Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
HDAC1 PCNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18691180 9650586
PCNA CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16713569 9667749
PCNA CCND3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16189514 7908906
CDK6 CCND3 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
CCND3 CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16609025
PARP1 CUL4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
CCNB2 CCNE2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001737 24358021
HDAC1 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20049841 20821348
STAT3 CCND1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11279133
CCND1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11279133
CDK4 CCND2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20156660 27107012
SKP1 CDC20 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12791267 10023660
STAT3 CDK4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22218594
PARP1 DDB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
MDM2 MDM4 â—¼   COLOCALIZATION 2.0 0.8 intact 17159902 5219425
SKP2 SKP1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
CCNA2 PCNA â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
CCND1 CDK1 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
CDK1 CCNA1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 14681455 8565853 16009130 1628647 7799941
CDK2 P53 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 10884347 10747897 12064478 10348343 25241761 19556892
CDC6 CDN1A â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 25241761 15232106
CDN1A UBP11 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 29666278 23443559
CDN1A HDAC1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 25241761 20154723 16082198
SKP1 CDN1A â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 16376880 25241761 27215384
DDB1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 24249678 26679995 25189618 34026424
CCNE1 PCNA â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
CUL4A SKP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22474075 21145461
GA45A GA45G â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11498536 16189514
P53 PSMD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 32807901 22653443
P53 SKP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 23443559 22653443
CDN1A TBA1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21900206 23443559
CDN1A DOCK7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21900206 23443559
PSMD2 CDN1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18086887 29777785
CKS1 CCNE2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CKS1 CCNE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CDK2 CDK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 21319273
PSMD2 MDM2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20479273 18086887
CDC20 CDK1 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
PCNA CCNE1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PCNA CCNE2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CDN1A CUL4A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26613412 30945288 18794347
CCNA2 CCNA1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
GA45G CCNB1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12124778
KITH P53 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21900206 16169070 16713569 32807901
TS101 MDM2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11172000 17060450
CDN1A DDB1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 18703516 18794347 23443559
PSME3 CDN1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27215384 21445096 17588519
CDC20 CKS1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15014502 28514442 33961781
CDK5 CCND1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28514442 23455922 33961781 21654808
CDK5 CCNE1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28514442 23455922 23602568 33961781
SKP2 CDC20 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 20663873 26811472 15014502 28514442 25306918
CDK1 CDK3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CDK5 CDK14 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CCND3 CDK1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
PCNA CCNB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28514442 8101826 33961781 7903056
TS101 P53 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11172000 16713569 16189514
CDK4 P53 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28218424 28205554 28628118
MDM4 CDN1A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 18086887 21148311
CCNE1 CDK4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9716181 28205554 28628118
CCNE1 CDK6 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 9716181 28205554 28628118
CDK1 CDC20 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28514442 26912231 10799291
CCNA1 SKP2 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
HDAC1 STAT3 â—¼   PHYSICAL_INTERACTION 845.0 0.84 STRING 36370105
P53 CCNA2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10884347 16713569
CDN1A CSK2B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10679299 16713569
