Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NEDD8 CUL1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 intact 0806155105 18723677
CUL4A UBC12 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 28581483 32494016 21987584
UBC12 CUL3 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 28581483 21247897 26286618 28475037
CUL2 CSN4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19295130 21145461
CUL2 CSN7B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 21145461
CUL2 UBC12 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28581483 21145461
DET1 CSN5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
APBB3 CSN5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DENR CSN5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KLH10 CSN5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DCAF4 CSN4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
APBB3 CSN4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KLH10 CSN4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FBX7 CSN4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DET1 CSN4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DENR CSN4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NEDD8 CSN4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16503656 21145461
CSN7A DCAF4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 26496610
DET1 CSN7A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
APBB3 CSN7A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CRBN CSN7A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24292625 27029275
KLH10 CSN7A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NEDD8 CSN7A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16503656 21145461
DENR CSN7A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FBX7 CSN7A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FBX7 CSN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FBX7 CSN3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FBX7 CSN7B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
BTBD1 CSN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DCA11 CSN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DCAF4 CSN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KLH13 CSN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 21145461
DET1 CSN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
APBB3 CSN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KLH10 CSN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CRBN CSN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24292625 27029275
DET1 CSN6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KLH10 CSN6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
APBB3 CSN6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DENR CSN6 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CSN8 DCAF4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CSN8 BTBD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KLH13 CSN8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 21145461
NEDD8 DCA11 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21145461 18247557
CUL5 DCA11 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31253590 21145461
APBB3 CSN7B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CSN7B BTBD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DCAF4 CSN7B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DENR CSN7B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DET1 CSN7B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KLH10 CSN7B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KLH10 CSN3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KLH10 CUL3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
KLH10 CSN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
APBB3 CSN3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
APBB3 CSN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DENR BTBD1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CRBN CSN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24292625 27029275
DET1 CSN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DENR CSN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NEDD8 CSN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16503656 21145461
DET1 CSN3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NEDD8 CSN3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16503656 21145461
CUL3 CUL5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22709582 21145461
CUL4A CSN4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16964240 21145461 18606781 17079684 19295130 31973889
UBC12 CSN5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28581483 28514442 33961781
CSN4 FBX17 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 19295130 26186194
CSN4 CRBN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19295130 24292625 27029275
UBC12 CSN4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28581483 28514442 33961781
DDB2 CSN4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12732143 33961781 26496610 26186194 28514442 19295130 16260596
CSN4 DCA11 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 19295130
CSN4 BTBD1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 19295130
CSN7A DCA11 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 19295130 26496610
CSN7A BTBD1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26496610
DDB2 CSN7A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12732143 33961781 26496610 26186194 28514442 16260596
UBC12 CSN7A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28581483 28514442 33961781
