Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
DYRK2 GLI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18455992
MFHAS1 STN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
RBSN RAB4A â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
RAN H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
GRB2 H4C6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
H4C6 RAN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H4C6 KIF3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3C14 H3-3B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3C14 KIF3A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MFHAS1 PSME3IP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
DCTN3 ACTR1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15473859 15738427
SMO ARRB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15618519 23074268
ARRB1 SMO â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 15618519
ARRB2 KIF3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23074268 16908539
MFHAS1 GAK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
KIF7 GLI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19549984
KIF7 GLI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19549984 19592253
GRB2 TUBA1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
MAPRE3 MAPRE1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
MFHAS1 NEK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
PRKCI PARD6A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5213720 11257119
ACTR1A DCTN3 â—¼   PHYSICAL_INTERACTION 805.0 0.8 STRING 36370105
PARD6A PARD3 â—¼   PHYSICAL_INTERACTION ✅ 0.81 0.81 mint 5213720 11257119
KIF3A KIF3B â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
EXOC3 IFT20 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KBP KIF3C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KIF3A TRI29 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KIF3A H33 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KIF3A PPAP â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KIF3A SBP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KIF3A DUS14 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KIF3A SPB5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KBP KIF3B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HENMT KIF3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZN785 KIF7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZN785 KIF3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZN785 SUFU â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KIF3A LRC15 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TNR8 KIF3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LX15B KIF3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KIF3A MFHA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KIF3A PKP3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KIF3A LYPA2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KIF3A HPHL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KIF3A PPCE â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KIF3A FA26D â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
APTX KIF3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KIF3A ATG9B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KIF3A DSG4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EXOC3 PKD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EXOC3 KIF3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EXOC3 SCLT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GLI2 KIF7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 35140242
TYW3 KIF3A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KIF3A PADI3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KIF3A PKP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KIF3A LYG2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GLI2 SUFU â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
STN1 KIF3A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
KIF3C DISC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17043677 31413325 90000000
KIF3C KIFA3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
KIFA3 DISC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17043677 31413325 90000000
DTBP1 KIF3A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DTBP1 AP3S1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DTBP1 EXOC3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DTBP1 AP3B1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DTBP1 AP3D1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
KBP KIF3A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 27173435
CASP1 KIF3A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DCTN1 DISC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17043677 31413325 90000000
KIF3A DISC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17043677 31413325 90000000
MED4 IFT20 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 25416956 29615496 25281560
KIF3B RAB4A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12832475
ACTR1A DCTN3 â—¼   CORRELATES + 0.85 0.85 CCLE 31978347
DTBP1 IFT20 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25416956 27173435
DCTN1 MAPRE3 â—¼   PHYSICAL_INTERACTION 864.0 0.86 STRING 36370105
MAPRE3 TUBA1B â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
DISC1 IFT20 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 17043677 31413325 32296183
KIF3A KIF3C â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
DCTN1 GRB2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 8955163 16189514
SUFU GLI3 â—¼   RELOCALIZATION ✅ - 0.88 0.88 Signor 10564661
SUFU GLI2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 35140242 12068298 10564661
AP3B1 AP3D1 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
DCTN1 DCTN3 â—¼   CORRELATES + 0.89 0.89 CCLE 31978347
KIF3A KIFA3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 27173435 26344197 26496610 16298999 17825299 28514442
ARRB2 ARRB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17353931 24069330 28514442 17620599
SUFU GLI2 â—¼   RELOCALIZATION ✅ - 0.9 0.9 Signor 16316410
SUFU GLI3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 29515120 24311597 35140242 10564661
RAB23 KIF3A â—¼   REGULATES ✅ 3.0 0.9 ACSN 11449277 18497258 20375059
KIF3A PKD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17283055 16950792 17008358
RAB23 KIF3B â—¼   REGULATES ✅ 3.0 0.9 ACSN 11449277 18497258 20375059
RAB23 SMO â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11449277 20375059 18497258
RAB23 SMO â—¼   REGULATES ✅ 3.0 0.9 ACSN 11449277 18497258 20375059
ACTR1A DCTN1 â—¼   CORRELATES + 0.9 0.9 CCLE 31978347
KIF3C KIFAP3 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
DCTN1 DCTN3 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
KIF3A RPGR â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
AP3B1 AP3S1 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
DCTN1 RPGR â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
GLI3 SUFU â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
KIF3B KIFA3 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 27173435 26496610 9506951 16298999 16713569 28514442
ACTR1A DCTN1 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
