STK11
|
CDC37
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.8
|
0.8
|
mint
|
34591612
|
GRB10
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
6547677
9506989
|
EGFR
|
IRS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
EGFR
|
NRAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
EGFR
|
KRAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
EGFR
|
HRAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
EGFR
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
17673906
|
GRB10
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
GRB2
|
RPL10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
TGOLN2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
17474147
8109998
|
GRB2
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5216105
12577067
|
GRB2
|
PTPN11
|
â—¼ DEPHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
17993263
15031289
|
NUAK1
|
STK11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
17108107
21317932
|
PTPN11
|
KRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
26617336
|
PTPN11
|
NRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
26617336
|
PTPN11
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
26617336
|
HRAS
|
ERBB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
ERBB2
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17496910
17673906
|
RHOB
|
INSR
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
14722096
6672086
|
ERBB2
|
IRS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
KRAS
|
ERBB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
NRAS
|
ERBB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
23220880
22908275
|
USP11
|
RNF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7998286
20601937
|
EGFR
|
TUBA1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
801.0
|
0.8
|
STRING
|
36370105
|
GRB2
|
MAP4K1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
806.0
|
0.8
|
STRING
|
36370105
|
RIPK4
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
29435596
26972000
|
CDC37
|
ERBB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
25036637
24189400
|
PTPN11
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.82
|
0.82
|
mint
|
16729043
5218694
|
IRS4
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24797263
16273093
|
RHOB
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
RHOB
|
EPHA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
RHOB
|
ROR2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
ILK
|
DNJA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23455922
25852190
|
RHOB
|
MINK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
RHOB
|
MARK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
WDR6
|
IGJ
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RHOB
|
IRS4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
EPHA7
|
EPHA4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RHOB
|
EPHA7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
DMWD
|
WDR6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
RHOB
|
WDR6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
34079125
31871319
|
MEX3B
|
WDR6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
29395067
32460013
|
DNJA2
|
WDR6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
33957083
|
WDR6
|
PAPS2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
WDR6
|
AMY1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
WDR6
|
IGHA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CDC37
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
829.0
|
0.83
|
STRING
|
36370105
|
EGFR
|
EPHA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
24797263
15657067
|
EGFR
|
GRB10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
833.0
|
0.83
|
STRING
|
36370105
|
ERBB2
|
EPHA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
30898150
28628118
28205554
|
ERBB2
|
FGFR4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
30898150
28628118
28205554
|
PTPN11
|
ERBB2
|
â—¼ DEPHOSPHORYLATION
|
✅
|
-
|
0.84
|
0.84
|
Signor
|
32024694
|
KRAS
|
NRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
847.0
|
0.84
|
STRING
|
36370105
|
EPHA7
|
EPHA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
22036564
33961781
|
ERBB2
|
GRB2
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.85
|
0.85
|
Signor
|
14967450
|
IRS4
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
21706016
9553137
|
EPHA7
|
EPHA3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
28514442
22036564
33961781
|
PTPN11
|
EGFR
|
â—¼ DEPHOSPHORYLATION
|
✅
|
-
|
0.86
|
0.86
|
Signor
|
12582165
|
INSR
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
866.0
|
0.86
|
STRING
|
36370105
|
EGFR
|
RAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24658140
25402006
31980649
|
EGFR
|
NTRK2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24658140
25402006
31980649
|
EGFR
|
DNJA2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
24797263
24189400
23956138
15657067
|
ILK
|
RAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