CSN2 FBX7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
FBX17 CSN7B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
FBX17 CSN2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
UBC12 CSN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28581483 28514442 33961781
CUL4B CSN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 34026424 16861906 21145461 22038470 26496610 31973889
CUL3 CSN8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 26286618 21145461
DDB2 CSN8 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12732143 33961781 26496610 26186194 28514442 16260596
UBC12 BTBD1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28581483 28514442 33961781
UBC12 CSN2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28581483 28514442 33961781
UBC12 CSN7B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28581483 28514442 33961781
DCA11 CSN2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 19295130 26186194
CSN7B DCA11 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 27173435
CSN3 DCA11 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 19295130 26186194
CUL5 CSN7B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 31253590 21145461
DDB2 CSN7B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CSN3 BTBD1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 19295130 26186194
CSN2 BTBD1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CSN3 CRBN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19295130 24292625 27029275
DDB2 CSN2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12732143 33961781 26186194 28514442 19295130 16260596
CSN2 DCAF4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
DDB2 CSN3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12732143 33961781 26496610 19295130 16260596
CSN3 DCAF4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
CSN1 CUL2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 11337588 21145461
CSN5 CUL5 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 30587576 31950832 21145461 11337588 31253590
CSN4 P53 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11285227 24725084 22653443
STK11 CSN4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25852190 32707033
CSN4 CUL5 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31253590 11337588 21145461
CSN7A CUL5 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 31253590 11337588 21145461
CSN1 CUL5 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31253590 11337588 21145461
CSN8 CUL5 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 30587576 31253590 11337588 21145461
CSN3 CUL5 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19295130 31253590 11337588 21145461
STK11 CSN3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25852190 32707033 33961781
DET1 CUL4B â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 28514442 16949367 31973889
CUL4A DCAF4 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
CUL3 CUL1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26344197 21145461
CSN2 CUL5 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 32047038 31253590 11337588 21145461
NEDD8 CUL4B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24654937 10597293 18274552 21145461 16503656 23201271 31973889 16620772
CUL4A CUL1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17079684 32235678 21145461
CUL1 CSN7B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 27833851 29103612 21145461
CSN3 CUL2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 21145461 26186194 28514442 19295130 16036220
CUL2 CSN8 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 27173435 21145461
CUL2 CSN7A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19295130 26496610 21145461
CUL4A CSN3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 16964240 21145461 18606781 26186194 17079684 28514442 19295130 31973889 16036220
CUL4A CSN7A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16964240 21145461 26496610 18606781 17079684 19295130 31973889
CUL4A CSN8 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 27173435 16964240 21145461 18606781 17079684 28514442 19295130 31973889
CUL4A CSN7B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 16964240 21145461 18606781 17079684 28514442 19295130 31973889
CSN5 FBX7 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 21145461
CSN5 BTBD1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 21145461 26186194 28514442 19295130
CSN5 DCAF4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19615732 28514442 33961781 21145461
CSN5 DCA11 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28446751 31950832 21145461 19615732 19295130
CSN5 CRBN â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 24292625 27029275 31950832 21145461
CUL3 CSN4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 19295130 21145461
CSN7B CSN7A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 22863883
CUL4B CSN7A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 21145461 26496610 19295130 31973889
CUL3 CSN7A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 21145461 27833851 28514442 19295130
CSN6 DCA11 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28446751 21145461 19615732 26186194 28514442 19295130
CSN6 DCAF4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 21145461 19615732 26186194 28514442
CSN6 UBC12 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28581483 28514442 33961781 21145461
CUL4B CSN8 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 27173435 24981860 21145461 26496610 28514442 31973889
CSN8 DCA11 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 27173435
