Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NEDD8 CUL1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 0806155105 18723677
CUL4A UBC12 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32494016 28581483 21987584
UBC12 CUL3 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 21247897 28581483 26286618 28475037
CUL3 CUL5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 22709582
CUL5 DCA11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31253590 21145461
CUL2 CSN7B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 33961781
CUL2 CSN4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 19295130
CUL2 UBC12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 28581483
DET1 CSN3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
APBB3 CSN3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBX7 CSN3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NEDD8 CSN3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16503656 21145461
KLH10 CSN3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DENR CSN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KLH10 CSN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NEDD8 CSN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16503656 21145461
APBB3 CSN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CRBN CSN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24292625 27029275
DET1 CSN2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KLH10 CUL3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
NEDD8 DCA11 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 18247557
NEDD8 CSN4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16503656 21145461
NEDD8 CSN7A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16503656 21145461
DENR CSN5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DENR CSN6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DENR BTBD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DENR CSN7B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DENR CSN4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DENR CSN7A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CRBN CSN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24292625 27029275
CRBN CSN7A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24292625 27029275
CSN7A DCAF4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
CSN8 DCAF4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DCAF4 CSN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DCAF4 CSN7B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DCAF4 CSN4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DET1 CSN6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DET1 CSN7B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DET1 CSN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DET1 CSN7A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DET1 CSN5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DET1 CSN4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CSN7B BTBD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CSN8 BTBD1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BTBD1 CSN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KLH10 CSN5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
APBB3 CSN5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
APBB3 CSN4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBX7 CSN4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KLH10 CSN4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
APBB3 CSN7A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KLH10 CSN7A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBX7 CSN7A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBX7 CSN7B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
FBX7 CSN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
DCA11 CSN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KLH10 CSN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
APBB3 CSN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KLH13 CSN1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 33961781
KLH10 CSN6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
APBB3 CSN6 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KLH13 CSN8 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 33961781
APBB3 CSN7B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
KLH10 CSN7B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CUL4B CSN1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22038470 31973889 16861906 26496610 33961781 21145461 34026424
CUL5 CSN7B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31253590 21145461 33961781
DDB2 CSN2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 16260596 12732143 33961781 26186194 19295130
DDB2 CSN8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 16260596 26496610 12732143 33961781 26186194
DDB2 CSN7B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
DDB2 CSN3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16260596 26496610 12732143 33961781 19295130
DDB2 CSN7A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 16260596 26496610 12732143 33961781 26186194
DDB2 CSN4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 16260596 26496610 12732143 33961781 26186194 19295130
CUL4A CSN4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 17079684 31973889 18606781 16964240 21145461 19295130
CSN3 BTBD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 19295130 26186194 33961781
CSN3 CRBN â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24292625 19295130 27029275
CSN3 DCA11 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 19295130 26186194 33961781
CSN3 DCAF4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
