Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NLGN3 AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 3002166 21653829
ERBB3 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17496910 17308105
CBL ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17635922 10514377
IRS1 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
EGFR IRS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
GRB2 ERBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16729043 5218694
LCK GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
IRS1 IRS4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11912194
IRS4 P85B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 25036637
RN19B P85B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FLRT1 P85B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CL059 P85B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HAVR2 P85B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RASK P85B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21988832 34079125
MANS1 P85B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
I20RA P85A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FLRT1 P85A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DEF5 P85A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RN19B P85A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
P55G P85A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FAK1 PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22402981 10733346
FLRT1 P55G â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HAVR2 P55G â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CL059 P55G â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
IRS4 P55G â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 25036637
NLGN3 P55G â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SQSTM PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27684187 18624398
I20RA PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RN19B PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FLRT1 PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ZDHC1 PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SUN2 PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
DEF5 PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NLGN3 PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
MANS1 PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CL059 PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HAVR2 PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
EFNB2 PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
IRS4 EGFR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16273093 24797263
P85B P85A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 32203420 26186194 28514442 19380743
P85B P55G â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 19380743 26186194
EFNB2 P85B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PCBP1 P85A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PK3CA PTN11 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 9565634 26839216 9660791
RASK EGFR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30194290 12783862 30639242 34079125
IRS4 PK3CA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 11912194
PCBP1 PK3CA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
GRB2 PK3CA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 21706016 9565634 32814053 28514442 19380743
P85B IRS1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11120660 30240640 12730242 23604317 7559478
IRS4 P85A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 25036637 18165436 11912194
PTN11 CBL â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 18519587 17330819 11157475
PK3CA AKT1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19117013 21041639 25793261 21816939
HAVR2 LCK â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 26492563 22863785
AKT1 IRS1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 10497255 17640984
RHES PK3CA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 14724584 16757351
PK3CA RASN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 8665852 7820549 30639242
CBL PK3CA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9119889 8641358 19380743 11157475
AKT1 P85A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16007092 19117013 10527852 28205554 28628118
GRB2 P55G â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 32296183 21706016
SQSTM LCK â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 8650207 16189514
PK3CA EGFR â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31959764 25754235 8561895 28628118 28205554 1845983
IRS4 GRB2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9553137 21706016
FAK1 P55G â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25814554 22402981 32296183
ERBB3 PK3CA â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11546794 24189400 19411071
FAK1 P85A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11119718 10973983 10806474 8649427 16713569 7537275 19889638 11104793
HAVR2 P85A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 26492563
FAK1 PTN11 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10082579 7589239 10655584 20473329 8986614 21726809 16189514
P55G IRS1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10417350 25814554 9415396 7542745