CSN8 CRBN â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 24292625 27029275
CUL3 CSN7B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 27833851 21145461
CUL4B CSN7B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 21145461 28514442 31973889
CSN3 CUL3 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 21145461 28514442 19295130 16036220
CUL4B DCAF4 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
CSN1 CUL1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21169563 19141280 29103612 21145461 34237211 11337588 16036220
CSN3 CUL1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19141280 29103612 21145461 19295130 16036220
CSN7A CUL1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29103612 19141280 21145461 12628923 27833851
CUL1 CSN4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19141280 29103612 21145461 19295130 16036220
CUL1 UBC12 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18805092 17914462 27591266 18826954 27348078 19245792 28475037 12565873 21247897 24949976 28581483 21946088
CSN2 CUL2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 26976604 31444342 21145461 32047038 11967155 22013077 26186194 28514442
DET1 CUL4A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 16964240 16949367 14739464 17452440 28514442
CUL4A DCA11 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 27203182 16964240 21145461 32235678 28453520 16949367 17079684 30945288 28514442 19295130 31155351 31973889
CSN5 KLH13 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19615732 21145461
CSN4 CSN7B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 27173435 26344197 27833851 22939629 22863883 32034103 28514442 19295130
KLH13 CSN4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19615732 21145461
NEDD8 CSN1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 27029275 21145461
CSN6 KLH13 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19615732 21145461
KLH13 CSN2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19615732 21145461
DCA11 CUL4B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28446751 34026424 21145461 26496610 16949367 28514442 31155351 31973889
CSN2 CSN7B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 27173435 31444342 26344197 27833851 22939629 26186194 32034103 28514442 22863883
CSN3 CSN7B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 24981860 22939629 27833851 20399188 26186194 32034103 28514442 19295130
CUL4B CSN2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 24981860 16861906 21145461 26496610 26186194 28514442 31973889
CSN2 CUL3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 26976604 21145461 32047038 16045761 28514442 19295130
DCAF4 CUL4B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28446751 21145461 26496610 32140073 16949367 30945288 28514442 31973889
CUL4B DDB2 â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
FBX17 CUL1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 29103612 21145461 26186194 18203720 28514442
CUL1 CSN2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26976604 19141280 29103612 21145461 32047038 11967155 16045761 16036220
CUL1 CSN8 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19141280 29103612 21145461 18173839 22959436
CSN5 CUL2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21145461 19615732 22013077 22956996 19295130 18850735
CSN6 CUL2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21145461 19615732 26186194 28514442 19295130
CSN1 CUL4A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26976604 21145461 27029275 22414063 18606781 17079684 31973889
CSN5 CUL4A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12732143 26976604 33961781 16964240 21145461 19615732 32047038 27029275 25349427 18606781 23357576 17079684 26186194 22956996 28514442 19295130 18850735 22474075
CSN6 CUL4A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 16964240 21145461 19615732 18606781 26186194 17079684 30945288 28514442 19295130 33179082 31973889 22474075
CUL4A CRBN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 20223979 26990986 24292623 27294876 16964240 21145461 24292625 27142104 27029275 32235678 25860244 32132601 26231201 23983124 28514442 31973889
CUL4A CSN2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26976604 16964240 21145461 32047038 27029275 25349427 18606781 26186194 32493769 28514442 19295130 31973889
CSN5 CUL4B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 34026424 23238014 19615732 21145461 26496610 23357576 26186194 30945288 28514442 19295130 18850735 31973889
CSN5 CUL3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21145461 19615732 32047038 22013077 28514442 19295130 18850735 29897280
CSN5 NEDD8 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24654937 25144743 19615732 21145461 16503656
CSN5 FBX17 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21145461 19615732 26186194 28514442
STK11 P53 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 16189514 11430832 28205554 28628118 16713569 21317932
NEDD8 P53 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24654937 22836579 17546054 21887275 22370482 32807901 22653443 17098746 17369817 20101219 22895816 15242646 16620772
CUL4B CSN4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 28225217 24981860 21145461 26496610 24292684 19295130 23238014 31973889
CSN7A CSN4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11285227 19141280 9707402 26344197 22939629 26496610 27833851 11337588 10903862 14647295 22863883 23086934 19295130 17403899
CSN6 FBX7 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19615732 28514442 33961781 21145461
