Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
H1-5 NEK9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-5 BICD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-5 RAN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-5 TTN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MYC CSN2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1508191 17512931
EML4 NEK6 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16890222 31409757
GABARAPL2 MLX â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
NUDCD2 HSP90AA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20133715 0914307107
MYC HSP90AB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11983916
SSRP1 MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9472631 12374749
PPP1CA MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23277204
MYC RAN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23468463 11085504
SSRP1 NEK9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218941 16902406
PLK1 NEK9 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 16079175 21642957
NEK9 CHK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 29262732 20562859
MYC PP1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
PP1A NEK9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25593058 29669786
MLP3A NEK9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24067654 20562859
DYL2 NEK9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 27173435
RN19B NEK9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MYC CDK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC NEK9 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
MYC SSRP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30415952 29467282
MAFF NEK9 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
EP300 VHL â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
DYL1 NEK7 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 27173435 32707033
NEK7 NEK8 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 27173435 32707033
GBRAP NEK9 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31857374 20562859
EP300 RAN â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33742100 12649209
NEK6 NEK7 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
SUPT16H SSRP1 â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 5218941 16902406
NEK9 DYL1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 27173435 20562859 25852190 26496610
NEK6 DYL1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 32707033 17353931
NEK9 BICD2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11864968 30021884
MYC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12776737 16287840 32140074 15616592 16126174 17157259
EP300 MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
GBRL2 NEK9 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20562859 17353931
MYC PLK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29467282 27773673 30415952 17314511 33494392
NEK9 SSRP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 14660563 16902406
DYNLL1 DYNLL2 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
HSP90AA1 HSP90AB1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
DYL1 DYL2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 27173435 26344197 17353931
PLK1 BICD2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28718761 26186194 25659891 28514442 32707033 26291670 19596235
PPP1R13L PPP1CA â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 21998301 270751 8217559
PPP1CA PPP1R13L â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
BAG3 MDFI â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
NEK9 NEK7 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 27173435 20562859 12840024 32707033
MYC BCL3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12695333
CCNB1 NEK9 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16079175 12101123 21642957
CCNB2 NEK9 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16079175 12101123 21642957
CDK1 NEK9 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 16079175 12101123 21642957
MDM2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9809062 11070080 16713569
MYC HSP90AA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 28914785 12644583
NEK9 NEK6 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17353931 20873783 12840024 26186194 12101123 28514442 32707033
MDFI PELI2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HuRI 32296183
PLK1 CCNB1 â—¼   PHOSPHORYLATION ✅ + 0.91 0.91 Signor 11242082
DYNLL1 GABARAPL2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
SSRP1 SUPT16H â—¼   CORRELATES + 0.91 0.91 CCLE 31978347
NEK7 NEK9 â—¼   PHYSICAL_INTERACTION 928.0 0.92 STRING 36370105
DYNLL2 GABARAPL2 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HuRI 32296183
CCNB2 CDK1 â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
SSRP1 SUPT16H â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CCNB1 CDK1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
NEK9 NEK7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19369195 18691976 12840024 18452278
HSP90AA1 CBL â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 17177598 16187797 15284455 16849543 16969069 16953218 17699773 17372273 17712310
MYC CCNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12747840 11522645 11983916 19470724
CDK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 17145710 23799914 34224728 20117088 16784539 24358021 24508230 19470789 10973963 17283331 20228808 18347064 11242082 12397081 10362260 24582498 15582998 20367638 1833185 12447691 9001210 2570636 24101512 23543736 11331587 12524548 22726437 27626412
PLK1 CCNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 20404109 16854412 26899266 19364923 25362646 20126263 12524548 26729093 11242082 12447691
CDK1 PLK1 â—¼   ENZYMATIC_REACTION ✅ 22.0 1.0 ACSN 12124778 14551205 14614141 15242590 15279786 15375219 15377654 15485915 15917306 16713580 16818604 17303408 17596790 17660363 18414028 18543256 18590585 18995830 19652693 19686080 7575488 9892021
MYC CDK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18802399 2237430 8065306 11085504
CDK1 PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 12202491 17145710 17274640 22367880 18088087 17202132 9122166 97225924 10880350
CDK1 PLK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 19652693 18590585 7575488 17303408 12124778 17764786 17660363 15279786 15917306
CDK1 CHEK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 20798862 19837665 18691976 21765472 21907702 29092815 18983824 16629900 22686412 24242917
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
MYC MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15655352 12695333 19649205 10348347
PLK1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 12383858 19833129 23948487 24265276 26754547
MYC MTHFD1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12747840 12808131 18414489
PLK1 MYC â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11073952 17596790 18931676 19270156 19622404 19686080 8127874
MYC VHL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22286234 12695333
PLK1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18931676 19270156 25915540 23887393 19622404 19686080
NEK9 NEDD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22818914
NEK9 NEK6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 17145710 12840024 26186194 17353931 19369195 19690332 12101123 20873783
PAK4 RAN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20805321 22960742 23162738
PLK1 RAN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 20805321 16930555