Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
H2BC21 H2AZ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 H2AZ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
A2M H2AZ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
H2BC9 H2AZ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC12L H2AZ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC5 H2AZ1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2AZ1 ABCF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2AZ1 DNAH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2AZ1 Q8N2B8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2AZ1 MYH15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2AZ1 FAU â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2AZ1 AFF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2AZ1 ACTR6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20473270 7986133
H2AZ1 USF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2AZ1 SLCO6A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SP1 H2AZ1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7880446
PARP1 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1429884
KAT5 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10096020
USP22 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18469533
USP3 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19342239
PRMT5 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18992153
USP16 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19615732
MYSM1 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17707232
RPS6KA5 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15010469
EP300 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19056256
HDAC2 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
BRCC3 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19202061
RING1 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15386022
H2BC12L H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC12L DNAH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC12L H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC21 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC9 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC5 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H4C6 H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1003064107 20498094
H3-4 ABCF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 TOP2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
LMNA H2BC21 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC1 H2BC21 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC21 SSRP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC21 YEATS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC21 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC9 VPS72 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC9 AFF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC9 PARP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC9 ABCF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC9 TOP2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC9 DNAH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC9 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
A2M H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
H3C2 XRCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080577 0913709107
H3C2 PRKDC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080577 0913709107
H3C2 PARP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080577 0913709107
H3C2 XRCC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080577 0913709107
PARP1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1429884
HDAC2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
KAT5 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10096020
MYC H2BC8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12747840
PRMT5 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1209814109 23071334
H2BC5 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H4C6 KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SP1 H4C6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7779811
H4C6 PRMT5 â—¼   METHYLATION ✅ 2.0 0.8 intact 1209814109 23071334
PARP1 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1429884
HDAC2 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18675384
A2M KAT5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
EPC1 BRD8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
BRD8 MRGBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
BRD8 ING3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
BRD8 DMAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
BRD8 TRRAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
EPC1 BRD8 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
BRD8 MRGBP â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
BRD8 DMAP1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
BRD8 ING3 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
BRD8 TRRAP â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
MRGBP DMAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
EPC1 DMAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
DMAP1 ING3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
DMAP1 TRRAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
MRGBP DMAP1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
EPC1 DMAP1 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
DMAP1 TRRAP â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
DMAP1 ING3 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
DZIP3 SSRP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18206970
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16204234
RUVBL2 EP400 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218484 16601686
EPC1 ING3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
EPC1 MRGBP â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
