Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
PCNA XPC â—¼   COLOCALIZATION 2.0 0.8 intact 19279666 7263364
APLF PARP2 â—¼   ADP_RIBOSYLATION ✅ 2.0 0.8 intact 8201796 21812934
DPOLB SSRP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
DPOLB H2A2B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
XPC SP16H â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TYDP1 XRCC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19851285 24981860
XPC H2A1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
H2A1 PARP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 24463511
APLF H2A2B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
XPC PARP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SSRP1 XPC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DPOLB ODBA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DPOLB DNLI3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DPOLB XPC â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DPOLB TYDP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DPOLB APTX â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DPOLB APLF â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DPOLB PARP2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DPOLB ODBB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DPOLB H2A1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DPOLB SP16H â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DHB7 DPOLB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DNLI3 TYDP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 24981860 29523818 15744309
APLF SP16H â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
APLF TYDP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
APLF H2A1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
APLF SSRP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
APLF XPC â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PARP1 DPOLB â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 28514442 26186194 20302655 20303835
APLF DNLI3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 17396150 26186194
DPOLB PCNA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25184665 14988403 12063248
PCNA APEX1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10559261 11601988 16189514
XRCC1 APLF â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 23178593 8412483
SSRP1 PARP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28514442 34079125
PARP2 APLF â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 21812934 26186194
XPC PARP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 34079125 28760956
APLF PARP1 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
DPOLB APEX1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17803946 28986522 9207062
H2A1 SP16H â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 24463511
H2A1 SSRP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 24463511
PARP2 PARP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12217960 11948190 19629035
APLF XRCC1 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
PNKP XRCC1 â—¼   PHYSICAL_INTERACTION 886.0 0.88 STRING 36370105
DPOLB PNKP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28514442 11163244 26186194 33961781
PARP1 DNLI3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12897160 24778456 34079125
XRCC1 APEX1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28986522 19934257 11707423 16713569
PARP1 APLF â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26186194 17396150 18172500 20098424 28514442 27067600
APTX XRCC1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
XRCC1 PCNA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 30260704 20227374 16713569 34111398 15107487
DPOLB XRCC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 8978692 26496610 25423885 11467963 26186194 16713569 15367657 11909950 34111398 28514442 29668892 15107487 15520167
PNKP DNLI3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 11163244 30994454 17353931
DNLI3 XRCC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 8264637 24981860 17353931 9136882 30260704 26496610 9705932 11163244 20227374 16713569 11909950 34111398 11352725 29668892
ODBB ODBA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 15166214 15576032 12902323 28514442 10745006
APTX PARP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15555565 16713569 15044383
XRCC1 APTX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15380105 15555565 26496610 16964241 15367657 16713569 15044383
XRCC1 PARP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24778456 18971944 12897160 15555565 30260704 34079125 14500814 16713569 9584196 20302655 34111398 15044383 20303835
SSRP1 SP16H â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 27173435 24981860 19214185 26344197 16682447 16713563 22939629 16902406 21055985 28514442 22863883 12393879 30021884
PCNA PARP1 â—¼   PHYSICAL_INTERACTION 43.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PCNA XRCC1 â—¼   PHYSICAL_INTERACTION 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
PCNA XRCC1 â—¼   SHARES_COMPLEX 37.0 1.0 ACSN 11756412 11900249 12648680 12930902 14624239 14726013 15189466 15459660 15703371 16697054 17116885 17296725 17582221 17652783 17884153 18087292 18196958 18584027 18677104 18809224 19258535 1974050 19772495 19793801 19809470 19847258 20211143 20227374 20478261 21282463 21376743 22021614 22743550 23414611 24050180 8264637 8978692
PCNA PARP1 â—¼   SHARES_COMPLEX 43.0 1.0 ACSN 10858306 11756412 11948190 12637553 14624239 14726013 15703371 15871698 16442856 16697054 16731526 17088286 17116881 18087292 18584027 18809224 19208614 19364882 1974050 19748837 19772495 19847258 20056333 20478261 20510258 20603072 21251944 21270334 21376743 22021614 22055391 22469522 22713970 22743550 22921416 23145148 23414611 23562323 23568489 24050180 24210699 24684389 24976506
PARP1 APEX1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 17548475 11440997 12727891 15135726 10364231 11340072 9804757
APLF PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18172500 17396150 20098424
PARP1 APTX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15555565 19643912 15044383 16713569
PARP1 XRCC1 â—¼   PHYSICAL_INTERACTION 70.0 1.0 ACSN 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 PARP2 â—¼   PHYSICAL_INTERACTION 60.0 1.0 ACSN 11850621 11877377 12607003 14726013 15459660 15485915 15496928 15549137 15655342 15703371 16697054 17088286 17116881 17965729 18001825 18087292 18171670 18171986 18212739 18584027 18716619 18809224 18835851 19202191 19208614 19217833 19270065 19357644 19364882 19490890 196269035 19772495 19793801 19847258 20021983 20029420 20051983 20064462 20603072 20723763 21037379 21060331 21076181 21270334 21337561 21376743 21818122 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 9721205
PARP1 XRCC1 â—¼   SHARES_COMPLEX 70.0 1.0 ACSN 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9592149 18971944 15555565 19643912 15044383 14500814 16713569 24778456 12897160 20303835 20302655 9584196
XRCC1 PARP2 â—¼   PHYSICAL_INTERACTION 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
XRCC1 PARP2 â—¼   SHARES_COMPLEX 54.0 1.0 ACSN 10858306 11163244 11283614 11948190 12032095 12202749 12637553 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17116323 17638872 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19490890 19546231 196269035 19748837 19847258 20027199 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 23082994 23161013 23253856 24036544 24050180 24709898 8264637 8978692
XRCC1 PNKP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 21637298 17353931 11163244 28821613 19155274 15367657 15385968 26496610 16713569
XPC XPC â—¼   KO_DOWN_REGULATES ✅ - -3.23 3.22 PKG 28854368
PARP2 PARP2 â—¼   KO_DOWN_REGULATES ✅ - -6.68 6.67 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368