Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NEDD8 CUL1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 0806155105 18723677
TP53 BTBD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
BTBD2 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TP53 PRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16227626 9806359
CEBPG PRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16227626 15778982
PRL ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25193864 19524120
PRL STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19262752 10358079
AURKA CDK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1001737 24358021
AURKA TP53 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 14702041 19121998
STAT5A AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22729867 18586824
STAT5A AURKA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18586824
STAT5B BCL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16819511 15711548
TP53 BCL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16249378
BCL6 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15577913
TP53 CDC42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
CDK1 RUNX2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17171635 16407259
CEBPB PRLR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16651265 21670145
CEBPG PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10862621 12524424
CEBPG CSN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 7491114 7629103
CEBPG FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15860545 10531366
MYC CSN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1508191 17512931
STAT3 CSN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9195960 7519723
YY1 CSN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8264581 8114709
SMAD3 CSN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18335503 18024957
STAT5A CSN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15534001
TP53 CSNK2A1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
PTPN1 CSNK2A1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 6732073 9600099
CSNK2A1 RELA â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 5212888 10938077
CSNK2A1 CSNK2B â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
TP53 CSNK2B â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12393879 11239457
CUL5 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
TP53 DDB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11971958
FOS DDIT3 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
STAT6 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8415882 23461825
ESR1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16704985 11279135
EP300 RELA â—¼   ACETYLATION ✅ 2.0 0.8 intact 5214468 11533489
POU2F1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18000219 20215511
ESR1 RAC1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21118977 11060289
ESR1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16144913
NCOA1 ESR1 â—¼   PROXIMITY 2.0 0.8 intact 5222291 17627277
ESR1 PTPN1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 6673088 7539106
TP53 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10766163 16713569
ESR1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 3677090
ESR1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 16144913
STAT5B ESR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11731618
ESR2 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10037443
FOS TP53 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
STAT5A FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9885561 10512880
PPARA FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17360982 18754816
STAT6 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18342537 11922943
FOS SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11854297
FOS RELA â—¼   PROXIMITY 2.0 0.8 intact 18172215 0705181105
RELA FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16189514 10488148
ID4 GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
GRB2 SMAD3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
STAT1 IRF8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19161415
TP53 JUN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11350971 10984493
RELA JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17310108 10646503
JUN RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11604227
STAT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10637230
STAT3 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22943793 15810077
NCOA1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16186500 14551261
PLK1 NEK9 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16079175 21642957
NR0B1 PGR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 12771131
YY1 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12039077 10030686
RELA PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 8626413
STAT3 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22108192
PLK1 TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 7266226 19833129
PPARG POU2F1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12881480
RELA POU2F2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9360945
STAT1 PPARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24242046
RELA PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10542237 16189514
SMAD2 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21836474 21926264
STAT5A PRLR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11145745 10373481
STAT5A PTPN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12237455 6671710
STAT3 PTPN1 â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 15821101 6673264
PTPN1 STAT5A â—¼   DEPHOSPHORYLATION ✅ 2.0 0.8 intact 12237455 6671710
RELA STAT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25040843
RELA STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25040843
SKP2 RUNX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 26778333 26091038
SMAD3 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 11331591 21612856
SMAD2 RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15599395 9812998
TP53 SMAD3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21900401
STAT6 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 28430601 10982806
CUL4A RFWD2 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
COPS7A CRBN â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
CUL4A UBC12 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 28581483 32494016 21987584
CSN5 NCOA1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 15604093 10722692 16713569
UBC12 CUL3 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 28581483 21247897 26286618 28475037
SKP2 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.82 0.82 mint 6540196 18239684
CUL2 CSN4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19295130 21145461
CUL2 CSN7B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 21145461
CUL2 UBC12 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28581483 21145461
MYC CUL4A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 20551172
CSN8 BTBD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CSN7A BTBD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
DET1 CSN5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
APBB3 CSN5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DENR CSN5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KLH10 CSN5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CSN5 FXL14 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 21145461
CSN5 FEM1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31950832 21145461
DCAF4 CSN4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
APBB3 CSN4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KLH10 CSN4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FBX7 CSN4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DET1 CSN4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DENR CSN4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NEDD8 CSN4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16503656 21145461
CSN7A DCAF4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
DET1 CSN7A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SKP2 CSN7A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
APBB3 CSN7A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CRBN CSN7A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24292625 27029275
KLH10 CSN7A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FXL14 CSN7A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LLR1 CSN7A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19295130 26496610
NEDD8 CSN7A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16503656 21145461
DENR CSN7A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FBX7 CSN7A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FBX7 CSN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FBX7 CSN3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FBX7 CSN7B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BTBD1 CSN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DCA11 CSN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DCAF4 CSN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KLH13 CSN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 21145461
FXL14 CSN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DET1 CSN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
APBB3 CSN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KLH10 CSN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CRBN CSN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24292625 27029275
DET1 CSN6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KLH10 CSN6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
APBB3 CSN6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FBXL5 CSN6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EP300 CSN6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16169070 33742100