CCNB2 CDN1A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 15232106
CDN1A STAT3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25241761 10764767 16189514
CDC20 CDN1A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 30833792 17679094 33751805 23443559
CDN1A CKS1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 30833792 23443559
CDK6 PCNA â—¼   PHYSICAL_INTERACTION 856.0 0.85 STRING 36370105
CDN1A MKRN1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 34504644 19536131
SKP1 CCNA2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 9858587 33422522 26496610 16209941
CDK2 CDC6 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10339564 9566895 9889196
CDK1 CDC6 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10339564 21041660
PARP1 HDAC1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19470756 34079125 16204234 20596014
CCNA1 CDK1 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
CDK1 SKP2 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
P53 MKRN1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19536131 31367258
SET CDN1A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12407107 16474839 16189514 27626385
CDN1A MDM2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20086099 17373842 14761977 25241761 20308078 14633995
CDK5 CCNA2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 23455922 33961781
CDC20 CCNB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 23239745 20383333 25161877 31230944 20080579 25306923 10799291 20733055 25482201 23091007 32152539 19820702 25825779 22014574 12956947 24151075 23007861 17360335 22193957 19826003 26912231 14701726 23791783 27522463 25246557 31455778 18471975 23288039 23979597 11562349 26387737 33082289 11804586 25505175
CCNE2 CDK3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26186194 9840943
CDK2 CDC20 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 23455922 26811472 25852190 28514442
CDK5 CDK3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25852190 23455922 33961781 28514442
CDK3 SKP2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 23602568 26186194
CCND2 CDK5 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CDC20 SKP2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CDK2 SKP1 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CCNE2 PCNA â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
PCNA CCND3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 16189514 7908906
DTL CUL4A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 30649446 17041588 21145461 16861906 21628527 31155351 16949367 30623174 29424068 23478441 31973889 23555860
UBP11 P53 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19615732 33567341 25471832 34141823
CDK1 CDN1A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 24218572 30833792 17679094 26496610 26186194 32707033 21308745 28514442 23602568 11559705 23543736
KITH CDN1A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11389691 16189514
CKS1 CCNA2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 33422522 18471975 26496610 11907280 16209941 19483727 26186194 28514442
CDK5 CCNB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 23455922 25852190 26186194 28514442 23602568 32707033
CCNB1 CDK3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 27030811 28514442
CDK4 CDK6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 23455922 28205554 28628118
CDK5 CCND3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 23455922 32296183 26186194 28514442 23602568
PSME3 P53 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21084564 18309296
P53 CDN1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12897156 17371838 33149608 11896572 16616141 25241761 27626385 21900206 9121469 33503543
P53 HDAC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14976551 20075864 17827154 19011633 10521394 16697957 10777477 16107876 11099047 32494626 16959611 11313951 12426395 18765668 22266186 19303885 25241761 26539911 20633551
CDK5 CDN1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 15890360 23455922 30833792 23602568 23443559
CDK3 CDN1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 24218572 32296183 9811456 26186194 28514442 23602568 23443559
CDN1A DTL â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18703516 21628527 20606006 18794347 23213251
SKP2 CDN1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 17477906 15980415 30833792 17679094 16376880 13678583 25241761 19686743 32035614 23261596 18794347
PARP1 CDN1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23169665 20303835 20302655 12930846
CDK6 CDN1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 20102411 15232106 16713569 28514442 16189514 10022865
CCNB1 CDN1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 30833792 17679094 25241761 15251430 23443559 11559705 16082198 8662825
PSA3 CDN1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20086099 20308078 16713569 11350925 16189514
CKS1 CCNB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 30674583 18471975 26496610 28514442 19786724
CDC20 CCNA2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26496610 23007648 26960431 19098431 25669885 20733051 25750436 32152539 25306918 19483727 28514442 19826003 10679238 27522463 26811472 31455778 32307883 18471975 26186194
