Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PARP1 CUL4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
E2F4 MKI67 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17531812
H3C2 PARP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080577 0913709107
PARP1 CUL4A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 23045548 23319653
PARP1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1429884
H3C2 PRKDC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080577 0913709107
E2F4 PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 16135806
H3C2 XRCC5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080577 0913709107
H3C2 XRCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20080577 0913709107
E2F4 H3C2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799066
E2F4 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18319725 14532106
H3C2 EZH2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H4 PARP1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 30804502 27248496 33961781 19470756 20525793
CBX1 CBX3 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
WDR76 CBX1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27248496 31353912
WDR76 CBX3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27248496 31353912
HELLS PARP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 31417184
WDR76 PRKDC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27248496 31353912
WDR76 RPA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27248496 31353912
WDR76 SSRP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 25817432
SSRP1 XPC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
IKZF1 WDR76 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CUL4A WDR76 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30655611 17041588
MYH9 WDR76 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31353912 26496610
IMDH1 WDR76 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SSA27 WDR76 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
WDR76 MAP1B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27248496 31353912
WDR76 H2A2A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27248496 31353912
WDR76 SSBP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27248496 31353912
WDR76 LMNA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27248496 31353912
WDR76 TCPE â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31353912 25817432
WDR76 DNJA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27248496 31353912
WDR76 SIR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 31353912
WDR76 DNLI3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 27248496
WDR76 TCPH â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31353912 25817432
XRCC6 XPC â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SSBP XRCC5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 32877691
SSBP XRCC6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 32877691
SSBP H4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22453275 27248496
DCAF8 TCPH â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DCAF8 TCPB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DCAF8 TCPG â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
H3C2 CBX1 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 16415788 5218238
CBX1 H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.83 0.83 mint 16415788 5218238
CBX1 H4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24981860 21888893 27248496
H31 WDR76 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31353912 25281560 27248496
KCC2D WDR76 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 27248496
WDR76 XRCC6 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27248496 31353912 25817432
WDR76 XRCC5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 27248496 31353912 25817432
WDR76 DNJA2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 27248496 31353912
WDR76 XPC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 27248496 31353912
XPC H4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 27248496 30804502
TCPE SSA27 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32296183 16189514 22939629 25416956
SSA27 TCPH â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32296183 25416956 11591653
H31 DNLI3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 33961781 25281560 29568061
H4 DNJA2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19862764 27248496 30804502
LMNA PARP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 30419336 22412018 25948554 29568061
PRKDC PARP1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16794079 9398855 21575865 20085707
XRCC6 SIR1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17334224 15205477
EZH2 H31 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 34079125 16431907 16224021 33479123
H31 LMNA â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 26527279 30419336 25948554
KRAS NRAS â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
CBX3 H4 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 30804502 27248496 24981860 21888893 14578449
SUPT16H SSRP1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 5218941 16902406
CBX3 XRCC6 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 34079125 21888893
SSRP1 PARP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 34079125
XRCC6 SSRP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 30585729
XPC PARP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 34079125 28760956
WDR76 PARP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27248496 31353912 25817432
WDR76 GAN â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 31353912
H31 XPC â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 25281560
LCOR EZH2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24981860 26496610 27705803
TCPE TCPH â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22863883 33961781 24981860 22939629 26344197
TCPG TCPH â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 31536960 22863883 33961781 24981860 22939629 26344197
HRAS NRAS â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
