HDAC1
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18691180
9650586
|
PCNA
|
CDK6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16713569
9667749
|
PCNA
|
CCND3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16189514
7908906
|
CDK6
|
CCND3
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
CCND3
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16609025
|
PARP1
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
23045548
23319653
|
CCNB2
|
CCNE2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1001737
24358021
|
HDAC1
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20049841
20821348
|
STAT3
|
CCND1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
11279133
|
CCND1
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11279133
|
CDK4
|
CCND2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
20156660
27107012
|
SKP1
|
CDC20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
12791267
10023660
|
STAT3
|
CDK4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22218594
|
PARP1
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
23045548
23319653
|
MDM2
|
MDM4
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
17159902
5219425
|
SKP2
|
SKP1
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
CCNA2
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
CCND1
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
805.0
|
0.8
|
STRING
|
36370105
|
CDK1
|
CCNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
14681455
8565853
16009130
1628647
7799941
|
CDK2
|
P53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
10884347
10747897
12064478
10348343
25241761
19556892
|
CDC6
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
25241761
15232106
|
CDN1A
|
UBP11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
29666278
23443559
|
CDN1A
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
25241761
20154723
16082198
|
SKP1
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
16376880
25241761
27215384
|
DDB1
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.81
|
0.81
|
HIPPIE
|
24249678
26679995
25189618
34026424
|
CCNE1
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
814.0
|
0.81
|
STRING
|
36370105
|
CUL4A
|
SKP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22474075
21145461
|
GA45A
|
GA45G
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
11498536
16189514
|
P53
|
PSMD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32807901
22653443
|
P53
|
SKP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23443559
22653443
|
CDN1A
|
TBA1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21900206
23443559
|
CDN1A
|
DOCK7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
21900206
23443559
|
PSMD2
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
18086887
29777785
|
CKS1
|
CCNE2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
CKS1
|
CCNE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
28514442
|
CDK2
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
21319273
|
PSMD2
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
20479273
18086887
|
CDC20
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
826.0
|
0.82
|
STRING
|
36370105
|
PCNA
|
CCNE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
PCNA
|
CCNE2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
CDN1A
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
26613412
30945288
18794347
|
CCNA2
|
CCNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
GA45G
|
CCNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12124778
|
KITH
|
P53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
21900206
16169070
16713569
32807901
|
TS101
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
11172000
17060450
|
CDN1A
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
18703516
18794347
23443559
|
PSME3
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
27215384
21445096
17588519
|
CDC20
|
CKS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
15014502
28514442
33961781
|
CDK5
|
CCND1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
23455922
33961781
21654808
|
CDK5
|
CCNE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
23455922
23602568
33961781
|
SKP2
|
CDC20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
20663873
26811472
15014502
28514442
25306918
|
CDK1
|
CDK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
CDK5
|
CDK14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
28514442
26186194
|
CCND3
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
PCNA
|
CCNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
8101826
33961781
7903056
|
TS101
|
P53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
11172000
16713569
16189514
|
CDK4
|
P53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28218424
28205554
28628118
|
MDM4
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
18086887
21148311
|
CCNE1
|
CDK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
9716181
28205554
28628118
|
CCNE1
|
CDK6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
9716181
