Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ERBB3 CRK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
IRS1 EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
EGFR IRS4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
GRB2 ERBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16729043 5218694
SRC ERBB3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
IRS2 IGF1R â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8662806 5221055
IRS1 IRS4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 11912194
CRK GRB2 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
IRS4 P85B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 25036637
FLRT1 P85B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CL059 P85B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HAVR2 P85B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FLRT1 P85A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NISCH P85A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27173435 32203420
P55G P85A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FAK1 PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22402981 10733346
CL059 PK3CB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HAVR2 PK3CB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CRK PK3CB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19380743 31980649
FLRT1 PK3CB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NLGN3 PK3CB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
P55G EHD2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FLRT1 P55G â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
AL3B1 P55G â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HAVR2 P55G â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
P55G NISCH â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CL059 P55G â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SRC P55G â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25814554 22402981
IRS4 P55G â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 25036637
NLGN3 P55G â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FLRT1 PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NLGN3 PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CL059 PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HAVR2 PK3CA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HAVR2 NISCH â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
IRS4 EGFR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16273093 24797263
EGFR IGF1R â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17047074 17307140
P85B P85A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 32203420 26186194 28514442 19380743
P85B P55G â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 19380743 26186194
TGFR2 PK3CB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
GRB2 PK3CB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 21706016
TGFR2 P55G â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SOCS6 P55G â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25814554 26186194
IRS4 PK3CA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 11912194
GRB2 PK3CA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 21706016 9565634 32814053 28514442 19380743
SOCS6 IRS4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12052866 28883622
P85B IRS1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11120660 30240640 12730242 23604317 7559478
IRS4 P85A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 33961781 25036637 18165436 11912194
SRC GRB2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12624098 9016807 16713569 16189514 11964172
IGF1R IRS1 â—¼   PHOSPHORYLATION ✅ + 0.85 0.85 Signor 17827393
GRB2 P55G â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 32296183 21706016
CRK P55G â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 25814554 19380743
PK3CA EGFR â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31959764 25754235 8561895 28628118 28205554 1845983
IRS4 GRB2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 9553137 21706016
P85A IGF1R â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 8697095 25241761 7589433 8603569 7642582
FAK1 P55G â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25814554 22402981 32296183
PK3CD P55G â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 32296183
ERBB3 PK3CA â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 11546794 24189400 19411071
CRK SRC â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
P85B PK3CD â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19380743 9113989
TGFR2 P85B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 26186194 9435577
FAK1 P85A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11119718 10973983 10806474 8649427 16713569 7537275 19889638 11104793
HAVR2 P85A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 26492563
CRK P85A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25241761 10962563 12878163 11418612 25814554 19380743
P85A TGFR2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 26186194 9435577
P55G RB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12588990 16189514
P55G IRS1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10417350 25814554 9415396 7542745
IRS2 P55G â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 10417350
P55G ERBB3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 22973453 16273093 24189400
EGFR SOCS6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 22973453 31980649 25402006 24658140
NISCH IRS4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 25036637 11912194
CRK EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
P85B GRB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20936779 8662998 19380743 21706016
P85B PK3CA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14681455 22402981 25253337 26496610 27684187 23604317 19380743
P85B CRK â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25814554 19380743 31980649
P85B PK3CB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 22402981 26186194 28514442 19380743 32707033
SRC P85A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19903481 23065768 32814053 23397142 10487518 25241761 24498420 19861161 16230374 12210743 16713569 7499252 12393736
P55G EGFR â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 24658140 31980649 22973453 25241761 25402006 16273093
IRS1 PK3CA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12933652 27684187 23643389 23604317 16354680 16150444 14511371
ERBB3 P85B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16273093 16729043 22973453 24189400
EGFR P85B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19531499 31959764 24658140 31980649 22973453 23956138 11172806 1334406 25402006 16273093