EPC1 TRRAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
EPC1 ING3 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
EPC1 MRGBP â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
EPC1 TRRAP â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
ESR1 HMGB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17922863 18414489
ESR1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18414489
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
MYC HDAC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20697349
MRGBP ING3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
ING3 TRRAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
MRGBP ING3 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
ING3 TRRAP â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
KAT5 LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
MRGBP TRRAP â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17320397 19164757
MRGBP TRRAP â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17320397 19164757
MYC MSH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12808131 11983916
MYB MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15082531
PARP1 RAD23B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
SP1 PRKCB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12105191 20179320
PRKDC RNF8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SP1 SMARCA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18243132
CTCF PARP1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 14759373 20038529 19450526
MORF4L1 VPS72 â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
MORF4L1 RUVBL1 â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
ACTL6A MRGBP â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
ESR1 ABCF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
MYC CDK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MBTD1 DMAP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 27153538
MBTD1 EP400 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27153538 29028833
ING3 EP400 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26496610 29028833
EPC1 EP400 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27153538 29028833
ESR1 EP400 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 21182205
MBTD1 EPC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 27153538
VPS72 EPC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 15647280
TRRAP EPC2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
VPS72 ING3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15647280 26496610
MBTD1 TRRAP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27153538 31281901
MYC MRGBP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 35140242
XRCC6 MSH2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22863883 21075794
MYC PRKDC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC SRCAP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 35140242 29467282
MYC SSRP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC RING1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC TOP2A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC XRCC5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
VPS72 SRCAP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15647280 22939629
SSRP1 XPC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
XRCC6 XPC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RUVBL2 YEATS4 â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
VPS72 BRD8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 15647280 31753913
MYC BRD8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 35140242 20946988 31753913
KAT5 BRD8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 14966270 27153538 20946988 26186194 31753913 28514442
MBTD1 BRD8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 27153538 31753913
DMAP1 MYC â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30415952 20946988 35140242
MRGBP EP400 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 15647280 12963728 28514442 29028833
VPS72 EPC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27153538 15647280 29028833
TRRAP EPC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27153538 26496610 29028833
KAT5 EPC2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 27153538 20946988 26186194 28514442
MYC EPC2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30415952 20946988 35140242
MYC LMNA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21150319 17314511 29467282
MRGBP MBTD1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 27153538 17573780
XPC RAD23B â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 34591642
KAT5 MYC â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
WEE1 CDK1 â—¼   PHOSPHORYLATION ✅ - 0.83 0.83 Signor 16096060
CDK1 WEE1 â—¼   PHOSPHORYLATION ✅ - 0.83 0.83 Signor 15070733
MYC SP1 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
DMAP1 ZNHIT1 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
ACTR6 VPS72 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
EP300 XRCC6 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21988832 15023334 33742100
LMNA PARP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 29568061 25948554 30419336 22412018
PRKDC PARP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20085707 16794079 21575865 9398855
BRD8 RUVBL2 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
CDKN1A EP300 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
TRRAP BRD8 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 12963728 26496610 31753913
EP300 PRKDC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33742100 30110629 20808282
EP400 MORF4L2 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
ESR1 MYLK2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21182203 25604459 21182205 31527615
PARP1 HDAC2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 34079125 16204234 20596014