P55G ERBB3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 22973453 16273093 24189400
RASK PK3CA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 34079125 10783161
CBL LCK â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
P85B GRB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20936779 8662998 19380743 21706016
P85B PK3CA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14681455 22402981 25253337 26496610 27684187 23604317 19380743
LCK P85A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8246987 7504174 9461588 8294442 34079125
PTN11 P85A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9918857 11593409 10962556 9361008 9660791 26839216 8647120 9632795 9565634 9886492 16371368
P55G EGFR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24658140 31980649 22973453 25241761 25402006 16273093
IRS1 PK3CA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12933652 27684187 23643389 23604317 16354680 16150444 14511371
PK3CA LCK â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 8246987 8020561 14583609
EGFR AKT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
CBL EGFR â—¼   UBIQUITINATION ✅ - 0.89 0.89 Signor 20332299
EGFR CBL â—¼   RELOCALIZATION ✅ + 0.89 0.89 Signor 16829981
ERBB3 P85B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16273093 16729043 22973453 24189400
EGFR P85B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19531499 31959764 24658140 31980649 22973453 23956138 11172806 1334406 25402006 16273093
CBL P85A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9918857 19190244 17237826 7544353 10358153 8662998 9259313 8621719 14530346 15581361 7642581 15556646 9890943 16219545 10918571 8995243 16135792 9414268 8702998 8612729 19861161 16713569 11157475 19380743 11042121 16289966 9234717 16982329 8896416 9178909 33512474 8941725 11944898 25814554 9541596 9890970 9461587 9160881 7791764 9174058 8695807 24113870 11133830 11087752 18374639 9092538 10025673 9988765 11418612 15107835 21203488 11994282 10620516 11030146
RASH P85A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10212255 9150145 25241761 16713569
P85A EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19531499 21701776 7531698 31959764 22973453 8662998 25241761 16230374 7797556 25754235 25187647 16713569 7499252 16273093
PTN11 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12270932 11223155 20473329 16729043 22973453 7673163 28065597 24935154 9756944 14560030 7588774 8959326 16273093
FAK1 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15657067 24658140 31980649 20473329 10806474 25402006 16713569
EGFR CBL â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23158001 24797263 25872741 31182136 10635327 26055326 14505571 15210722 32714745 23774213 19155296 11370743 19836242 8665853 19947936 18271526 25140053 15668240 22394513 17486068 33323455 32377695 22203672 17182860 12604776 14627991 15383614 23153581 15735736 28541302 16849543 17242169 20562913 32904620 9121472 15677445 7782294 16923119 17995934 19531499 15465819 31959764 32114396 23457600 29629558 18316398 23799367 24714105 31120930 12061819 16713569 7657591 33617900 10086340 19225046 33762435 23175185 16729043 28791635 16246327 28198003 15962011 22266821 15117950 27059931 10428778 12734385 8662998 25005938 27903975 16969069 26177020 8798643 10799548 9756944 15159412 19578043 15657067 18255265 23418353 25754235 22976291 17545148 12803489 18319245 19713535 7592693 30544639 15107835 11994282 17971399 16105874 15282549 20940296 23897813 9130710 18273061 18508924 17880946 20124286 12593795 16914641 20877636 10092522 25521828 11408594 22591401 9890970 20308550 22833562 21772844 33627783 11239464
IRS1 CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10854852 19546233
ERBB3 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23436906 10527633 27756321 21278786 18803307 17148612 22439932 25315821 10572067 24189400 23866081
IRS4 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9553137 15316024
GRB2 IRS1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
GRB2 CBL â—¼   RELOCALIZATION ✅ + 0.91 0.91 Signor 11823423
ERBB3 PTN11 â—¼   PHYSICAL_INTERACTION 0.92 0.92 HIPPIE 22973453 9756944 28065597
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
ERBB3 GRB2 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
RASH PK3CA â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 24412244 9150145 10783161 14724584 8665852
P85B CBL â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 19190244 11133830 15107835 25814554 19380743 7629144
P55G PK3CA â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 14681455 33961781 22402981 26496610 9415396 28514442 25814554
CBL EGFR â—¼   COLOCALIZATION ✅ 0.96 0.96 mint 16914641 7033849 028274
ERBB3 P85A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 15812817 11546794 20227043 21278786 11389077 22973453 10383151 9130710 24189400 21075308 9756944 12896906 18803287 22439932 11694521 10572067 16273093 20007781
P85A GRB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 7544353 8621719 18346204 7642581 16219545 32814053 7642542 20936779 16713569 19380743 21706016 7759531 8647120 25416956 9541596 9174058 11418612 7737969 9886492
