Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SMAD7 TGFB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10519551 19758997
TGFB1 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21358634 9679059
DAB2 AP2B1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22323290 34079125
SMUF2 TGFR2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 11163210 25149540
PAR6A TGFR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 15761153 15761148
ACVL1 TGFR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 14580334 8242742
SMAD2 SMUF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15231748 15221015 20207742
TGFR1 M3K7 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19556242 18758450 23973329
TGFR1 SMUF1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14657019 12857866 11278251
TGFA1 TGFR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 9545258 11278302
TGFR1 P85A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 15657037 9435577
STRAP SMAD7 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17314099 10757800
AP2B1 TGFR1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12429842
SMUF2 TGFR1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22624557 26679521 31746425 14722617 21791611 11163210 23973329 25149540
SMAD4 TGFR1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 8774881 15761153 11102446
SMAD7 TGFR2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9335507 11163210 25149540
TGFB1 EGLN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 12015308 16189514 20856203 1326540
DAB2 TGFR1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11387212 16713569
STRAP TGFR2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9856985 10757800
TRAF6 TGFR1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18922473 18758450 26807171 24103590 25622187
CAV1 TGFR1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 30745168 11102446
DAB2 TGFR2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11387212 16713569
SMUF2 SMUF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 18927080 27086113 33961781 18451154 21897371
SMAD4 SMAD7 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
TGFR1 CD44 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12145287 15597342
TGFA1 SMAD4 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 11278302
ACVL1 TGFB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10716993 10187774 8242742
P85A TGFR2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 28514442 33961781 9435577 26186194
HS90A TGFR2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18591668 22848678
TGFR1 SMAD2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 19139564 9346908 15350225 18511908 25872870 23687300 11102446 29490279 9525694 9892009 12543979
SMAD2 DAB2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 11387212 16713569
TGFB3 TGFR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21423151 12607775 11850637 10187774 12060054
HS90A TGFR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21465483 18591668 22848678
SMAD2 STRAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10757800
STRAP SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10757800
M3K7 TRAF6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 31127032 22924441 28024152 10921914 27249171 19232515 10882101 16543409 19675569 24434549 10094049 33768585 18758450 19521662 11259596 22851693 19843958 12496252 11518704 14633987 12242293 21822258 19112497 27501752 19820695 16517750 22643835 26038599 31885808 25963657 12609980 31404116
SMAD2 SMAD4 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9111321 25514493 11927552 28443643 21988832 20211142 15467747 12732634 25609649 15922743 12419246 9288972 21454478 19139564 24157709 18729074 22442258 17283070 16916642 15350224 17591701 11274206 15761153 31591477 26555259 9892009 9311995 10085121 9389648 10781087 12167862 10878024 18783722 27703004 18511908 28468752 19135894 10531362 12794086 15231748 21297662 12621041 19917253 11027280 24584437 16751102 31932471 10199400 21532621 12808092 33961781 11264182 11102446 11114293 12543979 23788427 15817471
SMAD7 SMAD4 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11279127 15265520 23784029
SMUF1 SMAD7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15221015 22921829 23959799 11278251 22773947 22152476 16720724 24700460 14722617 12519765 20937913 27292644 12151385
SMUF2 SMAD7 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22921829 18448069 22624557 16061177 22773947 26679521 26435193 28292929 29235476 32283253 14722617 11163210 16641086 20937913 23973329 15231748 27292644 15221015
SMAD7 TGFR1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15148321 14657019 15946939 19758997 14722617 20663871 25149540 23027871 12151385 9215638 21791611 17314099 15359284 10757800 22624557 9335507 31746425 11163210 16027725
SMUF2 SMAD2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18729074 28881580 19122240 19620243 28468752 11158580 20937913 15231748 11016919 15221015 11389444
SMAD2 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 27974707 11456453 16284942
TGFR2 TGFB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8389764 7878020 7935686 7706250 10026191 21054789 20860622 11157754 9261125 20856203 8242742 21441952