28205554
28628118
|
CDK1
|
CDC20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
28514442
26912231
10799291
|
CCNA1
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
HDAC1
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
845.0
|
0.84
|
STRING
|
36370105
|
P53
|
CCNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
10884347
16713569
|
CDN1A
|
CSK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
10679299
16713569
|
CCNB2
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
33961781
15232106
|
CDN1A
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
25241761
10764767
16189514
|
CDC20
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
33961781
30833792
17679094
33751805
23443559
|
CDN1A
|
CKS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
33961781
28514442
30833792
23443559
|
CDK6
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
856.0
|
0.85
|
STRING
|
36370105
|
CDN1A
|
MKRN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
34504644
19536131
|
SKP1
|
CCNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
33961781
9858587
33422522
26496610
16209941
|
CDK2
|
CDC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10339564
9566895
9889196
|
CDK1
|
CDC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
10339564
21041660
|
PARP1
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
19470756
34079125
16204234
20596014
|
CCNA1
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
CDK1
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
868.0
|
0.86
|
STRING
|
36370105
|
P53
|
MKRN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
19536131
31367258
|
SET
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
12407107
16474839
16189514
27626385
|
CDN1A
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
20086099
17373842
14761977
25241761
20308078
14633995
|
CDK5
|
CCNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
23455922
33961781
|
CDC20
|
CCNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
23239745
20383333
25161877
31230944
20080579
25306923
10799291
20733055
25482201
23091007
32152539
19820702
25825779
22014574
12956947
24151075
23007861
17360335
22193957
19826003
26912231
14701726
23791783
27522463
25246557
31455778
18471975
23288039
23979597
11562349
26387737
33082289
11804586
25505175
|
CCNE2
|
CDK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
28514442
26186194
9840943
|
CDK2
|
CDC20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
23455922
26811472
25852190
28514442
|
CDK5
|
CDK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
25852190
23455922
33961781
28514442
|
CDK3
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
28514442
23602568
26186194
|
CCND2
|
CDK5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
CDC20
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
872.0
|
0.87
|
STRING
|
36370105
|
CDK2
|
SKP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
CCNE2
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
PCNA
|
CCND3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
16189514
7908906
|
DTL
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
30649446
17041588
21145461
16861906
21628527
31155351
16949367
30623174
29424068
23478441
31973889
23555860
|
UBP11
|
P53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
19615732
33567341
25471832
34141823
|
CDK1
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
24218572
30833792
17679094
26496610
26186194
32707033
21308745
28514442
23602568
11559705
23543736
|
KITH
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
11389691
16189514
|
CKS1
|
CCNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
33422522
18471975
26496610
11907280
16209941
19483727
26186194
28514442
|
CDK5
|
CCNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
23455922
25852190
26186194
28514442
23602568
32707033
|
CCNB1
|
CDK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
27030811
28514442
|
CDK4
|
CDK6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
23455922
28205554
28628118
|
CDK5
|
CCND3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
23455922
32296183
26186194
28514442
23602568
|
PSME3
|
P53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21084564
18309296
|
P53
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12897156
17371838
33149608
11896572
16616141
25241761
27626385
21900206
9121469
33503543
|
P53
|
HDAC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
14976551
20075864
17827154
19011633
10521394
16697957
10777477
16107876
11099047
32494626
16959611
11313951
12426395
18765668
22266186
19303885
25241761
26539911
20633551
|
CDK5
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
15890360
23455922
30833792
23602568
23443559
|
CDK3
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
24218572
32296183
9811456
26186194
28514442
23602568
23443559
|
CDN1A
|
DTL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
18703516
21628527
20606006
18794347
23213251
|
SKP2
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
17477906
15980415
30833792
17679094
16376880