CDK1 CCNA2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14681455 33961781 33422522 17679094 25852190 26496610 24302728 19483727 12853968 26186194 21308745 8463339 28514442 9053846 23602568 32707033
CDC6 CCNA2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9566895 10339564 9889196
SKP2 CCNE1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11237742 22959436 10790373
CCND1 CDK2 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
HDAC1 PCNA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14988403 11929879 16189514 16713569
PCNA CDN1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20605778 11463845 25502805 33961781 26496610 9545252 11254741 30301766 11559705 23443559 29510343 9465025 26272819 16616141 16474839 9546435 7911228 22383522 17588519 16510448 8861913 11350925 16082198 11302688 8662825 7780738 19895794 8861969 10022118 27107012 32296183 25411249 15576034 30217970 7915843 19704162 18086887 21988832 11313979 10873631 25416956 28514442 16189514 23223023 21415862 30833792 20606006 31112565 12964161 26186194 30623174 17115032 12930846
PCNA CCND1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21654808 8101826 33961781 7903056 7908906 15681588
PCNA DTL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16861906 25154416 21725088 30301766 30623174 29424068 20129063
PCNA CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10930425
CCND3 CDN1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28514442 27107012 33961781 32296183 30833792 25416956 9716181 23880157 25241761 26496610 15232106 30217970 26186194 21988832 8756624 16189514 23443559
CCNA1 CDN1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 32814053 10022926 12383116 16009130 15232106 16982699 25241761 26264872 8756624 16189514 7478582 29997244
CDK5 P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12064478 10884347 17591690 11483158
MDM4 P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 31462704 10827196 19255450 22745160 23671280 31066983 10075736 10629057 11528400 15604276 24445145 19521340 19075013 12370303 30598450 21965653 19432880 16024788 31152661 21088494 22807444 17301054 30832340 17875722 16713569 20724842 28628118 16227609 30672125 25464845 25825738 22266850 24659749 20515689 21075307 20174603 18316739 17110929 20705607 10608892 24127580 29023092 26876197 24667498 9226370 18677113 27114532 28514442 22374672 17080083 8895579 12393902 29523541 32511789 30045945 19305137 23028042 18485870 11223036 26148237 25609649 19153082 26186194 21925390 28205554 23946421 28487147 15916963 12874296 25961923 27249653
P53 PARP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12898523 14627987 9565608 32807901 16713569 9312059 23169665 15044383
CDN1A CCND2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28514442 27107012 33961781 32296183 15169570 9823309 25416956 25241761 11971966 30217970 26186194 8756624 16765349 16189514 23443559 10022865
GA45A CDN1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10912791 7478594 10973963 16189514 16772293
CDN1A CDK14 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17517622 26186194 28514442 23602568
CCNE1 CDN1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 11477082 24771265 9218599 16765349 23443559 8242751 9716181 13678583 8662825 9472014 9380407 9632134 12839982 21988832 8756624 9660939 30833792 17293600 8891332 25241761
BCCIP CDN1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14726710 10878006 19713748
CCNE2 CDN1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 9840927 30833792 9840943 26496610 15232106 26186194 24358021 28514442 23443559
CCNA2 CDN1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28514442 15890360 9380407 8242751 33961781 30833792 17679094 9632134 26496610 26186194 21308745 8756624 12947099 9660939 23443559 8662825
SKP2 CKS1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 12140288 15980415 11463388 19786724 11231585 23589337 12529174 16979657 16209941 12813041 28514442 18239684 16189514 33422522 15772084 16338391 17409098 18519678
CKS1 CDK1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 26344197 25852190 18471975 22939629 9774639 26496610 26186194 32707033 25416956 23602568 19786724
SKP2 CCNA2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 20160477 33989513 9858587 33422522 24632684 15355997 7553852 26496610 16209941 27720894 31181401 26186194 10559858 28514442 18604603
SKP2 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9858587 15355997 33989513
CCNA2 SKP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9858587 15355997 33989513
CDK6 CCND2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 16189514 9178893 30217970 11360184 28205554 16713569 28628118 23602568 11358847 10022865
STAT3 CCND2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24287565 12147685
STAT3 CCNE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22583478 19049964 19010822
SKP2 CDK2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 20160477 23455922 26496610 22770219 23602568 7553852 9636170 9858587 15355997 25852190 10386600 16979657 28514442 16189514 18604603 33422522 19686743 19270695 26186194 10559858