SUPT16H SSRP1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 5218941 16902406
MORF4L2 MRGBP â—¼   PHYSICAL_INTERACTION 0.85 0.85 HuRI 32296183
TRRAP VPS72 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
EP400 VPS72 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
SSRP1 PARP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28514442 34079125
PARP1 TOP2A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20085707 34079125
XRCC6 SSRP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28514442 30585729
XRCC5 TOP2A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20085707 12393188
DMAP1 EP400 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
EPC1 RUVBL2 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
EPC2 MORF4L2 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
VPS72 DMAP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 26344197 15647280 22939629 20946988 29028833
MYC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12776737 16287840 32140074 15616592 16126174 17157259
MYC EPC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21150319 30415952 20946988 35140242
KAT5 EPC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 32296183 14966270 27153538 20946988 26186194 28514442 29028833
MRGBP EPC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 16230350 15647280 12963728 27153538 17573780 28514442
ING3 EPC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 16387653 26496610
MRGBP EPC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 16230350 15647280 17573780 28514442
MYC HDAC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22286234 17314511 30415952 20195357
MYC IPO9 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17314511 29467282 17353931
MRGBP KAT5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 16230350 15647280 18218781 12963728 27153538 26186194 17573780 28514442
MYC SMC2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17314511 29467282 17353931
XPC PARP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 34079125 28760956
XRCC6 XRCC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 30585729
MBTD1 MORF4L1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MORF4L1 MORF4L2 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
AFF4 EAF2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
EP300 NAP1L1 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
NAP1L1 NAP1L4 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
MBTD1 YEATS4 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
KAT5 MBTD1 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
KAT5 VPS72 â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
CDK7 ESR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10949034 31527615 15461668
SP1 EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10651903 34252870 16478997 11030335 11517158 15647279 17623675 17906698 28425985 32115405 31536933 12200149 24530506 23714681 10362258 22415975 16734381 19062177 10899165
PARP1 HMGB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28190768 29721183 34079125
VPS72 KAT5 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 15647280 27153538 20946988 26186194 28514442 29028833
PARP1 XRCC5 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EPC2 TRRAP â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
BRD8 MORF4L2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
RING1 RNF2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
ACTR6 DMAP1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
BRD8 MORF4L1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
YEATS4 ZNHIT1 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
MRGBP RUVBL2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
MYC TRRAP â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
BRD8 KAT5 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
H3C2 H4C6 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 7219095 19498464
MRGBP BRD8 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20051959 33961781 24981860 16230350 15647280 12963728 31753913 17573780 28514442
ING3 BRD8 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16387653 26496610 31753913
ING3 DMAP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 14966270 26496610 16387653 20946988
ING3 EPC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16387653 27153538 26496610 14966270
TRRAP ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11931763 16260778 12837248 12738788 31527615
HDAC2 SP1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
ING3 YEATS4 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
MYC XRCC6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30415952 17314511 29467282
MORF4L1 RUVBL2 â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
ACTL6A MORF4L1 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
BRD8 YEATS4 â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
ING3 RUVBL1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
MRGBP RUVBL1 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
MRGBP YEATS4 â—¼   PHYSICAL_INTERACTION 894.0 0.89 STRING 36370105
ING3 MRGBP â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
ING3 MORF4L1 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
SRCAP YEATS4 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
ESR1 H2AZ1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19515975 23108396 20023423
DZIP3 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18206970
PIM2 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20307683
A2M CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRKCB BRAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1386920 17570479 12917261
MSH2 CDKN1A â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SSRP1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15557281 16410722 12374749
KAT5 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17671089 20351180 16601686
