Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MESD SYNE2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ARRB2 MDM2 â—¼   UBIQUITINATION ✅ 2.0 0.8 intact 5214648 11588219
HSPA5 BCAR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
SYNE2 COL23A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA5 SYNE2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
MAPK3 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19046355 9614189
PML MDM2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216620 12915590
MDM2 PML â—¼   COLOCALIZATION 2.0 0.8 intact 5216620 12915590
S100A4 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20591429
NPM1 SYNE2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PML STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12506013 16189514
PRKDC SYNE2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
RPL7A SYNE2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SYNE2 STXBP3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ERCC6 SYNE2 â—¼   KO_DOWN_REGULATES ✅ - -0.82 0.81 PKG 28854368
BAP31 SYNE2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 34079125
BAP31 VAPA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 34079125 31588230
CE170 SYNE2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
NDEL1 CE170 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17043677 31413325
CAN6 SUN1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CAN6 SYNE2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CDC5L EXOC1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17043677 31413325
EMD VAPB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25910212 34079125
MDC1 MDM2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18471438 14578343
VAPA SYNE2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VAPB SYNE2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CDC5L DISC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17043677 31413325 90000000
EXOC1 DISC1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17043677 31413325 90000000
EMD SUN1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24375709 34079125
MDM2 NPM1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
EMD SYNE2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 17462627 34079125
EMD SUN2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19933576 30833792
SYNE2 ACTC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12118075 12408964
MDM2 PML â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
DISC1 NDEL1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
VAPA VAPB â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
CDC5L PRKDC â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11101529 20467437
STAT3 PML â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16189514 12506013
ARRB2 MDM2 â—¼   PHYSICAL_INTERACTION 884.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
MAPK1 STAT3 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
CE170 DISC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29961565 33961781 17043677 31413325 90000000
TNIK DISC1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29961565 17043677 31413325 90000000 32707033
MAPK3 ABI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21419341
MDM2 ARRB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 18544533 21389118 21081496 33649538 32828283 17984062 32450252 12538596 21988832 15878855 26545496 12488444 21466165 11588219
MAPK3 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15093545
MAPK8IP2 SYNE2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRKDC MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17570479 22444248 10721693
SYNE2 SUN2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19933576 22632968 30833792 22555292
MDM2 USP7 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
SUN2 SYNE2 â—¼   PHYSICAL_INTERACTION 961.0 0.96 STRING 36370105
NDEL1 DISC1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 29961565 33961781 32296183 17043677 31413325 20880836 90000000 12506198 14962739 28514442 12812986
USP7 MDM2 â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 6799761 18566590
MAPK1 ABI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19917258 17855441 21419341 21900237
DISC1 NDEL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 17145710 12812986 17043677 12506198 31413325 20880836 29961565 14962739 17202468
NPM1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 31434245 22955283 12748172 16009132
MAPK1 MAPT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 67.0 1.0 Omnipath 9614189 9832145 12387894 12766916 12765608 12414518 19413330 1330687 24116116 19415658 15302935 33961674 9716264 34493616 31178717 28066266 15324364 31065832 25573097 12801934 29298849 16165272 15883264 16115884 8166686 33952699 9565682 11181841 34536819 10737616 7566346 18315566 9771888 29760653 34480088 24301651 15542598 18055457 12226093 7488031 9199504 18510355 21731772
MAPK1 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 22935031 29416846 23293771 23316480 15093545
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 59.0 1.0 Omnipath 18448488 19413330 11335711 9343414 15465816 25584415 12576423 11350938 20068231 12681450 12763138 9872331 11780390 18491316 18669648 11404481 10521505 18691976 20058876 15979846 14551213 10446219
MAPK3 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 73.0 1.0 Omnipath 18448488 19413330 11335711 9343414 23331499 15465816 25584415 12576423 11350938 20068231 12681450 10417333 12763138 9872331 18988627 11780390 18491316 18669648 11404481 10521505 18691976 19723038 20058876 14551213 10446219
USP7 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17145710 17936559 26460617 15916963 24462112 22056774 18566590 20816748 16402859 20713061 16943424 17380154 29236775 16082221 26238070 34799561 16845383 16474402 28406480 27452404 28196907
MDM2 PML â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15195100 12759344 14507915 16713569 12915590
MDC1 BCAR1 â—¼   KO_UP_REGULATES ✅ + 1.01 1.01 PKG 28854368
MDC1 TERF2 â—¼   KO_DOWN_REGULATES ✅ - -1.08 1.07 PKG 28854368
MDC1 SUN2 â—¼   KO_DOWN_REGULATES ✅ - -1.16 1.15 PKG 28854368
ERCC6 ERCC6 â—¼   KO_DOWN_REGULATES ✅ - -1.24 1.23 PKG 28854368
MDC1 SYNE2 â—¼   KO_DOWN_REGULATES ✅ - -1.34 1.33 PKG 28854368
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368