DCA11 CSN2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 19295130 26186194 33961781
FBX17 CSN2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
UBC12 CSN2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 28581483 33961781
CSN2 DCAF4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CSN2 BTBD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CSN2 FBX7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CUL3 CSN8 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 21145461 33961781 26286618
CSN4 CRBN â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 24292625 19295130 27029275
CSN4 BTBD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 19295130 33961781
UBC12 BTBD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 28581483 33961781
CSN7A BTBD1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26496610
UBC12 CSN5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 28581483 33961781
UBC12 CSN4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 28581483 33961781
CSN4 DCA11 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 19295130 33961781
CSN4 FBX17 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 19295130 26186194 33961781
UBC12 CSN7A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 28581483 33961781
CSN7A DCA11 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 19295130 26496610 33961781
FBX17 CSN7B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
UBC12 CSN1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 28581483 33961781
UBC12 CSN7B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 28581483 33961781
CSN7B DCA11 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 27173435
CSN8 CUL5 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31253590 21145461 30587576 11337588
CSN4 CUL5 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31253590 21145461 11337588
CSN1 CUL5 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31253590 21145461 11337588
CSN3 CUL5 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31253590 21145461 19295130 11337588
CSN5 CUL5 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31253590 30587576 31950832 21145461 11337588
CSN7A CUL5 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31253590 21145461 33961781 11337588
STK11 CSN4 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 25852190
CSN1 CUL2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21145461 33961781 11337588
CUL3 BTBD1 â—¼   PHYSICAL_INTERACTION ✅ 0.84 0.84 mint 34591642
CSN4 P53 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22653443 11285227 24725084
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
DET1 CUL4B â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 33961781 16949367 31973889
STK11 CSN3 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 33961781 25852190
CUL4A DCAF4 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
NEDD8 CUL4B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16503656 18274552 31973889 24654937 16620772 23201271 10597293 21145461
CSN2 CUL5 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31253590 21145461 32047038 11337588
CUL3 CUL1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21145461 26344197
CUL4B CSN7A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31973889 26496610 33961781 21145461 19295130
CUL4B CSN7B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 31973889 33961781 24981860 21145461
CUL4B CSN8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 31973889 26496610 33961781 27173435 24981860 21145461
CUL4A CSN7B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17079684 28514442 31973889 18606781 33961781 16964240 21145461 19295130
CUL4A CSN8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17079684 28514442 31973889 18606781 33961781 27173435 16964240 21145461 19295130
CUL4A CUL1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17079684 21145461 32235678
CUL4A CSN7A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17079684 31973889 18606781 26496610 16964240 21145461 19295130
CUL4A CSN3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16036220 17079684 28514442 31973889 18606781 33961781 26186194 16964240 21145461 19295130
CSN3 CUL2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16036220 28514442 33961781 26186194 21145461 19295130
CUL2 CSN7A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21145461 19295130 26496610
CUL2 CSN8 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21145461 33961781 27173435
CSN3 CUL3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16036220 28514442 33961781 21145461 19295130
CUL1 CSN7B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21145461 29103612 27833851
CUL3 CSN7B â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21145461 27833851 33961781
CUL3 CSN4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21145461 19295130 33961781
CUL3 CSN7A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 27833851 33961781 21145461 19295130
CSN5 CRBN â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21145461 24292625 31950832 27029275
CSN8 CRBN â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 24292625 27029275
CSN5 DCAF4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21145461 19615732 33961781
CSN6 DCAF4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26186194 21145461 19615732
CSN5 BTBD1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 26186194 21145461 19295130
CSN5 FBX7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21145461 33961781
CSN5 DCA11 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28446751 31950832 19295130 21145461 19615732
CSN7B CSN7A â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 22863883 33961781
