IRS1
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
EGFR
|
IRS4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
GRB2
|
ERBB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16729043
5218694
|
ERBB3
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
SRC
|
ERBB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218056
16273093
|
IRS1
|
IRS4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
11912194
|
IRS2
|
IGF1R
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
8662806
5221055
|
CRK
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
803.0
|
0.8
|
STRING
|
36370105
|
IRS4
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
24797263
16273093
|
EGFR
|
IGF1R
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
17047074
17307140
|
P55G
|
NISCH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
HAVR2
|
NISCH
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
NISCH
|
P85A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
32203420
27173435
|
CRK
|
PK3CB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
31980649
19380743
|
SRC
|
P55G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22402981
25814554
|
CL059
|
P85B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
IRS4
|
P85B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
25036637
|
FLRT1
|
P85B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
HAVR2
|
P85B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
P55G
|
P85A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
FLRT1
|
P85A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
FAK1
|
PK3CA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
22402981
10733346
|
HAVR2
|
PK3CB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
FLRT1
|
PK3CB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
NLGN3
|
PK3CB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CL059
|
PK3CB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
IRS4
|
P55G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
33961781
25036637
|
HAVR2
|
P55G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
AL3B1
|
P55G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CL059
|
P55G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
NLGN3
|
P55G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
P55G
|
EHD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
FLRT1
|
P55G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
HAVR2
|
PK3CA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
FLRT1
|
PK3CA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
CL059
|
PK3CA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
NLGN3
|
PK3CA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
GRB2
|
PK3CA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
9565634
21706016
32814053
33961781
19380743
|
GRB2
|
PK3CB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
21706016
|
SOCS6
|
IRS4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
12052866
28883622
|
SOCS6
|
P55G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
26186194
25814554
|
P85B
|
P85A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
19380743
32203420
|
P85B
|
P55G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
26186194
33961781
19380743
|
TGFR2
|
PK3CB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
IRS4
|
PK3CA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
33961781
11912194
|
TGFR2
|
P55G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
GRB2
|
IRS2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
7559579
22974441
9852124
21706016
|
CRK
|
SRC
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
23397142
10962563
12615911
|
P85B
|
IRS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
7559478
30240640
11120660
23604317
12730242
|
IRS4
|
P85A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.84
|
0.84
|
HIPPIE
|
33961781
25036637
18165436
11912194
|
SRC
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
16189514
16713569
11964172
9016807
12624098
|
IGF1R
|
IRS1
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.85
|
0.85
|
Signor
|
17827393
|
PK3CA
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
28628118
25754235
1845983
8561895
28205554
31959764
|
IRS4
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
21706016
9553137
|
GRB2
|
P55G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
32296183
21706016
|
CRK
|
P55G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
19380743
25814554
|
P85A
|
IGF1R
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
8603569
25241761
7642582
8697095
7589433
|
ERBB3
|
PK3CA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
11546794
19411071
24189400
|
FAK1
|
