PARP1
|
APLF
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5219819
17396150
|
APLF
|
PARP2
|
â—¼ ADP_RIBOSYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
8201796
21812934
|
PCNA
|
XPC
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
19279666
7263364
|
APLF
|
H2A2B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
26186194
|
H2A1
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
24463511
|
XPC
|
PARP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
DPOLB
|
SSRP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
26186194
|
SSRP1
|
XPC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
XPC
|
H2A1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
XPC
|
SP16H
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
TYDP1
|
XRCC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24981860
19851285
|
DPOLB
|
H2A2B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
26186194
|
DPOLB
|
APLF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
APLF
|
SSRP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
APLF
|
H2A1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
APLF
|
SP16H
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
APLF
|
XPC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
APLF
|
TYDP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
DPOLB
|
APTX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
DPOLB
|
PARP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
DPOLB
|
XPC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
DHB7
|
DPOLB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
DPOLB
|
DNLI3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
DPOLB
|
ODBB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
DPOLB
|
H2A1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
DPOLB
|
SP16H
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
DPOLB
|
ODBA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
DPOLB
|
TYDP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
DNLI3
|
TYDP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
15744309
29523818
24981860
|
APLF
|
DNLI3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
33961781
26186194
17396150
|
PARP1
|
DPOLB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
28514442
20302655
20303835
26186194
|
PCNA
|
APEX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16189514
11601988
10559261
|
XRCC1
|
APLF
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.86
|
0.86
|
mint
|
23178593
8412483
|
SSRP1
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
28514442
34079125
|
PCNA
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
20129057
20302655
12930846
21690293
20303835
|
DPOLB
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
12063248
25184665
14988403
|
PARP2
|
APLF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
21812934
33961781
26186194
|
XPC
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
33961781
34079125
28760956
|
APLF
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
871.0
|
0.87
|
STRING
|
36370105
|
DPOLB
|
APEX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
9207062
17803946
28986522
|
XRCC1
|
APTX
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.88
|
0.88
|
mint
|
15555565
5217319
|
PARP2
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
19629035
12217960
11948190
|
H2A1
|
SSRP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
24463511
|
H2A1
|
SP16H
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
33961781
24463511
|
APLF
|
XRCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
PNKP
|
XRCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
XRCC1
|
APEX1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
19934257
28986522
16713569
11707423
|
PARP1
|
APLF
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
20098424
17396150
33961781
26186194
18172500
27067600
|
PARP1
|
DNLI3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
34079125
12897160
24778456
|
DPOLB
|
PNKP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11163244
28514442
26186194
33961781
|
APTX
|
XRCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
890.0
|
0.89
|
STRING
|
36370105
|
APLF
|
XRCC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
17396150
17353262
23178593
33961781
26186194
27067600
|
XRCC1
|
APTX
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15380105
16713569
15555565
15044383
26496610
16964241
15367657
|
APTX
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
15044383
16713569
15555565
|
XRCC1
|
PARP1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16713569
15555565
9584196
18971944
24778456
15044383
34111398
14500814
30260704
20302655
12897160
34079125
20303835
|
PNKP
|
XRCC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11163244
15385968
16713569
17353931
21637298
26496610
34111398
15367657
19155274
|
PNKP
|
DNLI3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11163244
17353931
33961781
30994454
|
DPOLB
|
XRCC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
29668892
16713569
25423885
15107487
26496610
15520167
34111398
33961781
26186194
8978692
11467963
15367657
11909950
|
DNLI3
|
XRCC1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11163244
11352725
29668892
16713569
8264637
17353931
9705932
26496610
30260704
34111398
33961781
24981860
20227374
9136882
11909950
|
XRCC1
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16713569
15107487
34111398
30260704
20227374
|
ODBB
|
ODBA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
28514442
15166214
15576032
12902323
33961781
10745006
|
SSRP1
|
SP16H
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
28514442
16902406
22939629
12393879
21055985
22863883
33961781
27173435
24981860
16713563
19214185