13678583
25241761
19686743
32035614
23261596
18794347
|
PARP1
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
23169665
20303835
20302655
12930846
|
CDK6
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
20102411
15232106
16713569
28514442
16189514
10022865
|
CCNB1
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
30833792
17679094
25241761
15251430
23443559
11559705
16082198
8662825
|
PSA3
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
20086099
20308078
16713569
11350925
16189514
|
CKS1
|
CCNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
30674583
18471975
26496610
28514442
19786724
|
CDC20
|
CCNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
33961781
26496610
23007648
26960431
19098431
25669885
20733051
25750436
32152539
25306918
19483727
28514442
19826003
10679238
27522463
26811472
31455778
32307883
18471975
26186194
|
CDK1
|
CCNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
14681455
33961781
33422522
17679094
25852190
26496610
24302728
19483727
12853968
26186194
21308745
8463339
28514442
9053846
23602568
32707033
|
CDC6
|
CCNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9566895
10339564
9889196
|
SKP2
|
CCNE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11237742
22959436
10790373
|
CCND1
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.89
|
STRING
|
36370105
|
HDAC1
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
14988403
11929879
16189514
16713569
|
PCNA
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20605778
11463845
25502805
33961781
26496610
9545252
11254741
30301766
11559705
23443559
29510343
9465025
26272819
16616141
16474839
9546435
7911228
22383522
17588519
16510448
8861913
11350925
16082198
11302688
8662825
7780738
19895794
8861969
10022118
27107012
32296183
25411249
15576034
30217970
7915843
19704162
18086887
21988832
11313979
10873631
25416956
28514442
16189514
23223023
21415862
30833792
20606006
31112565
12964161
26186194
30623174
17115032
12930846
|
PCNA
|
CCND1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21654808
8101826
33961781
7903056
7908906
15681588
|
PCNA
|
DTL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16861906
25154416
21725088
30301766
30623174
29424068
20129063
|
PCNA
|
CDK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
10930425
|
CCND3
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
27107012
33961781
32296183
30833792
25416956
9716181
23880157
25241761
26496610
15232106
30217970
26186194
21988832
8756624
16189514
23443559
|
CCNA1
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
32814053
10022926
12383116
16009130
15232106
16982699
25241761
26264872
8756624
16189514
7478582
29997244
|
CDK5
|
P53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12064478
10884347
17591690
11483158
|
MDM4
|
P53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
31462704
10827196
19255450
22745160
23671280
31066983
10075736
10629057
11528400
15604276
24445145
19521340
19075013
12370303
30598450
21965653
19432880
16024788
31152661
21088494
22807444
17301054
30832340
17875722
16713569
20724842
28628118
16227609
30672125
25464845
25825738
22266850
24659749
20515689
21075307
20174603
18316739
17110929
20705607
10608892
24127580
29023092
26876197
24667498
9226370
18677113
27114532
28514442
22374672
17080083
8895579
12393902
29523541
32511789
30045945
19305137
23028042
18485870
11223036
26148237
25609649
19153082
26186194
21925390
28205554
23946421
28487147
15916963
12874296
25961923
27249653
|
P53
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12898523
14627987
9565608
32807901
16713569
9312059
23169665
15044383
|
CDN1A
|
CCND2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
27107012
33961781
32296183
15169570
9823309
25416956
25241761
11971966
30217970
26186194
8756624
16765349
16189514
23443559
10022865
|
GA45A
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10912791
7478594
10973963
16189514
16772293
|
CDN1A
|
CDK14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
17517622
26186194
28514442
23602568
|
CCNE1
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
11477082
24771265
9218599
16765349
23443559
8242751
9716181
13678583
8662825
9472014
9380407
9632134
12839982
21988832
8756624
9660939
30833792
17293600
8891332
25241761
|
BCCIP
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
14726710
10878006
19713748
|
CCNE2
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
9840927
30833792
9840943
26496610
15232106
26186194
24358021
28514442
23443559
|
CCNA2
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
15890360
9380407
8242751
33961781
30833792
17679094
9632134
26496610
26186194
21308745
8756624
12947099
9660939
23443559
8662825
|
SKP2
|
CKS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
12140288
15980415
11463388
19786724
11231585
23589337
12529174
16979657
16209941
12813041
28514442
18239684
16189514
33422522
15772084
16338391
17409098
18519678
|
CKS1
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
33961781
26344197
25852190
18471975
22939629
9774639
26496610
26186194