P55G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
22402981
32296183
25814554
|
PK3CD
|
P55G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
28514442
32296183
33961781
|
CRK
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
EGFR
|
SOCS6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
22973453
24658140
25402006
31980649
|
NISCH
|
IRS4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
25036637
11912194
|
CRK
|
P85A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
25241761
11418612
10962563
12878163
25814554
19380743
|
IGF1R
|
IRS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
7559507
8776723
10082579
7541045
8530377
33991522
8895367
12220227
15629149
8662806
|
P55G
|
IRS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
9415396
10417350
25814554
7542745
|
IRS2
|
P55G
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
33961781
10417350
|
P55G
|
ERBB3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
22973453
16273093
24189400
|
TGFR2
|
P85B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
33961781
9435577
26186194
|
P85B
|
PK3CD
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
9113989
19380743
|
FAK1
|
P85A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
16713569
19889638
10806474
7537275
11104793
10973983
8649427
11119718
|
HAVR2
|
P85A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
33961781
26492563
|
P85A
|
TGFR2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
28514442
33961781
9435577
26186194
|
P55G
|
RB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
12588990
16189514
|
CRK
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
P55G
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
25241761
31980649
22973453
24658140
16273093
25402006
|
ERBB3
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9756944
24189400
24658140
16729043
11173924
|
P85B
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
19380743
21706016
8662998
20936779
|
P85B
|
CRK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
31980649
19380743
25814554
|
SRC
|
P85A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12210743
25241761
16713569
23065768
12393736
24498420
7499252
10487518
32814053
16230374
23397142
19861161
19903481
|
IRS1
|
PK3CA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
16150444
12933652
23643389
16354680
27684187
23604317
14511371
|
P85B
|
PK3CB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
28514442
22402981
33961781
26186194
19380743
32707033
|
P85B
|
PK3CA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
22402981
26496610
25253337
14681455
19380743
27684187
23604317
|
SRC
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.9
|
0.9
|
mint
|
17284441
6169640
|
ERBB3
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21278786
24189400
27756321
18803307
17148612
25315821
22439932
10527633
23436906
23866081
10572067
|
P85A
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
21701776
25241761
16713569
7499252
19531499
22973453
25187647
8662998
16273093
25754235
7797556
31959764
16230374
7531698
|
FAK1
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31980649
16713569
24658140
20473329
10806474
25402006
15657067
|
EGFR
|
CRK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16729043
9642287
31980649
10595738
22973453
24658140
11956190
16273093
9617486
25402006
12198159
8875975
9480911
|
EGFR
|
P85B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
31980649
23956138
11172806
19531499
24658140
22973453
16273093
25402006
1334406
31959764
|
IRS2
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
3.0
|
0.9
|
ACSN
|
19109239
7890616
9535722
|
IRS4
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9553137
15316024
|
IRS4
|
CRK
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9614078
11316748
16713569
|
CRK
|
FAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
10085298
7561682
7529876
7509446
11314030
12615911
25814554
12370821
|
P55G
|
IGF1R
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
17360667
9415396
25241761
9524259
|
IRS2
|
P85A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
9334184
12107746
15514089
12506011
26496610
11438664
8910607
23439647
19561084
9852124
21241768
|
ERBB3
|
P85B
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
16729043
22973453
16273093
24189400
|
GRB2
|
IRS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
912.0
|
0.91
|
STRING
|
36370105
|
ERBB3
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.92
|
0.92
|
mint
|
31862538
|
EGFR
|
GRB2
|
â—¼ PHOSPHORYLATION
|
|
|
0.92
|
0.92
|
Signor
|
11726515
|
EGFR
|
SRC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
932.0
|
0.93
|
STRING
|
36370105
|
ERBB3