MDM4 MDM2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 26720344 33961781 27621617 26359458 10827196 10629057 24755078 23671280 22902369 22745160 22333590 15604276 20484049 18566590 12370303 30598450 31796886 10218570 19432880 34551723 12483531 29524278 17159902 27777309 12860999 27215386 11606419 18219319 17301054 19683495 25512388 20724842 28628118 16227609 22493164 20473904 25384516 26001071 25825738 22266850 29057323 25809483 25703327 32427989 20705607 10608892 31024344 19619542 21988832 29262653 25659040 29523541 28514442 27617579 29295817 33985974 12393902 16055726 23028042 24813712 22120712 32300648 32075226 21925390 17616658 28205554 23946421 19838211 25105592 12874296 25961923
PSME3 MDM2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21084564 18309296 24583282
CCNA2 SKP2 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
CCND2 CDK2 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
CCND3 CDK2 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
GA45A CCNB1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 12124778 10362260
CDK2 SKP2 â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
CCNB2 CDK2 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
CDC20 CDK2 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
CCND1 CDK6 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
CKS1 CCNB2 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 33961781 28514442 19786724
CCNE1 CDK1 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
CCNA2 CDK1 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
CUL4A DTL â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
CDC20 CCNA1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 19477924 10679238
MDM4 MDM2 â—¼   COLOCALIZATION ✅ 0.93 0.93 mint 17159902 5219425
CCNA1 CDK2 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CCND2 CDK6 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
CDK2 CDK3 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 28514442 23455922 26186194 33961781
CDK2 CDC6 â—¼   PHOSPHORYLATION ✅ - 0.94 0.94 Signor 10339564
CCNA2 CDC6 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
CCND2 CDK4 â—¼   PHYSICAL_INTERACTION 949.0 0.94 STRING 36370105
TS101 CDN1A â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 24244542 16189514 11943869
CCND3 CDK6 â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
PCNA CDK2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 28514442 33961781 26496610 7903056 9545286 26186194 12361598 21319273 10930425 29510343
GA45G CDN1A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 11022036 16189514 10455148
CDK4 CDN1A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 11463845 15169570 20102411 17556661 23443559 8242751 9106657 23543736 9632134 15232106 18850315 28514442 8756624 16189514 10022865 9464540 9658399 30833792 16962592 12383116 23007395 8622677 15695403
CDK2 CCNE1 â—¼   PHOSPHORYLATION ✅ - 0.96 0.96 Signor 19561641
CDC6 CDK2 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
CCNE2 CDK2 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
DDB1 DTL â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
GA45G PCNA â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11022036 16189514 16713569 10455148
PCNA GA45A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 7478510 32814053 7973727 7784094 23485469 20460379 10828065 26264872 10973963 16189514
CDK6 CCND3 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 16782892 11360184 21516116 8114739 26264872 23602568 14681455 32814053 9716181 16713569 32707033 33854235 27107012 32296183 17517622 15232106 30217970 28514442 25416956 16189514 26186194 29997244
P53 MDM2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21317885 11839577 23201157 21316347 25312347 22975381 17369817 21084285 30005830 23443559 21465263 10980696 17936559 10488081 16845383 21149449 22366412 23483203 29549180 14741215 26673821 11713288 18665269 15058298 29524278 28514442 22510990 25241761 22525275 19106616 22467867 25954860 10889512 16595680 24998844 15848166 28628118 28362432 17116689 33650658 14499615 24980433 10608892 26876197 17438265 22103682 22374672 16055726 7689721 17363365 19411066 12167711 23318437 18566590 31796886 30244831 12944468 23261415 27215386 27826076 11178989 19223463 17301054 9724739 32894144 21075307 29121928 19305137 17318220 20659896 20080206 7686617 11744695 18467333 23246961 23150668 23776465 16215989 9223638 16331255 31968249 17908790 14702041 15094782 11278372 28605833 31647545 24200963 10601022 21454483 27893708 21088494 32516735 16861890 26238070 20705607 21887275 19303885 25609649 12915590 31406141 27282385 25156994 23671280 15358376 23609977 25168242 19071110 22991965 22653443 22920093 7926727 17470788 26908445 27856536 26475964 19857530 11709713 11714701 30532073 19411846 11094089 20173098 17591690 9582019 12552135 20542919 28205554 14704432 15001357 29876924 25417702 23880345 20124408 19033382 22487680 30598450 33061576 22575647 9131587 17159902 31152661 17297477 9271120 25384516 24659749 21261729 12529318 22411991 14671306 22084066 20395212 21986495 29487367 33355139 23802716 23370271 23946421 22083959 32807901 15154850 29670376 27905468 35140242 