Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
H1-5 GDF9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
GDF9 KIF22 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
H1-4 H1-5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 H1-5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-5 KIF22 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-5 MYBL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-5 CENPQ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-5 SVIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC12L CDCA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC12L KIF22 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H2BC12L H3-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 SVIL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 H1-4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 SFMBT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17599839 5220076
H3-4 TOP2A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3-4 KIF22 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H3C2 EZH2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17344414 17210787
H1-4 KIF22 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-4 MYBL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
CENPT SNCB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
PLK1 SNCB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19889641
KIF4A KIF4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10747093 10804209
KIF22 KIF4B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15326200 8599929
CRK ATXN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
ATXN1 RPL10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
INCENP AURKB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218018 16239925
RACGAP1 AURKB â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18201571 6166552
AURKB BIRC5 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 19357306 0900833106
CHAF1A CCNA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218806 16826239
CCNB1 CDCA5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
MYBL2 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15510213
CDK1 CDCA5 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 21878504 21987589
NUSAP1 CDCA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12963707
TPX2 CDCA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12389033
RACGAP1 CDK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 18201571 6166552
MYBL2 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15510213
CDK1 TPX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 25688093 29052541
CRK TPX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
CRK KIF22 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PJA1 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 28067271 23688634
IMMT KIF22 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
INCENP PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19228686
NPM1 KIF22 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KIF4A KIF22 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15326200 8599929
PJA1 KIF22 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
RACGAP1 PLK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19468302 1000111
PRC1 PLK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1000110 19468300
RACGAP1 PLK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 1000110 19468300
STAT6 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20006706
FZR1 TPX2 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
INCENP KIF22 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
CDCA5 TPX2 â—¼   CORRELATES + 0.8 0.8 CCLE 31978347
ATAD2 ATAD2B â—¼   CORRELATES + 0.81 0.81 CCLE 31978347
BARD1 AURKB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22350409 19176389
IMA3 IMA4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 26344197
SVIL ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33731348 11792840
KIF22 TBC15 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KIF22 UBP47 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CNPY2 KIF22 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CDCA8 KIF22 â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
CDCA8 INCENP â—¼   CORRELATES + 0.82 0.82 CCLE 31978347
MK14 UBP47 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
MK14 TPX2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
MK14 KIF22 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
KIF22 IMA3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
KIF22 IMA4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
CDK1 BIRC5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11861764 17681274
ESR1 IMMT â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33731348 31527615 19805454
CDCA5 INCENP â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
CHAF1A CHAF1B â—¼   CORRELATES + 0.83 0.83 CCLE 31978347
ESR1 EZH2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31527615 17502350
PLK1 PRC1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19468300 17351640 31586073
AURKB CDCA8 â—¼   CORRELATES + 0.84 0.84 CCLE 31978347
BIRC6 PLK1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26496610 18329369
PRC1 KIF4A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15297875 31586073 23870126
INCENP TPX2 â—¼   CORRELATES + 0.86 0.86 CCLE 31978347
FZR1 PLK1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CDK1 EZH2 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
MIS18A MIS18BP1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
CDCA8 INCENP â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
RACGAP1 ECT2 â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 18201571 6166552
WDR76 HELLS â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 33288900 31353912 25817432 28514442
CENPQ CENPU â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
ZWINT CASC5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 20360068 15824131 24981860 26496610 26186194 21199919 28514442 17981135
ATAD2 ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31527615 25640309 17998543
INCENP BIRC5 â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 5219326 17099693
CDK1 CCNA2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14681455 33961781 33422522 17679094 25852190 26496610 24302728 19483727 12853968 26186194 21308745 8463339 28514442 9053846 23602568 32707033
KIF22 SIAH1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11146551 16713569
CASC5 ZWINT â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
AURKB CDCA8 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
AURKB ZWINT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21775627
H3C2 UHRF1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 22064703 17673620 22348533
ESR1 BARD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17275994
AURKB H1-4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21511733
MYBL2 CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15510213 17242210 19252525
PLK1 CDCA5 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 11509732 15737063 21987589
CDK1 KIF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 29771379
PLK1 CENPQ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 25670858
PRC1 RHOA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 23444367 16431929 23716662
BIRC5 CDCA8 â—¼   PHYSICAL_INTERACTION 909.0 0.9 STRING 36370105
CHAF1A H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 7219095 19498464