DENR CSN6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CSN8 APBP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CSN8 FEM1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RFWD2 CSN8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19295130 12466024
CSN8 DCAF4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CSN8 BTBD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KLH13 CSN8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 21145461
FBXL5 APBP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CSN7B APBP2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DCA11 PLK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NEDD8 DCA11 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21145461 18247557
CUL5 DCA11 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31253590 21145461
FBXL5 KLDC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KLDC3 CUL5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 18187417
APBB3 CSN7B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CSN7B BTBD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DCAF4 CSN7B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DENR CSN7B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DET1 CSN7B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CSN7B FEM1B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KLH10 CSN7B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FXL14 CSN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FXL14 CSN3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KLH10 CSN3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KLH10 CUL3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KLH10 CSN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CSN2 COT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 10207062
APBB3 CSN3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
APBB3 CSN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ESR1 AURKA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 21761334
DENR BTBD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MYC CDK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
CRBN CSN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24292625 27029275
DET1 CSN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FBXL5 CSN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DENR CSN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NEDD8 CSN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16503656 21145461
RFWD2 CSN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19295130 12466024
SKP2 CSN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DET1 CSN3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NEDD8 CSN3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16503656 21145461
FBXL5 CSN3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CUL3 CUL5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22709582 21145461
SKP2 CUL5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21119685 21145461
FOS ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17317669 25303530
MYC FHL2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 29467282
RAC1 GRB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 31980649
MYC JUN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 20232342
MYC NEK9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
ESR1 PGR â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
APBP2 CUL2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 18187417 21145461
CUL4A CSN4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16964240 21145461 18606781 17079684 19295130 31973889
CSN2 BTBD2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CSN3 BTBD2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 19295130 26186194
UBC12 CSN5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28581483 28514442 33961781
CSN4 FBX17 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 19295130 26186194
CSN4 CRBN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19295130 24292625 27029275
UBC12 CSN4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28581483 28514442 33961781
DDB2 CSN4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12732143 33961781 26496610 26186194 28514442 19295130 16260596
CSN4 DCA11 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 19295130
CSN4 BTBD1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 19295130
CSN7A DCA11 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 19295130 26496610
CSN7A BTBD1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
DDB2 CSN7A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12732143 33961781 26496610 26186194 28514442 16260596
UBC12 CSN7A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28581483 28514442 33961781
CSN2 FBX7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
FBX17 CSN7B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
FBX17 CSN2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
UBC12 CSN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28581483 28514442 33961781
CUL4B CSN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 34026424 16861906 21145461 22038470 26496610 31973889
KLDC3 CSN6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CUL3 CSN8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 26286618 21145461
DDB2 CSN8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12732143 33961781 26496610 26186194 28514442 16260596
LLR1 CSN8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 19295130
UBC12 BTBD1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28581483 28514442 33961781
UBC12 CSN2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28581483 28514442 33961781
UBC12 CSN7B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28581483 28514442 33961781
CSN2 APBP2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CSN3 APBP2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
LLR1 CSN2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 19295130 26186194
LLR1 CSN3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 19295130 26186194
DCA11 CSN2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 19295130 26186194
CSN7B DCA11 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 27173435
CSN3 DCA11 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 19295130 26186194
KLDC3 NEDD8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 26186194 21145461
KLDC3 CSN2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CUL5 CSN7B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 31253590 21145461
DDB2 CSN7B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CSN3 BTBD1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 19295130 26186194
CSN2 BTBD1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CEBPG JUN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 23661758
CEBPG FOS â—¼   PHYSICAL_INTERACTION 830.0 0.83 STRING 36370105
CSN3 CRBN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19295130 24292625 27029275
DDB2 CSN2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12732143 33961781 26186194 28514442 19295130 16260596
CSN2 DCAF4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CSN2 FEM1B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DDB2 CSN3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12732143 33961781 26496610 19295130 16260596
CSN3 FEM1B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CSN3 DCAF4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
FOS DET1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 35140242 26186194
ESR2 EP300 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 18765668 11500849
SMAD4 JUN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25609649 10220381
ESR1 TP53 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
RELA STAT3 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
NR3C1 STAT3 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
NR3C1 RELA â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
CSN1 CUL2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 11337588 21145461
BTBD1 BTBD2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 28514442 12878161 33961781
CSN5 CUL5 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 30587576 31950832 21145461 11337588 31253590
CSN4 CUL5 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31253590 11337588 21145461
CSN7A CUL5 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 31253590 11337588 21145461
CSN1 CUL5 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31253590 11337588 21145461
CSN6 JUN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25609649 10903862 26237449
CSN8 CUL5 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 30587576 31253590 11337588 21145461
CSN2 JUN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16045761 10903862 25609649
CSN3 CUL5 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19295130 31253590 11337588 21145461
ESR1 NCOA1 â—¼   PROXIMITY ✅ 0.84 0.84 mint 17627277 5222291
SMAD4 SKP2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15314162 16865698
CEBPB ESR1 â—¼   PHYSICAL_INTERACTION 849.0 0.84 STRING 36370105
SMAD3 CEBPB â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12202226 12524424
DET1 CUL4B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 16949367 31973889
CUL4B RFWD2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 31973889 19295130 17041588
CUL4B SIN3A â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25189618 34026424
EP300 FOS â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
SMAD2 ESR1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11555647 20207742
NR0B1 PPARG â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15604093 18381063 19596656 22843091
STAT3 STAT1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 6730629 8662591
CUL4A DCAF4 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
CEBPB EP300 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
DDB2 SKP2 â—¼   KO_DOWN_REGULATES ✅ - -0.86 0.85 PKG 28854368