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
948.0
|
0.94
|
STRING
|
36370105
|
P55G
|
PK3CB
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
22402981
33961781
25814554
|
P55G
|
PK3CA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
28514442
22402981
9415396
26496610
14681455
33961781
25814554
|
SRC
|
EGFR
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
31980649
8845374
21573184
25402006
7506422
10075741
19704002
10971656
23175185
10777553
22227249
20935677
20624308
21268077
17158602
24189400
9020193
16713569
22973453
11983694
24658140
28065597
21278788
17284441
7797556
20333651
7527393
10358079
|
EGFR
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
19254954
7518560
31980649
9416834
7592693
23956138
14679214
10085134
7510700
27059931
21706016
25402006
16799092
16729043
8665853
15657067
24797263
12577067
8810325
7650032
11960376
23799367
25187647
8626525
10026169
19289468
18271526
21278786
7506413
17971399
8940013
20124286
11726515
9886492
10595738
24189400
9020117
19531499
20473329
9020193
8662998
8647858
1322798
8887653
10229072
16273093
25754235
31959764
11370743
16713569
21596750
9685397
24658140
31985874
22973453
11896612
20067773
17242169
19836242
8810340
21278788
30544639
7527043
9050991
11408594
8621459
|
FAK1
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
10085298
21900206
16189514
16713569
7597091
20473329
10806474
8816475
8649427
12558988
12005431
7997267
|
IRS1
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
7488107
8388384
7486683
8810325
22974441
21706016
8491186
7629070
12173038
8536716
|
P85A
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
25416956
9174058
11418612
21706016
7544353
18346204
7737969
9886492
16219545
19380743
7642581
7759531
16713569
8621719
7642542
9541596
8647120
32814053
20936779
|
CRK
|
GRB2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
8810325
10962563
8662907
19380743
10970810
|
SRC
|
FAK1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
11980671
16189514
25241761
23242524
17525734
25814554
12615911
16291744
21034468
10931187
21855630
23065768
9507031
12387730
8816475
11119718
8941336
8054685
15987550
26264872
7529876
11104793
16966330
9822703
7997267
10085298
16713569
22402981
32814053
12558988
11927607
|
ERBB3
|
P85A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
12896906
21278786
9756944
24189400
22973453
18803287
11389077
10383151
22439932
11694521
16273093
21075308
20007781
9130710
10572067
11546794
20227043
15812817
|
PK3CB
|
P85A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
10358930
25241761
20713702
24657164
26839216
26496610
32814053
21825134
33961781
27107012
32707033
22939629
8139559
26344197
|
PK3CD
|
P85A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
22020336
31031754
32296183
24165795
9113989
21827948
26496610
18641334
|
P85A
|
PK3CA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.97
|
0.97
|
HIPPIE
|
19805105
26839216
9565634
19117013
27684187
9235916
18079394
23643389
26496610
7957566
28205554
26475863
15377662
11526404
20018188
24657164
25253337
15932879
19574958
16135792
28628118
22402981
20713702
33420362
32814053
7929193
16043515
|
EGFR
|
ERBB3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
973.0
|
0.97
|
STRING
|
36370105
|
GRB2
|
EGFR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
16729043
5218694
|
IGF1R
|
IRS1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
P85A
|
IRS1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
29526746
16150444
14632132
22974441
8628286
26839216
8382612
7680095
33991522
25814554
16880210
19561084
16230374
8175658
7659087
8388384
1381348
23643389
23439647
7935461
12107746
11403293
15514089
7680644
12173038
25273559
14511371
12730242
11416002
7486683
17640984
1334490
30240640
16354680
12220227
9564850
16043515
|
EGFR
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
EGFR
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
5.0
|
1.0
|
ACSN
|
10404636
20430953
23010081
25987127
28513565
|
SRC
|
EGFR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
232.0
|
1.0
|
Omnipath
|
16414009
17081983
25958313
16943190
15618223
19935697
19305428
25402006
24797263
29285309
7488034
15592458
17389395
16461772
20562096
19275932
17897439
15899872
17570479
2803273
23636329
23246962
25505586
23175185
15615697
23349873
16849545
25356505
11983694
24189400
11756413
25748412
26325669
26150526
14512423
18789131
14750954
31978707
25573954
27495374
20071362
18707149
28759036
16729043
26494466
27716204
25537504
17237269
18687633
25884760
29036202
26936397
17575160
20926745
20935677
15282306
23702846
15476828
9069259
19336574
20421302
15660394
23866081
19377510
9777370
22426783
