Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
E2F1 DNMT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18319725 15867357
E2F1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11799067
E2F1 HIC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19491197 19015639
E2F1 HIC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19491197
EP300 FOXO3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11896584
EP300 WRN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20428248
MYC EZH2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21941025 19197161
EP300 FOXO1 â—¼   PHYSICAL_INTERACTION 807.0 0.8 STRING 36370105
TIF1B P53 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 20858735 17056014 32807901 20864041
SIR1 TIF1B â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 18235501 22542455 25905708
EP300 NPM â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 16107701 29746960 33742100
JUN P53 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 31182485
ZN669 TIF1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZN785 TIF1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RL6 SIR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
SIR1 HS90A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22542455 26496610
ZN263 SIR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NPM SIR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34079125 20431927
WDR76 SIR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 31353912
HNF4A SIR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20375098 35140242
ZN785 SIR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
IRS1 SIR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17901049 21241768
Z354C SIR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZN669 SIR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SOST SIR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CERKL SIR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VWA3B SIR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RBFA SIR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TBCC1 SIR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CLK3 SIR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
APEX2 SIR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZN550 SIR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SIR1 HDAC4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16166628 23417673
SIR1 SUZ12 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15684044 22094255
MYC RS2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
MYC DNMT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MYC JUN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 20232342
JUN XRCC6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 30585729
FGF10 SIR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
MTA1 SIR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
XRCC6 P53 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11751391 15782130 32807901
AK1D1 SIR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
HXB5 SIR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SFRP4 SIR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
IRS2 SIR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17901049 21241768
CWC15 SIR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TAD2B SIR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
RS2 SIR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ZBT38 SIR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SIR1 TULP3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 23382074 33187986
WDR76 XRCC6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31353912 25817432 27248496
ATG7 FOXO1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
RB SIR1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 17620057 16892051
RB P53 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20871633 8083962
TF65 P53 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 17434128 28205554 28628118
SUV91 DNMT1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12711675 17085482
DNM3B SIR1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 27728808 22094255
MYC HS90A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28914785 29467282 12644583
NCOR1 SIR1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15175761 18829436
XRCC6 SIR1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 17334224 15205477
SIR1 HIC1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16269335 23417673 23704280 17283066 22510409
FOXO3 EP300 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25609649 11896584 19592618
EP300 XRCC6 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21988832 15023334 33742100
DNMT1 MTA1 â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
DNMT1 EZH2 â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
Z354C TIF1B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 19850934 32869873
NCOR1 TIF1B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11013263 14761981
JUN HS90A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 20936779 25609649 20195357
HS90A CLK3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 22939624 32707033
E2F1 SIR1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 16892051 19188449 24112038
SIR1 DBC1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 18235501 18235502 21030595 26113041 23382074 22446626
E2F1 EP300 â—¼   PHYSICAL_INTERACTION 857.0 0.85 STRING 36370105
FOXO3 P53 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14976264 27886165 25241761 18824006
EZH2 TIF1B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 27634302 28068325 32956422 24457600
EP300 SRBP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20817729 12640139 20534441 14615581 10235267
SRBP1 SIR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20595232 20817729
MYC UBP22 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28160502 35140242 30415952 18206973 31511647
UBP22 TAD2B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19615732 24981860
SIR1 JUN â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25609649 18823944 20042607 23382074
WRN XRCC6 â—¼   PHOSPHORYLATION ✅ 0.86 0.86 mint 10783163 5212534
RB EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17620057 11433299 31753913 16878158
SIR1 SUV91 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 18004385 19218236
MYC TIF1B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17314511 29467282 17353931
DNM3B EZH2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25531315 24074865 16357870 27728808 22094255
CDKL1 SIR1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 23602568 26186194
SIR1 MTOR â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21471201 26453307
SIR1 FOXO1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 18235501 15220471 16154098 15692560 22013015
MYC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12776737 16287840 32140074 15616592 16126174 17157259
HNF4A FOXO1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12519792 19740748
SIR1 CSK21 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19680552 20439735 19236849 21968188
MYC TF65 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15616592 12027803 28205554 28628118 16713569
MYC SIR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21807113 22190494
DNMT1 SIR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21947282 22094255
ATG7 SIR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18296641 31072129
SIR1 EZH2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25800736 15684044 22094255
SIR1 WRN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18203716 19343720
SIR1 EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20660480 19047049 15632193
