MAPK12
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HSPA5
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
HSPA8
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
DUSP6
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TRIM9
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
MAPK1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TMED10
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ATXN1
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
CCT6A
|
APP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
APP
|
HSPB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
TRIM9
|
ATXN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ATXN1
|
CCT6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
FXR1
|
CAPRIN1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
G3BP1
|
CAPRIN1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
24981860
|
G3BP1
|
CAPRIN1
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
6665011
18005740
|
CAPRIN1
|
G3BP1
|
â—¼ COLOCALIZATION
|
✅
|
|
0.8
|
0.8
|
mint
|
18005740
6665011
|
CCT8
|
CCT6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
000924
30021884
|
TEX11
|
DUSP6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
MDFI
|
DUSP6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
PHB2
|
DUSP6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
ETS1
|
DUSP6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20097731
|
ETS2
|
DUSP6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18321244
18848526
|
ETV3
|
DUSP6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
22028473
|
FOXO3
|
DUSP6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17452451
|
ZBTB16
|
DUSP6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19723763
|
DUSP6
|
MAPK6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18632752
|
ETS2
|
ETS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9334186
16189514
|
FOXO1
|
INS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
22968147
21335550
|
FXR1
|
MAPK7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
FXR1
|
ZNF212
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
3002166
21653829
|
MAPK1
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15778365
|
MAPK11
|
MAPK14
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23602568
21900206
|
CCT2
|
CCT4
|
â—¼ CORRELATES
|
|
+
|
0.8
|
0.8
|
CCLE
|
31978347
|
MAPK8
|
MAPK9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
805.0
|
0.8
|
STRING
|
36370105
|
CCT4
|
CCT6A
|
â—¼ CORRELATES
|
|
+
|
0.81
|
0.81
|
CCLE
|
31978347
|
G3BP1
|
FXR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
26777405
29395067
|
G3BP1
|
HSPA9
|
â—¼ PHYSICAL_INTERACTION
|
|
|
820.0
|
0.82
|
STRING
|
36370105
|
MAPK3
|
HSPB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
21575178
8774846
25241761
|
ETS2
|
ETS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
16189514
9334186
|
MAPK3
|
DUSP6
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.86
|
0.86
|
Signor
|
15632084
|
DUSP6
|
MAPK3
|
â—¼ DEPHOSPHORYLATION
|
✅
|
-
|
0.86
|
0.86
|
Signor
|
12840032
|
G3BP2
|
G3BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
33961781
26777405
24981860
29395067
26186194
28514442
|
G3BP1
|
G3BP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
CCT2
|
CCT8
|
â—¼ CORRELATES
|
|
+
|
0.87
|
0.87
|
CCLE
|
31978347
|
MAPK1
|
MAPK14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
ETS1
|
FOXO1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
CAPRIN1
|
G3BP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
MAPK1
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
887.0
|
0.88
|
STRING
|
36370105
|
CCT6A
|
CCT8
|
â—¼ CORRELATES
|
|
+
|
0.89
|
0.89
|
CCLE
|
31978347
|
MAPK3
|
DUSP6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
211739200
12840032
8214413
|
MAPK3
|
DUSP6
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
17208316
22569528
20463170
|
MAPK1
|
DUSP6
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
17208316
22569528
20463170
|
WT1
|
ETS1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20842112
18212735
|
ETS1
|
MYB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
7848925
8999884
|
MAPK1
|
ETV3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
22028470
|
MAPK6
|
FOXO3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
MAPK3
|
FOXO3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
19282669
|
HSPA8
|
MAPK8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
INS
|
MAPK6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
MAPK11
|
MAPK14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
WT1
|
MYB
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
7559553
|
MAPK1
|
DUSP6
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.9
|
0.9
|
Signor
|
15632084
|
DUSP6
|
MAPK1
|
â—¼ DEPHOSPHORYLATION
|
✅
|
-
|
0.9
|
0.9
|
Signor
|
12840032
|
CCT2
|
CCT6A
|
â—¼ CORRELATES
|
|
+
|
0.9
|
0.9
|
CCLE
|
31978347
|
CCT4
|
CCT8
|
â—¼ CORRELATES
|
|
+
|
0.9
|
0.9
|
CCLE
|
31978347
|
DUSP6
|
MAPK3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
RPS27
|
SERBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
943.0
|
0.94
|
STRING
|
36370105
|
DUSP6
|
MAPK1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
944.0
|
0.94
|
STRING
|
36370105
|
RPL39
|
RPS27
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
RPL39
|
SERBP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
CCT2
|
CCT6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CCT4
|
CCT6A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CCT6A
|
CCT8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
994.0
|
0.99
|
STRING
|
36370105
|
CCT4
|
CCT8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
CCT2
|
CCT8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
997.0
|
0.99
|
STRING
|
36370105
|
CCT2
|
CCT4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
MAPK10
|
APP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
8131745
14970211
22958823
11877420
24610780
15936948
|
MAPK8
|
APP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12917434
14970211
24610780
20122754
15936948
|
CAPRIN1
|
G3BP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
17210633
34799561
18005740
|
MAPK9
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
19623618
18423204
25639486
22074626
19667122
18604449
|
CTNNB1
|
FOXO3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23331499
15905404
21071413
17254970
|
CTNNB1
|
FOXO1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
23331499
17254970
15905404
|
DUSP6
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
12840032
23331499
8626780
18060821
8910287
8670865
9596579
14690430
15632084
9922370
17322878
|
DUSP6
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
14.0
|
1.0
|
Omnipath
|
12840032
23331499
8626780
8910287
9535927
9596579
14690430
9922370
18988627
17322878
|
ETS1
|
MAPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
8552081
10358095
20534573
11782450
15572696
|
ETS1
|
MAPK3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
8552081
10358095
20534573
11782450
15572696
|
MAPK7
|
ETS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
8761310
12048211
20361728
25885538
8552081
11948414
|
MAPK1
|
ETS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
21494553
21449613
25241761
16045329
23991633
20361728
11570862
22521293
11948414
|
MAPK3
|
ETS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
8761310
23331499
12048211
11948414
|
ETS2
|
MAPK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
8552081
10358095
20534573
11782450
15572696
|
ETS2
|
MAPK3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
Reactome
|
8552081
10358095
20534573
11782450
15572696
|
FOXO3
|
FOXO1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19244250
16100571
18202312
23509296
19690465
|
FOXO3
|
INS
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16840535
22563476
19608644
12027802
|
MAPK1
|
FOXO3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
18204439
29445193
22128155
10102273
|
MAPK14
|
FOXO3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22128155
23857333
|
MAPK13
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12738796
18039929
11274345
15187187
|
MAPK14
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
15187187
21675959
18039929
12738796
11157753
22521293
17255949
11238443
11274345
12697810
|
MAPK1
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12975377
23602568
16424009
19058874
23397142
21707490
|
MAPK11
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12738796
18039929
11274345
15187187
|
MAPK13
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
12738796
18039929
11274345
15187187
|
MAPK14
|
MAPK3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
15187187
21675959
18039929
12738796
23397142
11238443
11274345
12697810
|
MAPK3
|
MYB
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
8798443
8960373
|
MYB
|
MAT2A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
11115410
11427482
21406062
|