Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SMAD5 NEDD4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
SMAD1 SMAD5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 15231748 5217094
EGFR SMUF2 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32669362 21750651 33762435
SMUF2 UB2D1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32669362 25723849 20858899 24709419
SMAD1 NEDD4 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15231748 21308777
RNF11 UB2D1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19690564 14562029 19549727 32296183
SMAD2 KLF5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19419955 18729074
SMUF2 TGFR2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 11163210 25149540
SMUF2 SYMM â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
LIGO2 SMUF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
SEMG2 SMUF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CR001 NEDD4 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
RNF11 SMUF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 32814053 15231748 28292929
CR001 SMAD2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
SMAD2 SMUF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15231748 15221015 20207742
CR001 SMAD3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
SMUF2 CUED1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15231748 33961781 33099540
DAZP2 SMUF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15231748 22070932 16713569
CR001 SMUF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
TGFR1 SMUF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14657019 12857866 11278251
CR001 SMUF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
CR001 CUED1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
SMAD1 SMAD3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9111321 15761153 18729074
SMAD3 SMUF1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28839186 15761153 15231748 15221015 19917253
SMAD6 SMUF2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 15761153 15221015 15231748 24850914
SMUF2 KLF5 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21953463 34035464
SMUF2 TGFR1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22624557 26679521 31746425 14722617 21791611 11163210 23973329 25149540
SMAD7 TGFR2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9335507 11163210 25149540
SMAD1 SMAD6 â—¼   PHYSICAL_INTERACTION 855.0 0.85 STRING 36370105
SMAD3 NEDD4 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 19953087 32296183 15496141 21685363
NEDD4 EGFR â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 19953087 33762435 29455656
SMAD7 SMAD6 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26555259 9256479
SMUF2 SMUF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 18927080 27086113 33961781 18451154 21897371
SMUF1 TRAF4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23973329 19937093
SMAD2 SMAD1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9111321 28628118 18729074 28205554
UB2L3 NEDD4 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20051513 19240029 25292214 12890487 20086093 29263404 21986318 18498246 21953697 30587574 23549616 28300060 27182664 17719543 17996703 26949039 9990509
NEDD4 SMUF2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 15496141 33961781 25438670
RNF11 SMUF2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14562029 28292929 31985874 20676133 15231748 14755250
TGFR1 SMAD2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19139564 9346908 15350225 18511908 25872870 23687300 11102446 29490279 9525694 9892009 12543979
SMAD6 SMAD1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11483516 12857866 9436979 9256479
SMAD5 SMUF1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17676934 11278251 20484049 22670624 12857866 18641638 19914168 16516194 15231748 15221015
TRAF4 SMUF2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 15231748 23973329
SMUF2 UB2L3 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 29964046 16061177 30587574 31628949 20858899 27182664 25723849 17719543 17996703 26949039 29263404
SMUF1 SMAD7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15221015 22921829 23959799 11278251 22773947 22152476 16720724 24700460 14722617 12519765 20937913 27292644 12151385
SMUF2 SMAD7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22921829 18448069 22624557 16061177 22773947 26679521 26435193 28292929 29235476 32283253 14722617 11163210 16641086 20937913 23973329 15231748 27292644 15221015
SMAD7 TGFR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15148321 14657019 15946939 19758997 14722617 20663871 25149540 23027871 12151385 9215638 21791611 17314099 15359284 10757800 22624557 9335507 31746425 11163210 16027725
SMAD2 SMAD3 â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
SMUF2 SMAD2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18729074 28881580 19122240 19620243 28468752 11158580 20937913 15231748 11016919 15221015 11389444
SMAD2 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18729074 9111321
SMUF2 SMAD3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 28839186 18729074 28881580 19122240 33990575 11158580 23973329 22045334 11016919 15221015 19917253 11389444
SMAD6 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 9892110
SMUF2 SMAD1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 32296183 14701756 28468752 11158580 33961781 20937913 15231748 11016919 15221015 19917253
SMUF1 SMAD6 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 15221015 11278251 29950561 17676934 28847510 21897371
SMUF2 SMAD5 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 20484049 33961781 15231748 15221015
SMUF2 RHG05 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 15231748 33961781
RNF11 NEDD4 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28292929 19953087 31985874 11042109 20676133 15231748
SMAD1 SMUF1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 17676934 17510966 24828823 28881580 14701756 21708152 16611643 22152476 21685363 22670624 15761153 19914168 15231748 17289590 15221015 19917253
TGFR2 TGFR1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19556242 21423151 7878020 10026191 8576253 19758997 21791611 11483955 33961781 11102446 25825445 23868260 7890683
SMAD3 SMAD7 â—¼   PHYSICAL_INTERACTION 13.0 1.0 ACSN 11279127 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21614932 22331441 23784029 8515656
SMAD2 SMAD7 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD2 SMAD7 â—¼   PROTEIN_INTERACTION 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD3 SMAD7 â—¼   PROTEIN_INTERACTION 13.0 1.0 ACSN 11279127 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21614932 22331441 23784029 8515656
SMAD2 SMAD7 â—¼   DOWN_REGULATES ✅ - 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD3 SMAD7 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11279127 11792802 12702545 12809600 15265520 16179589 16713975 18768831 21042762 21614932 22331441 23784029 8515656
SMAD3 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 10823886 15183844 12761881 10887185 10973944 10839991 10753944 10843994 15579469 10559222
SMAD2 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15183844 10887185 10753944 10843994 10559222
SMAD7 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23331499 21071413 9892009 26555259 9892110
SMAD7 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 17438144 21071413 9892009 9892110
SMAD3 SMAD2 â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
SMAD3 SMAD2 â—¼   PROTEIN_INTERACTION 41.0 1.0 ACSN 10454538 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11792802 12545156 12702545 12809600 15001984 15095404 15155580 15265520 16179589 16713975 17055429 17550342 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23869868 8515656 9312026 9389648 9618481 9670020 9865696
SMAD6 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 23331499 9256479 21071413 9892110
SMAD2 SMAD3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 21988832 26186194 12543979 9111321 15084259 9311995 25878769 18729074 12700238
SMAD1 SMAD6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10692396 17215250 22219353 22072987
SMAD6 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 23331499 9256479 9335505 9436979 21071413 18988627 11483516 12857866
SMAD5 SMAD6 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10692396 16436528 22219353