32707033
25416956
23602568
19786724
|
SKP2
|
CCNA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
20160477
33989513
9858587
33422522
24632684
15355997
7553852
26496610
16209941
27720894
31181401
26186194
10559858
28514442
18604603
|
SKP2
|
CCNA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
9858587
15355997
33989513
|
CCNA2
|
SKP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9858587
15355997
33989513
|
CDK6
|
CCND2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
16189514
9178893
30217970
11360184
28205554
16713569
28628118
23602568
11358847
10022865
|
STAT3
|
CCND2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24287565
12147685
|
STAT3
|
CCNE1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
22583478
19049964
19010822
|
SKP2
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
33961781
20160477
23455922
26496610
22770219
23602568
7553852
9636170
9858587
15355997
25852190
10386600
16979657
28514442
16189514
18604603
33422522
19686743
19270695
26186194
10559858
|
MDM4
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
26720344
33961781
27621617
26359458
10827196
10629057
24755078
23671280
22902369
22745160
22333590
15604276
20484049
18566590
12370303
30598450
31796886
10218570
19432880
34551723
12483531
29524278
17159902
27777309
12860999
27215386
11606419
18219319
17301054
19683495
25512388
20724842
28628118
16227609
22493164
20473904
25384516
26001071
25825738
22266850
29057323
25809483
25703327
32427989
20705607
10608892
31024344
19619542
21988832
29262653
25659040
29523541
28514442
27617579
29295817
33985974
12393902
16055726
23028042
24813712
22120712
32300648
32075226
21925390
17616658
28205554
23946421
19838211
25105592
12874296
25961923
|
PSME3
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21084564
18309296
24583282
|
CCNA2
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
901.0
|
0.9
|
STRING
|
36370105
|
CCND2
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
903.0
|
0.9
|
STRING
|
36370105
|
CCND3
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
904.0
|
0.9
|
STRING
|
36370105
|
GA45A
|
CCNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.91
|
0.91
|
HIPPIE
|
12124778
10362260
|
CDK2
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
911.0
|
0.91
|
STRING
|
36370105
|
CCNB2
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
CDC20
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
CCND1
|
CDK6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
919.0
|
0.91
|
STRING
|
36370105
|
CKS1
|
CCNB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
33961781
28514442
19786724
|
CCNE1
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
920.0
|
0.92
|
STRING
|
36370105
|
CCNA2
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
929.0
|
0.92
|
STRING
|
36370105
|
CUL4A
|
DTL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
930.0
|
0.93
|
STRING
|
36370105
|
CDC20
|
CCNA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.93
|
0.93
|
HIPPIE
|
19477924
10679238
|
MDM4
|
MDM2
|
â—¼ COLOCALIZATION
|
✅
|
|
0.93
|
0.93
|
mint
|
17159902
5219425
|
CCNA1
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
933.0
|
0.93
|
STRING
|
36370105
|
CCND2
|
CDK6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
939.0
|
0.93
|
STRING
|
36370105
|
CDK2
|
CDK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.94
|
0.94
|
HIPPIE
|
28514442
23455922
26186194
33961781
|
CDK2
|
CDC6
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.94
|
0.94
|
Signor
|
10339564
|
CCNA2
|
CDC6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
946.0
|
0.94
|
STRING
|
36370105
|
CCND2
|
CDK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
949.0
|
0.94
|
STRING
|
36370105
|
TS101
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
24244542
16189514
11943869
|
CCND3
|
CDK6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
PCNA
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
33961781
26496610
7903056
9545286
26186194
12361598
21319273
10930425
29510343
|
GA45G
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
11022036
16189514
10455148
|
CDK4
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
33961781
11463845
15169570
20102411
17556661
23443559
8242751
9106657
23543736
9632134
15232106
18850315
28514442
8756624
16189514
10022865
9464540
9658399
30833792
16962592
12383116
23007395
8622677
15695403
|
CDK2
|
CCNE1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.96
|
0.96
|
Signor
|
19561641
|
CDC6
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
967.0
|
0.96
|
STRING
|
36370105
|
CCNE2
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.96
|
STRING
|
36370105
|
DDB1
|
DTL
|
â—¼ PHYSICAL_INTERACTION
|
|
|
969.0
|
0.96
|
STRING
|
36370105
|
GA45G
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
11022036
16189514
16713569
10455148
|
PCNA
|
GA45A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
7478510
32814053
7973727
7784094
23485469
20460379
10828065
26264872
10973963
16189514
|
CDK6
|
CCND3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