P85A PK3CA â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22402981 20018188 26496610 23643389 26475863 26839216 11526404 16135792 32814053 27684187 7957566 15932879 28628118 16043515 20713702 15377662 9235916 25253337 19805105 19574958 33420362 7929193 24657164 19117013 28205554 9565634 18079394
PTN11 GRB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 8702859 33961781 12531430 34407391 10747947 9824671 12577067 9361008 9660791 19380743 7534299 8995399 16371368 10080542 21706016 20473329 7523381 8041791 9362449 10212213 8647120 28514442 16189514 9632781 31980649 9254654 8959326
FAK1 GRB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10085298 7597091 20473329 7997267 10806474 21900206 8649427 12558988 12005431 16713569 8816475 16189514
IRS1 GRB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 8810325 21706016 7486683 8536716 8388384 8491186 22974441 12173038 7488107 7629070
EGFR ERBB3 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
P85A IRS1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 8382612 8175658 7680095 17640984 23643389 16230374 26839216 7659087 9564850 14511371 12220227 7486683 1381348 15514089 22974441 12730242 16043515 16150444 16354680 16880210 12107746 30240640 33991522 19561084 8628286 14632132 25814554 7935461 7680644 8388384 29526746 11416002 1334490 23439647 12173038 25273559 11403293
PTN11 IRS1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 11781100 8505282 7935386 9535915 22974441 9756938 7513703
CBL EGFR â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
CBL GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
AKT1 IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 17570479 17640984 10497255
GRB2 CBL â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 25036637 25872741 8950973 917890 7642581 17944804 15210722 9108392 20936779 8695851 19836242 14725908 169092 28514442 9541596 9174058 11823423 12941616 10829062 10570290 7544353 11792427 8083187 15677445 8621719 9233773 9311917 23799367 16713569 10086340 9234717 8995358 25814554 9716598 11997436 7791764 8943292 8063801 8995445 8662998 11263968 16906159 8626404 9129019 98621719 17072306 9242692 10521482 9872323 8647120 7592693 9092538 10025673 17971399 17094785 9851874 11399323 33961781 9259313 18273061 7537740 8649804 9295052 11964172 9367879 20124286 10204582 19380743 9434624 21706016 8900205 9178909 12839496 9461587 31980649 11133830 33627783 8824292 8621483
GRB2 CBL â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
LCK CBL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 9525940 10829062 10799548 10934191 7721825 16107303 12604776 9890970 17570479 11904433 9178909 10092522 11997497 12522270 8621719 9102067 11239464 11994282 11741956
CBL EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 188.0 1.0 Omnipath 34609770 16105874 18273061 22239438 24797263 20332299 17635922 23158001 17545148 8662998 12604776 9890970 23153581 17182860 25872741 12593795 23175185 10092522 15107835 22266821 22833562 24714105 17242169 25140053 20124286 19531499 9756944 10086340 22203672 19225046 16729043 15282549 20562913 22394513 20940296 23331499 7592693 19713535 10635327 19836242 15465819 15210722 25521828 23897813 10514377 12734385 18508924 11994282 20877636 33323455 22976291 23774213 23027125 15159412 18255265 16246327 28541302 16849543 23799367 16713569 10799548 8798643 19155296 9121472 17486068 21772844 16969069 15677445 15962011 23418353 12803489 32714745 14505571 27903975 19578043 26177020 11239464 18319245 11408594 10428778 12061819 17995934 17971399 27059931 26055326 15735736 23457600 7782294 22591401 29629558 11370743 7657591 21071413 28198003 18316398 19947936 9130710 18271526 15657067 31182136 16923119 17880946 32904620 15117950 14627991 15668240 15383614
CBL GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 158.0 1.0 Omnipath 11823423 8621483 9242692 18273061 17635922 16906159 8626404 8662998 9108392 9541596 98621719 9295052 25872741 17372273 8824292 8943292 12941616 20124286 19531499 10086340 8063801 9129019 9590251 11263968 9461587 7642581 10521482 10204582 8995445 8900205 7592693 9716598 8083187 14725908 17904548 7791764 9178909 25036637 8695851 19836242 7537740 15210722 9108316 169092 9311917 10514377 9092538 17072306 19380743 9872323 9234717 11997436 23799367 9434624 16713569 10829062 9367879 11964172 12839496 15677445 9851874 11792427 17094785 20936779 10570290 917890 17944804 25814554 17971399 11133830 8950973 21706016 8995358 9233773 10025673 8621719 11399323 9259313 9174058 8649804
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 23436906 7929151 21278786 24189400 23866081 17148612 12648464 27756321 18803307 10527633 10572067 22439932
ERBB3 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 9756944 24189400 11173924 24658140 14967450 16729043
IRS1 GRB2 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10086337 10826997 12175651 12444011 12767520 16931767 17604717 19030972 21540285 22465479 24036369 8621421
LCK GRB2 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10652356 11062502 12731048 12740575 15536084 17544292 19290918 20814939 21127503 22513334 23620508 8478617 8986721 9438848 9738502 9751747
IRS1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 8265614 7862167 11788580 8388384 8491186 8536716 7488107 7486683 10358772 10592173 8196603 12173038 12679424 8114695 11259577 8810325