CUL3 CUL1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26344197 21145461
NCOA1 THA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11435616 15249124 10379889 11117530 9849963 9804773 15140878
CSN2 CUL5 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 32047038 31253590 11337588 21145461
NEDD8 CUL4B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24654937 10597293 18274552 21145461 16503656 23201271 31973889 16620772
SMAD4 EP300 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 18215124 25514493 10887155 22033265 9679056 14612423 9843571
ESR1 STAT3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23874500 11429412
ESR1 STAT1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31527615 25303530
ESR1 FHL2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31527615 15666801
RAC1 STAT3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 11021801 16189514
EP300 RUNX2 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
CDK1 SKP2 â—¼   PHYSICAL_INTERACTION 868.0 0.86 STRING 36370105
CUL4A CUL1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17079684 32235678 21145461
CUL1 CSN7B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 27833851 29103612 21145461
KLDC3 CUL2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 21145461 18187417 26186194 28514442
CSN3 CUL2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 21145461 26186194 28514442 19295130 16036220
CUL2 CSN8 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 27173435 21145461
CUL2 LLR1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19295130 15601820 33961781 21145461
CUL2 CSN7A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19295130 26496610 21145461
CUL4A CSN3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 16964240 21145461 18606781 26186194 17079684 28514442 19295130 31973889 16036220
CUL4A CSN7A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16964240 21145461 26496610 18606781 17079684 19295130 31973889
CUL4A CSN8 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 27173435 16964240 21145461 18606781 17079684 28514442 19295130 31973889
CUL4A CSN7B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 16964240 21145461 18606781 17079684 28514442 19295130 31973889
CUL3 BTBD2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 32296183 17543862 21145461 19995937 19295130
CSN5 FBX7 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 21145461
CSN5 BTBD1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 21145461 26186194 28514442 19295130
CSN5 DCAF4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19615732 28514442 33961781 21145461
CSN5 DCA11 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28446751 31950832 21145461 19615732 19295130
CSN5 CRBN â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24292625 27029275 31950832 21145461
CSN5 FBXL5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 21145461
CUL3 CSN4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 19295130 21145461
CSN7B CSN7A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 22863883
CUL4B CSN7A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 21145461 26496610 19295130 31973889
CUL3 CSN7A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 21145461 27833851 28514442 19295130
CSN6 DCA11 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28446751 21145461 19615732 26186194 28514442 19295130
CSN6 DCAF4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 21145461 19615732 26186194 28514442
CSN6 FXL14 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 21145461
CSN6 UBC12 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28581483 28514442 33961781 21145461
CUL4B CSN8 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 27173435 24981860 21145461 26496610 28514442 31973889
CSN8 DCA11 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 27173435
CSN8 CRBN â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 24292625 27029275
CUL3 CSN7B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 27833851 21145461
CUL4B CSN7B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 21145461 28514442 31973889
COPS7A DDB2 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
CSN2 SIN3A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10207062 15173382
CSN3 CUL3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 21145461 28514442 19295130 16036220
FEM1B CUL5 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 18187417 33961781 21145461
MYC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12776737 16287840 32140074 15616592 16126174 17157259
CSNK2A1 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
DET1 RFWD2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
MYC SKP2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
RFWD2 TP53 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
CUL1 FBXL5 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EP300 STAT1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EP300 STAT3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
ESR1 ESR2 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
AURKA TP53 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CUL4B DCAF4 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
DDIT3 FOS â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
EP300 PPARG â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
SMAD2 TP53 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
CSN1 CUL1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21169563 19141280 29103612 21145461 34237211 11337588 16036220
CSN3 CUL1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19141280 29103612 21145461 19295130 16036220
CSN7A CUL1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29103612 19141280 21145461 12628923 27833851
CUL1 CSN4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19141280 29103612 21145461 19295130 16036220
CUL1 UBC12 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18805092 17914462 27591266 18826954 27348078 19245792 28475037 12565873 21247897 24949976 28581483 21946088
CSN2 CUL2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 26976604 31444342 21145461 32047038 11967155 22013077 26186194 28514442
DET1 CUL4A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 16964240 16949367 14739464 17452440 28514442
CUL4A DCA11 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 27203182 16964240 21145461 32235678 28453520 16949367 17079684 30945288 28514442 19295130 31155351 31973889
CSN5 KLH13 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19615732 21145461
CSN4 CSN7B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 27173435 26344197 27833851 22939629 22863883 32034103 28514442 19295130
KLH13 CSN4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19615732 21145461
NEDD8 CSN1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 27029275 21145461
CSN6 KLH13 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19615732 21145461
KLH13 CSN2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19615732 21145461
DCA11 CUL4B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28446751 34026424 21145461 26496610 16949367 28514442 31155351 31973889
CSN2 CSN7B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 27173435 31444342 26344197 27833851 22939629 26186194 32034103 28514442 22863883
CSN3 CSN7B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 24981860 22939629 27833851 20399188 26186194 32034103 28514442 19295130
CDC42 RAC1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31871319 9427749
CEBPB CEBPG â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20102225 12177065
CUL4B CSN2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 24981860 16861906 21145461 26496610 26186194 28514442 31973889
NR0B1 CSN2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10713076 16713569 16189514
CSN2 CUL3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 26976604 21145461 32047038 16045761 28514442 19295130
DCAF4 CUL4B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28446751 21145461 26496610 32140073 16949367 30945288 28514442 31973889
SKP2 EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18243116 22770219 26593157
EP300 PPARA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18797151 9407140 10336495
NR0B2 ESR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11861507 9773978
FOS SMAD3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9732876 21829441
JUN STAT3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10490649 16713569
MYC PLK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29467282 27773673 30415952 17314511 33494392
NCOA1 NR3C2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
COPS7A CUL4A â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
STAT1 STAT3 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
TP53 TP63 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
EP300 SMAD4 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
EP300 YY1 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
JUN RFWD2 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
NCOA1 STAT6 â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
CUL4B DDB2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
FBX17 CUL1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 29103612 21145461 26186194 18203720 28514442
CUL1 CSN2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26976604 19141280 29103612 21145461 32047038 11967155 16045761 16036220
CUL1 CSN8 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19141280 29103612 21145461 18173839 22959436
CUL1 FXL14 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28514442 29103612 21145461
CSN5 CUL2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21145461 19615732 22013077 22956996 19295130 18850735
CSN6 CUL2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21145461 19615732 26186194 28514442 19295130
CSN1 CUL4A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26976604 21145461 27029275 22414063 18606781 17079684 31973889
