Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
XRCC4 APTX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15380105 5217198
SYT17 APTX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
MBP APTX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
MAPKBP1 APTX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ZNF639 APTX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
TRIM37 APTX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
HIVEP1 APTX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PICK1 APTX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
CNTROB APTX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
CEP350 APTX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
TSPYL2 APTX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
CALCOCO1 APTX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
TP53 BAD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17000778 22869582
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
PARP1 HIVEP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TP53 NCL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22103682 8291914
PRKCG PICK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
PICK1 PRKCG â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
TP53 PRKCG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10614633 9895308
APTX BAD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
APTX KIF3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
APTX XRCC4 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
DPOLB APTX â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
PARP1 DPOLB â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 28514442 26186194 20302655 20303835
HSPA4 TP53 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
ESR1 HSPA4 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
APTX XRCC1 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
SYT17 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
DPOLB XRCC1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 8978692 26496610 25423885 11467963 26186194 16713569 15367657 11909950 34111398 28514442 29668892 15107487 15520167
APTX PARP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15555565 16713569 15044383
XRCC1 APTX â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15380105 15555565 26496610 16964241 15367657 16713569 15044383
XRCC1 PARP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24778456 18971944 12897160 15555565 30260704 34079125 14500814 16713569 9584196 20302655 34111398 15044383 20303835
LIG3 XRCC1 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
PARP1 APTX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15555565 19643912 15044383 16713569
PRKCG APTX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19561170
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
XRCC1 LIG3 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 17088286 17116881 17884153 18524993 19208614 19362533 19364882 19809470 19847258 20056333 20211143 20227374 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 8264637 8978692
PARP1 LIG3 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 17088286 17116881 17884153 18524993 19208614 19362533 19364882 19809470 19847258 20056333 20211143 20227374 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 8264637 8978692
PARP1 LIG3 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 11900249 12648680 14726013 15703371 16697054 17088286 17116881 17884153 18524993 19208614 19362533 19364882 19809470 19847258 20056333 20211143 20227374 20603072 21270334 21376743 22055391 22469522 22713970 22743550 22921416 23145148 23562323 23568489 24050180 24210699 24684389 24976506 8264637 8978692
LIG3 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 9705932 20227374 17353931 11163244 26496610 16713569 8264637 11352725 9136882
PARP1 XRCC1 â—¼   PHYSICAL_INTERACTION 70.0 1.0 ACSN 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 XRCC1 â—¼   SHARES_COMPLEX 70.0 1.0 ACSN 10858306 11163244 11283614 11900249 11948190 12032095 12202749 12637553 12648680 14726013 15385537 15385968 15703371 16442856 16449207 16697054 17055429 17088286 17116323 17116881 17638872 17884153 17965729 18398454 18524993 18558713 18584027 18809224 19208614 19362533 19364882 19490890 19546231 19748837 19809470 19847258 20027199 20056333 20064462 20211143 20227374 20510258 20603072 20691907 20713526 21251944 21270334 21376743 2191300 22055391 22469522 22657828 22713970 22743550 22921416 22973052 23082994 23145148 23161013 23253856 23562323 23568489 24036544 24050180 24210699 24684389 24709898 24976506 8264637 8978692
PARP1 XRCC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 9592149 18971944 15555565 19643912 15044383 14500814 16713569 24778456 12897160 20303835 20302655 9584196
PARP1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9312059 17891139 15044383 12898523 14627987 16713569 9565608
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368