33961781
16782892
11360184
21516116
8114739
26264872
23602568
14681455
32814053
9716181
16713569
32707033
33854235
27107012
32296183
17517622
15232106
30217970
28514442
25416956
16189514
26186194
29997244
|
P53
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
21317885
11839577
23201157
21316347
25312347
22975381
17369817
21084285
30005830
23443559
21465263
10980696
17936559
10488081
16845383
21149449
22366412
23483203
29549180
14741215
26673821
11713288
18665269
15058298
29524278
28514442
22510990
25241761
22525275
19106616
22467867
25954860
10889512
16595680
24998844
15848166
28628118
28362432
17116689
33650658
14499615
24980433
10608892
26876197
17438265
22103682
22374672
16055726
7689721
17363365
19411066
12167711
23318437
18566590
31796886
30244831
12944468
23261415
27215386
27826076
11178989
19223463
17301054
9724739
32894144
21075307
29121928
19305137
17318220
20659896
20080206
7686617
11744695
18467333
23246961
23150668
23776465
16215989
9223638
16331255
31968249
17908790
14702041
15094782
11278372
28605833
31647545
24200963
10601022
21454483
27893708
21088494
32516735
16861890
26238070
20705607
21887275
19303885
25609649
12915590
31406141
27282385
25156994
23671280
15358376
23609977
25168242
19071110
22991965
22653443
22920093
7926727
17470788
26908445
27856536
26475964
19857530
11709713
11714701
30532073
19411846
11094089
20173098
17591690
9582019
12552135
20542919
28205554
14704432
15001357
29876924
25417702
23880345
20124408
19033382
22487680
30598450
33061576
22575647
9131587
17159902
31152661
17297477
9271120
25384516
24659749
21261729
12529318
22411991
14671306
22084066
20395212
21986495
29487367
33355139
23802716
23370271
23946421
22083959
32807901
15154850
29670376
27905468
35140242
25283148
22085928
11562347
10640350
19098711
32901886
21726810
25624478
25637791
21584881
16870621
12690203
12612087
15824742
11572869
25464845
26203195
22157679
30454706
28082682
9809062
17302414
19085961
24567357
25362358
17080083
17426254
15242646
22524527
29295817
16751805
11431470
26882543
30097011
18604177
20591651
22948151
24462112
10827196
20479273
31533005
22389628
21170087
20694676
17666403
11597128
33503543
14596917
18332869
10321734
21857681
16579792
16414131
18264029
21071676
30464405
17989425
20234175
10681559
27308622
19816404
30355102
19805293
9824166
25313037
16173922
24926618
16159876
26540344
18541670
32904724
17616658
12842086
26720344
27129163
22266868
27031960
32528731
22737255
15604276
16432196
19188367
1614537
22914926
24842904
15247280
32097779
23252402
17347673
16964247
17310983
22331460
30584071
22032989
24240685
31652301
10435614
24621507
24361594
15308643
32334023
16547496
20639885
17139261
15933712
21478269
15313915
23402884
21750659
11112690
19255450
22124327
25277184
19234109
21965653
27336364
15122315
22916255
22262183
15295102
31092600
25512388
16713569
26001071
27807478
31940492
20588255
20174603
20570896
20708156
27886165
17056014
19081178
29547122
23572512
16905769
15542844
19941302
10561590
28542145
32066565
16212962
10202144
28549433
10734067
21572037
18172499
9363941
15550400
17380154
10892746
14559824
22227409
18316739
33495326
17234751
15280377
31177307
24127580
19160491
17290220
8875929
12381304
16857591
18813780
10347217
21561866
24413661
31066983
20847049
21098709
25103245
8058315
22807444
30832340
21268072
20962272
26350565
30175854
20591429
22444248
32427887
16023600
24667498
11351297
11285227
11223036
18784078
11384992
10562557
19568783
31138778
21925390
11486026
19597489
9450543
31665549
22318540
27106262
24207125
15950904
18223694
23728348
22474335
34362424
22912717
20047188
14612427
14517261
30679555
18815136
18061646
28394340
34408321
18309296
11046142
15144954
12897156
23776060
15210108
27811966
19357310
22391559
16338390
29899406
34040386
26186194
11284721
15908921
23652204
33765973
31626714
17848574
9529249
25739118
30879903
10766163
15013777
22588298
18981217
29755129
30320499
11070080
22301280
27543608
30948704
19590512
15558054
12867035
24488098
27462439
18485870
17268548
22819825
31591476
23826318
21471462
9278461
16866370
22659184
19166840
20660730
29269425
31239268
32198344
25543083
17875722
10196247
15053879
21084564
16107876
16678796
17098746
19656744
30109812
11925449
17525743
16624812
30455251
19153082
28553961
21132010
26578655
32874188
31903119
29997244
19837670
20837658
26883110
21060154
33961781
33579943
20235143
15064742
26556313
22745160
20657550
20484049
16152627
11697899
18234963
24314634
12208736
30320919
11713287
28223335
30252118
10722742
31594538
19483087
22266850
24643130
20959462
33020477
21988832
12426395
19332559
23169665
12620407
23134341
27249653
|
CDK2
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
33961781
23455922
11463845
24218572
11477082
20102411
26496610
9218599
12417722
12361598
16765349
23602568
23443559
29510343
8242751
17698606
20587660
10874474
13678583
9546435
10918595
11521189
11302688
10022118
9472014
9380407
9858587
27215384
9632134
15232106
12839982
11132966
25483090
18850315
8756624
25416956
28514442
16189514
