Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
H2AX XRCC1 â—¼   COLOCALIZATION 2.0 0.8 intact 19851285 7542621
H2AX DNLI3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RFA2 XRCC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 24332808
DNLI3 TOP3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
DNLI3 JMJD4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
WDR76 DNLI3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 27248496
DNLI3 NDUS6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
DNLI3 RSAD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
DNLI3 CG055 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
DNLI3 PPCEL â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
KIF23 DNLI3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31586073 26344197
TYDP1 XRCC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19851285 24981860
H2B1A XRCC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
KIF23 XRCC6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939629 31586073
H2AX H2B1C â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 16522924 34079125
DPOLB DNLI3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DPOLB TYDP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DPOLB APLF â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
RFA2 DNLI3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 24332808
RFA2 XRCC6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 26344197 10064605 24981860 24332808
RFA2 PARP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 24332808
RN146 DNLI3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 21799911
H2B1C DNLI3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25281560 34079125
H31 DNLI3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29568061 33961781 25281560 34079125
H2B1A DNLI3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DNLI3 TYDP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 29523818 15744309
H31 WDR76 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31353912 25281560 27248496
H31 XRCC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29568061 33961781 34079125
APLF TYDP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
H2B1A APLF â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
RN146 XRCC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21825151 21799911
WDR76 XRCC6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31353912 25817432 27248496
H2AX H31 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 26095369 31045206 20587414 20224553 29229926 23319141 16622419
H2AX XRCC6 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15613478 33961781 23145133 20224553 28514442 18406329
PARP1 DPOLB â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 28514442 26186194 20302655 20303835
APLF DNLI3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 17396150 26186194
H2B1A PARP1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 28514442 20525793 26186194
RN146 PARP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28514442 21825151 26186194 21799911
XRCC1 APLF â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 23178593 8412483
WDR76 PARP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 31353912 25817432 27248496
XRCC6 XRCC1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 30585729
APLF PARP1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
DNLI3 XRCC6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 12897160 30585729
H31 PARP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 32937373 28190768 20080577 29568061 20504901 34079125
NEIL1 XRCC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 15260972 16713569
APLF XRCC1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PNKP XRCC1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
H2AX PARP1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28796254 28242625 16377563 27728808 18406329 28514442 20000738 20085707 16522924
DPOLB PNKP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28514442 11163244 26186194 33961781
RFA2 TOP3A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24126761 30279242 24332808
PARP1 DNLI3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12897160 24778456 34079125
H31 XRCC6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 25281560 20080577 21187428 29568061 20504901 26527279 34079125
PARP1 APLF â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26186194 17396150 18172500 20098424 28514442 27067600
DPOLB XRCC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 8978692 26496610 25423885 11467963 26186194 16713569 15367657 11909950 34111398 28514442 29668892 15107487 15520167
PNKP DNLI3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 11163244 30994454 17353931
NEIL1 DNLI3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 15260972 16189514
DNLI3 XRCC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 8264637 24981860 17353931 9136882 30260704 26496610 9705932 11163244 20227374 16713569 11909950 34111398 11352725 29668892
NEIL1 PNKP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16982218 15260972 11163244
XRCC1 NEIL1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16982218 15260972 11163244
XRCC1 PARP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24778456 18971944 12897160 15555565 30260704 34079125 14500814 16713569 9584196 20302655 34111398 15044383 20303835
PARP1 XRCC6 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
APLF XRCC6 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
XRCC6 H2AX â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 22179609 11493912 9512523 11604075 12947387
APLF PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18172500 17396150 20098424
PARP1 XRCC1 â—¼   PHYSICAL_INTERACTION 70.0 1.0 ACSN 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 XRCC1 â—¼   SHARES_COMPLEX 70.0 1.0 ACSN 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9592149 18971944 15555565 19643912 15044383 14500814 16713569 24778456 12897160 20303835 20302655 9584196
XRCC1 PNKP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21637298 17353931 11163244 28821613 19155274 15367657 15385968 26496610 16713569
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368