25283148 22085928 11562347 10640350 19098711 32901886 21726810 25624478 25637791 21584881 16870621 12690203 12612087 15824742 11572869 25464845 26203195 22157679 30454706 28082682 9809062 17302414 19085961 24567357 25362358 17080083 17426254 15242646 22524527 29295817 16751805 11431470 26882543 30097011 18604177 20591651 22948151 24462112 10827196 20479273 31533005 22389628 21170087 20694676 17666403 11597128 33503543 14596917 18332869 10321734 21857681 16579792 16414131 18264029 21071676 30464405 17989425 20234175 10681559 27308622 19816404 30355102 19805293 9824166 25313037 16173922 24926618 16159876 26540344 18541670 32904724 17616658 12842086 26720344 27129163 22266868 27031960 32528731 22737255 15604276 16432196 19188367 1614537 22914926 24842904 15247280 32097779 23252402 17347673 16964247 17310983 22331460 30584071 22032989 24240685 31652301 10435614 24621507 24361594 15308643 32334023 16547496 20639885 17139261 15933712 21478269 15313915 23402884 21750659 11112690 19255450 22124327 25277184 19234109 21965653 27336364 15122315 22916255 22262183 15295102 31092600 25512388 16713569 26001071 27807478 31940492 20588255 20174603 20570896 20708156 27886165 17056014 19081178 29547122 23572512 16905769 15542844 19941302 10561590 28542145 32066565 16212962 10202144 28549433 10734067 21572037 18172499 9363941 15550400 17380154 10892746 14559824 22227409 18316739 33495326 17234751 15280377 31177307 24127580 19160491 17290220 8875929 12381304 16857591 18813780 10347217 21561866 24413661 31066983 20847049 21098709 25103245 8058315 22807444 30832340 21268072 20962272 26350565 30175854 20591429 22444248 32427887 16023600 24667498 11351297 11285227 11223036 18784078 11384992 10562557 19568783 31138778 21925390 11486026 19597489 9450543 31665549 22318540 27106262 24207125 15950904 18223694 23728348 22474335 34362424 22912717 20047188 14612427 14517261 30679555 18815136 18061646 28394340 34408321 18309296 11046142 15144954 12897156 23776060 15210108 27811966 19357310 22391559 16338390 29899406 34040386 26186194 11284721 15908921 23652204 33765973 31626714 17848574 9529249 25739118 30879903 10766163 15013777 22588298 18981217 29755129 30320499 11070080 22301280 27543608 30948704 19590512 15558054 12867035 24488098 27462439 18485870 17268548 22819825 31591476 23826318 21471462 9278461 16866370 22659184 19166840 20660730 29269425 31239268 32198344 25543083 17875722 10196247 15053879 21084564 16107876 16678796 17098746 19656744 30109812 11925449 17525743 16624812 30455251 19153082 28553961 21132010 26578655 32874188 31903119 29997244 19837670 20837658 26883110 21060154 33961781 33579943 20235143 15064742 26556313 22745160 20657550 20484049 16152627 11697899 18234963 24314634 12208736 30320919 11713287 28223335 30252118 10722742 31594538 19483087 22266850 24643130 20959462 33020477 21988832 12426395 19332559 23169665 12620407 23134341 27249653
CDK2 CDN1A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 23455922 11463845 24218572 11477082 20102411 26496610 9218599 12417722 12361598 16765349 23602568 23443559 29510343 8242751 17698606 20587660 10874474 13678583 9546435 10918595 11521189 11302688 10022118 9472014 9380407 9858587 27215384 9632134 15232106 12839982 11132966 25483090 18850315 8756624 25416956 28514442 16189514 9660939 9464540 15890360 12949733 17418410 9658399 29666278 30833792 16962592 24407240 12383116 9840943 25241761 12800980 10878006 23007395 26186194 24358021 31112565 8641969 8622677 9284049 15557281 15647383
CCND1 CDN1A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 17556661 21516116 8657154 7478582 23443559 21654808 8242751 9106657 15681588 33854235 16082198 8662825 27107012 17420273 26203195 17081987 15232106 21988832 25416956 8756624 28514442 30833792 9823309 12383116 23007395 9837900 15695403
SKP1 CKS1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 15772084 16979657 16209941 12813041 23589337 27705803 19786724
CCNB1 CDC20 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
CDK6 CCND1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 14681455 21654808 17420273 33961781 11739795 17517622 11160398 24855949 15232106 9178893 24953629 33854235 11360184 16713569 19075005 10580009 10022865
SKP2 SKP1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 20160477 16880511 19398581 18667692 17463251 34237211 27705803 23911321 22310285 15070733 19270694 27220724 26087183 9827542 22464731 31467278 18818696 24085301 10559916 30254149 29137415 23770852 30728155 10531035 12813041 15469821 20041211 18239684 16189514 28614300 29499133 12609982 9430629 33422522 34080260 16376880 11961546 32350066 23868976 11099048 22524983 10918611 10559858 15342634 23261596 15456869 26474281 22632967 16275325 29997244 15452136
CCNB2 CDK1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
DTL PCNA â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
CDK2 CCNA2 â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 10652300
CCNA2 CDC20 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
CDK4 PCNA â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CDK5 PCNA â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
CDK4 CCND3 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 8153045 21516116