DCAF8 CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 31973889 33288900 33961781 31155351 21145461 16949367
H31 PARP1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 20080577 28190768 33961781 32937373 34079125 29568061 20504901
WDR76 HELLS â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33288900 31353912 25817432 33961781
WDR76 TCPG â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31353912 25817432
DNLI3 XRCC6 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 12897160 33961781 30585729
DCAF8 CUL4A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 32235678 31973889 33288900 33961781 31155351 21145461 19295130 16949367
SIR1 EZH2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15684044 22094255 25800736
DNJA1 DNJA2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 33961781 33957083
PARP1 XRCC5 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
RPA1 XRCC6 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CUL4A CUL4B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17041588 31973889 23555860 18593899 33961781 16964240 21145461 30945288 32140073
CUL4B EZH2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 23238014 24292684 27634302
PARP1 DNLI3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34079125 12897160 24778456
H31 PRKDC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20080577 22404984 26527279 29568061 20504901
H4 WDR76 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 27248496 31353912 30804502
WDR76 TCPB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 33961781 27248496 31353912 25817432
H31 XRCC5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20080577 34079125 26527279 29568061 20504901
H31 XRCC6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20080577 29568061 21187428 33961781 34079125 26527279 25281560 20504901
HRAS KRAS â—¼   PHYSICAL_INTERACTION 893.0 0.89 STRING 36370105
CBX1 CBX3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17314413 11336697 16713569 27705803 33961781 21888893 24981860 34079125
PARP1 XRCC6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 24140708 16490787 16794079 14734561 33961781 30585729 34079125 10400681 17283121
PARP1 XRCC5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24140708 16490787 21575865 16794079 14734561 21679440 34079125 10400681 17283121 20085707
XRCC5 PRKDC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15941674 10750018 20023628 17308091 15758953 20085707 33005030 10446239 26496610 19303849 20711232 9312071 26446488 15520013 28154079 28345663 16857680 12393188 22404984 21679440 26344197
XRCC6 PRKDC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20711232 21575865 33005030 28345663 15941674 10064605 26496610 26446488 15520013 10750018 8422676 26175416 22939629 17308091 30585729 19303849 21969602
XRCC6 XRCC5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15910003 19177010 28514442 28035050 14681455 10750018 17159921 25574025 17308091 10984620 11196700 32296183 7699019 33005030 15367688 12145306 19118032 10446239 26496610 19906305 26774286 10207052 21454661 18809223 9488450 26446488 15520013 30021884 22939629 17283121 10219089 10757784 21070772 11493912 21172662 15023334 22863883 22451927 21679440 24981860 10783163 33961781 30585729 26344197
PARP1 XRCC6 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
SSRP1 H4 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 28514442 33961781 21969370 30804502
XRCC6 PRKDC â—¼   RELOCALIZATION ✅ + 0.93 0.93 Signor 19133841
TCPE TCPG â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 33961781 24981860 22939629 26344197
TCPB TCPG â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 22863883 33961781 24981860 22939629 26344197
H31 SSRP1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 28514442 15616580 33961781 26527279 29568061
H31 CBX3 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 24576085 16415788 34133717 26527279 24981860 20011120 15136563 33097091
XRCC6 XRCC5 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 5219440 17159921
XRCC5 XRCC6 â—¼   PHOSPHORYLATION ✅ 0.96 0.96 mint 10783163 5212534
TCPB TCPE â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 22863883 33961781 24981860 30021884 22939629 26344197
TCPB TCPH â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 22863883 33961781 24981860 30021884 22939629 26344197
CBX1 H31 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11882902 16415788 15960974 11242053 15100215 26527279 16622419 29568061 15136563
PRKDC XRCC6 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PRKDC XRCC5 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
H31 H4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 8598932 25416956 30804502 23319141 27248496 16622419 19498464 20080577 14578449 29568061 21724829 19410544 26527279 18571423 25533843 19766566 22828868 14718166 20739937 33961781 20498094 34079125
SSRP1 SUPT16H â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
XRCC5 XRCC6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CBX1 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 15136563 11882902 16622419 20871592 11242053 19111658 15960974 16415788 26527279
CBX3 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15136563 20871592 20011120 24576085 19111658 16415788 26527279
RPA1 CUL4B â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
PARP1 LIG3 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 17088286 17116881 17884153 18524993 19208614 19362533 19364882 19809470 19847258 20056333 20211143 20227374 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 8264637 8978692
PARP1 LIG3 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 17088286 17116881 17884153 18524993 19208614 19362533 19364882 19809470 19847258 20056333 20211143 20227374 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 8264637 8978692
PARP1 SUPT16H â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18406329 16682447
RPA1 CUL4A â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 17720710 12226657 18342608 20129063
E2F4 WDR76 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17531812 11799066
EZH2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18022353 15196462