IRS2 P85A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12107746 9334184 15514089 26496610 8910607 19561084 12506011 23439647 11438664 9852124 21241768
P85A EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 19531499 21701776 7531698 31959764 22973453 8662998 25241761 16230374 7797556 25754235 25187647 16713569 7499252 16273093
CRK FAK1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 7529876 10085298 7509446 12370821 12615911 7561682 25814554 11314030
FAK1 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15657067 24658140 31980649 20473329 10806474 25402006 16713569
P55G IGF1R â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 9524259 25241761 17360667 9415396
IRS4 CRK â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11316748 9614078 16713569
EGFR CRK â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 10595738 9480911 9642287 24658140 31980649 11956190 16729043 22973453 8875975 25402006 9617486 16273093 12198159
ERBB3 EGFR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23436906 10527633 27756321 21278786 18803307 17148612 22439932 25315821 10572067 24189400 23866081
IRS2 GRB2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 19109239 7890616 9535722
IRS4 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9553137 15316024
GRB2 IRS1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
ERBB3 GRB2 â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
P55G PK3CB â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 28514442 25814554 22402981
P55G PK3CA â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 14681455 33961781 22402981 26496610 9415396 28514442 25814554
ERBB3 P85A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 15812817 11546794 20227043 21278786 11389077 22973453 10383151 9130710 24189400 21075308 9756944 12896906 18803287 22439932 11694521 10572067 16273093 20007781
PK3CB P85A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 27107012 24657164 26344197 32814053 22939629 25241761 26496610 8139559 26839216 21825134 10358930 32707033 20713702
PK3CD P85A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 32296183 18641334 21827948 26496610 31031754 24165795 22020336 9113989
P85A GRB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 7544353 8621719 18346204 7642581 16219545 32814053 7642542 20936779 16713569 19380743 21706016 7759531 8647120 25416956 9541596 9174058 11418612 7737969 9886492
P85A PK3CA â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22402981 20018188 26496610 23643389 26475863 26839216 11526404 16135792 32814053 27684187 7957566 15932879 28628118 16043515 20713702 15377662 9235916 25253337 19805105 19574958 33420362 7929193 24657164 19117013 28205554 9565634 18079394
FAK1 GRB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 10085298 7597091 20473329 7997267 10806474 21900206 8649427 12558988 12005431 16713569 8816475 16189514
SRC FAK1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 11927607 22402981 7997267 12387730 12558988 23242524 26264872 8941336 16291744 15987550 32814053 9822703 16713569 9507031 17525734 21855630 7529876 11119718 16966330 23065768 8816475 25814554 16189514 11104793 10085298 10931187 8054685 25241761 12615911 21034468 11980671
SRC EGFR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22227249 17284441 24658140 17158602 21278788 20333651 28065597 7527393 7797556 10777553 16713569 20624308 23175185 7506422 22973453 20935677 24189400 11983694 10075741 31980649 19704002 10358079 10971656 21268077 9020193 25402006 21573184 8845374
IRS1 GRB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 8810325 21706016 7486683 8536716 8388384 8491186 22974441 12173038 7488107 7629070
EGFR ERBB3 â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
IGF1R IRS1 â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
P85A IRS1 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 8382612 8175658 7680095 17640984 23643389 16230374 26839216 7659087 9564850 14511371 12220227 7486683 1381348 15514089 22974441 12730242 16043515 16150444 16354680 16880210 12107746 30240640 33991522 19561084 8628286 14632132 25814554 7935461 7680644 8388384 29526746 11416002 1334490 23439647 12173038 25273559 11403293
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GRB2 CRK â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 CRK â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
IGF1R CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 17145710 12198159 9642287 9480991 9480911 20068231 11956190 8194526 8875975 15522217 17016520
EGFR CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 52.0 1.0 Omnipath 10595738 9480991 16273093 9617486 25402006 17399949 8662907 8875975 21602891 20068231 8194526 12198159 9642287 11956190 24658140 26656091 9480911 31980649 15212693 26473374 16729043 17016520
IRS1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9837978 8810325 8621590
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17145710 23436906 7929151 21278786 24189400 23866081 17148612 12648464 27756321 18803307 10527633 10572067 22439932
ERBB3 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 9756944 24189400 11173924 24658140 14967450 16729043
IRS1 GRB2 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10086337 10826997 12175651 12444011 12767520 16931767 17604717 19030972 21540285 22465479 24036369 8621421
IRS1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 8265614 7862167 11788580 8388384 8491186 8536716 7488107 7486683 10358772 10592173 8196603 12173038 12679424 8114695 11259577 8810325
IRS2 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7559579 11788580 10358772 11305324 9852124
SRC GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12624098 11964172 9016807 16713569 26103942 20554525
IGF1R IRS1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10086337 10826997 11274345 12175651 12444011 12556535 12655147 12767520 16931767 17145802 17673906 19030972 21540285 24103846 24782617
SRC IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 17389395 15212693 18691976 7559478 7493944 7537849 20068231 23472139 8550552 17016520 8940173 9480911
IGF1R IRS4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 9553137 18988627 11316748
IGF1R IRS2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 8662806 9852124 10471495
IGF1R IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 7541045 12444011 19030972 10082579 16931767 21798082 12220227 11259577 12767520 10826997 23331499 17827393 7504175 21071413 7559507 11572799 27856640 12175651 17570479 15829723 18988627 15629149 11557037 20670944 8530377 21540285 8776723 25886138 8662806