CSN6 DCA11 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 28446751 33961781 26186194 19295130 21145461 19615732
CSN6 UBC12 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 21145461 28581483 33961781
CSN8 DCA11 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 33961781 27173435
CUL4B DCAF4 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
DCA11 CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 28446751 31973889 26496610 33961781 31155351 21145461 34026424 16949367
CRBN CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 24292625 31973889 33961781 21145461 27142104 27294876
DCAF4 CUL4B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 28446751 31973889 26496610 33961781 21145461 30945288 16949367 32140073
CUL4B CSN2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 31973889 16861906 26496610 33961781 24981860 26186194 21145461
DET1 CUL4A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781 17452440 16964240 14739464 16949367
CUL4A NEDD8 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16503656 19617556 22474075 18274552 31973889 24654937 16620772 12481031 19295130 23201271 16964240 10597293 21145461 18247557
CUL4A DCA11 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17079684 28514442 27203182 31973889 28453520 32235678 31155351 33961781 16964240 21145461 19295130 30945288 16949367
CUL4A DCAF4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 31973889 33961781 16964240 21145461 30945288 16949367 32140073
CSN2 CUL2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 26976604 22013077 11967155 26186194 33961781 31444342 21145461 32047038
CSN3 CSN7B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 20399188 27833851 33961781 26186194 24981860 22939629 19295130 32034103
CSN3 CUL1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16036220 19141280 29103612 21145461 19295130
KLH13 CSN2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21145461 19615732
CSN2 CUL3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 26976604 33961781 21145461 19295130 16045761 32047038
CSN2 CSN7B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 22863883 27833851 27173435 26186194 33961781 31444342 22939629 26344197 32034103
CSN1 CUL1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16036220 19141280 34237211 21169563 29103612 21145461 11337588
CSN7A CUL1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 19141280 12628923 27833851 29103612 21145461
CUL1 UBC12 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21247897 12565873 18805092 18826954 19245792 17914462 27591266 28581483 28475037 24949976 27348078 21946088
CUL1 CSN4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16036220 19141280 29103612 21145461 19295130
NEDD8 CSN1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21145461 27029275
CSN5 KLH13 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21145461 19615732
KLH13 CSN4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21145461 19615732
CSN4 CSN7B â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 22863883 27833851 27173435 33961781 22939629 19295130 26344197 32034103
CSN6 KLH13 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 21145461 19615732
CUL4B DDB2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
CSN3 CUL4B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16036220 28514442 31973889 23238014 26496610 22863883 33961781 24981860 26186194 21145461 19295130
CUL4A CUL4B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17041588 31973889 23555860 18593899 33961781 16964240 21145461 30945288 32140073
CSN5 CUL4B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 34026424 31973889 23238014 18850735 23357576 26496610 33961781 26186194 19615732 21145461 19295130 30945288
CUL4B CSN4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31973889 23238014 28225217 26496610 24292684 33961781 24981860 21145461 19295130
CSN6 CUL5 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31253590 33961781 19295130 21145461 19615732 11337588
CSN6 DDB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 16260596 26496610 12732143 33961781 19295130 26186194 21145461 19615732
STK11 P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 16713569 28628118 28205554 21317932 33961781 11430832
CSN1 CUL4A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17079684 31973889 18606781 26976604 27029275 33961781 21145461 22414063
CSN5 CUL4A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17079684 28514442 22474075 18606781 18850735 23357576 22956996 12732143 27029275 26976604 33961781 26186194 19615732 16964240 25349427 21145461 19295130 32047038
CSN6 CUL4A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17079684 28514442 22474075 31973889 18606781 33179082 33961781 19295130 26186194 16964240 21145461 19615732 30945288
CUL4A CSN2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31973889 18606781 32493769 26976604 27029275 33961781 26186194 16964240 25349427 21145461 19295130 32047038
CUL4A CRBN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 24292623 24292625 31973889 32235678 23983124 26231201 25860244 26990986 27029275 33961781 16964240 32132601 21145461 27142104 20223979 27294876
CSN6 CUL2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194 19295130 21145461 19615732
CSN5 CUL2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 18850735 22956996 22013077 19615732 21145461 19295130
CUL1 CSN2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16036220 19141280 26976604 29103612 11967155 21145461 16045761 32047038
FBX17 CUL1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 18203720 29103612 33961781 26186194 21145461
CUL1 CSN8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19141280 29103612 22959436 18173839 21145461