MYC EP400 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 35140242 18413597 21150319 29467282 30415952 20946988 17314511 11509179
EP400 KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20351180 14966270
PRKDC FH â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 29991493 26237645
LMNA PRKCB â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 22986494 8463284 8034666
MYC LMNA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC MSH2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 29467282 30415952 28205554 17314511 28628118 12584560
SP1 MYB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7559553
TRRAP MYC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 35140242 12077335 17353931 21150319 32140074 16705173 9708738 29467282 11839798 30415952 20946988 17314511 11511539 19818711 12660246 10611234
MYC SLBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC PRKDC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
MYC NAP1L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12747840
MYC SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11274368 16713569
XRCC1 PARP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24778456 18971944 12897160 15555565 30260704 34079125 14500814 16713569 9584196 20302655 34111398 15044383 20303835
XRCC5 PRKDC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 26496610 22404984 15520013 21679440 26446488 26344197 17308091 15941674 28154079 16857680 20711232 19303849 20023628 15758953 20085707 10750018 10446239 33005030 9312071 28345663 12393188
XRCC6 PRKDC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8422676 20711232 19303849 26175416 28345663 30585729 17308091 22939629 26496610 10750018 15941674 33005030 21969602 15520013 10064605 21575865 26446488
XRCC6 XRCC5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 22939629 15367688 26496610 26774286 21172662 11196700 15520013 22863883 21679440 17159921 30021884 14681455 26446488 26344197 10207052 30585729 17308091 11493912 10757784 10219089 10984620 19118032 12145306 32296183 28035050 19177010 18809223 21454661 15910003 10783163 28514442 21070772 25574025 15023334 7699019 10750018 10446239 22451927 33005030 9488450 17283121 19906305
EP300 MYB â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
ESR1 SP1 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
KAT5 RUVBL2 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
VPS72 YEATS4 â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
PARP1 XRCC6 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
CDK1 CDKN1A â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
KAT5 MRGBP â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
MRGBP VPS72 â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
SRCAP ZNHIT1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
EPC1 MORF4L2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
KAT5 MORF4L2 â—¼   PHYSICAL_INTERACTION 913.0 0.91 STRING 36370105
DMAP1 MORF4L1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
EP300 SP1 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
ING3 KAT5 â—¼   PHYSICAL_INTERACTION 917.0 0.91 STRING 36370105
SSRP1 SUPT16H â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
DMAP1 KAT5 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
RUVBL2 VPS72 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
ACTL6A KAT5 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
FAU RIOK2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
RUVBL1 YEATS4 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
XRCC5 XRCC6 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
SRCAP VPS72 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
HDAC2 MORF4L1 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
MORF4L1 YEATS4 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
VPS72 ZNHIT1 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
ACTL6A RUVBL2 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
EP400 MORF4L1 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
KAT5 RUVBL1 â—¼   PHYSICAL_INTERACTION 936.0 0.93 STRING 36370105
EPC2 KAT5 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
KAT5 YEATS4 â—¼   PHYSICAL_INTERACTION 937.0 0.93 STRING 36370105
ACTL6A EP400 â—¼   PHYSICAL_INTERACTION 938.0 0.93 STRING 36370105
XRCC6 PRKDC â—¼   RELOCALIZATION ✅ + 0.93 0.93 Signor 19133841
KAT5 MORF4L1 â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
MORF4L1 TRRAP â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
EPC1 KAT5 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
TRRAP YEATS4 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
TRRAP USP22 â—¼   PHYSICAL_INTERACTION 943.0 0.94 STRING 36370105
ACTL6A RUVBL1 â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
EP400 TRRAP â—¼   PHYSICAL_INTERACTION 947.0 0.94 STRING 36370105
EPC2 MRGBP â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
EP400 KAT5 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
RUVBL2 ZNHIT1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
EP400 YEATS4 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
EP400 MRGBP â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
RUVBL2 TRRAP â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
DMAP1 EPC1 â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
KAT5 TRRAP â—¼   PHYSICAL_INTERACTION 953.0 0.95 STRING 36370105
ACTL6A DMAP1 â—¼   PHYSICAL_INTERACTION 954.0 0.95 STRING 36370105
MORF4L1 MRGBP â—¼   PHYSICAL_INTERACTION 956.0 0.95 STRING 36370105
EPC1 MORF4L1 â—¼   PHYSICAL_INTERACTION 958.0 0.95 STRING 36370105
EPC1 YEATS4 â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
EPC2 MORF4L1 â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
XRCC5 XRCC6 â—¼   PHOSPHORYLATION ✅ 0.96 0.96 mint 10783163 5212534
DMAP1 RUVBL2 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
EPC2 YEATS4 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