CSN6 FBX17 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21145461 19615732 26186194 28514442
CSN1 CUL3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21145461 27029275 11337588 28514442
CSN6 CUL5 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21145461 19615732 11337588 31253590 19295130
CSN6 BTBD1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21145461 19615732 26186194 28514442
CSN6 DDB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12732143 33961781 21145461 19615732 26496610 26186194 28514442 19295130 16260596
CSN6 CUL3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 21145461 19615732 28514442 19295130
CSN6 NEDD8 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24654937 25144743 19615732 21145461 16503656
CSN8 CSN7B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 27173435 9707402 26344197 27833851 28514442
CUL3 KLH13 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17543862 33872809 21145461 19995937 33130828 30190310 19295130 31515271
CUL3 BTBD1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 17543862 32296183 21145461 19995937 25011449 28514442 19295130
CSN3 CUL4B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 24981860 21145461 26496610 22863883 26186194 28514442 19295130 23238014 31973889 16036220
CUL4A NEDD8 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
CSN6 CUL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19141280 29103612 21145461 19615732 34237211 11337588 19295130 22474075
FBX7 CUL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15145941 33961781 29103612 27503909 21145461 26496610 27497298 10531035 16278047 34060591 28514442 18495667
CSN5 CUL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34237211 21903097 26265931 29103612 21249194 27774986 25144743 19615732 22767593 24973710 22959436 22956996 18850735 31950832 19141280 21145461 22013077 29863914 22474075 16036220
CSN7A CSN5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 22939629 26496610 17429597 22863883 19656241 26344197 12628923 20399188 19295130 19615732 27833851 28514442 18850735 11285227 31950832 21145461 11337588 10903862 26186194 17403899
CSN5 CSN7B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 16624822 27173435 31444342 31950832 21145461 19615732 22939629 27833851 20399188 22863883 26186194 32034103 28514442 19295130 18850735
CSN5 P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11285227 16624822 28539160 24725084 16936264 17879958
CSN5 DDB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12732143 33961781 21145461 19615732 32985517 26496610 16260596 26186194 17079684 28514442 18850735
CSN7A CSN3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25043011 11285227 26344197 22939629 26496610 27833851 11337588 24421388 20399188 10903862 22863883 26186194 28514442 19295130 16036220
CSN8 CSN7A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25043011 11285227 9707402 26344197 27833851 26496610 11337588 10903862 22863883 23213463 28514442 19295130 17403899
CSN6 CSN7A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25043011 19141280 26344197 21145461 19615732 27833851 26496610 10903862 22863883 26186194 23086934 28514442 19295130 17403899
CSN7A CSN1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14681455 25043011 11285227 33961781 26344197 22939629 26496610 27833851 11337588 20399188 27029275 10903862 22863883
CSN7A CSN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25043011 11285227 26344197 12628923 22939629 26496610 27833851 11337588 10903862 22863883 26186194 28514442 19295130
CSN1 CSN7B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 14681455 33961781 22939629 27833851 22414063 20399188 32034103 28514442
CSN6 CSN7B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 27173435 26344197 21145461 19615732 27833851 22863883 26186194 32034103 28514442 19295130
CSN6 CUL4B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21145461 19615732 26496610 22863883 26186194 28514442 19295130 31973889
CSN6 CRBN â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21145461 19615732 24292625 27029275 19295130
NEDD8 CUL5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18805092 24654937 33961781 18274552 10597293 21119685 21145461 23201271 24076655 18247557 28522566 22405651 31253590 28514442 20847044
CUL4A DET1 â—¼   PHYSICAL_INTERACTION 903.0 0.9 STRING 36370105
CRBN CUL4A â—¼   PHYSICAL_INTERACTION 911.0 0.91 STRING 36370105
CUL4A DDB2 â—¼   PHYSICAL_INTERACTION 925.0 0.92 STRING 36370105
CUL3 NEDD8 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
CSN4 CSN3 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 33961781 25043011 11285227 9707402 26344197 24981860 22939629 11337588 20399188 14647295 22863883 26186194 32034103 28514442 19295130 16036220
NEDD8 CUL2 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 23401859 24654937 18274552 10597293 10318914 21145461 31444342 18826954 16503656 23201271 18247557 19617556 18173839 17132228 10585493 16620772
CSN4 CSN5 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 32034103 22863883 26344197 20399188 19295130 16624822 19615732 28514442 18850735 11285227 27173435 31950832 9707402 21145461 24725084 11337588 14647295 26186194 23086934
CSN8 CSN4 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 25043011 11285227 27173435 9707402 26344197 24981860 22939629 11337588 14647295 22863883 23086934 28514442 19295130