23455922
26496610
25852190
|
RRMJ1
|
WDR6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
26344197
33961781
26496610
|
NRAS
|
RAF1
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.87
|
0.87
|
Signor
|
21779497
|
HRAS
|
NRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
877.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
HSPA8
|
â—¼ PHYSICAL_INTERACTION
|
|
|
878.0
|
0.87
|
STRING
|
36370105
|
RAF1
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
25036637
31980649
24189400
24292678
17979178
33961781
32707033
16611982
16335536
|
GRB10
|
INSR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
EGFR
|
CDC37
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
25036637
31980649
12471035
24189400
23956138
|
NTRK1
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
11733534
25921289
10748052
|
FGFR2
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
24440983
22726438
|
GRB10
|
RAF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9553107
10585452
|
HRAS
|
KRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
893.0
|
0.89
|
STRING
|
36370105
|
FGFR2
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
894.0
|
0.89
|
STRING
|
36370105
|
CDC37
|
STK11
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25036637
14676191
20562859
12489981
21860411
33961781
14668798
32707033
|
NRAS
|
CDC37
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16024644
15118125
15284455
|
KRAS
|
CDC37
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16024644
15118125
15284455
|
HRAS
|
CDC37
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
Reactome
|
16024644
15118125
15284455
|
GRB10
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31980649
24658140
9506989
25402006
9006901
|
EGFR
|
ERBB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
11500850
25241761
30898150
17486068
11526509
9461599
23866081
17426253
10572067
11500516
24557338
8665853
15657067
19060928
16516204
19650109
20211985
25315821
23436906
21278786
25898135
32669362
1346931
24189400
21044682
18803307
16843263
28369073
7531698
16713569
17148612
21203579
17307140
1706616
16207817
7797556
12354693
11408594
|
IRS4
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9553137
15316024
|
MAPK6
|
TUBA1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
MAPK6
|
RPL10
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
21900206
2001699
8089645
|
NR1I2
|
ZFP36
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19129222
|
NR1I2
|
WDR6
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19129222
|
COPS5
|
CUL3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
GRB2
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
16273093
5218056
|
EGFR
|
GRB2
|
â—¼ PHOSPHORYLATION
|
|
|
0.92
|
0.92
|
Signor
|
11726515
|
NRAS
|
RAF1
|
â—¼ PROXIMITY
|
✅
|
|
0.93
|
0.93
|
mint
|
30194290
|
ERBB2
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
939.0
|
0.94
|
STRING
|
36370105
|
EGFR
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
NRAS
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
945.0
|
0.94
|
STRING
|
36370105
|
ERBB2
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.95
|
0.95
|
mint
|
5218411
16516204
|
GRB2
|
PTPN11
|
â—¼ PHYSICAL_INTERACTION
|
|
|
949.0
|
0.95
|
STRING
|
36370105
|
ERBB2
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
957.0
|
0.95
|
STRING
|
36370105
|
EGFR
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
19254954
7518560
31980649
9416834
7592693
23956138
14679214
10085134
7510700
27059931
21706016
25402006
16799092
16729043
8665853
15657067
24797263
12577067
8810325
7650032
11960376
23799367
25187647
8626525
10026169
19289468
18271526
21278786
7506413
17971399
8940013
20124286
11726515
9886492
10595738
24189400
9020117
19531499
20473329
9020193
8662998
8647858
1322798
8887653
10229072
16273093
25754235
31959764
11370743
16713569
21596750
9685397
24658140
31985874
22973453
11896612
20067773
17242169
19836242
8810340
21278788
30544639
7527043
9050991
11408594
8621459
|
ERBB2
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
9710588
11173924
21278786
16713569
9756944
24189400
31980649
22973453
24658140
30898150
16273093
17875712
16729043
11606575
8665853
|
GRB10
|
INSR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
10871840
9369444
12551896
8621530
7479769
9506989
12493740
19648926
9006901
15664450
|
KRAS
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
FTSJ1
|
WDR6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
977.0
|
0.97
|
STRING
|
36370105
|
GRB2
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
16729043
5218694
|
HRAS
|
RAF1
|
â—¼ PROXIMITY
|
✅
|
|
0.98
|
0.98
|
mint
|
18273062
6540139
|
RAF1
|
HRAS
|
â—¼ PROXIMITY
|
✅
|
|
0.98
|
0.98
|
mint
|
18273062
6540139
|
EGFR
|
ERBB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
EGFR
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
EGFR
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
10404636
20430953
23010081
25987127
28513565
|
PTPN11
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