MTA1 P53 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12920132 16713569 20071335 17914590 16189514 32807901 19837670
MYC RB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29467282 7838535 30415952 28205554 28628118
SUV91 RB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11533237 11484059 16189514
RB JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9545246 10026157
CSK21 P53 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 15358769 10884347 10747897 12628923 10348343 24725084 25241761 11883897 22975381 11709713 10951572 12393879 23443559
MYC P53 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21150319 30415952 28205554 28628118
P53 E2F1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24076372 11739724 8557038
SIR1 TF65 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21081649 15152190 17041012
TF65 NPM â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19074833 21988832 14743216
RL6 NPM â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26186194 22939629 26496610 19293945
UBP22 SIR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 34226501 28166203 19615732 23382074 22542455 28417539 32763411 31502386 34266953 27183383
AROS SIR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26113041 17964266 23382074 24681097
SIR1 K1967 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18235501 25361978 22190494 18235502 33459133 22735644
SIR1 FOXO3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20733005 14976264 21713995 15126506
MYC XRCC6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30415952 17314511 29467282
RB DNMT1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11847125 10888886 23280764
RB E2F1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10869426 15485920 8255752 16374512 16360038 35140242 9400991 9315635 24981860 21085491 16496386 11090181 31130363 9501179 25257171 10891495 19249677 11713253 15837424 18216119 16249186 12096339 19477924 20871633 22768064 9632788 11839806 12502741 8458319 10499802 7958924 1388726 10207050 18391203 7828850 9219533 8449399 22078878 16766265 23472054 29521627 15485814 30867845 15619620 12963846 12947005 17380128 11470869 12397079 8657117 12598654 9422723 15670817 9553123 12401786 28074012 28542143 7739537 8626527 8346196 11583618 8896460 8816798 9125176 9468140 19058874 8230483 10393912 23001041
HNF4A P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 35140242 11818510 16713569 28514442
NPM P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15964625 31152661 15310764 32807901 12080348 16376884 15082766 16740634 23443559 15144954
EP300 P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 29706626 25156994 12724314 23728348 16543236 12501250 9652736 9194564 18243116 9194565 19339993 16678111 16611888 11359905 11782467 12162806 14612423 14759370 15186775 15664194 9288740 23402884 17452980 24157709 9891054 12499368 19234109 27818144 16537920 17977830 15295102 10518217 16713569 26625199 16928824 11070080 17906639 23870121 23796514 15558054 17438265 25867071 17189186 18485870 11907332 15542844 19217391 32807901 16438982 31167125 15337767 10490106 22731250 12690203 25288747 18612383 23329847 24821727 26302407 9809062 16959611 22074660 19218448 16782091 23880760 33196849 25753752 28757384 18391200 16024799 25651062 16135789 22013068 11433299 9744860 10601022 21187340 11804596 23307557 10942770 15509808 20234175 21471221 26229107 19805293 22266186 15965232 23010591
WRN P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11427532 15735006 12080066 16713569 11399766
P53 HS90A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15358769 31152661 30911017 32097779 15004035 11707401 10557093 32807901 11507088 11297531 12427754 16713569 21268072 21460846 22939624 15001357 16189514 23443559
P53 SIR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18235501 17964266 18235502 15205477 21245319 11672523 18753379 21149449 22735644 12006491 22389628 22689577
CSK21 JUN â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25609649 9685505 1516134 12628923
CSK21 HS90A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19740745 2492519 22113938 16335536 7794926 22824801
DNM3B DNMT1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15120635 29691401 21406692 12867029 27728808 12145218 22094255
EP300 TF65 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11585920 29706626 15192014 23999430 18280497 20333651 9096323 12471036 18397880 16135789 25400040 20154269 21187066 12419806 17692505 16713569 25074812 12403783 23811396 11567019 21483817 10235267 12456660 12960163 16291753 17982102 15171256 11533489
MYC K1967 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17353931 22190494 29467282 30415952 17314511
FOXO1 ATG7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 30689742 20543840
E2F1 DNMT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24502362 17575144 15867357
EP300 E2F1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10753885 15123636 15126619
E2F1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11564866 18319725 90001421
HDAC4 NCOR1 â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
EP300 JUN â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
WRN XRCC6 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
SUZ12 EZH2 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 24981860
EZH2 SUZ12 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
MTA1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21734722 17666529 15576399 22761862 22290435 19923891 20682799
E2F1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 8208548 2721961 7753559 11705881 24038073 8355712 1549358 1567856 12629508
E2F1 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 18319725 14532106
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
FOXO3 FOXO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19244250 16100571 18202312 23509296 19690465
HNF4A FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12519792 19740748
HNF4A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12591729 23714368 19966299 15024077
MTOR IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 22570710 15952059 19561084 21282364 25973388 14769130 11287630 9335553 17698034 20863384
JUN IRS2 â—¼   ENZYMATIC_REACTION ✅ 37.0 1.0 ACSN 11274345 11955436 11967263 12051714 12417340 15001769 15279786 15337521 16007092 16039586 16510874 17143292 17303408 17439715 17565603 17660363 17936032 18590585 19619488 19623618 19879327 20006983 20144767 20530697 20705860 20920541 21285352 22020335 23296977 23343194 24023259 25730849 26587781 7542250 7575488 8545107 8666229
JUN MYC â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 11274345 11929833 11955436 11967263 12051714 15001769 15576399 15768032 15806138 16007074 16039586 16169192 16510874 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19619488 19623618 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22290435 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
JUN MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21835891 8276360 1774959 2498162 21607323 20410304 14523011 18037408
JUN MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 15806138 16510874 22290435 18627596 19623618 11929833 23343194 15768032 22761862 17050667 16039586 20122174 17291450 20920541 17143292 20006983 17439715 15576399 21767405 23306204 8545107 22705350 18347071 16007074 16169192 21285352 20530697 19619488 11274345
MTOR MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 12150925 12408816 12906785 15755954 16469695 17604271 17680028 18372248 18492954 19022819 19446321 19568798 19706736 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
WRN WRN â—¼   KO_DOWN_REGULATES ✅ - -3.6 3.59 PKG 28854368