Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ZRANB1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19373254 7288828
UBC ZRANB1 â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
USP3 H2AZ1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19342239
H3C2 SNAI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7903691 20389281
H3C2 SUZ12 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
TP53 H3C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16980608
AURKA USP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001737 24358021
AURKA TP53 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 14702041 19121998
CHEK1 TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5218401 16511572
DDX58 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16153868 19479062
EIF3I EIF3G â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219314 17094969
IFIH1 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16153868 19479062
TP53 PYCARD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16715133
TP53 PYCARD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
UBC SNAI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7718905 20385133
EIF3B EIF3H â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
EIF3G EIF3I â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
EIF3D EIF3H â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
EIF3A EIF3H â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
HIST1H2AB HIST1H2BB â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
TP53BP1 UBC â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
EIF3C EIF3H â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
EIF3G EIF3B â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 24396066
EIF3A EIF3C â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
AURKA TP53 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CHEK1 TP53 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
EIF3C EIF3D â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
TRAF6 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
EIF3H PRRC2B â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
EIF3A EIF3D â—¼   CORRELATES + 0.87 0.87 CCLE 31978347
DDX58 UBC â—¼   PHYSICAL_INTERACTION 892.0 0.89 STRING 36370105
TP53 CDC25A â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18281511 17001315 19060337
TP53 EIF3B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16980608
TRAF6 UBC â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
MDC1 TP53BP1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
EIF3H EIF3B â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 18628297 24981860 26344197 19615732 22939629 18599441 32269044 26186194 28514442
EIF3H EIF3D â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 22190034 24981860 26344197 19615732 22939629 32269044 26186194 28514442 22863883 23623729
UBC TP53 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 17568776 5220017
MDC1 USP3 â—¼   KO_DOWN_REGULATES ✅ - -0.97 0.96 PKG 28854368
CDC25A CHEK1 â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
CHEK1 TP53BP1 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
EIF3H EIF3C â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 24981860 26344197 19615732 22939629 18599441 32269044 26186194 28514442 22863883 23623729 30021884
UBC ZRANB1 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
TP53 TP53BP1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
EIF3B EIF3A â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 14519125 19245811 18628297 24981860 26344197 14688252 8995410 22939629 18599441 30573685 11169732 16541103 9822659 17469741
EIF3G EIF3A â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 14519125 33961781 24981860 26344197 22939629 18599441 24396066 26186194 28514442 9822659 9341143
EIF3B EIF3D â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EIF3B EIF3C â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EIF3C EIF3D â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EIF3C EIF3I â—¼   PHYSICAL_INTERACTION 994.0 0.99 STRING 36370105
EIF3A EIF3C â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EIF3C EIF3H â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EIF3C EIF3G â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EIF3D EIF3G â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EIF3D EIF3I â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF3G EIF3I â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF3H EIF3I â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
EIF3A EIF3D â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3A EIF3H â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3B EIF3H â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3B EIF3G â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3B EIF3I â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3D EIF3H â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
EIF3A EIF3I â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3A EIF3B â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3A EIF3G â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EIF3G EIF3H â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CHEK1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 18451105 20068082 23844048 12560483 18066052 20948546 21357687 18243098
AURKA H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 14583461 15108802 17938195 15249581 12234980 12588998 12082625
AURKA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 50.0 1.0 Omnipath 24173284 22864622 25217103 24089029 16713569 19413330 25848977 17999753 23565200 25333414 23201157 16552184 10884347 1956339 26186194 29455673 15469940 15749021 18974145 21502403 17287340 28043820 22396649 92065884 12198151 27933271 22852086 12064478 30266789 25398437 17259342 22350019 25634113 14702041
CHEK1 CDC25A â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 15459660 15798197 17102137 17116885 17296725 17384638 17568790 17582221 18677104 19793801 20126263
CHEK1 CDC25A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 75.0 1.0 Omnipath 12676583 22040655 29435105 12759351 14681206 18677104 20860841 15798197 19793801 22655267 12963847 16682204 14752276 16647857 15736430 29725502 17116885 17582221 20126263 16697662 18167338 19075565 9278511 18480045 17384638 21148633 21252624 27493659 12110582 17030123 23335075 20068082 11298456 27908669 27213455 25936524 15459660 28150240 20798862 22263797 27038604 17296725 14559997 12399544 17102137 17568790 16488126
TP53 CHEK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 21546904 11158294 20190799 19435816 18632613 15016801 19395378 11152453 18753293
CHEK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 20950777 18778462 25545885 18677104 20860841 15798197 19793801 22891162 16511572 23852422 16713569 15865930 11551930 19923893 15467443 11709713 21748595 17116885 15659650 17582221 26384650 10673501 17384638 23966620 23892398 17118344 9765199 15140942 19788416 10801407 18319725 12781359 12897801 25823026 15459660 23296650 15024084 17296725 17102137 11896572 17339337 19933256 20526329 28140789
EIF3I EIF3A â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 14519125 33961781 24981860 26344197 17353931 22939629 8995409 18599441 26186194 28514442
MDC1 TP53BP1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
MDC1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16009723 17145710 18087291 17925396 12607005
TP53BP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 40.0 1.0 Omnipath 25579814 12110597 25837623 16713569 14978302 22653443 26022179 27546791 8016121 12351827 15611139 15364958 14985081 19433796 17805299 25651062 11877378 17634560 22084066 20307547
MDC1 WDTC1 â—¼   KO_DOWN_REGULATES ✅ - -1.09 1.08 PKG 28854368
NHEJ1 USP3 â—¼   KO_DOWN_REGULATES ✅ - -1.75 1.74 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
NHEJ1 NHEJ1 â—¼   KO_DOWN_REGULATES ✅ - -6.47 6.46 PKG 28854368
TP53BP1 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -9.54 9.53 PKG 28854368