H3C2 CHAF1A â—¼   PHYSICAL_INTERACTION ✅ 0.91 0.91 mint 7219095 19498464
H3C2 CHAF1A â—¼   PROXIMITY ✅ 0.91 0.91 mint 25281560
PLK1 CCNB1 â—¼   PHOSPHORYLATION ✅ + 0.91 0.91 Signor 11242082
ECT2 RACGAP1 â—¼   PHYSICAL_INTERACTION 914.0 0.91 STRING 36370105
CHAF1B H3C2 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 24981860
H3C2 CHAF1B â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 7219095 19498464
H3C2 CHAF1B â—¼   PROXIMITY ✅ 0.92 0.92 mint 25281560
CCNA2 CDK1 â—¼   PHYSICAL_INTERACTION 929.0 0.92 STRING 36370105
AURKB BIRC5 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
CDCA8 BIRC5 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 5219326 17099693
CHAF1A CHAF1B â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
KIF4A KIF4B â—¼   CORRELATES + 0.95 0.95 CCLE 31978347
CCNB1 FZR1 â—¼   PHYSICAL_INTERACTION 970.0 0.97 STRING 36370105
AURKB INCENP â—¼   PHOSPHORYLATION ✅ + 0.97 0.97 Signor 12925766
CCNB1 CDK1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
H3-4 RIF1 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 15468306 15574327 23333306 23306437 15723659 23727112
UHRF1 TOP2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10646863 12530060
AURKB H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 11278789 19007248 17938195 10464286 16457588 12234980 12082625 21282660 15249581 10949293 15108802 16185088 14583461 12588998 15681610 17924679 16222246 15684425 12560483 11856369
EZH2 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18022353 15196462
ATAD2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17998543 25640309
BIRC5 AURKB â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
AURKB INCENP â—¼   PHYSICAL_INTERACTION 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
BIRC5 AURKB â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
AURKB INCENP â—¼   SHARES_COMPLEX 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
AURKB INCENP â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 12925766 14722118 14767480 15249581 16571674 17199039 17956729
AURKB KIF20A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 27939310
AURKB CKAP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20458174
AURKB KIF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 15630414 26148251 14972678 14960279 17567953 19632184 15064354
AURKB INCENP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 18773538 20619651 26460953 16565220 21554500 19303298 18477699 33067654 27332895 22024163 15316025 24344188 20068231 19357306 22814604 19951914 15249581 25892238 16571674 27512725 11050385 12925766 18669648 15630414 18767990 18691976 17956729 20562864 21051298 32028528 19369195 19995937 20739936 16239925 32356865 20430883
AURKB BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 39.0 1.0 Omnipath 17145710 23955284 21554500 16291752 18477699 12419797 27332895 19357306 14610074 20807437 17457057 29371939 17099693 11516652 24571573 17681274 21051298 19995937 16769825 20430883
AURKB RACGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15630414 14744859 19007248 17178910 19555392 18201571 17287340 12689593 15108802 18669648
AURKB KIF4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 28992084 31881080 23940115 25512391
BIRC5 INCENP â—¼   PHYSICAL_INTERACTION 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
BIRC5 INCENP â—¼   SHARES_COMPLEX 5.0 1.0 ACSN 12925766 14767480 15249581 16571674 17956729
CDK1 BIRC5 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 11069302 12124778 12792650 14551205 15279786 15917306 17303408 17466630 17660363 18414028 18590585 19016842 19081073 19586613 19652693 7575488
CDK1 BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 56.0 1.0 Omnipath 16565220 24281185 18676872 11149963 12529428 24478433 19287963 18936249 18949405 16170024 20068231 28536639 16189514 33710603 20462440 29371939 18691976 15894279 12517802 11861764 11069302 33211707 28392503 21765467 23433354 18931693 15735703 34034636 25468890 26918045 32373497
PLK1 BIRC5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 20427271 22560880 24091645 24069188 21148584 25169932
CCNA2 CDK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17145710 1833185 10924145 8423786
CDK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23799914 34224728 20117088 16784539 24358021 24508230 19470789 10973963 17283331 20228808 18347064 11242082 12397081 10362260 24582498 15582998 20367638 1833185 12447691 9001210 2570636 24101512 23543736 11331587 12524548 22726437 27626412
PLK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 20404109 16854412 26899266 19364923 25362646 20126263 12524548 26729093 11242082 12447691
CDC14B FZR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19680264 18662541
CDK1 PLK1 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17596790 17660363 18414028 18543256 18590585 18995830 19652693 19686080 7575488 9892021
CDK1 NUSAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22101338
CDK1 KIF22 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12727876 27550518
CDK1 ECT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 21189248 16170345 22172673 22898780 18669648 16247472
CDK1 INCENP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 26460953 20427271 25798441 28314740 29971233 19303298 21149564 26528436 20633640 16378098
CDK1 PRC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 29484112 18691976 22621898 17351640 17438553 17512944 16603632 30992425 20633640 23940115 9885575 16964243 27551054 34158398
CDK1 CKAP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19641375 19369249
CDK1 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 28.0 1.0 Omnipath 25841987 34381492 25691891 27941792 27653691 23549878 25800736 22187039 23241245 25038756 25334066 22964433 27716745 20935635 21131960 29576612 33593912 21123648 23438432 21659531 26552009
CDK1 KIF2C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20368358 29230353
CDK1 NPM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 49.0 1.0 Omnipath 17081983 12058066 27253419 22285574 25908633 20333249 16912078 27553022 19933706 16083285 20068231 27619510 17570479 18669648 7213797 81161106 26536659 11278991 17287340 17924679 15190079 14670079
CDK1 PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19652693 18590585 7575488 17303408 12124778 17764786 17660363 15279786 15917306
CDK1 KIF20B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11470801
PLK1 CENPU â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 17188028 20148280 17081991 19597481 21454580 24722413 25658810 18215321 34094674
CHFR PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 34140642 17442268 16647857
PLK1 ECT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17332740 18669648 16247472
ECT2 RHOA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9789025 32203420 9113980 9641915 15774750 11149925
KIF4A PRC1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23870126 15297875 15625105
PLK1 NPM1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 19651622 17081983 20068231 27619510 15190079 20352051 19413330
PLK1 RACGAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 28692064 17081983 16565220 27453045 19007248 19468300 25486482 19468302 19690332
PLK1 TOP2A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 25328138 8939955 11699638 19098900 18062778 18171681 7499337 7961967 29915179
STAT6 RHOA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19857574 20859068 20006706