9660939
9464540
15890360
12949733
17418410
9658399
29666278
30833792
16962592
24407240
12383116
9840943
25241761
12800980
10878006
23007395
26186194
24358021
31112565
8641969
8622677
9284049
15557281
15647383
|
CCND1
|
CDN1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
33961781
17556661
21516116
8657154
7478582
23443559
21654808
8242751
9106657
15681588
33854235
16082198
8662825
27107012
17420273
26203195
17081987
15232106
21988832
25416956
8756624
28514442
30833792
9823309
12383116
23007395
9837900
15695403
|
SKP1
|
CKS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
33961781
15772084
16979657
16209941
12813041
23589337
27705803
19786724
|
CCNB1
|
CDC20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
970.0
|
0.97
|
STRING
|
36370105
|
CDK6
|
CCND1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
14681455
21654808
17420273
33961781
11739795
17517622
11160398
24855949
15232106
9178893
24953629
33854235
11360184
16713569
19075005
10580009
10022865
|
SKP2
|
SKP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
33961781
20160477
16880511
19398581
18667692
17463251
34237211
27705803
23911321
22310285
15070733
19270694
27220724
26087183
9827542
22464731
31467278
18818696
24085301
10559916
30254149
29137415
23770852
30728155
10531035
12813041
15469821
20041211
18239684
16189514
28614300
29499133
12609982
9430629
33422522
34080260
16376880
11961546
32350066
23868976
11099048
22524983
10918611
10559858
15342634
23261596
15456869
26474281
22632967
16275325
29997244
15452136
|
CCNB2
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
DTL
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
CDK2
|
CCNA2
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.97
|
0.97
|
Signor
|
10652300
|
CCNA2
|
CDC20
|
â—¼ PHYSICAL_INTERACTION
|
|
|
979.0
|
0.97
|
STRING
|
36370105
|
CDK4
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
CDK5
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
CDK4
|
CCND3
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
8153045
21516116
|
CDK3
|
CKS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.98
|
0.98
|
HIPPIE
|
33961781
32296183
26186194
28514442
7809159
23602568
|
CCNB1
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
982.0
|
0.98
|
STRING
|
36370105
|
CDK2
|
CKS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
8601310
23455922
33961781
12140288
26496610
7809159
23602568
19786724
26344197
31467278
25852190
16979657
28514442
16189514
15772084
9840943
26186194
17409098
29997244
|
CDK2
|
CCNE1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
33961781
8978686
23455922
15980415
24771265
15670215
15514162
26496610
20837141
25728284
9891079
33854239
10330164
8867812
23602568
14681455
11433299
16431923
9716181
20587660
28137908
14701826
14536078
17361108
33854235
10827081
8662825
9472014
25852190
16223725
9192873
11940657
12839982
11132966
10359664
7799941
21092281
8647086
8756624
19631451
28514442
21372285
9660939
17431037
17254967
29439025
19470470
21241890
9840943
17970072
1388288
18559665
12800980
15004009
26186194
24358021
23853094
12529437
15557281
|
CCND3
|
CDK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
991.0
|
0.99
|
STRING
|
36370105
|
CDK2
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
992.0
|
0.99
|
STRING
|
36370105
|
CCND1
|
CDK4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
MDM2
|
MDM4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
CUL4A
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
CCNA2
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
CCNB1
|
CDK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
CCNE1
|
CDK2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
PCNA
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
10858306
11756412
11948190
12637553
14624239
14726013
15703371
15871698
16442856
16697054
16731526
17088286
17116881
18087292
18584027
18809224
19208614
19364882
1974050
19748837
19772495
19847258
20056333
20478261
20510258
20603072
21251944
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PCNA
|
DDB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17720710
12226657
18342608
20129063
|
PCNA
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
17720710
12226657
18342608
20129063
|
PCNA
|
PARP1
|
â—¼ SHARES_COMPLEX
|
|
|
43.0
|
1.0
|
ACSN
|
10858306
11756412
11948190
12637553
14624239
14726013
15703371
15871698
16442856
16697054
16731526
17088286
17116881
18087292
18584027
18809224
19208614
19364882
1974050
19748837
19772495
19847258
20056333
20478261
20510258
20603072
21251944
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
STAT3
|
CCND3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16084951
18310224
15184887
|
CCND3
|
CDK6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
17517622
8114739
26186194
27107012
23602568
10477583
16782892
21516116
25416956
29997244
31515488
32814053
15232106
32296183
11360184
16713569
9716181
|
CCND3
|
CDK4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
43.0
|
1.0
|
Omnipath
|
11896535
25416956
16985050
34591612
21988832
14597415