CSN5 CUL4A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12732143 26976604 33961781 16964240 21145461 19615732 32047038 27029275 25349427 18606781 23357576 17079684 26186194 22956996 28514442 19295130 18850735 22474075
CSN6 CUL4A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 16964240 21145461 19615732 18606781 26186194 17079684 30945288 28514442 19295130 33179082 31973889 22474075
CUL4A CRBN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 20223979 26990986 24292623 27294876 16964240 21145461 24292625 27142104 27029275 32235678 25860244 32132601 26231201 23983124 28514442 31973889
CUL4A CSN2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26976604 16964240 21145461 32047038 27029275 25349427 18606781 26186194 32493769 28514442 19295130 31973889
CSN5 BTBD2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21145461 19615732 26186194 28514442
CSN5 LLR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19615732 19295130 21145461
CSN5 CUL4B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 34026424 23238014 19615732 21145461 26496610 23357576 26186194 30945288 28514442 19295130 18850735 31973889
CSN5 CUL3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21145461 19615732 32047038 22013077 28514442 19295130 18850735 29897280
CSN5 NEDD8 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24654937 25144743 19615732 21145461 16503656
CSN5 SKP2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19615732 34237211 21145461
CSN5 FBX17 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21145461 19615732 26186194 28514442
THA CSN2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10207062 10877839 16189514
CUL4B CSN4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28225217 24981860 21145461 26496610 24292684 19295130 23238014 31973889
CSN7A CSN4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11285227 19141280 9707402 26344197 22939629 26496610 27833851 11337588 10903862 14647295 22863883 23086934 19295130 17403899
CSN6 FBX7 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19615732 28514442 33961781 21145461
CSN6 FBX17 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21145461 19615732 26186194 28514442
CSN1 CUL3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21145461 27029275 11337588 28514442
RFWD2 CSN6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19295130 33101846 21625211
CSN6 CUL5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21145461 19615732 11337588 31253590 19295130
CSN6 BTBD1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21145461 19615732 26186194 28514442
CSN6 FEM1B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21145461 19615732 26186194 28514442
CSN6 DDB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12732143 33961781 21145461 19615732 26496610 26186194 28514442 19295130 16260596
CSN6 LLR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21145461 19615732 26186194 28514442 19295130
CSN6 CUL3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21145461 19615732 28514442 19295130
CSN6 SKP2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19615732 28514442 33961781 21145461
CSN6 NEDD8 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24654937 25144743 19615732 21145461 16503656
CSN8 CSN7B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 27173435 9707402 26344197 27833851 28514442
CUL3 KLH13 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17543862 33872809 21145461 19995937 33130828 30190310 19295130 31515271
ESR1 COT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9395481 12093745
CUL3 BTBD1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 17543862 32296183 21145461 19995937 25011449 28514442 19295130
SMAD4 CEBPB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12202226 12524424 16959612
DDIT3 CEBPG â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 20211142 23661758 20102225 25416956 16189514 12618752
CSN2 IRF8 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10991940 21903422
CSN3 CUL4B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 24981860 21145461 26496610 22863883 26186194 28514442 19295130 23238014 31973889 16036220
JUN DDIT3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23661758 10523647
EP300 STAT6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23461825 17237818 10454341
JUN ESR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17317669 16713569 23747343 11477071
NCOA1 ESR2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11500849 10809226 11014206 19126643 15604093 10731636 11376110 14715875 12554772
RUNX2 FOS â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11274169 11641401
NCOA1 FOS â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18511550 10847592 9642216
NCOA1 JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10567404 10847592 9642216 16713569
SMAD2 JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11371641 10220381 25609649 20195357
RUNX2 JUN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11274169 11641401
NFYC MYC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10446203 11282029
NCOA1 STAT3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11773079 17471507 16713569
NR0B2 PPARG â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16189514 19596656 11696534
SMAD3 RUNX2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10962029 10531362 21986102
NCOA1 PGR â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
CUL4A NEDD8 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
SMAD2 SMAD3 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
CSN6 CUL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19141280 29103612 21145461 19615732 34237211 11337588 19295130 22474075
FBX7 CUL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15145941 33961781 29103612 27503909 21145461 26496610 27497298 10531035 16278047 34060591 28514442 18495667
CSN5 CUL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34237211 21903097 26265931 29103612 21249194 27774986 25144743 19615732 22767593 24973710 22959436 22956996 18850735 31950832 19141280 21145461 22013077 29863914 22474075 16036220
MYC CUL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10970882 12835716
MYC CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16376880 16915296
RFWD2 CUL4A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24298020 17041588 21145461 14739464 17079684 25117710 32041890 19295130
BTBD2 CSN6 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21145461 19615732 26186194 16169070 28514442
PGR PRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 7113584 8015553 10499541
CSN7A CSN5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 22939629 26496610 17429597 22863883 19656241 26344197 12628923 20399188 19295130 19615732 27833851 28514442 18850735 11285227 31950832 21145461 11337588 10903862 26186194 17403899
CSN5 SMAD4 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 27060206 11818334 17583730 16713569 14993265 24078030 16189514
CSN5 CSN7B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 16624822 27173435 31444342 31950832 21145461 19615732 22939629 27833851 20399188 22863883 26186194 32034103 28514442 19295130 18850735
CSN5 JUN â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20093369 10766246 25609649 10903862 16713569 8837781
CSN5 DDB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12732143 33961781 21145461 19615732 32985517 26496610 16260596 26186194 17079684 28514442 18850735
CSN7A CSN3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25043011 11285227 26344197 22939629 26496610 27833851 11337588 24421388 20399188 10903862 22863883 26186194 28514442 19295130 16036220
CSN8 CSN7A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25043011 11285227 9707402 26344197 27833851 26496610 11337588 10903862 22863883 23213463 28514442 19295130 17403899
CSN6 CSN7A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25043011 19141280 26344197 21145461 19615732 27833851 26496610 10903862 22863883 26186194 23086934 28514442 19295130 17403899
CSN7A CSN1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14681455 25043011 11285227 33961781 26344197 22939629 26496610 27833851 11337588 20399188 27029275 10903862 22863883
CSN7A CSN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25043011 11285227 26344197 12628923 22939629 26496610 27833851 11337588 10903862 22863883 26186194 28514442 19295130
CSN1 CSN7B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14681455 33961781 22939629 27833851 22414063 20399188 32034103 28514442
CSN6 CSN7B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 27173435 26344197 21145461 19615732 27833851 22863883 26186194 32034103 28514442 19295130
CSN6 CUL4B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21145461 19615732 26496610 22863883 26186194 28514442 19295130 31973889
CSN6 CRBN â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21145461 19615732 24292625 27029275 19295130
NIF3L CSN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12522100 16713569 16189514
ARRB2 ARRB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17353931 24069330 28514442 17620599
ESR1 AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21761347 21761334 18497064
SIN3A BCL6 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9765306 16147992 9753732
STAT1 BCL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19122651 15596057
TP53 BCL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23852341 19427386
EP300 BCL6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17828269 12402037
CDC42 GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDK1 NEK9 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16079175 12101123 21642957
EP300 CEBPB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9343424 14630807 12471036 28428115
CEBPB CSN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11726661 14976147 11158330
CEBPB RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17579210 21302301 21612856
