Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SMAD2 GSC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16055724 9702197
SMAD9 SMAD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8893010 11779505
SMAD1 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD9 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD9 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15231748
SMAD9 SMAD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
SMAD9 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8893010 11779505
FAN DSG4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RB11B DSG4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
RM38 DSG4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SETB2 DSG4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
IL31R DSG4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
S22A9 DSG4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MAS DSG4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LPCT4 DSG4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GRP4 DSG4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CB077 DSG4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
COASY DSG4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
CPLX3 DSG4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RPN2 DSG4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZMAT4 DSG4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SYT16 DSG4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FBXL4 DSG4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FOXP2 DSG4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
REEP2 DSG4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KIF3A DSG4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GSC DSG4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
OAZ3 DSG4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SMAD1 LEF1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 10890911 15750622
SMAD2 SMAD9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 15231748
SMRD1 DSG4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
O51E2 DSG4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
IFIX DSG4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
B3GL1 DSG4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CA049 DSG4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SIA7C DSG4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
MTNB DSG4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TFG DSG4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
VTI1B DSG4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PMM1 DSG4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SGOL2 DSG4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SMAD9 DSG4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SMAD1 SMAD3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15761153 9111321 18729074
SMAD4 SMAD5 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
SMAD5 SMAD4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10531362 16189514 15231748 16516194
SMAD3 SMAD9 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
SMAD2 LEF1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10890911 15750622
SMAD3 LEF1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10890911 15750622
SMAD2 SMAD1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28205554 28628118 9111321 18729074
SMAD2 SMAD3 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
SMAD2 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18729074 9111321
SMAD4 SMAD1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 17183365 5219486
SMAD4 SMAD9 â—¼   PHYSICAL_INTERACTION 950.0 0.95 STRING 36370105
SMAD1 SMAD4 â—¼   PHYSICAL_INTERACTION 960.0 0.96 STRING 36370105
SMAD2 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
SMAD3 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
SMAD3 LEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 10890911 21071413 18988627
SMAD4 LEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 10890911 21071413 18988627
SMAD2 LEF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 10890911 21071413 18988627
SMAD1 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 34.0 1.0 Omnipath 17183365 9436979 24412244 11779505 31467278 21454478 10531362 15231748 12167862 23331499 21071413 11700304 12874272 16189514 18988627 20957627 9111321 15761153 32296183 26555259 14701756 14534577
SMAD3 SMAD2 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
SMAD4 SMAD2 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11399519 11792802 11875494 12193690 12545156 12702545 12809600 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 17055429 17260466 17550342 17689680 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23390297 23784029 23869868 6357187 8515656 8871614 9312026 9389648 9618481 9670020
SMAD2 SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16052471 11376804 11456453 9812998
SMAD2 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 110.0 1.0 Omnipath 15613484 17145710 25609649 15817471 20211142 21532621 24584437 18729074 23788427 12419246 16916642 9288972 9892009 21454478 17510063 10531362 15231748 11027280 12167862 21988832 9389648 23331499 12543979 18568018 21071413 19135894 18511908 15467747 12808092 11927552 25514493 15350224 18988627 12732634 10878024 9111321 9311995 9346908 10199400 11264182 12957874 11114293 15761153 11274206 12621041 17272273 24157709 26555259 12374795 22442258 10781087 15922743 11102446 17591701 18783722 16751102 19139564 19917253 9346966 21297662 17283070 12794086
SMAD2 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 26186194 12543979 9111321 15084259 9311995 25878769 18729074 12700238
SMAD4 SMAD3 â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 SMAD3 â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD3 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 104.0 1.0 Omnipath 25609649 9843571 15084259 20211142 21532621 24584437 18729074 23788427 12419246 18923419 9892009 19768112 10531362 15231748 9679060 12167862 21988832 12150994 23331499 12543979 18568018 21071413 19135894 15467747 25502805 9732876 11927552 16189514 12917407 25514493 15350224 10995777 18988627 10092624 12732634 25910212 10878024 9111321 20564330 27107012 9311995 12957874 20142324 11114293 32296183 15588252 15761153 24157709 26555259 29892012 17469184 22442258 16714330 21597466 15922743 22045334 17591701 24382352 22310290 19139564 19917253 29997244 31515488 28115363 10942775 21297662 17283070 12794086
SMAD5 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 20957627 23331499 14534577 16516194 16189514 10531362 15231748
SMAD9 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20957627 25502805 10583507 31515488 16189514 15231748