Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
XRCC4 ACTN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
BTRC SKP1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
MAPK8 CFLAR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18471544
COPB1 SUN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7993392 20551905
DDX3X EIF4A1 â—¼   COLOCALIZATION 2.0 0.8 intact 8407815 22872150
EIF1AD RPS20 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SH3GL3 EMD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
LMNA EMD â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 30488537
HMGN2 SYNE1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HMGN2 SUN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA5 YWHAB â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217174 15324660
HSPA5 SYNE2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
KPNA2 SUN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7993392 20551905
RYBP LMNA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
POLR1E MYO1C â—¼   COLOCALIZATION 2.0 0.8 intact 16514417 5218407
PDIA6 SUN2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SUN2 SYNE4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
CCDC155 SUN2 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
EIF4A1 RPS20 â—¼   PHYSICAL_INTERACTION 804.0 0.8 STRING 36370105
MDC1 LMNA â—¼   KO_UP_REGULATES ✅ + 0.8 0.8 PKG 28854368
SUN2 SYNE3 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ESR1 YWHAB â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
ZNRF4 SUN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZNRF4 SGPL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RAC2 RAC3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PI42A PI42B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SUN2 PI42B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SUN2 PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CSN7B SUN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SUN2 PI42A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MPPE1 CGAT2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CGAT2 SUN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
GSCR2 SUN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SUN2 PI42C â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SUN2 FKB14 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SUN2 AMPM2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SUN2 ACADS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CAV3 SUN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ESR1 DDX3X â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20308691 19805454 21182205 20348541
LMNA DDX3X â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25948554 22412018
SUN2 DHRS4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SKP1 ESR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 23770852
ESR1 SGPL1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33731348 31527615
ESR1 SYNE1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31527615 19805454
FBXL4 SUN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MPPE1 SUN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SUN2 POTEF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EXO1 SUN2 â—¼   KO_DOWN_REGULATES ✅ - -0.83 0.82 PKG 28854368
FBW1B SUN2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 30833792 25515538 19615732 25900982 25332235 28514442
DDB2 CSN7B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SCAR3 SUN2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PI42A PI42C â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 24981860
GOG7B SUN2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ESR1 ACTN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23403292 31527615 19805454 21182205
ESR1 PDIA6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33731348 25604459 31527615
RYBP SKP1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24981860 22325352 27705803
EEF1A1 RPS20 â—¼   PHYSICAL_INTERACTION 836.0 0.83 STRING 36370105
EMD SYNE2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 17462627 34079125
EMD SUN2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19933576 30833792
HGS UBA1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19019082 25260751
LMNA MDC1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 30179224 30419336 22412018
ACTN4 ESR1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25604459 19805454 21078666
ESR1 MYH9 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 25604459 19805454 21182205
BTRC SUN2 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
DDB2 SUN2 â—¼   KO_UP_REGULATES ✅ + 0.86 0.86 PKG 28854368
CUL1 CSN7B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 27833851 29103612 21145461
CGAT2 SYNE4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 25416956 26871637 26186194 28514442
SUN2 RAB5A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 31980649 26496610 21988832 28514442
RAB5C SUN2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 26496610 17353931
BTRC FBXW11 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
RAC3 ESR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21217774 16331275
HGS ACTN4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15772161 22863883 26819309
CDK7 ESR1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10949034 31527615 15461668
ACTN1 TTN â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
FBW1A SUN2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 30833792 19615732 25900982 25332235 28514442 26091241
SYNE1 EMD â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 34079125 17462627 12163176