CEBPB MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21098707 20581311 16585579
SMAD3 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12202226 12524424
CEBPB RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15713650 11668178
CEBPG DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15781252 12082616 12069855
FBXL5 CSNK2B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
NEDD8 CUL5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18805092 24654937 33961781 18274552 10597293 21119685 21145461 23201271 24076655 18247557 28522566 22405651 31253590 28514442 20847044
FOS DDIT3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 32814053 23661758 10523647 26264872 20102225 16189514 29997244 31467278
JUN DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19299913 22622069 12069855
YY1 EP300 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22951020
EP300 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20851880 22298955 12697832
NCOA1 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9259327 10409727 23874500 11014206 15604093 12554772 16282588 9427757 11113179 18451880 9121466 10598586 16713569 11165056 14715875 11376110 9774463 10760302 20608937 9192892 11003650 26487511 11867769 10454579 12574227 17363140 9773983 10731636 11358671 11250900 11682626 23975195 17627277 16606617 12630920 12714702 9192902 12738788 16957778 15140878
ESR2 ESR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19022902 19746436 10706629 12630920 9473491 21182203 29509190 17991765
RUNX2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17350616
STAT5B ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11731618 11682625
STAT3 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21546410
ESR1 PRLR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16705189 16651265 18414489
NR0B1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 11053406
STAT3 ESR2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23295773 21546410
ESR2 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20155458 10037443
ESR2 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20034404
NR0B1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 11053406
PLK1 FBXL5 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
TP53 FHL2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18615633 11062252 22796152
PPARG FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10678274 23657115 18059282
NR0B2 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19509248 12571228 9452499
TP53 ID4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19500415 19783986 21293053
STAT1 IRF8 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10092656 16918696 19074829
RFWD2 JUN â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 15994960 27534417 12615916 25609649 14739464 25117710 28514442 31155351
SMAD3 JUN â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10903323 10220381 11306568 21829441 9732876
SMAD4 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12374795 10022869
SMAD3 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12374795 10022869
JUN NR0B2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15292277 12842887 19322021
JUN PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 14684847 12446585
JUN NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16713569 7823959 8733011
SMAD2 MYC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28205554 11804592 28628118
YY1 MYC â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 18490439 19219071 2191300
STAT5A MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17927978 12048235 12967477
MYC STAT6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
RELA MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12027803 16713569
PPARG NCOA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10347167 15604093 15026545 30813326 11877444 19596656 17704298 30595551 9041124 9121466 9744270 23178929 10339548 16713569 15888456 17513608 22070604 17449869 10731636 20717101 10848596 17468099 11027271 17312272 11500849 23975195 17011503 16373399 10944516
NR0B2 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24038081 16803864 11696534
NR0B2 PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 11369442
TP63 NR3C1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17521434
NR3C1 RELA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 12734399 9261164 9442377
TP53 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
PPARG NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15531761
NR3C1 PPARG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 15531761
NR3C1 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16189514 8878484 9528750
NR3C1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 11080152 16713569
RELA PPARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20054868 10542237
TP63 PPARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19458633
PPARG TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16887883 14960510
STAT1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16481475
STAT1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 24655378 14602726
STAT3 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16107692 23874455 20043094
STAT5B STAT5A â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15043997 17997837 14532269
STAT5A STAT5B â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21542777 15043997 17997837
TP63 STAT6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17521434
CUL4A DET1 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
CSN2 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
CRBN CUL4A â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
EP300 JUN â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
CSN3 UBQLN2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
EP300 TP53 â—¼   POLYUBIQUITINATION ✅ - 0.91 0.91 Signor 12690203
EP300 RELA â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
CUL4A DDB2 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
EP300 ESR1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
PRL PRLR â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
CUL3 NEDD8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
EP300 SMAD3 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
CSN4 CSN3 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 33961781 25043011 11285227 9707402 26344197 24981860 22939629 11337588 20399188 14647295 22863883 26186194 32034103 28514442 19295130 16036220
NEDD8 CUL2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 23401859 24654937 18274552 10597293 10318914 21145461 31444342 18826954 16503656 23201271 18247557 19617556 18173839 17132228 10585493 16620772
CSN4 CSN5 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 32034103 22863883 26344197 20399188 19295130 16624822 19615732 28514442 18850735 11285227 27173435 31950832 9707402 21145461 24725084 11337588 14647295 26186194 23086934
CSN8 CSN4 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 25043011 11285227 27173435 9707402 26344197 24981860 22939629 11337588 14647295 22863883 23086934 28514442 19295130
NEDD8 CUL1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21765416 16177058 18723677 18627766 17438373 32726803 24654937 11027288 18274552 10772955 16503656 24076655 18247557 22405651 17318178 10713156 19713960 10318914 21102408 23267066 23201271 22959436 17206147 16620772 18805092 10597293 21119685 21145461 18826954 19245792 19617556 12565873 18264111 24949976 22474075
CSN8 CSN5 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 25043011 11285227 27173435 31950832 9707402 21145461 19615732 11337588 20399188 26186194 28514442 19295130 18850735 23636414
CSN1 CSN5 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 32034103 14681455 26344197 27029275 24421388 20399188 16624822 19615732 22414063 28514442 18850735 25043011 11285227 31950832 23926101 19444310 21145461 11337588 26186194
CSN3 CSN5 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 32034103 22863883 26344197 24421388 20399188 19295130 16624822 19615732 28514442 18850735 23636414 25043011 11285227 31950832 21145461 11337588 26186194 16036220
CSN5 CSN2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 22939629 32034103 22863883 23408908 26344197 20399188 19295130 26976604 16624822 19615732 16045761 28514442 18850735 25043011 11285227 27173435 31950832 21145461 11337588 10903862 26186194
CSN1 CSN4 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 14681455 25043011 33961781 11114242 26344197 22939629 27029275 22414063 20399188 22863883 32034103 19295130
CSN4 CSN2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 25043011 11285227 27173435 31444342 9707402 26344197 24981860 32034103 22939629 11337588 10903862 14647295 22863883 26186194 16045761 28514442 19295130
CSN8 CSN1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 14681455 25043011 11285227 27173435 19141280 9707402 26344197 33961781 12324474 27029275 22414063 11337588 24421388 20399188 32034103 28514442 22863883
CSN6 CSN1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 14681455 25043011 11285227 33961781 19141280 21145461 19615732 27029275 22414063 11337588 24421388 20399188 26186194 32034103 28514442
CSN8 CSN6 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 25043011 11285227 27173435 9707402 26344197 21145461 19615732 22939629 11337588 22863883 26186194 32034103 28514442 19295130
CSN6 CSN2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 25043011 11285227 27173435 32034103 26344197 21145461 19615732 22939629 11337588 10903862 22863883 26186194 16045761 28514442 19295130
CSN6 CSN3 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 25043011 11285227 26344197 21145461 19615732 22939629 11337588 20399188 24421388 22863883 26186194 32034103 28514442 19295130 16036220
CSN8 CSN3 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 24981860 22939629 32034103 22863883 26344197 20399188 19295130 32296183 28514442 25043011 11285227 27173435 19141280 9707402 31444342 11337588 26186194 16036220