CSN6 CUL3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 19295130 21145461 19615732
CSN1 CUL3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 27029275 33961781 21145461 11337588
CSN5 CUL3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 18850735 22013077 33961781 19615732 29897280 21145461 19295130 32047038
CUL3 BTBD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 19995937 25011449 17543862 33961781 21145461 19295130
CUL3 KLH13 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19995937 30190310 33872809 31515271 17543862 33130828 21145461 19295130
CSN6 NEDD8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16503656 24654937 25144743 21145461 19615732
CSN5 NEDD8 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16503656 24654937 25144743 21145461 19615732
NEDD8 P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22836579 17098746 15242646 22653443 17369817 21887275 24654937 20101219 22895816 16620772 32807901 22370482 17546054
CSN6 BTBD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194 21145461 19615732
CSN5 FBX17 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194 21145461 19615732
CSN7A CSN4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17403899 19141280 11285227 9707402 10903862 26496610 22863883 26344197 27833851 22939629 19295130 23086934 14647295 11337588
CSN6 FBX7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 21145461 19615732 33961781
CSN6 FBX17 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 33961781 26186194 21145461 19615732
CSN8 CSN7B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 9707402 27833851 27173435 33961781 26344197
CUL4A NEDD8 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CSN6 CUL4B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 31973889 26496610 22863883 33961781 26186194 19295130 21145461 19615732
CUL4B DDB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17041588 31973889 18593899 26496610 30923324 33961781 26186194 21145461 30945288 16949367
NEDD8 CUL5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28522566 24076655 28514442 31253590 18805092 18274552 22405651 21119685 24654937 33961781 20847044 23201271 10597293 21145461 18247557
CSN5 DDB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 16260596 28514442 18850735 26496610 12732143 33961781 32985517 26186194 21145461 19615732
CUL4A DDB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 17079684 28514442 22118460 28035050 11564859 21145461 29262658 16473935 15811626 18593899 26496610 30923324 16964240 20368362 19295130 16751180 33759138 16260596 27203177 17609381 32985517 10585395 17041588 31973889 12732143 33961781 26186194 17626091 30945288 16949367
CSN7A CSN3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16036220 28514442 20399188 25043011 11285227 10903862 26496610 22863883 27833851 33961781 26186194 24421388 22939629 19295130 26344197 11337588
CSN7A CSN2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 25043011 12628923 11285227 10903862 26496610 22863883 27833851 33961781 26186194 22939629 19295130 26344197 11337588
CSN6 CUL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22474075 19141280 34237211 29103612 19295130 21145461 19615732 11337588
FBX7 CUL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 10531035 15145941 27503909 34060591 27497298 26496610 29103612 16278047 18495667 33961781 21145461
CSN5 CUL1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21903097 21145461 22474075 22767593 26265931 22013077 16036220 21249194 19141280 31950832 24973710 22959436 27774986 29863914 25144743 19615732 34237211 18850735 22956996 29103612
CSN6 CRBN â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24292625 27029275 19295130 21145461 19615732
CSN7A CSN5 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 12628923 21145461 20399188 11285227 26496610 19295130 19656241 17403899 31950832 10903862 27833851 22939629 19615732 11337588 18850735 17429597 22863883 33961781 26186194 26344197
CSN5 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28539160 11285227 17879958 16936264 24725084 16624822
CSN5 CSN7B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 22939629 20399188 31950832 18850735 22863883 27833851 27173435 26186194 19615732 16624822 31444342 33961781 21145461 19295130 32034103
CSN6 CSN7A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17403899 19141280 25043011 10903862 26496610 22863883 27833851 33961781 19295130 26186194 21145461 19615732 23086934 26344197
CSN7A CSN1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20399188 25043011 11285227 10903862 26496610 14681455 27029275 22863883 27833851 33961781 22939629 26344197 11337588
CSN8 CSN7A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 17403899 25043011 11285227 10903862 9707402 26496610 22863883 27833851 33961781 19295130 23213463 26344197 11337588
CSN1 CSN7B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 20399188 14681455 27833851 33961781 22939629 22414063 32034103
CSN6 CSN7B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 22863883 27833851 27173435 26186194 19295130 33961781 21145461 19615732 26344197 32034103
CUL4A DET1 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
CRBN CUL4A â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
CUL4A DDB2 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
CUL3 NEDD8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CSN4 CSN3 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 16036220 28514442 20399188 25043011 11285227 9707402 32034103 22863883 26344197 33961781 26186194 24981860 22939629 19295130 14647295 11337588
NEDD8 CUL2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16503656 23401859 19617556 18826954 18274552 21145461 10318914 24654937 16620772 23201271 31444342 18173839 10597293 10585493 18247557 17132228
