Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
JAK1 ERBB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
ERBB2 JAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16273093
SMAD7 TGFB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10519551 19758997
SMAD7 TGFB2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15855641 19385040
RAB6B MTMR5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SMUF2 TGFR2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11163210 25149540
ACVL1 TGFR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 14580334 8242742
P55G P85A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TGFR2 NFIP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
SMAD7 BMR1A â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15148321 20663871
TGFR2 RAB6B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TGFR2 FMN2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
P85B P85A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 32203420 26186194 28514442 19380743
P85B P55G â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 19380743 26186194
TGFR1 P85A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15657037 9435577
TGFR2 PK3CB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TGFR2 P55G â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TGFR2 BMR1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TGFR2 AVR2B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TGFR2 PKN3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TGFR2 MTMR5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TGFR2 ERBB2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TGFR2 CDC6 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TGFR2 LRP10 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TGFR2 PTPRS â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TGFR2 PKHH3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TGFR2 FGFR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TGFR2 PKN2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TGFR2 MFAP3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TGFR2 MYADM â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 28443643
TGFR2 TR19L â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TGFR2 MARH7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 29794480 28514442 26186194 33961781
TGFR2 F116A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TGFR2 JAK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TGBR3 TGFB3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 21423151 11382746
SMUF2 TGFR1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23973329 31746425 21791611 25149540 11163210 14722617 26679521 22624557
TGFB2 TGFR2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11157754 8106553
STRAP SMAD7 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 17314099 10757800
TGFB2 TGFB1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 11157754 33961781 27684187 11483955
SMAD7 TGFR2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9335507 11163210 25149540
TGFB1 EGLN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 20856203 12015308 1326540 16189514
DAB2 TGFR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16713569 11387212
TGBR3 TGFR2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 8106553 11323414
FGFR1 P85A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 15117958 25241761 18412956 8321198
DAB2 TGFR2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16713569 11387212
STRAP TGFR2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9856985 10757800
TGFR2 P85B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 26186194 9435577
P85A TGFR2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 26186194 9435577
HS90A TGFR2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 22848678 18591668
ACVL1 TGFB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10716993 10187774 8242742
P85B PK3CB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 22402981 26186194 28514442 19380743 32707033
TGFB3 TGFR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11850637 21423151 10187774 12607775 12060054
HS90A TGFR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22848678 18591668 21465483
P85B ERBB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 22973453 16729043 16273093 1334406
SMUF2 SMAD7 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23973329 32283253 15221015 28292929 15231748 22773947 18448069 22921829 16061177 16641086 29235476 20937913 11163210 14722617 26435193 26679521 22624557 27292644
SMAD7 TGFR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17314099 25149540 11163210 10757800 16027725 12151385 15946939 20663871 22624557 15359284 14657019 9215638 23027871 21791611 9335507 15148321 14722617 19758997 31746425
TGFR2 TGFB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20856203 21054789 21441952 7706250 10026191 8389764 9261125 20860622 7878020 11157754 7935686 8242742
TGFB3 TGFR2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11850637 8106553 21423151 11382746 12729750 7878020 11157754 9872992
ERBB2 HS90A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25036637 26804907 17239458 22315411 18655187 24658140 23995768 21503962 24189400 20558745 11071886 12006493 20159553 22939624 16144943 21812426
ACVL1 TGFR2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 23868260 10716993 10187774
STRAP TGFR1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 9856985 17314099 10757800
P85A ERBB2 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 7531698 22973453 16843263 21075308 9756944 12896906 16273093 1351056
TGFR2 EGLN â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 12015308 15702480 9872992
EGLN ACVL1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 10767348 28564608 23868260 15702480
TGFR1 TGFB1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 20856203 7706250 15597342 10716993 8235612 10187774
TGFR1 EGLN â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 18974388 23868260 12015308 15702480 9872992
P55G PK3CB â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 28514442 25814554 22402981
TGBR3 TGFB1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 20856203 10519421 8106553 9312157 11323414 7935686
TGFR2 TGFR1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 8576253 10026191 19556242 11483955 21791611 23868260 7890683 21423151 25825445 11102446 7878020 19758997
PK3CB P85A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 27107012 24657164 26344197 32814053 22939629 25241761 26496610 8139559 26839216 21825134 10358930 32707033 20713702
TGFB1 SMAD7 â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11133108 11708773 12490555 14557817 15111329 15181457 15252039 15548370 16474430 16607286 16716598 17615296 17934056 18403754 19010789 19109155 19920116 20519943 20644162 21041997 21278795 21900405 21909923 22703233 7594497 9157999 9335507
SMAD7 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 10887185 15855807 9886263 20631490 22656308 19214138 23633623 14600158 10753944 11912247 11385614 11180003 17928287 19010789 22496417 22841502 17074765 15496141 11448947
TGFB1 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19010789 14718519 16474430 17934056 20519943 9335507 21900405 11133108 14557817 15548370 19920116
SMAD7 STRAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 17314099 10757800