CDK3 CKS1 â—¼   PHYSICAL_INTERACTION 0.98 0.98 HIPPIE 33961781 32296183 26186194 28514442 7809159 23602568
CCNB1 CDK2 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
CDK2 CKS1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 8601310 23455922 33961781 12140288 26496610 7809159 23602568 19786724 26344197 31467278 25852190 16979657 28514442 16189514 15772084 9840943 26186194 17409098 29997244
CDK2 CCNE1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 8978686 23455922 15980415 24771265 15670215 15514162 26496610 20837141 25728284 9891079 33854239 10330164 8867812 23602568 14681455 11433299 16431923 9716181 20587660 28137908 14701826 14536078 17361108 33854235 10827081 8662825 9472014 25852190 16223725 9192873 11940657 12839982 11132966 10359664 7799941 21092281 8647086 8756624 19631451 28514442 21372285 9660939 17431037 17254967 29439025 19470470 21241890 9840943 17970072 1388288 18559665 12800980 15004009 26186194 24358021 23853094 12529437 15557281
CCND3 CDK4 â—¼   PHYSICAL_INTERACTION 991.0 0.99 STRING 36370105
CDK2 PCNA â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
CCND1 CDK4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MDM2 MDM4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CUL4A DDB1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CCNA2 CDK2 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CCNB1 CDK1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CCNE1 CDK2 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
PCNA PARP1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PCNA DDB1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
PCNA CUL4A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
PCNA PARP1 â—¼   SHARES_COMPLEX 43.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
STAT3 CCND3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16084951 18310224 15184887
CCND3 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17517622 8114739 26186194 27107012 23602568 10477583 16782892 21516116 25416956 29997244 31515488 32814053 15232106 32296183 11360184 16713569 9716181
CCND3 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 11896535 25416956 16985050 34591612 21988832 14597415 17517622 16782892 10342870 21516116 23880157 15232106 16189514 11360184 26496610 25910212 26186194 27107012 10477583 19237555 32296183 14641107 9106657 9508775 31515488 9716181
DDB1 CUL4A â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
DDB1 CUL4A â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11900249 12648680 12820959 15071497 15340381 15459660 15688063 1570337 15703371 16697054 17884153 18931676 19270156 19557001 19622404 19686080 19809470 19847258 20211143
DTL CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 21145461 19231300 16949367
CCNA1 CDC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 7575488 18590585 17296725 17303408 17102137 17116885 19793801 17582221 17660363 15279786
CDC20 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 15577895 10679238 18471975 15840442 25669885
CDK2 CCNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 81.0 1.0 Omnipath 8756328 7553852 11377199 17145710 23602568 11983168 12044161 19483727 12853968 16209941 8397207 15455144 19631451 8475101 24358021 15557281 8684460 12941338 15647383 15890360 21447625 9380407 26496610 11141566 25852190 15189033 14656438 20733051 21241890 10652300 25669885 12244298 26186194 10930425 9660939 10477583 24302728 15239650 19773423 8463339 16290148 10924145 11907280 17361108 17254966 8662825 15828833 18471975 9724724 7630397 10559988 9716181 11940657 23455922
CCNA2 CDC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 9889196 10339564 9566895
CCNA2 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 1833185 10924145 8423786
CDK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23799914 34224728 20117088 16784539 24358021 24508230 19470789 10973963 17283331 20228808 18347064 11242082 12397081 10362260 24582498 15582998 20367638 1833185 12447691 9001210 2570636 24101512 23543736 11331587 12524548 22726437 27626412
CDC20 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 19652693 18590585 7575488 17303408 12124778 17660363 15279786 15917306
STAT3 CCND1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 16510571 19880237 17997399 15469392 16651438 21163886 22566696 16912181 22349830 16384639 12147685 21344490 20160059 19506034 20332458 23329648 11114718 17761947 22218594 15994929 21172343 18988190 18177723 24499623 21435102 19926637 18184402 17344214 22313388 23950841
CCND1 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 26203195 17145710 8978686 12036906 23562856 25416956 16985050 23707388 19767775 9837900 17517622 19237565 9372967 25502805 23718855 9228064 7736585 15232106 11360184 20837141 21306487 25910212 25241761 27107012 9150368 18537972 9178893 31217276 8867812 10580009 23007395 11160398 19470470 19075005 9106657 8259215 10908655 8756624 23543736 24855949 7568034 24218572 8662825 31515488 17205132
CCND1 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 19075005 17517622 9178893 11739795 24855949 15232106 16713569 11360184 10580009 11160398
CCND2 CDK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10477583 17517622 16713569