29321659
33706413
25841779
19840943
18669648
12397069
16843263
18957516
34088769
25077442
14963038
19836242
17653080
19625610
16936701
11960379
15548697
18295415
17523611
21268077
20333651
21399647
23376850
11250711
23942551
19704002
22927910
11160627
31952541
10777553
17016520
2543678
19258037
33883672
17646646
28102297
23873690
26771606
21573184
23119029
19151764
16713569
7797556
25955608
15302935
20407013
28513565
23119185
9990038
21080693
20190765
25347738
14630916
15708852
21822308
20628053
25301722
24658140
19690143
27564112
20802523
29124875
33657368
12101233
21787862
14764607
17284441
12878163
26290602
15951569
16543144
15212693
17971399
14523024
10971656
21278788
8845374
22430206
18083107
29641465
18234969
18460189
17551925
22957061
26571308
17043637
20371672
10358079
16799092
19154417
23066441
28065597
12842895
18180459
17158602
18271526
15657067
25159151
34367939
24919575
10075741
25366117
24349301
17561374
16862179
20215522
31980649
24335899
16037379
18451158
14530278
16505275
12063263
23449029
11311660
|
EGFR
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
109.0
|
1.0
|
Omnipath
|
9544989
10595738
23956138
27059931
10026169
16273093
11726515
24697349
21596750
19289468
7518560
21706016
23799367
9050991
16317285
16713569
25402006
11370743
24797263
8647858
8887653
9416834
21278786
16799092
8662998
10229072
11896612
7592693
19509291
8810325
24189400
19836242
11960376
7506413
18271526
15657067
10085134
24658140
17242169
7510700
8940013
7650032
8810340
11084343
12577067
7527043
31980649
11408594
19531499
20124286
23178716
9886492
23181695
9020117
8479540
14679214
12648464
1322798
17991782
16729043
17971399
|
EGFR
|
ERBB3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
17145710
23436906
7929151
21278786
24189400
23866081
17148612
12648464
27756321
18803307
10527633
10572067
22439932
|
EGFR
|
CRK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
52.0
|
1.0
|
Omnipath
|
10595738
9480991
16273093
9617486
25402006
17399949
8662907
8875975
21602891
20068231
8194526
12198159
9642287
11956190
24658140
26656091
9480911
31980649
15212693
26473374
16729043
17016520
|
IRS1
|
GRB2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
7.0
|
1.0
|
Reactome
|
8316835
8810325
9832424
8621421
8530377
9852124
9003010
|
GRB2
|
CRK
|
â—¼ PHYSICAL_INTERACTION
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
GRB2
|
CRK
|
â—¼ SHARES_COMPLEX
|
|
|
32.0
|
1.0
|
ACSN
|
10086337
10567412
10811803
10849428
10982827
11335727
11447289
11449354
11532940
11777939
12175651
12393695
12640133
15308668
15567848
15574420
16000375
16076871
16530705
16582911
16887996
17496910
17673906
18835194
19449109
19454690
22064427
22464172
24217602
25922287
26552706
8551221
|
IRS1
|
GRB2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
12.0
|
1.0
|
ACSN
|
10086337
10826997
12175651
12444011
12767520
16931767
17604717
19030972
21540285
22465479
24036369
8621421
|
ERBB3
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
9756944
24189400
11173924
24658140
14967450
16729043
|
IRS1
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
8265614
7862167
11788580
8388384
8491186
8536716
7488107
7486683
10358772
10592173
8196603
12173038
12679424
8114695
11259577
8810325
|
IRS2
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
7559579
11788580
10358772
11305324
9852124
|
SRC
|
GRB2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
12624098
11964172
9016807
16713569
26103942
20554525
|
IRS1
|
CRK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
9837978
8810325
8621590
|
IGF1R
|
CRK
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
30.0
|
1.0
|
Omnipath
|
17145710
12198159
9642287
9480991
9480911
20068231
11956190
8194526
8875975
15522217
17016520
|
SRC
|
IGF1R
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
17389395
15212693
18691976
7559478
7493944
7537849
20068231
23472139
8550552
17016520
8940173
9480911
|
IGF1R
|
IRS1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
15.0
|
1.0
|
ACSN
|
10086337
10826997
11274345
12175651
12444011
12556535
12655147
12767520
16931767
17145802
17673906
19030972
21540285
24103846
24782617
|
IGF1R
|
IRS1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
44.0
|
1.0
|
Omnipath
|
7541045
12444011
19030972
10082579
16931767
21798082
12220227
11259577
12767520
10826997
23331499
17827393
7504175
21071413
7559507
11572799
27856640
12175651
17570479
15829723
18988627
15629149
11557037
20670944
8530377
21540285
8776723
25886138
8662806
|
IGF1R
|
IRS4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
9553137
18988627
11316748
|
IGF1R
|
IRS2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
23331499
8662806
9852124
10471495
|