Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CDK2 WEE1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 1396589 11585773
PSMD6 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
VCP TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
HSPA5 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
VCP HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
ACTB HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
UBQLN2 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT TAGLN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HTT DLST â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SMN1 TAGLN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TAGLN2 GDAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PSMD6 VCP â—¼   PHYSICAL_INTERACTION 852.0 0.85 STRING 36370105
TRAF6 PSMD6 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17353931 14743216
LRRK2 PSMD6 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31046837 24725412
DNM1L LRRK2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
HTT VCP â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
CFTR VCP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
H2AX ACTB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
SMN1 ACTB â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
LRRK2 DNM1L â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22228096 22639965 24282027 29541021 23813973
MAPK1 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10777545 17081983 21098032 9430721 12110590 20068231 19690332 15304344 19413330 10878576 15192015 7737129 18669648 19647037
MAPK13 ATF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 15187187 19436832 9207191 10581204 15140942 20506250 21614932 19135240 16393692 12244047 11274345
WEE1 CDK2 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 15279786 17303408 17660363 18590585 23508805 23897299 7575488
CDK2 BMI1 â—¼   UP_REGULATES ✅ + 32.0 1.0 ACSN 11274345 11283614 12545156 14536078 15147722 15155580 15279786 17055429 17303408 17550342 17558397 17660363 17873522 18590585 18636226 20027199 20237412 20551172 20581311 20713526 20818389 21406394 21733352 2191300 21919891 22067385 23140366 23869868 25002027 28536364 7575488 9618481
MAPK1 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10962581 12359725
WEE1 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 58.0 1.0 Omnipath 17303408 24927813 25458954 19690332 16497976 18083107 30266203 15279786 15302935 15632290 12181445 17389395 17095507 7575488 19534553 7743995 18452278 12912980 22999936 21900495 24419005 1396589 18590585 10896159 18691976 15144186 20462953 12972555 16177568 17660363 17192257 11029659 34156324 17545210 19369195 26240362 19664994 11585773 25361894 20465818 17016520 15659558 18212344 13678583
MAPK13 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 12738796 18039929 11274345 15187187
MAPK1 TAGLN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 30041673
VCAM1 ITGA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 22623428 19738201 11751331