Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ETV3 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12007404 17525531
MAPK1 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17205132
CDK1 RFC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12930972
E2F4 HMGB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
MAPK1 ERF â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7588608 14729966
AR MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14619959 20610535
FGF2 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9490736 12750158
MAPK1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15263086 15466214
MAPK1 GABPA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19114066
ERF MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17699159 17525531
CREB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20864035
MYB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082531
STAT3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22943793 15810077
AR FGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11690559 20610535
ETV3 NFKB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18025162
CREB1 ETV3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14754893
MYB AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12096342 18945670
AR NR2C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17655826 20610535
AR KRAS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8423674 24172884
ETV3 DUSP6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22028473
ETV3 DDX20 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 22028472
NR2C1 NR2C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12615366 17645519
MYB NFIB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20647765 19841262
GLYR1 NSD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
NSD3 ETV3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 23455924 8417751
DDX24 GTPBP4 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
MYC CDK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC SMC1A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC RFC1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC SMC3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17353931 29467282
MYC CHD7 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 35140242 29467282
MYC NOC3L â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC XPOT â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC DDX10 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
RBM34 RBM28 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
RBM34 REXO4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
EHMT2 ZNF644 â—¼   PHYSICAL_INTERACTION 819.0 0.82 STRING 36370105
PROZ ETV3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PCDBB ERF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PCDBB ETV3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CASA1 ETV3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CASA1 ERF â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KRAS MAPK1 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
L3MBTL2 MGA â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
DDX24 KRR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 26344197 24981860
OLFM4 ERF â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
OLFM4 ETV3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
MRPL11 MRPS23 â—¼   PHYSICAL_INTERACTION 832.0 0.83 STRING 36370105
NSD3 MYC â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31638140 28628118 28205554
DDX24 DDX27 â—¼   PHYSICAL_INTERACTION 839.0 0.84 STRING 36370105
RNF113A SRRM2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
BLM MYC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 23750012 30415952 29467282
CREM CREB1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 7809053 16189514 22531917 25609649
DDX27 RBM34 â—¼   PHYSICAL_INTERACTION 858.0 0.85 STRING 36370105
SMC1A RFC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16438930 26344197
KRI1 KRR1 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
MYC DDX52 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17314511 30415952 29467282
MYC DDX20 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17353931 17314511 29467282
MYC LAS1L â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17353931 30415952 29467282
NFIB NFIA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 35140242 33961781 26871637
KRR1 DDX27 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 26344197
RBM34 NOC3L â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781
NR2C1 NR2C2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 30463901 12093744 21670149 9737983
RBM34 DDX31 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781
RFC1 SMC1A â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
MAPK1 STAT3 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
EHMT1 EHMT2 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
EHMT2 EHMT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21430779 26028330 27705803 21258344 24981860 34588438 28698370
CDK1 ATAD5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 31875566
MAPK1 DUSP6 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 Reactome 17208316 22569528 20463170
MAPK1 ETV3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 22028470
MYC DDX24 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21150319 17353931 30415952 29467282
E2F4 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11564866 12150994 18319725
NFKB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2191300 18490439 19219071
RAD21 SMC3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 15855230 17112726 21111234 17349791 26496610 10931856 21043528 17113138 18235444 22885700 22939629 31010829 21880767 22145905 33961781 24981860 15737063 16802858 20818333 26344197
RAD21 SMC1A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 19308699 17112726 31807710 26496610 10931856 21043528 17113138 11590136 22885700 22939629 31010829 22145905 23242214 33961781 24981860 15737063 20818333 26344197
AR SMC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22695118 23417242 16637073
NFKB1 STAT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12057007 25241761 16713569
MAPK1 DUSP6 â—¼   PHOSPHORYLATION ✅ - 0.9 0.9 Signor 15632084
DUSP6 MAPK1 â—¼   DEPHOSPHORYLATION ✅ - 0.9 0.9 Signor 12840032
GTPBP4 NOC3L â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
KRR1 PDCD11 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
KRR1 NOP14 â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
NOP14 PDCD11 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
DDX27 RBM34 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 33961781 26344197
DUSP6 MAPK1 â—¼   PHYSICAL_INTERACTION 944.0 0.94 STRING 36370105
ARID2 PBRM1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
SMC3 SMC1A â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17112726 21111234 31807710 17349791 26496610 10931856 17113138 18832153 11590136 12759374 30021884 22885700 22939629 9789013 31010829 21880767 11877376 23242214 24981860 27173435 11076961 26344197
GNL2 GTPBP4 â—¼   PHYSICAL_INTERACTION 989.0 0.99 STRING 36370105
RAD21 SMC3 â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
RAD21 SMC1A â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
MYC CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18802399 2237430 8065306 11085504
E2F4 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 15510213 17671431 11799067 11032828 17121828 17531812
E2F4 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15510213 16135806
CDK1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 26573794 12569365 22275373 25704883 17043241 23321516 9725910 24480624 21799006 24424504 28062857 21820033 25950519 28415597 27450452 25691442 21782001
MYC MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 22789855 21933022 16596619 23617883 8013639 20144848
DUSP6 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12840032 23331499 8626780 18060821 8910287 8670865 9596579 14690430 15632084 9922370 17322878
MAPK1 ERF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 28.0 1.0 Omnipath 10330152 14729966 22028470 18669648 19664994 19690332 7588608 16964243 18212344
MAPK1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 59.0 1.0 Omnipath 18448488 19413330 11335711 9343414 15465816 25584415 12576423 11350938 20068231 12681450 12763138 9872331 11780390 18491316 18669648 11404481 10521505 18691976 20058876 15979846 14551213 10446219
MAPK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10551811 17081983 8386367 17251036 91332050 17570479 1748630 7957875 27167001 15212693 1651323 15210690
MAPK1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18511414 9725910 10318905
STAT3 MYC â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
NFKB1 MYC â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 18490439 19219071 21725609 2191300 23178297 23572150
NFKB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 12504005 19469019 21790895 19766095 17018379 8289784 18566231 1515224
E2F4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 24573694 17132729 17699159 11689553 12757710
MYB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18408764 19609274 8382794 1679531 1588953 1594249 9596659 11259163 8474446 2233716 16088151
STAT3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19289167 17204573 18184402 22317895 20067773 15184887 15469392 10464281 9325164 20654581 21573184 17959148 22349830 9874564 20581311 19259613
SMC1A SMC3 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
STAT3 FGF2 â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
NFKB1 AR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 14576180 15517885 20159994 12165860 16619263
CREM CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22531917 16189514 7809053 1847666
NR2C1 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 16713569 12949936
NR2C2 AR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23331499 10611280 16713569