30021884
26344197
16682447
|
PARP1
|
APEX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
17548475
11440997
12727891
15135726
10364231
11340072
9804757
|
PCNA
|
APEX1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
4.0
|
1.0
|
Reactome
|
11687589
9214649
11601988
10744741
|
APLF
|
PARP1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
18172500
17396150
20098424
|
PARP1
|
APTX
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
15555565
19643912
15044383
16713569
|
PCNA
|
PARP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
43.0
|
1.0
|
ACSN
|
10858306
11756412
11948190
12637553
14624239
14726013
15703371
15871698
16442856
16697054
16731526
17088286
17116881
18087292
18584027
18809224
19208614
19364882
1974050
19748837
19772495
19847258
20056333
20478261
20510258
20603072
21251944
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PARP1
|
PARP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
60.0
|
1.0
|
ACSN
|
11850621
11877377
12607003
14726013
15459660
15485915
15496928
15549137
15655342
15703371
16697054
17088286
17116881
17965729
18001825
18087292
18171670
18171986
18212739
18584027
18716619
18809224
18835851
19202191
19208614
19217833
19270065
19357644
19364882
19490890
196269035
19772495
19793801
19847258
20021983
20029420
20051983
20064462
20603072
20723763
21037379
21060331
21076181
21270334
21337561
21376743
21818122
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9721205
|
PARP1
|
XRCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
70.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11900249
11948190
12032095
12202749
12637553
12648680
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17884153
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19362533
19364882
19490890
19546231
19748837
19809470
19847258
20027199
20056333
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24210699
24684389
24709898
24976506
8264637
8978692
|
PARP1
|
PARP2
|
â—¼ PROTEIN_INTERACTION
|
|
|
60.0
|
1.0
|
ACSN
|
11850621
11877377
12607003
14726013
15459660
15485915
15496928
15549137
15655342
15703371
16697054
17088286
17116881
17965729
18001825
18087292
18171670
18171986
18212739
18584027
18716619
18809224
18835851
19202191
19208614
19217833
19270065
19357644
19364882
19490890
196269035
19772495
19793801
19847258
20021983
20029420
20051983
20064462
20603072
20723763
21037379
21060331
21076181
21270334
21337561
21376743
21818122
22055391
22469522
22713970
22743550
22921416
23145148
23562323
23568489
24050180
24210699
24684389
24976506
9721205
|
PCNA
|
PARP1
|
â—¼ SHARES_COMPLEX
|
|
|
43.0
|
1.0
|
ACSN
|
10858306
11756412
11948190
12637553
14624239
14726013
15703371
15871698
16442856
16697054
16731526
17088286
17116881
18087292
18584027
18809224
19208614
19364882
1974050
19748837
19772495
19847258
20056333
20478261
20510258
20603072
21251944
21270334
21376743
22021614
22055391
22469522
22713970
22743550
22921416
23145148
23414611
23562323
23568489
24050180
24210699
24684389
24976506
|
PARP1
|
XRCC1
|
â—¼ SHARES_COMPLEX
|
|
|
70.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11900249
11948190
12032095
12202749
12637553
12648680
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17088286
17116323
17116881
17638872
17884153
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19362533
19364882
19490890
19546231
19748837
19809470
19847258
20027199
20056333
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21270334
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
22973052
23082994
23145148
23161013
23253856
23562323
23568489
24036544
24050180
24210699
24684389
24709898
24976506
8264637
8978692
|
PARP1
|
XRCC1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
9592149
18971944
15555565
19643912
15044383
14500814
16713569
24778456
12897160
20303835
20302655
9584196
|
XRCC1
|
PARP2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
54.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17116323
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19490890
19546231
196269035
19748837
19847258
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
23082994
23161013
23253856
24036544
24050180
24709898
8264637
8978692
|
XRCC1
|
PARP2
|
â—¼ SHARES_COMPLEX
|
|
|
54.0
|
1.0
|
ACSN
|
10858306
11163244
11283614
11948190
12032095
12202749
12637553
14726013
15385537
15385968
15703371
16442856
16449207
16697054
17055429
17116323
17638872
17965729
18398454
18524993
18558713
18584027
18809224
19208614
19490890
19546231
196269035
19748837
19847258
20027199
20064462
20211143
20227374
20510258
20603072
20691907
20713526
21251944
21376743
2191300
22055391
22469522
22657828
22713970
22743550
22921416
23082994
23161013
23253856
24036544
24050180
24709898
8264637
8978692
|
XRCC1
|
PNKP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
16.0
|
1.0
|
Omnipath
|
21637298
17353931
11163244
28821613
19155274
15367657
15385968
26496610
16713569
|
PCNA
|
XRCC1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
37.0
|
1.0
|
ACSN
|
11756412
11900249
12648680
12930902
14624239
14726013
15189466
15459660
15703371
16697054
17116885
17296725
17582221
17652783
17884153
18087292
18196958
18584027
18677104
18809224
19258535
1974050
19772495
19793801
19809470
19847258
20211143
20227374
20478261
21282463
21376743
22021614
22743550
23414611
24050180
8264637
8978692
|
PCNA
|
XRCC1
|
â—¼ SHARES_COMPLEX
|
|
|
37.0
|
1.0
|
ACSN
|
11756412
11900249
12648680
12930902
14624239
14726013
15189466
15459660
15703371
16697054
17116885
17296725
17582221
17652783
17884153
18087292
18196958
18584027
18677104
18809224
19258535
1974050
19772495
19793801
19809470
19847258
20211143
20227374
20478261
21282463
21376743
22021614
22743550
23414611
24050180
8264637
8978692
|