NEDD8 CUL1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21765416 16177058 18723677 18627766 17438373 32726803 24654937 11027288 18274552 10772955 16503656 24076655 18247557 22405651 17318178 10713156 19713960 10318914 21102408 23267066 23201271 22959436 17206147 16620772 18805092 10597293 21119685 21145461 18826954 19245792 19617556 12565873 18264111 24949976 22474075
CSN8 CSN5 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 25043011 11285227 27173435 31950832 9707402 21145461 19615732 11337588 20399188 26186194 28514442 19295130 18850735 23636414
CSN1 CSN5 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 32034103 14681455 26344197 27029275 24421388 20399188 16624822 19615732 22414063 28514442 18850735 25043011 11285227 31950832 23926101 19444310 21145461 11337588 26186194
CSN3 CSN5 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 32034103 22863883 26344197 24421388 20399188 19295130 16624822 19615732 28514442 18850735 23636414 25043011 11285227 31950832 21145461 11337588 26186194 16036220
CSN5 CSN2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 22939629 32034103 22863883 23408908 26344197 20399188 19295130 26976604 16624822 19615732 16045761 28514442 18850735 25043011 11285227 27173435 31950832 21145461 11337588 10903862 26186194
CSN1 CSN4 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 14681455 25043011 33961781 11114242 26344197 22939629 27029275 22414063 20399188 22863883 32034103 19295130
CSN4 CSN2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 25043011 11285227 27173435 31444342 9707402 26344197 24981860 32034103 22939629 11337588 10903862 14647295 22863883 26186194 16045761 28514442 19295130
CSN8 CSN1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 14681455 25043011 11285227 27173435 19141280 9707402 26344197 33961781 12324474 27029275 22414063 11337588 24421388 20399188 32034103 28514442 22863883
CSN6 CSN1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 14681455 25043011 11285227 33961781 19141280 21145461 19615732 27029275 22414063 11337588 24421388 20399188 26186194 32034103 28514442
CSN8 CSN6 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 25043011 11285227 27173435 9707402 26344197 21145461 19615732 22939629 11337588 22863883 26186194 32034103 28514442 19295130
CSN6 CSN2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 25043011 11285227 27173435 32034103 26344197 21145461 19615732 22939629 11337588 10903862 22863883 26186194 16045761 28514442 19295130
CSN6 CSN3 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 25043011 11285227 26344197 21145461 19615732 22939629 11337588 20399188 24421388 22863883 26186194 32034103 28514442 19295130 16036220
CSN8 CSN3 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 24981860 22939629 32034103 22863883 26344197 20399188 19295130 32296183 28514442 25043011 11285227 27173435 19141280 9707402 31444342 11337588 26186194 16036220
CSN8 CSN2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 25043011 11285227 27173435 9707402 26344197 24981860 11967155 22939629 11337588 10903862 26186194 16045761 28514442 22863883
UBC12 NEDD8 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21765416 33961781 16735510 28581483 24654937 18274552 16503656 10828074 18652489 23936405 19713960 17353931 23267066 23201271 9694792 28514442 25416956 30804002 16620772 21145461 19245792 18264111 10207026
CSN3 CSN2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 24981860 22939629 32034103 22863883 26456823 26344197 24421388 20399188 19295130 16045761 28514442 25043011 11285227 31444342 11967155 11337588 10903862 26186194 16036220
CUL2 NEDD8 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
CUL5 NEDD8 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
CSN6 CSN5 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 22939629 32034103 22863883 26344197 20399188 19295130 12220626 25144743 19615732 28514442 18850735 25043011 11285227 27173435 19141280 31950832 21145461 11337588 26186194 21625211
CSN6 CSN4 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 22939629 32034103 22863883 26344197 19295130 32296183 19615732 28514442 25043011 11285227 27173435 19141280 9707402 31444342 21145461 11337588 14647295 26186194 23086934
CSN1 CSN2 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 22939629 32034103 22863883 14681455 26344197 27029275 24421388 20399188 11114242 32296183 22414063 16045761 28514442 25043011 11285227 19141280 31444342 11337588 10903862 26186194
CSN1 CSN3 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 33961781 22939629 32034103 22863883 14681455 26344197 27029275 24421388 20399188 11114242 22414063 28514442 25043011 11285227 19141280 31444342 11337588 10903862 26186194 16036220
CUL1 NEDD8 â—¼   PHYSICAL_INTERACTION 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   SHARES_COMPLEX 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
CUL1 NEDD8 â—¼   ENZYMATIC_REACTION ✅ 61.0 1.0 ACSN 10023660 10671552 11348595 11900249 11955436 11967263 12051714 12648680 12820959 15001769 15071497 15340381 15459660 15688063 15703371 16039586 16697054 16713974 16940750 17143292 17652783 17884153 17928543 17936032 18196958 18805092 18931676 19250909 19258535 19270156 19352404 19366350 19411070 19576224 19597341 19619488 19622404 19686080 19751508 19809470 19836308 19847258 19849719 20006983 20558317 20705860 20843316 20976471 21411632 22270359 22682247 22730322 23343194 23732914 24023259 25730849 26885856 7542250 7641885 8666229 9694792
NEDD8 CUL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16620772 15688063 11696557 21145461
NEDD8 CUL4A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 9694792 18805092 21145461 19250909 19231300
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368