SYNE1 LMNA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11801724 12163176
SUN2 LMNA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 19933576 30419336 22555292 28514442 34079125
FBW1B CUL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24500709 29103612 18354482 14603323 21145461 19615732 25515538 19150432 25241761 31406304 22851693 25609649 25900982 25332235 10230406 10321728 10644755
FBW1A CUL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 14603323 25900982 25332235 22851693 11850407 15536641 29103612 18056411 25143387 18354482 31406304 21249194 25249620 10644755 31043584 19966869 17215248 17318178 10713156 10023660 15966899 19615732 11483504 10066435 10531035 34703820 28514442 29499133 12609982 19945379 21145461 25515538 27910872 19150432 9990852 29863914
FBW1B FBW1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 19615732 29150431 31406304 25900982 28514442 10644755 16189514
FBW1A SKP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 17463251 31210753 10228155 25900982 25332235 23607312 27705803 30267325 10074433 15536641 15070733 10514433 19061640 19933270 10644755 24912152 25632159 17215248 14706645 31467278 10023660 24469040 9660940 16275325 20596027 11483504 22388891 30254149 30728155 10531035 24811168 25416956 19159283 16189514 28614300 12609982 32350066 26474281 9990852 10918611 29863914 17283138 22632967 12820959 29997244
FBW1B SKP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 26496610 29435596 25900982 25332235 10230406 27705803 15070733 10644755 20596027 19615732 30254149 29150431 10321728 17510365 19159283 24500709 25515538 21145461 32350066 25609649 12165731
FBXL4 SKP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10531037 32877691 33961781 27705803
LMNA SUN2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22555292 16380439 19933576
RAC2 PIK3CA â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 7744773 8645157 11803464
SYNE2 SUN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19933576 22632968 30833792 22555292
NCBP2 SMG1 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
FBXW11 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.92 0.92 mint 25609649
CUL1 BTRC â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 17318178 5219675
SKP1 FBXW11 â—¼   PHYSICAL_INTERACTION ✅ 0.93 0.93 mint 5212166 10644755
COPB1 COPG1 â—¼   CORRELATES + 0.93 0.93 CCLE 31978347
SUN2 SYNE1 â—¼   PHYSICAL_INTERACTION 933.0 0.93 STRING 36370105
SKP1 CUL1 â—¼   PHYSICAL_INTERACTION ✅ 0.95 0.95 mint 7304783 18818696
ACTN1 ACTN4 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
COPB1 COPG1 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
SKP1 BTRC â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 9660940 6547997
RAB5C RAB5A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 17353931 26496610 28514442 34079125
SUN2 SYNE2 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
FBXW11 SKP1 â—¼   PHYSICAL_INTERACTION 969.0 0.96 STRING 36370105
EMD LMNA â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
CUL1 FBXW11 â—¼   PHYSICAL_INTERACTION 975.0 0.97 STRING 36370105
EXO1 ACADS â—¼   KO_DOWN_REGULATES ✅ - -0.98 0.97 PKG 28854368
FTSJ1 WDR6 â—¼   PHYSICAL_INTERACTION 977.0 0.97 STRING 36370105
KPNA2 NCBP2 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
EEF2 RPS20 â—¼   PHYSICAL_INTERACTION 988.0 0.98 STRING 36370105
BTRC CUL1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
BTRC SKP1 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
CUL1 SKP1 â—¼   PHYSICAL_INTERACTION 26.0 1.0 ACSN 11516665 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15668399 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
CUL1 SKP1 â—¼   SHARES_COMPLEX 26.0 1.0 ACSN 11516665 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15489953 15668399 15688063 15703371 16697054 17053147 17884153 18636226 18787170 18931676 19150432 19270156 19622404 19686080 19797085 19809470 19847258
SKP1 CUL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 9663463 19945379 12684064 19270694 16759355 23951410 10648623 11961546 26540345 26976582 26474281 17290223 9736735 21169563 14685242 16357137 21145461 29070679 15452136 15966899 12628165 21778237 22474075 16189514 22767593 11359933 9430629 10713156 10023660 10228155 12504026 18818696 9827542 12504025 18094045 10066435 23324393 23770852 9990852 12417738 27705803 9636170 21249194 12904573 34499862 11027288 26725323 20832730 19933270 12609982 10230407
CDK7 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 30257348 10949034 15461668 9528769 22879364 12118371 28423697 27748765 15059947 16076840 7491495 12093745 23850489 15528270 7838153
FBXW11 SKP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 25609649 10321728 25900982 15070733 12165731 10230406 21145461 26496610 24500709 10023660 10066435 25332235 19615732 19159283 27705803 10644755 25515538
PRKAA1 KPNA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15342649 17919121 27303922
MAPK8 YWHAB â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 7890696 15696159 15071501
RHOC MYH9 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 Reactome 12185584 2966156 8702756 17151359 3839510
SUN2 RAB5A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 21988832 10818110 26496610
MDC1 SUN2 â—¼   KO_DOWN_REGULATES ✅ - -1.16 1.15 PKG 28854368
XRCC4 SUN2 â—¼   KO_DOWN_REGULATES ✅ - -1.22 1.21 PKG 28854368
MDC1 SYNE2 â—¼   KO_DOWN_REGULATES ✅ - -1.34 1.33 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
DDB2 DDB2 â—¼   KO_DOWN_REGULATES ✅ - -5.71 5.7 PKG 28854368
XRCC4 XRCC4 â—¼   KO_DOWN_REGULATES ✅ - -6.32 6.31 PKG 28854368