CSN8 CSN2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 25043011 11285227 27173435 9707402 26344197 24981860 11967155 22939629 11337588 10903862 26186194 16045761 28514442 22863883
UBC12 NEDD8 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21765416 33961781 16735510 28581483 24654937 18274552 16503656 10828074 18652489 23936405 19713960 17353931 23267066 23201271 9694792 28514442 25416956 30804002 16620772 21145461 19245792 18264111 10207026
CSN3 CSN2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 24981860 22939629 32034103 22863883 26456823 26344197 24421388 20399188 19295130 16045761 28514442 25043011 11285227 31444342 11967155 11337588 10903862 26186194 16036220
CUL2 NEDD8 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
ESR2 NCOA1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
NCOA1 PPARA â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
NCOA1 NR3C1 â—¼   PHYSICAL_INTERACTION 978.0 0.97 STRING 36370105
CUL5 NEDD8 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
CSNK2B CSNK2A1 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 36833176
TP53 EP300 â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16611888 6599495
ESR1 NCOA1 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
NCOA1 PPARG â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
FOS JUN â—¼   PHYSICAL_INTERACTION 985.0 0.98 STRING 36370105
TP53 FHL2 â—¼   KO_DOWN_REGULATES ✅ - -0.99 0.98 PKG 28854368
CSN6 CSN5 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 22939629 32034103 22863883 26344197 20399188 19295130 12220626 25144743 19615732 28514442 18850735 25043011 11285227 27173435 19141280 31950832 21145461 11337588 26186194 21625211
CSN6 CSN4 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 22939629 32034103 22863883 26344197 19295130 32296183 19615732 28514442 25043011 11285227 27173435 19141280 9707402 31444342 21145461 11337588 14647295 26186194 23086934
CSN1 CSN2 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 22939629 32034103 22863883 14681455 26344197 27029275 24421388 20399188 11114242 32296183 22414063 16045761 28514442 25043011 11285227 19141280 31444342 11337588 10903862 26186194
CSN1 CSN3 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 22939629 32034103 22863883 14681455 26344197 27029275 24421388 20399188 11114242 22414063 28514442 25043011 11285227 19141280 31444342 11337588 10903862 26186194 16036220
EP300 TP53 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CSNK2A1 CSNK2B â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
SMAD2 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
SMAD3 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
RELA CUL1 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 9990852 10514433 9859996 9990853 7628694
CUL1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 SKP2 â—¼   PHYSICAL_INTERACTION 19.0 1.0 ACSN 11516665 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15668399 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
CUL1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 SKP2 â—¼   SHARES_COMPLEX 19.0 1.0 ACSN 11516665 11900249 12648680 12820959 15071497 15147722 15340381 15459660 15668399 15688063 15703371 16697054 17884153 18931676 19270156 19622404 19686080 19809470 19847258
CUL1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11359933
NEDD8 CUL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16620772 15688063 11696557 21145461
NEDD8 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9694792 18805092 21145461 19250909 19231300
STAT5B PRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 19014541 9528750 11721695 10373481 11682625
CEBPB PRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10455153 15479564 10649437 24248464 16227626
STAT5A PRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 9341115 7479881 15778982 9773981 19036881 12060651 12819296 16847321 10406460 15637146 23313770 9806359 20124477 12459499 7744007 8018556 23729680 9545277 21964595 10373481 11682625
ESR1 PRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 3481434 9259323 7649480 18022314 2082192 10830306
ESR2 PRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18022314 10342855
PRL PRLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 10585417 23048206 2558309 23192981 22325776 23331499 15082796 18988627 9626554 7984244 18253483 10966654 21889455 18467331 11356126 20053995 16546209 29145629 9175708 24243840
CSNK2A1 ARRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11877451 32863206
MYC AURKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20890087 20519624 14744757 20682043
AURKA PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 63.0 1.0 Omnipath 18566290 23618492 27721411 24338364 15713655 28126323 34260926 19364923 33805672 33771996 32284347 27504491 33898950 10980711 26206521 21474997 32060423 27662907 28994651 33963314 18615013 23695676 34197606 18669648 25925375 26114094 19228686 28591578 22281053 18691976 20603326 15611664 27068477 27908669 26919439 26012549 18477460 34140642 25660017 27899378 19369195 21454580 25871386 24349352 12207013 20869364 11854496 20633640 28351953 24667170 25042804
AURKA TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 50.0 1.0 Omnipath 24173284 22864622 25217103 24089029 16713569 19413330 25848977 17999753 23565200 25333414 23201157 16552184 10884347 1956339 26186194 29455673 15469940 15749021 18974145 21502403 17287340 28043820 22396649 92065884 12198151 27933271 22852086 12064478 30266789 25398437 17259342 22350019 25634113 14702041
STAT5A BCL6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 16819511 15711548 20498019 20124477 23716595
CDK1 PLK1 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17596790 17660363 18414028 18543256 18590585 18995830 19652693 19686080 7575488 9892021
TP63 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11593387 19861536
TP53 CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 10825186 11593387 12874009 19472317 10514438 11313928 16807237 8270002 17942917 9275177 20395210 11032828 19861536 12889596 19067706
MYC CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18802399 2237430 8065306 11085504
CDK1 CSNK2A1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 7592773 30392930 18691976 19387552 20068231 96029687 16371510 1400350 19941816
CDK1 CSNK2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 16335537 1939094 19007248 17081983 25788269 18691976 20230923 20068231 19387552 17570479 12551973 12396231 19581576 7578274 18669648
CDK1 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16407259
CDK1 PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19652693 18590585 7575488 17303408 12124778 17764786 17660363 15279786 15917306
CDK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 24173284 12767922 1584757 20661218 26029996 2141171 9467949 17570479 20808790 7862459 11327730 11078726 27726420 8357826 16713569 2156209
STAT3 CEBPB â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
ESR1 CEBPB â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19652226 18414489
CEBPB FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15860545 18180320 21292824 12773552 10531366
CEBPB DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8051100 16757577 10085237 8662954
CEBPB PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 22473998 23934183 7557387 12524424 16431920 22610404 15110775 18694725 17242167 16054042 15158467 9950217 10862621 20829347
CEBPB TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 19135161 23564453 19075931 24333671
NR3C1 CEBPB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 25202013 9817600 9428795 11279134
CEBPB STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11134330 18266962
STAT1 CSN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9231797 8830676 9195960 10358045
POU2F1 CSN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15798204 23313770 19266165 12151092 16965262 14729276
PGR CSN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 16973758 21527503 10418993 10732325
STAT5A CSN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 10993888 9341115 8274437 8830676 12746331 19490989 9973262 12060651 18583090 11751614 16973758 10471471 1491685 10418993 15746097 10358045 11604235 18024957 23313770 9252424 12596040 15534001 9806359 9231797 12954634 11167825 11287629 12459499 10732325 7519723 9817603 14646587 8018556 12082616 10834938 12605675 9657743 12732616 8264581 8943229 20980837 16832345 16965262 9343435 11158330 7514531
STAT5B CSN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9341115 10830280 10358045 9231797 18583090 8943229
NR3C1 CSN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 10418993 12954634 23313770 9252424 9973262 9343435 16965262 11158330 11287629 16973758
CSNK2A1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 34049972 15016307 10938077 27630163
CSNK2A1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22184066 23226345
CSNK2A1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 23443559 15358769 9315650 19413330 11285227 11551930 11883897 22975381 11709713 16083285 1088347 33745968 16552184 10884347 10747897 10673501 7936649 12628923 25241761 21127074 16964247 24725084 10606744 10348343 10951572
CSNK2A1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 25609649 1846781 11948398 15378002 12531896 19413330 8654373 15302935 11075956 12628923 11896587 1516134 8464713 11971971 1651323 8137421 9685505 91332050
CSNK2A1 DDIT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 12876286 27650555
CSNK2A1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 11139588 26703694 9337862 20043841 11432835 11507039 9528769 7838153
CSNK2B TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10606744 11709713 10214938 10951572 16713569 11551930 10747897 10673501 11883897
TP53 DDB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 12771027 22336944 15856024 12509284 12170778 16357511 12967652 15927209 11971958
