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31980649 20029029
RAC1 LRRK2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21454543 31046837
NRG1 ERBB3 â—¼   PHYSICAL_INTERACTION ✅ + 0.86 0.86 Signor 7514177
PIHD1 LRCH3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26186194 32296183
DOCK8 DOCK7 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24255178 32203420 29467281 28514442
LRCH4 DOCK7 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 29467281 24255178 32203420
DOCK7 LRCH1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 29467281 24255178 32203420
MYC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12776737 16287840 32140074 15616592 16126174 17157259
MOB1B LRCH2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 24255178
PARK2 SNCA â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
ERBB2 GRB7 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
TSC1 1433F â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 12176984 17979178
CDC42 RAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
LRRK2 YWHAH â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAG YWHAZ â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
YWHAG YWHAH â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
DOCK8 LRCH1 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
YWHAH YWHAZ â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
MAP1LC3B NEDD4 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
MYC MLH1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29467282 12584560
GRB7 DOCK7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GRB7 ERBB3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22973453 24189400 9516479 16273093 16189514
GRB7 ERBB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9079677 12061724 7907978 22973453 12975581 16273093 17875712
ANXA7 DOCK7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DOCK7 BCL2L1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CAPZB RPP14 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DOCK7 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
RPP14 DOCK7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PPP2CB DOCK7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SMN1 DOCK7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SNCA DOCK7 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
DOCK7 TK1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
TMOD3 MAP1LC3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TK1 MKI67 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MKI67 SMN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MYC SMN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
PPP2CB SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21562258
LRRK2 YWHAZ â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
ERBB2 ERBB3 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
CBY1 YWHAZ â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
ERBB3 NRG1 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
ERBB3 ERBB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22806884 25898135 30523157 9130710 21278786 15812817 20227043 16843263 10572067 19411071 19060928 8665853 10799311 8816440 17426253 17148612 21075308 12896906 15504738 23680147 23688700 23866081 22733765 7592681 21203579 25326665 24557338 23436906 30898150 7538656 25241761 25315821 11173924
CAPZA1 CAPZB â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
ERBB3 GRB7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 24189400 16273093 9516479 16189514
PPP2CB AKT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 18039929 19216069 10026142 10995457 18042541 20452955 18559511 18588945 16680151 16406523 18160256
AKT3 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 12851486 15023346 19216069 17680028 11756412 16680151 20214616 11463845 23109003 20452955 9829964 20398329 17646672 10217147
ARHGEF2 RAC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11595749 16189514 9857026
MYC BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 14517295 18802399 16316993 17331788
MYC BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
CDC42 DOCK6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15710388 15247287 12134158 17196961 17027967
DOCK8 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15304341 16189514 28028151
DOCK6 CDC42 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9490022 9113980 10816584 17045588 8836113
MYC CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 15190211 14519204 15616584 12408868 19174556 21949397 10319992 12553001 16204065 12545156 20878079 21042278 21400515 20190815 16706751 23804320 15757889 10920185 19270520 16452181 12408820 15528212 22371483 12565816 17885207 12384701 11274368 19150257 20551174 15899785 21120446 15071503 15474507 22814619 12835716 12748190 16738884 15711923 18636159
EP300 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10362258 15509808 21858218 22000024 21245169
MYC CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15528212 9618481 12545156 17550342 10454538 15155580 11283613 10920185 11283614
DNM2 CLTC â—¼   PHYSICAL_INTERACTION 8.0 1.0 Reactome 10480952 7650016 7592972 10593899 14731593 2121367 9497313 8939989
DNM2 CLTC â—¼   GTPASE_REACTION ✅ 7.0 1.0 Reactome 10480952 7650016 7592972 10593899 2121367 9497313 8939989
DAPK1 PPP2CB â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 12598906 17703233 18582460 19543238 20495383 21172648 21172653
DAPK1 PPP2CB â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 12598906 17703233 18582460 19543238 20495383 21172648 21172653
DAPK1 TSC1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11323415 17703233 18974095 19180116
RAC1 DOCK6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 15710388 15247287 12134158 17196961 17027967
ERBB2 DOCK7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18426980 27018747
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
NRG1 ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12082616 8651595 10768865 12471041 12374700
MYC ERBB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20920219 21627565 7906953 23421821 20716114
NRG1 ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 9275162 1350381 19293191 14737100 7514177
ERBB2 ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 17145710 23680147 17148612 24557338 19411071 21203579 7592681 23688700 23331499 21278786 12648465 22806884 27531070 17570479 30898150 29066975 17426253 16843263 9130710 20227043 25241761 10799311 8816440 22733765 10572067 19060928 11173924 21075308 23436906 7538656 15504738
NRG1 ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 10970856 16843264 7514177 7592681 23331499 8702572 7477375 11555649 9565587 16189514 26148232 9168115 9275162 10214951 17697999
LRRK2 SNCA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20127702 22924508 22658533 24907399 19576176
PPP2CB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16987807 16680151 15048125
TSC1 RAC1 â—¼   DOWN_REGULATES ✅ - 11.0 1.0 ACSN 11955434 12829230 12906785 15611338 15851026 15967165 16636147 17680028 18974095 19022819 20146692