CCND2 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 25910212 17517622 27107012 11896535 10477583 9325318 31515488 16189514 32296183
CCNE1 SKP1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16209941 10375532 15199159 11231585
SKP1 CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 19847258 19686080 19270156 17884153 19622404 15703371 12648680 11900249 16697054 18931676 19809470 15459660
SKP2 CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 19847258 19686080 19270156 17884153 19622404 15703371 11237742 12648680 11900249 16697054 18931676 19809470 15459660
CDK2 CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 50.0 1.0 Omnipath 17145710 16223725 21092281 15004009 10962581 9840943 8643455 24358021 8861947 21372285 17570479 11237742 10330164 22558078 10652300 19561641 10477583 18691976 23853094 12144826 10500095 1388288 10827081 17970072 28137908 19470470 8756624 10809788 14536078 15364936
CCNE2 SKP1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16209941 10375532 15199159 11231585
CCNE2 SKP2 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 16209941 10375532 15199159 11231585
SKP2 CCNE2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 19847258 19686080 19270156 17884153 19622404 15703371 12648680 11900249 16697054 18931676 19809470 15459660
SKP1 CCNE2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 19847258 19686080 19270156 17884153 19622404 15703371 12648680 11900249 16697054 18931676 19809470 15459660
CDK1 CDC20 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17596790 17660363 18414028 18543256 18590585 18995830 19652693 19686080 7575488 9892021
CDK1 CDC6 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 14551205 15279786 17102137 17116885 17296725 17303408 17582221 17660363 18414028 18590585 19793801 7575488
CDK2 CDC6 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
CDK2 CDC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 42.0 1.0 Omnipath 17303408 23129444 19793801 15279786 7575488 20068231 17116885 17582221 17570479 9889196 27207654 16153703 18590585 29760377 18691976 10339564 14749377 19343071 17660363 16707497 17296725 24216307 23479742 17102137 15212693
CDK1 MDM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 15735705
SKP1 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 7553852 23602568 16979657 9636170 26496610 25852190
CDK2 SKP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 7553852 20160477 23602568 25271736 18239684 28446188 23226679 10386600 19270695 26496610 16189514 25852190 26186194 25788262 9858587 22770219 15355997 10559858 23807222 22311674 16979657 9636170 19686743 19270694 18604603 23455922
STAT3 CDK5 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 10347215 12223527 12947387 14607900 14670306 15218058 15356132 15573129 16418395 16697054 18776941 19380816 19473888 19595721 19596235 19596236 19686080 19772495 19847258 20093776 20237412 20406969 20581311 21840487 21922195 23124025 23454751 23589330 23850759 23953057 24857661 27216177 28186502 7543512
STAT3 CDK5 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 10347215 12223527 12947387 14607900 14670306 15218058 15356132 15573129 16418395 16697054 18776941 19380816 19473888 19595721 19596235 19596236 19686080 19772495 19847258 20093776 20237412 20406969 20581311 21840487 21922195 23124025 23454751 23589330 23850759 23953057 24857661 27216177 28186502 7543512
CDK5 PARP1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 12556884 16332722 16858402 17303408 19151707 20724832 21727086 21922195 23589330 23850759
CDK5 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25038288 16651438 19156541 12763138 28114390 16879821 23941877 15096606 26198700
HDAC1 MDM2 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
HDAC1 MDM2 â—¼   DOWN_REGULATES ✅ - 51.0 1.0 ACSN 10721693 11283614 11715018 11779693 11923280 12545156 12668723 14761977 15024084 15140942 15151915 15155580 15169778 15465827 15574337 15876864 16232121 17055429 17110379 17158541 17508028 17550342 17823410 19448627 19459846 20027199 20066118 20182602 20457558 20506250 20679392 20713526 20818389 21234400 21336307 21340684 21483453 21518799 21733352 21764762 2191300 21919891 22102694 22370643 22754780 22796940 23140366 23869868 6396087 9450543 9618481
MDM2 MDM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 69.0 1.0 Omnipath 17145710 10218570 17616658 16511560 22266850 12874296 21925390 25825738 21988832 25512388 16227609 22493164 22902369 25659040 18219319 12963717 15604276 18566590 12370303 19838211 26359458 27617579 25809483 34551723 10608892 23028042 22120712 25703327 12860999 32300648 16055726 24813712 17301054 12483531 23671280 17159902 27621617 25105592 20484049 20724842 27215386 10827196 26001071 11606419 23946421 19683495 20705607 24755078 25384516 20473904 12393902
SKP1 SKP2 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11516665 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15668399 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
SKP1 SKP2 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11516665 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15668399 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368