34.0
|
1.0
|
Omnipath
|
28065597
9756944
7588774
16273093
14560030
9642214
8197172
15618223
12270932
7673163
12582165
10411909
16729043
11223155
12577067
|
EGFR
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
109.0
|
1.0
|
Omnipath
|
9544989
10595738
23956138
27059931
10026169
16273093
11726515
24697349
21596750
19289468
7518560
21706016
23799367
9050991
16317285
16713569
25402006
11370743
24797263
8647858
8887653
9416834
21278786
16799092
8662998
10229072
11896612
7592693
19509291
8810325
24189400
19836242
11960376
7506413
18271526
15657067
10085134
24658140
17242169
7510700
8940013
7650032
8810340
11084343
12577067
7527043
31980649
11408594
19531499
20124286
23178716
9886492
23181695
9020117
8479540
14679214
12648464
1322798
17991782
16729043
17971399
|
EGFR
|
ERBB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
65.0
|
1.0
|
Omnipath
|
17081983
16207817
21044682
17148612
24557338
16713569
21203579
10233167
20471394
17389395
17486068
21278786
11500516
11279155
11500850
17426253
16843263
19650109
25241761
24189400
15657067
17307140
18803307
1706616
12354693
10572067
24355130
11408594
19060928
12648464
16516204
15951569
23436906
20211985
|
FGFR4
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
Reactome
|
17505008
18757403
21666749
11689702
11739186
18381441
19809159
21160078
14534538
15448205
|
GRB2
|
KSR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
53.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10843677
10982827
11023813
11034387
11062502
11274345
11385609
11447289
11777939
11907067
12040186
12175651
12419216
12640133
12782630
14585353
14724641
14764585
15169888
15173823
15536084
15547943
15567848
15574420
15735649
15863030
16102570
16227978
16488589
16582911
16887996
17178906
17395718
17496910
17613518
17673906
19289794
19449109
19541618
19565474
19568798
19615955
21102635
22435554
24027568
26552706
7510700
8551221
8929532
9510155
|
GRB2
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
54.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10843677
10982827
11034387
11062502
11385609
11447289
11532940
11777939
11907067
12040186
12175651
12419216
12479806
12566895
12640133
12782630
14585353
14764585
15169888
15516985
15536084
15547943
15567848
15574420
15735649
15863030
16102570
16227978
16488589
16582911
16887996
17178906
17395718
17496910
17673906
18039929
19289794
19449109
19541618
19565474
19568798
19615955
21102635
22435554
24027568
26552706
7510700
8551221
8929532
9069260
9510155
|
GRB2
|
KSR1
|
â—¼ SHARES_COMPLEX
|
|
|
53.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10843677
10982827
11023813
11034387
11062502
11274345
11385609
11447289
11777939
11907067
12040186
12175651
12419216
12640133
12782630
14585353
14724641
14764585
15169888
15173823
15536084
15547943
15567848
15574420
15735649
15863030
16102570
16227978
16488589
16582911
16887996
17178906
17395718
17496910
17613518
17673906
19289794
19449109
19541618
19565474
19568798
19615955
21102635
22435554
24027568
26552706
7510700
8551221
8929532
9510155
|
GRB2
|
RAF1
|
â—¼ SHARES_COMPLEX
|
|
|
54.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10843677
10982827
11034387
11062502
11385609
11447289
11532940
11777939
11907067
12040186
12175651
12419216
12479806
12566895
12640133
12782630
14585353
14764585
15169888
15516985
15536084
15547943
15567848
15574420
15735649
15863030
16102570
16227978
16488589
16582911
16887996
17178906
17395718
17496910
17673906
18039929
19289794
19449109
19541618
19565474
19568798
19615955
21102635
22435554
24027568
26552706
7510700
8551221
8929532
9069260
9510155
|
HRAS
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
KRAS
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
NRAS
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
PTPN11
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
10.0
|
1.0
|
ACSN
|
10358138
11447289
11572860
12138178
12707331
15240681
15699106
15713798
19833085
9751747
|
GRB2
|
KSR1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
53.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10843677
10982827
11023813
11034387
11062502
11274345
11385609
11447289
11777939
11907067
12040186
12175651
12419216
12640133
12782630
14585353
14724641
14764585
15169888
15173823
15536084
15547943
15567848
15574420
15735649
15863030
16102570
16227978
16488589
16582911
16887996
17178906
17395718
17496910
17613518
17673906
19289794
19449109
19541618
19565474
19568798
19615955
21102635
22435554
24027568
26552706
7510700
8551221
8929532
9510155
|
GRB2
|
MAP2K7
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10982827
11274345
11447289
11756498
11777939
12040186
12175651
12640133
12738796
14585353
15567848
15574420
15863030
16102570
16582911
16887996
17496910
17673906
18000759
18855897
19151919
19449109
19568798
21614932
24027568
26552706
27331412
7510700
8551221
|
ERBB2
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
27.0
|
1.0
|
Omnipath
|
31980649
9756944
21278786
16273093
24189400
11173924