17517622
16782892
10342870
21516116
23880157
15232106
16189514
11360184
26496610
25910212
26186194
27107012
10477583
19237555
32296183
14641107
9106657
9508775
31515488
9716181
|
DDB1
|
CUL4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18931676
19270156
19557001
19622404
19686080
19809470
19847258
20211143
|
DDB1
|
CUL4A
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
11900249
12648680
12820959
15071497
15340381
15459660
15688063
1570337
15703371
16697054
17884153
18931676
19270156
19557001
19622404
19686080
19809470
19847258
20211143
|
DTL
|
CUL4A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
21145461
19231300
16949367
|
CCNA1
|
CDC6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
7575488
18590585
17296725
17303408
17102137
17116885
19793801
17582221
17660363
15279786
|
CDC20
|
CCNA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
15577895
10679238
18471975
15840442
25669885
|
CDK2
|
CCNA2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
81.0
|
1.0
|
Omnipath
|
8756328
7553852
11377199
17145710
23602568
11983168
12044161
19483727
12853968
16209941
8397207
15455144
19631451
8475101
24358021
15557281
8684460
12941338
15647383
15890360
21447625
9380407
26496610
11141566
25852190
15189033
14656438
20733051
21241890
10652300
25669885
12244298
26186194
10930425
9660939
10477583
24302728
15239650
19773423
8463339
16290148
10924145
11907280
17361108
17254966
8662825
15828833
18471975
9724724
7630397
10559988
9716181
11940657
23455922
|
CCNA2
|
CDC6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
9889196
10339564
9566895
|
CCNA2
|
CDK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17145710
1833185
10924145
8423786
|
CDK1
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
38.0
|
1.0
|
Omnipath
|
17145710
23799914
34224728
20117088
16784539
24358021
24508230
19470789
10973963
17283331
20228808
18347064
11242082
12397081
10362260
24582498
15582998
20367638
1833185
12447691
9001210
2570636
24101512
23543736
11331587
12524548
22726437
27626412
|
CDC20
|
CCNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
19652693
18590585
7575488
17303408
12124778
17660363
15279786
15917306
|
STAT3
|
CCND1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
16510571
19880237
17997399
15469392
16651438
21163886
22566696
16912181
22349830
16384639
12147685
21344490
20160059
19506034
20332458
23329648
11114718
17761947
22218594
15994929
21172343
18988190
18177723
24499623
21435102
19926637
18184402
17344214
22313388
23950841
|
CCND1
|
CDK4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
63.0
|
1.0
|
Omnipath
|
26203195
17145710
8978686
12036906
23562856
25416956
16985050
23707388
19767775
9837900
17517622
19237565
9372967
25502805
23718855
9228064
7736585
15232106
11360184
20837141
21306487
25910212
25241761
27107012
9150368
18537972
9178893
31217276
8867812
10580009
23007395
11160398
19470470
19075005
9106657
8259215
10908655
8756624
23543736
24855949
7568034
24218572
8662825
31515488
17205132
|
CCND1
|
CDK6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
19075005
17517622
9178893
11739795
24855949
15232106
16713569
11360184
10580009
11160398
|
CCND2
|
CDK6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
10477583
17517622
16713569
|
CCND2
|
CDK4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
25910212
17517622
27107012
11896535
10477583
9325318
31515488
16189514
32296183
|
CCNE1
|
SKP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
16209941
10375532
15199159
11231585
|
SKP1
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
19847258
19686080
19270156
17884153
19622404
15703371
12648680
11900249
16697054
18931676
19809470
15459660
|
SKP2
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
14.0
|
1.0
|
Omnipath
|
19847258
19686080
19270156
17884153
19622404
15703371
11237742
12648680
11900249
16697054
18931676
19809470
15459660
|
CDK2
|
CCNE1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
50.0
|
1.0
|
Omnipath
|
17145710
16223725
21092281
15004009
10962581
9840943
8643455
24358021
8861947
21372285
17570479
11237742
10330164
22558078
10652300
19561641
10477583
18691976
23853094
12144826
10500095
1388288
10827081
17970072
28137908
19470470
8756624
10809788
14536078
15364936
|
CCNE2
|
SKP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
16209941
10375532
15199159
11231585
|
CCNE2
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
16209941
10375532
15199159
11231585
|
SKP2
|
CCNE2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
19847258
19686080
19270156
17884153
19622404
15703371
12648680
11900249
16697054
18931676
19809470
15459660
|
SKP1
|
CCNE2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
19847258
19686080
19270156
17884153
19622404
15703371
12648680
11900249
16697054
18931676
19809470
15459660
|
CDK1
|
CDC20
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
22.0
|
1.0
|
ACSN
|
12124778
14551205
14614141
15242590
15279786
15375219
15377654
15485915
15917306
16713580
16818604
17303408
17596790
17660363
18414028
18543256
18590585
18995830
19652693