MYC DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 15021909 18483244
STAT1 EP300 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 10918613 11134049 11830590 12193701 12223527 12796776 12811837 12967644 14607900 14764699 15265520 15814715 17016554 17513775 17559085 17689680 18272812 19833085 21263073 21930765 25960930 8683106
EP300 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 9843571 19419955 22033265 9679056 21269274
EP300 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9843571 11134049 12743039 15133024 15824515 15623506 16876108 21567395 16109717 17074756 20564330 10497242 15588252 17469184 15345715 11058129 10575014 16862174
EP300 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18782771 15509516 8756628 10205054 7530500 15653507 15735682 19506034 16285960 16713569 11322950 7499365 15649887 9590694
EP300 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 19608861 25400040 11567019 12419806 17617622 11533489 20333651 12456660 15152190 16846590 9096323 20064247 16382138 16713569 15171256 16135789
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15965232
EP300 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21988832 14726487 15509516 9989503 9773981 26504087
EP300 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 21988832 23331499 9169454 12237408 10199400 11264182 7878020 8047140 12958365 19171760 11371641 16027720 17074756 17469772 21269274 15623506
EP300 STAT6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11509556 15145939 10454341
EP300 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11486036 7758944 18542060 9199306 17510411
EP300 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 137.0 1.0 Omnipath 11907332 25545885 21187340 10706102 16438982 10490106 19339993 15542844 23010591 11433299 19608861 17438265 17906639 16024799 9194564 20234175 23402884 12162806 26229107 16959611 15186775 9744860 11070080 17977830 17189186 22266186 20228809 15664194 19805293 25753752 11804596 26625199 27818144 10648616 16928824 9288740 10942770 12724314 23148227 23728348 15965232 19218448 16678111 16782091 20094059 14612423 24821727 10518217 16713569 9891054 25288747 17452980 14759370 19788416 25156994 18931695 22074660 23880760 15337767 15509808 26302407 22731250 18391200 16543236 19234109 21471221 23307557 25867071 12690203 15558054 18612383 23870121 18243116 19217391 22013068 16537920 16611888 18485870 9194565 12660246 9809062 23796514 11359905 12501250 15295102 19407812 25651062 23329847 16135789
STAT5A ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11731618 22201800 11682624 11682625
ESR2 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 14754635 24284820 15207704 18784357 11566442 12630920 22820289 19001520 18511514 14676837 19207817 22622808 21763263 18339713 15087130
ESR1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11477071 17963131 10037443 16679312
ESR1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 22396492 21835891 15073177 18193094 11517191 21505052 22892083 8707895 19569049 14722073 18414489
ESR1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 20080630 16115928 22787161 12750288 20696891 17681750 17699779
ESR1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8114761 9528985 18414489 10037443 21813366 11726205
ESR1 PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 12829318 12554765 12446585 11000528 15019994 8043503 23027806 9058379 9717846 18414489 12706304 10835496 16293641 18784357 12761896 8145766 22543272 15743834 8530508 10894148
SMAD3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 11555647 23331499
JUN ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
PGR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 22396492 16168121 12612073 11000528 18988627 26153859
NCOA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 18451880 9192892 16957778 11014206 16713569 17627277 23975195 15140878 15604093 12738788 17363140 11003650 10454579 16606617 26487511 11165056 10760302 10731636 12630920 14715875 9773983 9427757 9121466 20608937 12714702 9259327 9192902 11358671 10598586 12574227 11113179 12554772 11682626 9774463
NR0B2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 23331499 21071413 9773978 18988627 11861507
ESR1 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11477071 17317669 16713569
ESR1 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 12630920 9473491 19746436 21182203 10706629 10022879
ESR2 PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 16293641 12761896 11014241 19001520 9717846
NR0B2 ESR2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 10648597 9773978 16189514
JUN FOS â—¼   PHYSICAL_INTERACTION 21.0 1.0 ACSN 10606235 11274345 11274400 14673140 15067049 16393692 16394015 17439715 18222063 18754863 19667062 19846528 21385848 21790308 22381618 22634314 22723415 23430059 26587781 8545107 9064320
FOS GRB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12738796 15067049 16393692 16394015 18039929 19667062 21385848 22634314 23430059 9064320
STAT1 FOS â—¼   UP_REGULATES ✅ + 20.0 1.0 ACSN 11134049 11830590 12193701 12223527 12796776 12811837 12967644 14607900 14764699 15814715 17016554 17513775 17559085 17689680 18272812 19833085 21263073 21930765 25960930 8683106
STAT3 FOS â—¼   UP_REGULATES ✅ + 38.0 1.0 ACSN 10347215 11528470 12223527 13130303 14607900 14670306 15218058 15356132 15573129 15810077 16418395 16716598 16831886 17403902 18297062 18776941 18832382 19380816 19412634 20093776 20237412 20406969 20581311 21317430 21840487 21883379 22006115 22943793 22945800 23124025 23454751 23953057 24857661 27216177 28186502 7543512 7768934 9278421
JUN FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 2513130 14561487 8617996 8934539 19255142 9217081 12760745 2498806 10521486 8597411 10858536 12392213 9819441 1380150 23562910 1944274 9867253 9571041 1900040 2511006 14684847 15467742 12231642 11950097
STAT3 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 17204573 14737107 12640143 12600988 11685114 8071311 15040450 16293640
TP53 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 8604347 17174366 8668332 1946467 10082525 10214938 1508692 8649776 10529369 12173040
NR3C1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16850320 9804760 1314076 8036015 8890955 8733011
STAT1 FOS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 8874187 7510676 8830676 12600988 7507205 8770944 17558387
FOS PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16293641 14684847 12446585
FOS MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11939505 2463066 1696944 8276360 9950153 2139817 2498162 21607323 20410304 8490168 7654239
SMAD4 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 9732876 10942775
NCOA1 FOS â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18511550 10847592 9642216
FOS JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 20498278 16714286 21675959 25609649 23602568 9872330 20102225 8380166 18848838 18535250 2516828 8397339 15867431 18172215 9346889 10779323 9732876 16928824 26496610 15994313 22719067 24029232 16511568 20195357 11053448 20936779 26186194 18619508 20511396 16008525 10488148 21199371 8617242 17440114 16055710 15319445 11090181 9160889 23661758 1631061 15718494 11431474 31515488 8440710 7816143 20410304 34671206
STAT5B GRB2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16627759 22411868 11090077 26515730 20111072 15498859 10698507 12468433 12796379 30552988 23103841 31066629 15003515 17356133
STAT5A GRB2 â—¼   PHYSICAL_INTERACTION 14.0 1.0 Reactome 16627759 22411868 11090077 26515730 20111072 15498859 10698507 12468433 12796379 30552988 23103841 31066629 15003515 17356133
GRB2 RAC1 â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
GRB2 RAC1 â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10982827 11274345 11447289 11756498 11777939 12040186 12175651 12640133 12738796 14585353 15567848 15574420 15863030 16102570 16582911 16887996 17496910 17673906 18000759 18855897 19151919 19449109 19568798 21614932 24027568 26552706 27331412 7510700 8551221
JUN GRB2 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11274345 12738796 17439715 18039929 26587781 8545107
IRF8 MYC â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10734131 11672593 11875494 11964313 12032143 12417340 12811837 16243976 16413922 16597464 17404308 17485448 22461508 23390297 24091328
STAT3 IRF8 â—¼   DOWN_REGULATES ✅ - 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
JUN MYC â—¼   ENZYMATIC_REACTION ✅ 40.0 1.0 ACSN 11274345 11929833 11955436 11967263 12051714 15001769 15576399 15768032 15806138 16007074 16039586 16169192 16510874 17050667 17143292 17291450 17439715 17936032 18347071 18627596 19619488 19623618 20006983 20122174 20530697 20705860 20920541 21285352 21767405 22290435 22705350 22761862 23306204 23343194 24023259 25730849 26587781 7542250 8545107 8666229
PPARA JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 10542237 17360982 18754816 15838301
NR3C1 JUN â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 20499359 8639160 2169353 9731701
JUN MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 21835891 8276360 1774959 2498162 21607323 20410304 14523011 18037408
JUN TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 22859294 17321721 20697347 10348347 12963547 10072388 22353755 18604200
SMAD3 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 9732876 10220381 11306568 21829441 10903323
RUNX2 JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11641401 11274169
RELA JUN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18174238 9468519 16713569 10488148
JUN SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10220381 9312063 9732876
JUN MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 29.0 1.0 Omnipath 15806138 16510874 22290435 18627596 19623618 11929833 23343194 15768032 22761862 17050667 16039586 20122174 17291450 20920541 17143292 20006983 17439715 15576399 21767405 23306204 8545107 22705350 18347071 16007074 16169192 21285352 20530697 19619488 11274345