9710588
24658140
11606575
14967450
17875712
16713569
16729043
|
FGFR2
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
22726438
19735729
26103942
20554525
23420874
|
NTRK1
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
11733534
10748052
|
PTPN11
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
66.0
|
1.0
|
Omnipath
|
8702859
9361008
16371368
21706016
8041791
11085989
8978300
11432792
15882975
9362449
10212213
11684012
7523381
10592173
16189514
10747947
10973965
9632781
8959326
11602579
12577067
9254654
10080542
15010462
31585087
12531430
8995399
19380743
7522233
9804835
7534299
9824671
9660791
|
GRB2
|
MAP4K1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
9346925
9891069
9788432
17474147
11279207
|
GRB2
|
HRAS
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
17496910
16713569
17673906
11352655
|
STK11
|
NUAK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
14976552
19369195
21317932
20354225
16488889
29566768
|
INSR
|
PTPN11
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
8135823
9832615
7493946
9593725
|
PTPN11
|
ERBB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
9756944
16273093
16729043
32024694
|
STK11
|
MARK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
18.0
|
1.0
|
Omnipath
|
23331499
14976552
19369195
28711359
22238344
17573348
17192257
|
STK11
|
NUAK2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
18083107
14976552
17242355
|
HRAS
|
RAF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
RAF1
|
KSR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
25435214
20179705
20141835
16364920
20130576
15035987
25907612
|
RAF1
|
HRAS
|
â—¼ PHYSICAL_INTERACTION
|
|
|
14.0
|
1.0
|
ACSN
|
10358164
11532940
12566895
14764585
15516985
16102570
19289794
19565474
24027568
7510700
8551221
9069260
9763606
9846483
|
RAF1
|
HRAS
|
â—¼ SHARES_COMPLEX
|
|
|
14.0
|
1.0
|
ACSN
|
10358164
11532940
12566895
14764585
15516985
16102570
19289794
19565474
24027568
7510700
8551221
9069260
9763606
9846483
|
RAF1
|
HRAS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
14.0
|
1.0
|
ACSN
|
10358164
11532940
12566895
14764585
15516985
16102570
19289794
19565474
24027568
7510700
8551221
9069260
9763606
9846483
|
KRAS
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
53.0
|
1.0
|
Omnipath
|
10958680
12750173
9516156
12932319
9665134
10783161
8805624
1386920
1639773
8340422
8601312
19595761
23331499
16041367
21071413
8332195
9446616
10882715
25852190
10531446
1996324
19029954
8503013
16093354
19541618
23153539
16293107
1708096
19933846
26721396
11136732
10205168
20802526
31980649
7760835
18775988
8307946
12917261
11134016
20080631
8180183
1990291
|
KSR1
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
7477354
12932319
9665134
9094715
19766101
23331499
8601312
19595761
11478855
8332195
15520859
8503013
16093354
19541618
19933846
10205168
7760835
18775988
18789263
11134016
8180183
1990291
|
KSR2
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
12975377
23331499
|
HRAS
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
147.0
|
1.0
|
Omnipath
|
17145710
18273062
9523700
1639773
8601312
19595761
20133694
11032808
9154803
10882715
14654780
1996324
19222999
16301319
11948414
8530446
7969158
11313862
9150145
20080631
1990291
12750173
15031288
12932319
9665134
8805624
8340422
1386920
23331499
16916524
16041367
23180781
18988627
20178605
15688026
15664191
22169110
11733498
7862125
8180183
19063885
12391160
9144171
8035810
9020159
14724584
19696784
21779497
9261098
12173045
12620389
8628317
19914712
1708096
19933846
26721396
7730360
10205168
8332187
16803888
18775988
12917261
9099670
10545207
25684575
8670882
10783161
12379659
10887184
17569879
21071413
8332195
7523381
10531446
24929361
8503013
16093354
19541618
10369681
8911690
18073111
11136732
10922060
7760835
11134016
|
NRAS
|
RAF1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
46.0
|
1.0
|
Omnipath
|
9867809
12750173
12932319
9001246
9665134
8805624
1386920
1639773
8340422
8601312
19595761
23331499
21071413
8332195
10531446
10882715
7811320
1996324
18988627
21779497
8636091
8503013
7766599
16093354
19541618
8180183
1708096
19933846
32296183
9525741
8876196
11136732
10205168
21478863
7760835
18775988
12917261
11134016
18641128
20080631
9488663
1990291
|
HRAS
|
KSR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
HRAS
|
FGFR4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
KRAS
|
KSR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
NRAS
|
KSR1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
6.0
|
1.0
|
Reactome
|
15035987
21779496
24957944
22510884
23352452
25907612
|
INSR
|
GRB10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
9506989
15664450
10871840
8621530
9006901
19648926
7479769
12783867
12493740
|
KRAS
|
FGFR4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|
NRAS
|
FGFR4
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
11.0
|
1.0
|
Reactome
|
19946327
11429702
11157491
18757403
21666749
21711248
18381441
19103595
21160078
9857065
20179196
|