Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SMAD5 NEDD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD1 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMUF2 UB2D1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 20858899 25723849 32669362 24709419
EGFR SMUF2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 33762435 21750651 32669362
SEMG2 SMUF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SMUF2 TGFR2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11163210 25149540
SMUF2 SYMM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
LIGO2 SMUF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RNF11 UB2D1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19690564 14562029 32296183 19549727
SMAD2 KLF5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19419955 18729074
SMAD1 NEDD4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15231748 21308777
DAZP2 SMUF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22070932 15231748 16713569
SMUF2 CUED1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 33099540 15231748
CR001 SMUF2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TGFR1 SMUF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11278251 12857866 14657019
SMAD2 SMUF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15221015 20207742 15231748
RNF11 SMUF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 32814053 28292929 15231748
CR001 SMUF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CR001 SMAD3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CR001 NEDD4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CR001 CUED1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CR001 SMAD2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SMAD6 SMUF2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24850914 15761153 15221015 15231748
SMUF2 KLF5 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 34035464 21953463
SMUF2 TGFR1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23973329 31746425 21791611 25149540 11163210 14722617 26679521 22624557
SMAD3 SMUF1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15221015 15231748 19917253 15761153 28839186
SMAD1 SMAD3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15761153 9111321 18729074
SMAD7 TGFR2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9335507 11163210 25149540
SMAD1 SMAD6 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
SMAD3 NEDD4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19953087 15496141 21685363 32296183
SMUF2 SMUF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 21897371 27086113 18451154 28514442 18927080
SMUF1 TRAF4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19937093 23973329
NEDD4 EGFR â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 19953087 33762435 29455656
SMAD7 SMAD6 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 26555259 9256479
SMAD2 SMAD1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 28205554 28628118 9111321 18729074
RNF11 SMUF2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28292929 14562029 15231748 14755250 31985874 20676133
SMUF2 UB2L3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17719543 29964046 17996703 31628949 25723849 16061177 29263404 20858899 27182664 26949039 30587574
TRAF4 SMUF2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23973329 15231748
NEDD4 SMUF2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 28514442 15496141 25438670 33961781
TGFR1 SMAD2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9525694 9892009 29490279 19139564 23687300 11102446 25872870 9346908 12543979 18511908 15350225
UB2L3 NEDD4 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 17719543 18498246 23549616 20086093 17996703 20051513 28300060 29263404 25292214 9990509 19240029 12890487 27182664 21986318 21953697 26949039 30587574
SMAD5 SMUF1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11278251 15221015 19914168 15231748 22670624 17676934 20484049 18641638 12857866 16516194
SMAD6 SMAD1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9256479 12857866 9436979 11483516
SMAD2 SMAD3 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
SMUF2 SMAD3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23973329 15221015 32296183 19917253 19122240 28881580 28839186 11389444 11158580 18729074 33990575 11016919 22045334
SMUF2 SMAD2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15221015 19620243 15231748 19122240 28468752 28881580 11389444 11158580 20937913 18729074 11016919
SMUF2 SMAD1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 15221015 32296183 15231748 19917253 28468752 11158580 20937913 28514442 11016919 14701756
SMUF2 SMAD7 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23973329 32283253 15221015 28292929 15231748 22773947 18448069 22921829 16061177 16641086 29235476 20937913 11163210 14722617 26435193 26679521 22624557 27292644
SMAD7 TGFR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17314099 25149540 11163210 10757800 16027725 12151385 15946939 20663871 22624557 15359284 14657019 9215638 23027871 21791611 9335507 15148321 14722617 19758997 31746425
SMUF1 SMAD7 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11278251 12151385 15221015 16720724 23959799 22921829 12519765 24700460 20937913 14722617 22152476 22773947 27292644
SMAD2 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18729074 9111321
SMAD6 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9892110
SMUF1 SMAD6 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 11278251 15221015 21897371 17676934 28847510 29950561
SMUF2 SMAD5 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 15221015 15231748 20484049 28514442
SMUF2 RHG05 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 28514442 15231748
SMAD1 SMUF1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 21708152 19914168 15221015 15231748 19917253 22670624 15761153 21685363 28881580 17676934 17289590 17510966 16611643 22152476 14701756 24828823
RNF11 NEDD4 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 28292929 15231748 11042109 31985874 20676133 19953087
TGFR2 TGFR1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 8576253 10026191 19556242 11483955 21791611 23868260 7890683 21423151 25825445 11102446 7878020 19758997
SMAD1 SMAD6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10692396 17215250 22219353 22072987
SMAD6 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 9256479 9335505 9436979 21071413 18988627 11483516 12857866
SMAD3 SMAD2 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
SMAD2 SMAD7 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD2 SMAD7 â—¼   DOWN_REGULATES ✅ - 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD2 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15183844 10887185 10753944 10843994 10559222
SMAD7 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 17438144 21071413 9892009 9892110
SMAD6 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 9256479 21071413 9892110
SMAD2 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 26186194 12543979 9111321 15084259 9311995 25878769 18729074 12700238
SMAD3 SMAD7 â—¼   PHYSICAL_INTERACTION 13.0 1.0 ACSN 11279127 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21614932 22331441 23784029 8515656
SMAD3 SMAD7 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11279127 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21614932 22331441 23784029 8515656
SMAD3 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10823886 15183844 12761881 10887185 10973944 10839991 10753944 10843994 15579469 10559222
SMAD7 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 21071413 9892009 26555259 9892110
SMAD5 SMAD6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10692396 16436528 22219353