19686080
7575488
9892021
|
CDK1
|
CDC6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
ACSN
|
14551205
15279786
17102137
17116885
17296725
17303408
17582221
17660363
18414028
18590585
19793801
7575488
|
CDK2
|
CDC6
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
14536078
15147722
15175241
15279786
15677884
16581787
17038621
17102137
17116885
17296725
17303408
17582221
17660363
17713585
18590585
18636226
19793801
7575488
|
CDK2
|
CDC6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
42.0
|
1.0
|
Omnipath
|
17303408
23129444
19793801
15279786
7575488
20068231
17116885
17582221
17570479
9889196
27207654
16153703
18590585
29760377
18691976
10339564
14749377
19343071
17660363
16707497
17296725
24216307
23479742
17102137
15212693
|
CDK1
|
MDM4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
15735705
|
SKP1
|
CDK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
7553852
23602568
16979657
9636170
26496610
25852190
|
CDK2
|
SKP2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
7553852
20160477
23602568
25271736
18239684
28446188
23226679
10386600
19270695
26496610
16189514
25852190
26186194
25788262
9858587
22770219
15355997
10559858
23807222
22311674
16979657
9636170
19686743
19270694
18604603
23455922
|
STAT3
|
CDK5
|
â—¼ PHYSICAL_INTERACTION
|
|
|
34.0
|
1.0
|
ACSN
|
10347215
12223527
12947387
14607900
14670306
15218058
15356132
15573129
16418395
16697054
18776941
19380816
19473888
19595721
19596235
19596236
19686080
19772495
19847258
20093776
20237412
20406969
20581311
21840487
21922195
23124025
23454751
23589330
23850759
23953057
24857661
27216177
28186502
7543512
|
STAT3
|
CDK5
|
â—¼ SHARES_COMPLEX
|
|
|
34.0
|
1.0
|
ACSN
|
10347215
12223527
12947387
14607900
14670306
15218058
15356132
15573129
16418395
16697054
18776941
19380816
19473888
19595721
19596235
19596236
19686080
19772495
19847258
20093776
20237412
20406969
20581311
21840487
21922195
23124025
23454751
23589330
23850759
23953057
24857661
27216177
28186502
7543512
|
CDK5
|
PARP1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
12556884
16332722
16858402
17303408
19151707
20724832
21727086
21922195
23589330
23850759
|
CDK5
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
25038288
16651438
19156541
12763138
28114390
16879821
23941877
15096606
26198700
|
HDAC1
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
51.0
|
1.0
|
ACSN
|
10721693
11283614
11715018
11779693
11923280
12545156
12668723
14761977
15024084
15140942
15151915
15155580
15169778
15465827
15574337
15876864
16232121
17055429
17110379
17158541
17508028
17550342
17823410
19448627
19459846
20027199
20066118
20182602
20457558
20506250
20679392
20713526
20818389
21234400
21336307
21340684
21483453
21518799
21733352
21764762
2191300
21919891
22102694
22370643
22754780
22796940
23140366
23869868
6396087
9450543
9618481
|
HDAC1
|
MDM2
|
â—¼ SHARES_COMPLEX
|
|
|
51.0
|
1.0
|
ACSN
|
10721693
11283614
11715018
11779693
11923280
12545156
12668723
14761977
15024084
15140942
15151915
15155580
15169778
15465827
15574337
15876864
16232121
17055429
17110379
17158541
17508028
17550342
17823410
19448627
19459846
20027199
20066118
20182602
20457558
20506250
20679392
20713526
20818389
21234400
21336307
21340684
21483453
21518799
21733352
21764762
2191300
21919891
22102694
22370643
22754780
22796940
23140366
23869868
6396087
9450543
9618481
|
HDAC1
|
MDM2
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
51.0
|
1.0
|
ACSN
|
10721693
11283614
11715018
11779693
11923280
12545156
12668723
14761977
15024084
15140942
15151915
15155580
15169778
15465827
15574337
15876864
16232121
17055429
17110379
17158541
17508028
17550342
17823410
19448627
19459846
20027199
20066118
20182602
20457558
20506250
20679392
20713526
20818389
21234400
21336307
21340684
21483453
21518799
21733352
21764762
2191300
21919891
22102694
22370643
22754780
22796940
23140366
23869868
6396087
9450543
9618481
|
MDM2
|
MDM4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
69.0
|
1.0
|
Omnipath
|
17145710
10218570
17616658
16511560
22266850
12874296
21925390
25825738
21988832
25512388
16227609
22493164
22902369
25659040
18219319
12963717
15604276
18566590
12370303
19838211
26359458
27617579
25809483
34551723
10608892
23028042
22120712
25703327
12860999
32300648
16055726
24813712
17301054
12483531
23671280
17159902
27621617
25105592
20484049
20724842
27215386
10827196
26001071
11606419
23946421
19683495
20705607
24755078
25384516
20473904
12393902
|
SKP1
|
SKP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
19.0
|
1.0
|
ACSN
|
11516665
11900249
12648680
12820959
15071497
15147722
15340381
15459660
15668399
15688063
15703371
16697054
17884153
18931676
19270156
19622404
19686080
19809470
19847258
|
SKP1
|
SKP2
|
â—¼ SHARES_COMPLEX
|
|
|
19.0
|
1.0
|
ACSN
|
11516665
11900249
12648680
12820959
15071497
15147722
15340381
15459660
15668399
15688063
15703371
16697054
17884153
18931676
19270156
19622404
19686080
19809470
19847258
|
PARP1
|
PARP1
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-7.28
|
7.27
|
PKG
|
28854368
|