EP400 RUVBL2 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
EP400 RUVBL1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
DMAP1 SRCAP â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
DMAP1 VPS72 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
ACTL6A TRRAP â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
RUVBL1 ZNHIT1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
DMAP1 MRGBP â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
RUVBL1 VPS72 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
DMAP1 RUVBL1 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
RAD23B XPC â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
PRKDC XRCC6 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PRKDC XRCC5 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
ACTR6 ZNHIT1 â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
ACTR6 RUVBL1 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
DMAP1 YEATS4 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RUVBL1 TRRAP â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
ACTR6 RUVBL2 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
ACTR6 SRCAP â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
RUVBL1 SRCAP â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
RUVBL2 SRCAP â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
RUVBL1 RUVBL2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
SSRP1 SUPT16H â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
XRCC5 XRCC6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MYC H2AZ1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18414489 22055461 12695333 11085504
RNF8 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18001824 19797077
RNF2 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17636032 15386022
XRCC6 H3-4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC5 H3-4 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
H3-4 KAT5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 11934988 15279782 12792649 11893489 10959836
PRMT5 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22231400 20084102 15670829
EP300 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21875947 19270680 19158375 20587414
RPS6KA5 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 20129940 10464286 15994958 14625384 10469656
XRCC5 H4C6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 H4C6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
MYC H4C6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12747840 12695333
PRMT5 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 19234465 29227283 15670829 20951943 23071334
KAT5 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12776177 10096020 32814053 24525235 16844118
EP300 H4C6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19423655 11689053 16332960
CDK7 CDK1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 11900249 12648680 15703371 16697054 17386261 17884153 19667075 19809470 19847258 7533895
LMNA CDK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 22986494 2188731 2344612 2188730
CDK1 WEE1 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17596790 17660363 18414028 18543256 18590585 18995830 19652693 19686080 23508805 23897299 7575488 9892021
TP63 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11593387 19861536
MYC CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18802399 2237430 8065306 11085504
WEE1 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 135.0 1.0 Omnipath 26658951 28126323 15592455 11202906 27196765 20406171 19415658 8578591 22709126 26006103 11730318 20813250 96108162 26025928 11807090 26057002 23410205 24666614 19651622 16096060 15350223 23166842 24716182 8428596 22770610 25174607 28396830 20498628 20530684 25361894 20465818 11527575 25733813 18285803 25283841 25458954 1384126 16497976 17480229 9552418 10564259 24143279 22546375 18669648 7749193 22494620 29930204 18691976 21660227 17192257 9001210 29044141 20347419 23727417 15837193 17016520 19901323 26804466 28928160 21389100 14972559 24415942 24651440 7743995 20068231 25344910 27878946 10209262 27669826 8972180 10896159 28539822 19821025 26131711 25774168 24136233 24536047 23537585 8084605 7774574 24927813 26899266 19305423 25609063 19413330 18385244 25301733 16083285 27196784 18452278 26081366 28264028 29217775 29500418 22836368 11751453 18378775 17718912 20609246 20058876 9268380 27532275 18469858 23494566 24630986 15964826 24970150 12186947
CDK7 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 85.0 1.0 Omnipath 16565220 18767875 11113184 33657372 27303922 19690332 19667075 15703371 10913154 14988404 1532335 29793495 20360007 7799941 19158392 19664995 33574676 19809470 8548828 7533895 17386261 34489572 26881937 17554681 20068231 18452278 21900495 18669648 12814430 16327805 18691976 15868411 8441405 21778139 25849598 27908669 12459251 1833185 19651622 22263797 19847258 19707596 17924679 20347419 29435156 18220336 34370741 19369195 22505032 21468563 17884153 12663041 22425727 7944411 12648680 11900249 8344251 16697054 31429764 24970150
CDKN1A CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 9467962 26186194 21308745 15340381 23602568 23543736 24218572 17679094 15077146 26496610 12973835
CDK1 SLBP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18490441 23286197 12588979 27773672
CDK1 LMNA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 80.0 1.0 Omnipath 19007248 16565220 20166139 17081983 18767875 20393185 23870088 17137347 19413330 18187866 19194518 30190500 19664995 19415658 15302935 7925482 16083285 95010153 24741066 20068231 18452278 18077418 17570479 18491316 18669648 32071079 23427156 2344612 18691976 26922519 17287340 18815303 20068230 19651622 20058876 19691289 17924679 22367880 19165338 19664994 18707149 21389115 16964243 18212344 24556839