TGFB3 TGFR2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21423151 7878020 11382746 11850637 9872992 11157754 8106553 12729750
ACVL1 TGFR2 â—¼   PROTEIN_INTERACTION 0.91 0.91 HIPPIE 10716993 10187774 23868260
STRAP TGFR1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 9856985 17314099 10757800
TGFR2 EGLN â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 15702480 12015308 9872992
EGLN ACVL1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 15702480 28564608 10767348 23868260
TGFR1 TGFB1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 10716993 7706250 15597342 10187774 20856203 8235612
TGFR1 EGLN â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9872992 18974388 15702480 12015308 23868260
M3K7 HS90A â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 32707033 14743216 19026643
TGFR2 TGFR1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19556242 21423151 7878020 10026191 8576253 19758997 21791611 11483955 33961781 11102446 25825445 23868260 7890683
TGFR1 FKB1A â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16049346 7518616 24658140 7791754 9346894 10025408
SMAD7 STRAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 17314099 10757800
TGFB1 TRAF6 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 11013220 11133108 12154066 12717440 12724770 12767520 12809600 14557817 15265520 15548370 16474430 17673906 17934056 18758450 18922473 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 22943793 24132110 24336330 7594497 9865696
TGFB1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18922473 22710166 19010789 16474430 22943793 17934056 20519943 12809600 21900405 11133108 18758450 14557817 15548370 19920116
SMAD2 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
SMAD4 SMAD2 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11399519 11792802 11875494 12193690 12545156 12702545 12809600 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 17055429 17260466 17550342 17689680 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23390297 23784029 23869868 6357187 8515656 8871614 9312026 9389648 9618481 9670020
SMAD4 SMAD2 â—¼   PROTEIN_INTERACTION 52.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11399519 11792802 11875494 12193690 12545156 12702545 12809600 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 17055429 17260466 17550342 17689680 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23390297 23784029 23869868 6357187 8515656 8871614 9312026 9389648 9618481 9670020
SMAD2 SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16052471 11376804 11456453 9812998
SMAD4 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10823886 15183844 10887185 19032343 10839991 16442497 10753944 10843994 15128733 10559222
SMAD4 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10964912 15647271 10843986 21968601
SMAD2 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 110.0 1.0 Omnipath 15613484 17145710 25609649 15817471 20211142 21532621 24584437 18729074 23788427 12419246 16916642 9288972 9892009 21454478 17510063 10531362 15231748 11027280 12167862 21988832 9389648 23331499 12543979 18568018 21071413 19135894 18511908 15467747 12808092 11927552 25514493 15350224 18988627 12732634 10878024 9111321 9311995 9346908 10199400 11264182 12957874 11114293 15761153 11274206 12621041 17272273 24157709 26555259 12374795 22442258 10781087 15922743 11102446 17591701 18783722 16751102 19139564 19917253 9346966 21297662 17283070 12794086
SMAD2 SMAD7 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD2 SMAD7 â—¼   PROTEIN_INTERACTION 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD2 SMAD7 â—¼   DOWN_REGULATES ✅ - 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
TGFB1 SMAD7 â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11133108 11708773 12490555 14557817 15111329 15181457 15252039 15548370 16474430 16607286 16716598 17615296 17934056 18403754 19010789 19109155 19920116 20519943 20644162 21041997 21278795 21900405 21909923 22703233 7594497 9157999 9335507
SMAD2 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15183844 10887185 10753944 10843994 10559222
SMAD7 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 10887185 15855807 9886263 20631490 22656308 19214138 23633623 14600158 10753944 11912247 11385614 11180003 17928287 19010789 22496417 22841502 17074765 15496141 11448947
TGFB1 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19010789 14718519 16474430 17934056 20519943 9335507 21900405 11133108 14557817 15548370 19920116
SMAD7 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 17438144 21071413 9892009 9892110
TGFB1 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 30.0 1.0 ACSN 10678166 11013220 11133108 11278410 11792802 12154066 12717440 12724770 14557817 15265520 15548370 16474430 17934056 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 24132110 24336330 7594497 9311995 9865696
DAB2 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 11387212
TGFB1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 15548370 19010789 10678166 16474430 9311995 23831640 17934056 20519943 24075003 11792802 11133108 21900405 14557817 11278410 19920116 9865696