NEDD8 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 6541102 18274552
CUL3 NEDD8 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16503656 19617556 18826954 23936405 18274552 17192413 24654937 17543862 16620772 23201271 33961781 10597293 21145461 18247557 10500095
CSN4 CSN5 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 21145461 32034103 20399188 11285227 9707402 19295130 14647295 31950832 16624822 19615732 11337588 18850735 22863883 33961781 27173435 26186194 24725084 23086934 26344197
CSN8 CSN4 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 25043011 11285227 9707402 22863883 26344197 27173435 33961781 24981860 22939629 19295130 23086934 14647295 11337588
CSN8 CSN3 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 32034103 32296183 20399188 11285227 9707402 19295130 16036220 19141280 25043011 22939629 11337588 22863883 33961781 27173435 26186194 31444342 24981860 26344197
CSN6 CSN3 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16036220 28514442 22939629 20399188 25043011 11285227 32034103 22863883 33961781 19295130 26186194 24421388 21145461 19615732 26344197 11337588
CSN3 CSN5 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 21145461 32034103 20399188 11285227 19295130 24421388 16036220 23636414 25043011 31950832 16624822 19615732 11337588 18850735 22863883 33961781 26186194 26344197
CSN3 CSN2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 16045761 32034103 20399188 11285227 24421388 19295130 16036220 26456823 25043011 10903862 22939629 11337588 22863883 33961781 11967155 26186194 31444342 24981860 26344197
CSN8 CSN2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25043011 11285227 9707402 10903862 22863883 33961781 11967155 26186194 27173435 24981860 22939629 16045761 26344197 11337588
CSN6 CSN2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 22939629 25043011 11285227 10903862 32034103 22863883 33961781 27173435 26186194 19615732 21145461 19295130 16045761 26344197 11337588
CSN4 CSN2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25043011 11285227 9707402 10903862 32034103 22863883 26344197 27173435 26186194 33961781 31444342 24981860 22939629 19295130 16045761 14647295 11337588
CSN5 CSN2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 23408908 21145461 16045761 32034103 20399188 11285227 19295130 25043011 31950832 26976604 10903862 16624822 22939629 19615732 11337588 18850735 22863883 33961781 27173435 26186194 26344197
NEDD8 CUL1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16503656 18723677 16620772 23201271 21145461 22474075 18247557 24076655 10772955 17438373 19245792 24654937 21102408 10713156 11027288 21765416 10597293 22405651 12565873 18805092 18826954 18274552 19713960 16177058 22959436 24949976 32726803 19617556 17206147 10318914 17318178 21119685 18264111 18627766 23267066
UBC12 NEDD8 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16503656 28514442 25416956 10207026 16735510 16620772 23201271 10828074 21145461 19245792 24654937 21765416 18274552 17353931 19713960 28581483 30804002 23936405 18652489 18264111 33961781 9694792 23267066
CSN8 CSN5 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 23636414 20399188 25043011 31950832 11285227 18850735 9707402 33961781 27173435 19295130 26186194 21145461 19615732 11337588
CSN1 CSN5 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 27029275 14681455 21145461 32034103 20399188 11285227 23926101 24421388 22414063 25043011 31950832 19444310 16624822 19615732 11337588 18850735 33961781 26186194 26344197
CSN1 CSN4 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11114242 25043011 20399188 27029275 14681455 22863883 33961781 22939629 19295130 22414063 26344197 32034103
CSN6 CSN1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 19141280 25043011 20399188 11285227 27029275 14681455 32034103 33961781 26186194 24421388 21145461 19615732 22414063 11337588
CSN8 CSN1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 19141280 25043011 20399188 11285227 9707402 27029275 14681455 32034103 22863883 33961781 27173435 12324474 24421388 22414063 26344197 11337588
CSN8 CSN6 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 22939629 25043011 11285227 9707402 32034103 22863883 33961781 27173435 19295130 26186194 21145461 19615732 26344197 11337588
CUL2 NEDD8 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CUL5 NEDD8 â—¼   PHYSICAL_INTERACTION 979.0 0.98 STRING 36370105
CSN1 CSN3 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 27029275 14681455 32034103 20399188 11285227 24421388 22414063 16036220 11114242 19141280 25043011 10903862 22939629 11337588 22863883 33961781 26186194 31444342 26344197
CSN1 CSN2 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 27029275 14681455 16045761 32034103 32296183 20399188 11285227 24421388 22414063 11114242 19141280 25043011 10903862 22939629 11337588 22863883 33961781 26186194 31444342 26344197
CSN6 CSN5 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 12220626 21625211 21145461 32034103 20399188 11285227 19295130 19141280 25043011 31950832 25144743 22939629 19615732 11337588 18850735 22863883 33961781 27173435 26186194 26344197
CSN6 CSN4 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 21145461 32034103 32296183 11285227 9707402 19295130 14647295 19141280 25043011 22939629 19615732 11337588 22863883 33961781 27173435 26186194 31444342 23086934 26344197
NEDD8 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9694792 18805092 21145461 19250909 19231300
NEDD8 CUL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16620772 15688063 11696557 21145461
CUL1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792