STAT3 MYC â—¼   ENZYMATIC_REACTION ✅ 33.0 1.0 ACSN 10347215 11875494 12193690 12223527 12907458 14607900 14670306 15218058 15356132 15465827 15573129 16418395 17404308 18776941 19380816 20093776 20237412 20406969 20435894 20580461 20581311 21372296 21765015 21840487 22461508 23124025 23390297 23454751 23953057 24857661 27216177 28186502 7543512
PLK1 MYC â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11073952 17596790 18931676 19270156 19622404 19686080 8127874
MYC STAT6 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
MYC PPARG â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 10432118 11274345 11283614 11875494 16327802 17558397 17873522 20027199 20237412 20551172 20581311 20713526 21093321 21372296 21406394 21765015 2191300 22067385 22461508 23124025 23390297 25002027
PGR MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 8701093 9408078 22396492 9305935 22892083 10651641
YY1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 9797456 16314465 10528225 8266081 19279113 17287852 10713181 18490439 17434929 16878156 18542060
STAT3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 19289167 17204573 18184402 22317895 20067773 15184887 15469392 10464281 9325164 20654581 21573184 17959148 22349830 9874564 20581311 19259613
SMAD4 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 11689553 17132729
PPARG MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11973610 17462534 16405739 19075513
SMAD3 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 15930298 20516082 14993291 17132729 16205635 25238097 11689553 17114344
RELA MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 19469019 21790895 19766095 17018379 8289784 18566231
MYC SKP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 24259667 12963825 12769844 23792459 21245140 24177224 23277542
MYC TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 10962037 10656696 8494784 10348347 19882681 16557594 19086036 15780936 14519204 16112647 11781835 7969121 11789587 9839551
SKP2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17145710 24259667 12963825 12769844 17157259 23277542 20852628 16376880 35260179 26038816
YY1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8266081 15805285 18490439 19219071 2191300
PLK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18931676 19270156 25915540 23887393 19622404 19686080
MYC SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
MYC NFYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11282029 10446203
MYC SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 23331499 11804592
NCOA1 PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 11698662 10731636 9626662 12163133 21775429 15888456 9407140
NCOA1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11773079 16713569 15313931
NCOA1 PGR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 12529333 7481822 10757795 19706513 21273440 16352595 16728408 10722692
NR3C1 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 24811171 27777311 10649448 8754811 11279134
RELA NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 23871663 10995388 7659084 8290595 16713569
NR3C2 NR3C1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16131566 23331499 11326543 11154266
NR3C1 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 12902338 16189514 10518526
NR3C1 NR3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16131566 23331499 11326543 11154266
NR3C1 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 23871663 10995388 7659084 8290595 16713569
TP53 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17172872 17981789 15024021 22405092 20962589 24076372 23948487 15016801 22184120 19713933 16369493 23474762
PLK1 YY1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21253604 23226345 22248053
PLK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22653443 19833129 16753148 23948487
PPARA PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12941763 16226723 20706641 17261671 18769491
PPARG STAT6 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 10432118 10485906 12223527 12244147 14610620 15634881 17681149 21093321 23124025 24204259
PPARG STAT6 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 10432118 10485906 12223527 12244147 14610620 15634881 17681149 21093321 23124025 24204259
SMAD3 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21836474 21926264 12457461 12524424
SMAD4 PPARG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21836474 21926264 16580992 12524424
PPARG RUNX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12878983 18715135 20589837 12704187
PTPN1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15821101 23331499 11970898
PTPN1 STAT5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 10993888 12237455
PTPN1 STAT5B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 10993888 12237455
RAC1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 26430964 16189514 11021801
RELA TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18269916 10348347 11032029 8051093 20061391 15155458 21332394 9890939 21887328
STAT3 RELA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19345327 12057007 23335796 16713569 18448488
SMAD3 RUNX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 21986102 10962029 15084595 11331591 10531362
SMAD3 SMAD2 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
SMAD4 SMAD2 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11399519 11792802 11875494 12193690 12545156 12702545 12809600 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 17055429 17260466 17550342 17689680 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23390297 23784029 23869868 6357187 8515656 8871614 9312026 9389648 9618481 9670020
SMAD2 SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16052471 11376804 11456453 9812998
SMAD2 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 110.0 1.0 Omnipath 15613484 17145710 25609649 15817471 20211142 21532621 24584437 18729074 23788427 12419246 16916642 9288972 9892009 21454478 17510063 10531362 15231748 11027280 12167862 21988832 9389648 23331499 12543979 18568018 21071413 19135894 18511908 15467747 12808092 11927552 25514493 15350224 18988627 12732634 10878024 9111321 9311995 9346908 10199400 11264182 12957874 11114293 15761153 11274206 12621041 17272273 24157709 26555259 12374795 22442258 10781087 15922743 11102446 17591701 18783722 16751102 19139564 19917253 9346966 21297662 17283070 12794086
SMAD2 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 26186194 12543979 9111321 15084259 9311995 25878769 18729074 12700238
SMAD4 SMAD3 â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD4 SMAD3 â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013125 11013220 11074002 11114293 11224571 11279127 11283613 11283614 11376132 11399519 11792802 11875494 12193690 12545156 12702545 12809600 14976548 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 16831886 17018611 17055429 17260466 17550342 17563753 17689680 17705132 18353785 18768831 18832382 19208835 19597490 19815509 19901969 20027199 20713526 20731704 21041997 21042762 21098712 21252118 21317430 21577210 21614932 2191300 22331441 22514743 22652804 23140366 23338822 23390297 23784029 23869868 25374926 6357187 8515656 8871614 8893010 9312026 9389648 9618481 9670020
SMAD3 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 104.0 1.0 Omnipath 25609649 9843571 15084259 20211142 21532621 24584437 18729074 23788427 12419246 18923419 9892009 19768112 10531362 15231748 9679060 12167862 21988832 12150994 23331499 12543979 18568018 21071413 19135894 15467747 25502805 9732876 11927552 16189514 12917407 25514493 15350224 10995777 18988627 10092624 12732634 25910212 10878024 9111321 20564330 27107012 9311995 12957874 20142324 11114293 32296183 15588252 15761153 24157709 26555259 29892012 17469184 22442258 16714330 21597466 15922743 22045334 17591701 24382352 22310290 19139564 19917253 29997244 31515488 28115363 10942775 21297662 17283070 12794086
STAT1 STAT5A â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23073628 15790786 11369651 15007386 12481435 15526160 28403213 10358045 28192400 17546049 9355737
STAT1 STAT5B â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23073628 15790786 11369651 15007386 12481435 15526160 28403213 10358045 28192400 17546049 9355737
STAT1 STAT3 â—¼   DOWN_REGULATES ✅ - 46.0 1.0 ACSN 10485906 10754326 10820262 10952726 11134049 11399519 11830590 11875494 11964313 12193701 12223527 12433365 12796776 12811837 12907458 12967644 14607900 14607933 14660645 14764699 15465827 15644117 15699106 15814715 16127449 16878026 17016554 17260466 17404308 17485448 17513775 17559085 17689680 18272812 18345002 19833085 19879327 21097505 21263073 21930765 23390297 25960930 6357187 7594497 8683106 8871614
STAT1 STAT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19122651 17558387 22693070
STAT3 STAT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 25609649 8662591 12070153 31462771 25241761 11722592 8710878 9794795 23268184 15284024 16189514 9535918 11594781
STAT3 STAT5B â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23073628 15790786 11369651 15007386 12481435 15526160 28403213 10358045 28192400 17546049 9355737
STAT3 STAT5A â—¼   PHYSICAL_INTERACTION 11.0 1.0 Reactome 23073628 15790786 11369651 15007386 12481435 15526160 28403213 10358045 28192400 17546049 9355737
YY1 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10787423 10634504 8816507 10505791 18391986
TP53 TP63 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 10606233 16931914 18388131 16516862 14576823 11382762 20442293 23019126 19858204 11238924 11423969
TP53 TP63 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11238924 18431400 16713569
TP53 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -3.51 3.5 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368