CDK1 USP16 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10077596 16189514 28380042 24013421
CDK1 KAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 21658600 12468530 16103124 17570479 26829474 18669648
CDK1 NPM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 49.0 1.0 Omnipath 17081983 12058066 27253419 22285574 25908633 20333249 16912078 27553022 19933706 16083285 20068231 27619510 17570479 18669648 7213797 81161106 26536659 11278991 17287340 17924679 15190079 14670079
CDK1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 25398907 28831131 20150555 22266860
CDKN1A CDK7 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 Reactome 8139570 20107323 16782892 23622515 23737759 19487459 19075005 7954814 19458076
CDK7 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 30257348 10949034 15461668 9528769 22879364 12118371 28423697 27748765 15059947 16076840 7491495 12093745 23850489 15528270 7838153
TP63 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 15790310 10383130 21480565 12640112 20123734 17404570 16007146 16410722 15965232 12374749 17965458 21093383 23665236 9405685
ESR1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15557281 16628468 20696891 16847062 12151347 11517191 15378598 11274368 16469747 17681750 20301197 22787161 23349794
MYC CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 41.0 1.0 Omnipath 15190211 14519204 15616584 12408868 19174556 21949397 10319992 12553001 16204065 12545156 20878079 21042278 21400515 20190815 16706751 23804320 15757889 10920185 19270520 16452181 12408820 15528212 22371483 12565816 17885207 12384701 11274368 19150257 20551174 15899785 21120446 15071503 15474507 22814619 12835716 12748190 16738884 15711923 18636159
SP1 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 101.0 1.0 Omnipath 9580699 15978937 15557281 11064455 16103879 19584258 20301197 20935676 15961274 15361832 11274368 11842244 15489892 15302882 10212208 12796485 23184467 14529564 12806965 9819384 10321829 10649433 12434298 18270969 18850004 16081043 9183012 21858218 10809237 9618481 16298343 11574165 10362258 11384995 15659839 14744793 10030670 17090534 10733944 19318349 12665570 18202149 17516505 15033443 22001409 17885207 10485470 9553133 15345676 15694838 22427654 17556661 10506225 23066038 15979845 18636159 14527674 24821727 15899840 14755691 12151347 24589735 18210215 23877711 11953011 21311948 15528212 15790310 10878024 22132221 12782287 12773551 8995437 21184768 12379120 17026958 24451377 10601254 8557703 16810128 16533812 7499379 10625687 15389873 16706751 12727210 21325288 16818630 18419600 15041706 23235480 19244234 15694666 23329847 18509005
EP300 CDKN1A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10362258 15509808 21858218 22000024 21245169
EP400 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 17671089 20548951
MYC CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 15528212 9618481 12545156 17550342 10454538 15155580 11283613 10920185 11283614
SP1 CDKN1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17026958 9389648 9618481 17550342 12545156 11013220 15155580 11074002
CTCF MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10625678 8649389 2284094 12032779 19568426 24725430 12524457 8246978 12897849 9591631 1795697
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15965232
EP300 MYB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19608861 29954426 18585056 15691758 10656693 25740244
SP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12237165 19351845 11345900 21235772 23209644 12429135 18006846 10982795 22622808 15691879 21191649
SSRP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15171726 23810005 1406642 19946334
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
XRCC5 KAT5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XRCC6 KAT5 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
KAT5 PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16603769 16904321
KAT5 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12776177 19150978 15572685 34650217
MYB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18408764 19609274 8382794 1679531 1588953 1594249 9596659 11259163 8474446 2233716 16088151
SP1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11470523 9492315 2284094 8437848 7753559 8355712 2057364
MYC NPM1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15589822 16857742 14519204 23271972 11983916 11085504
MYC PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23277454 12695333
MYC TRRAP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17848523 23775087 11511535 20194507
TRRAP MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 17145710 17353931 11511539 12660246 20194507 9708738
PLK2 NPM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15190079 20352051
PARP1 XRCC1 â—¼   PHYSICAL_INTERACTION 70.0 1.0 ACSN 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 XRCC1 â—¼   SHARES_COMPLEX 70.0 1.0 ACSN 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
SP1 PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9428683 9493965 17003407 17961220 11278663 12657578 15777284
PARP1 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9592149 18971944 15555565 19643912 15044383 14500814 16713569 24778456 12897160 20303835 20302655 9584196
PARP1 SUPT16H â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18406329 16682447
PRKCB TOP2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 19007248 12569090 19691289 17081983 8939955 96081879 18691976 9804834 7499337 11940573 15212693
PRKDC USF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20817607 26490400 23219531 19303849
RNF8 XRCC6 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
XPC XPC â—¼   KO_DOWN_REGULATES ✅ - -3.23 3.22 PKG 28854368
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368
MSH2 MSH2 â—¼   KO_DOWN_REGULATES ✅ - -6.48 6.47 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368