AP3S1 AP3D1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 15469849 23144738 26344197 28514442 22863883
DCTN1 MAPRE1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
KIF3B KIFAP3 â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
KIF3A KIFAP3 â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
PARD3 PARD6A â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
AP3D1 AP3S1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
AP3B1 AP3D1 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
PARD6A PRKCI â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
RAN RANBP2 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
MAPRE1 MAPRE3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PARD3 PRKCI â—¼   PHYSICAL_INTERACTION 996.0 0.99 STRING 36370105
KIF3B IFT20 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 24596149 24616010 18852297 19450523 17312020 23990561
KIF3C IFT20 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 24596149 24616010 18852297 19450523 17312020 23990561
IFT20 KIFAP3 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 24596149 24616010 18852297 19450523 17312020 23990561
IFT20 KIF3A â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 24596149 24616010 18852297 19450523 17312020 23990561
MAP3K10 DYRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18455992 11274345
DYRK2 GLI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 19685005 21965663 21709260 12063245 18794343 25660620 9932450 18455992
AP3B1 KIF3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19934039
SMO ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15618519 23074268
SMO GLI2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 17641202 18820483 19081070 20215540 23031257
GLI2 ULK3 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 20643644 22391301 18827223 12138125 12050670 19878745 18455992
KIF3A GLI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14603322 20643644 20956384 11208056
GLI3 GLI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 21234400 20562908 9216996 19032343 12435627 16406505 19114989 16880536 16054035 11001584 17000779 16169709 16413481 15087129 16396903 19809516 20107231
SMO GLI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20016067 20643644 20956384 21209912 18820483 17641202 17688959 18997815 19549984 19592253
SUFU GLI2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20463034 10564661 35044719 16316410
GLI3 ULK3 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 20643644 22391301 18827223 12138125 12050670 19878745 18455992
SMO GLI3 â—¼   DOWN_REGULATES ✅ - 5.0 1.0 ACSN 17641202 18820483 19081070 20215540 23031257
SUFU GLI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 17145710 23331499 24311597 20463034 10433919 20083481 10564661
KIF3A GLI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 14603322 20643644 20956384 11208056
SMO GLI3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20016067 20643644 20956384 21209912 18820483 17641202 17688959 18997815 19549984 19592253
SMO KIF3A â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 11208056 11226259 11449277 14603322 15618519 17641202 18497258 18820483 19081070 19565474 19853559 20215540 20375059 23031257
KIF3A KIF3B â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11208056 11226259 11449277 14603322 15618519 15852005 17641202 18497258 18820483 19081070 19565474 19718039 19853559 20215540 20375059 20643644 20956384 21602792 23031257
SMO KIF3A â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 11208056 11226259 11449277 14603322 15618519 17641202 18497258 18820483 19081070 19565474 19853559 20215540 20375059 23031257
KIF3A SUFU â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11208056 14603322 20643644 20956384
KIF3A KIF7 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11208056 14603322 20643644 20956384
KIF3A ULK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11208056 14603322 20643644 20956384
SMO KIF3B â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 11208056 11226259 11449277 14603322 15618519 17641202 18497258 18820483 19081070 19565474 19853559 20215540 20375059 23031257
SMO KIF3B â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 11208056 11226259 11449277 14603322 15618519 17641202 18497258 18820483 19081070 19565474 19853559 20215540 20375059 23031257
KIF3B KIF7 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11208056 14603322 20643644 20956384
KIF3B SUFU â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11208056 14603322 20643644 20956384
KIF3B ULK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11208056 14603322 20643644 20956384
SUFU KIF7 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 0643644 11001584 17845852 18497536 19055941 19549984 19592253 19666503 19684112 19878745 19906571 20643644 20956384 21209912
ULK3 KIF7 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 0643644 11001584 17845852 18497536 19055941 19549984 19592253 19666503 19684112 19878745 19906571 20643644 20956384 21209912
SUFU KIF7 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 0643644 11001584 17845852 18497536 19055941 19549984 19592253 19666503 19684112 19878745 19906571 20643644 20956384 21209912
ULK3 KIF7 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 0643644 11001584 17845852 18497536 19055941 19549984 19592253 19666503 19684112 19878745 19906571 20643644 20956384 21209912
SMO KIF7 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 17641202 17688959 18820483 18997815 19081070 19549984 19592253 20016067 20215540 20643644 20956384 21209912 23031257
SMO KIF7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 20016067 20643644 20956384 19666503 21209912 18820483 17641202 17688959 18997815 19549984 19592253
PRKCI PARD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17145710 14676191 22579248 27554858
RANBP2 RAN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 21988832 24855949 10078529 7603572 20547757 11470507 10318915
SMO SUFU â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 17641202 17688959 18820483 18997815 19081070 19549984 19592253 20016067 20215540 20643644 20956384 21209912 23031257
SMO ULK3 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 17641202 17688959 18820483 18997815 19081070 19549984 19592253 20016067 20215540 20643644 20956384 21209912 23031257
SMO SUFU â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 20016067 20643644 20956384 22114142 21209912 18820483 17641202 17688959 18997815 19549984 19592253
SUFU ULK3 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 0643644 11001584 16371461 16611981 16651270 17845852 18455992 18497536 18813803 19055941 19549984 19592253 19666503 19684112 19878745 19906571 20643644 20956384 21209912
SUFU ULK3 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 0643644 11001584 16371461 16611981 16651270 17845852 18455992 18497536 18813803 19055941 19549984 19592253 19666503 19684112 19878745 19906571 20643644 20956384 21209912
SUFU ULK3 â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 0643644 11001584 16371461 16611981 16651270 17845852 18455992 18497536 18813803 19055941 19549984 19592253 19666503 19684112 19878745 19906571 20643644 20956384 21209912