Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...

Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TGFB1 SMAD2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 21358634 9679059
SMAD7 TGFB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 10519551 19758997
SMUF2 TGFR2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 11163210 25149540
PAR6A TGFR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15761148 15761153
ACVL1 TGFR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 14580334 8242742
DAB2 AP2B1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22323290 34079125
TGFR1 SMUF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11278251 12857866 14657019
TGFR1 M3K7 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23973329 18758450 19556242
TGFR1 P85A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15657037 9435577
TGFA1 TGFR1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 11278302 9545258
SMAD2 SMUF1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 15221015 20207742 15231748
SMUF2 TGFR1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 23973329 31746425 21791611 25149540 11163210 14722617 26679521 22624557
AP2B1 TGFR1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12429842
STRAP SMAD7 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 17314099 10757800
SMAD4 TGFR1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15761153 8774881 11102446
SMAD7 TGFR2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 9335507 11163210 25149540
TGFB1 EGLN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 20856203 12015308 1326540 16189514
DAB2 TGFR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16713569 11387212
SMUF2 SMUF1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 21897371 27086113 18451154 28514442 18927080
TRAF6 TGFR1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25622187 18758450 26807171 24103590 18922473
CAV1 TGFR1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 30745168 11102446
DAB2 TGFR2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16713569 11387212
STRAP TGFR2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 9856985 10757800
SMAD4 SMAD7 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
TGFR1 CD44 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15597342 12145287
P85A TGFR2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 28514442 26186194 9435577
HS90A TGFR2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 22848678 18591668
ACVL1 TGFB1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10716993 10187774 8242742
TGFA1 SMAD4 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11278302 16189514
TGFR1 SMAD2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 9525694 9892009 29490279 19139564 23687300 11102446 25872870 9346908 12543979 18511908 15350225
TGFB3 TGFR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11850637 21423151 10187774 12607775 12060054
HS90A TGFR1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22848678 18591668 21465483
SMAD2 DAB2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16713569 11387212
SMUF2 SMAD2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15221015 19620243 15231748 19122240 28468752 28881580 11389444 11158580 20937913 18729074 11016919
SMUF2 SMAD7 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23973329 32283253 15221015 28292929 15231748 22773947 18448069 22921829 16061177 16641086 29235476 20937913 11163210 14722617 26435193 26679521 22624557 27292644
SMAD7 TGFR1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17314099 25149540 11163210 10757800 16027725 12151385 15946939 20663871 22624557 15359284 14657019 9215638 23027871 21791611 9335507 15148321 14722617 19758997 31746425
TGFR2 TGFB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20856203 21054789 21441952 7706250 10026191 8389764 9261125 20860622 7878020 11157754 7935686 8242742
TGFB3 TGFR2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11850637 8106553 21423151 11382746 12729750 7878020 11157754 9872992
M3K7 TRAF6 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31127032 16543409 22851693 11518704 21822258 27249171 12242293 31885808 19843958 22643835 19112497 33768585 28024152 12609980 10921914 11259596 19521662 10882101 16517750 14633987 18758450 12496252 31404116 22924441 24434549 19232515 26038599 10094049 19820695 27501752 25963657 19675569
SMUF1 SMAD7 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 11278251 12151385 15221015 16720724 23959799 22921829 12519765 24700460 20937913 14722617 22152476 22773947 27292644
SMAD2 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 27974707 11456453 16284942
STRAP SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10757800
SMAD2 STRAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 10757800
SMAD7 SMAD4 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11279127 15265520 23784029
ACVL1 TGFR2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 23868260 10716993 10187774
STRAP TGFR1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 9856985 17314099 10757800
TGFR2 EGLN â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 12015308 15702480 9872992
EGLN ACVL1 â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 10767348 28564608 23868260 15702480
TGFR1 TGFB1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 20856203 7706250 15597342 10716993 8235612 10187774
TGFR1 EGLN â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 18974388 23868260 12015308 15702480 9872992
M3K7 HS90A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 32707033 14743216 19026643
TGFR1 FKB1A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 7791754 9346894 10025408 7518616 24658140 16049346
TGFR2 TGFR1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 8576253 10026191 19556242 11483955 21791611 23868260 7890683 21423151 25825445 11102446 7878020 19758997
SMAD2 SMAD4 â—¼   PHYSICAL_INTERACTION 999.0 0.99 STRING 36370105
DAB2 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 16713569 11387212
SMAD4 SMAD2 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10454538 10925299 10964912 11007770 11013220 11074002 11279127 11283613 11283614 11399519 11792802 11875494 12193690 12545156 12702545 12809600 15001984 15095404 15155580 15265520 15644117 16127449 16179589 16713975 17055429 17260466 17550342 17689680 17705132 18353785 18768831 19815509 19901969 20027199 20713526 21042762 21252118 21614932 2191300 22331441 23140366 23338822 23390297 23784029 23869868 6357187 8515656 8871614 9312026 9389648 9618481 9670020
SMAD2 SMAD7 â—¼   PHYSICAL_INTERACTION 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
TGFB1 SMAD2 â—¼   ENZYMATIC_REACTION ✅ 30.0 1.0 ACSN 10678166 11013220 11133108 11278410 11792802 12154066 12717440 12724770 14557817 15265520 15548370 16474430 17934056 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 24132110 24336330 7594497 9311995 9865696
SMAD2 SMAD7 â—¼   DOWN_REGULATES ✅ - 10.0 1.0 ACSN 11074002 11279127 15265520 16179589 16713975 21042762 21614932 22331441 23784029 9670020
SMAD2 SMAD4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 16052471 11376804 11456453 9812998
SMAD2 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15183844 10887185 10753944 10843994 10559222
SMAD7 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 23331499 17438144 21071413 9892009 9892110
TGFB1 SMAD2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 15548370 19010789 10678166 16474430 9311995 23831640 17934056 20519943 24075003 11792802 11133108 21900405 14557817 11278410 19920116 9865696
SMAD2 SMAD4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 110.0 1.0 Omnipath 15613484 17145710 25609649 15817471 20211142 21532621 24584437 18729074 23788427 12419246 16916642 9288972 9892009 21454478 17510063 10531362 15231748 11027280 12167862 21988832 9389648 23331499 12543979 18568018 21071413 19135894 18511908 15467747 12808092 11927552 25514493 15350224 18988627 12732634 10878024 9111321 9311995 9346908 10199400 11264182 12957874 11114293 15761153 11274206 12621041 17272273 24157709 26555259 12374795 22442258 10781087 15922743 11102446 17591701 18783722 16751102 19139564 19917253 9346966 21297662 17283070 12794086
SMAD4 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10964912 15647271 10843986 21968601
SMAD4 SMAD7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10823886 15183844 10887185 19032343 10839991 16442497 10753944 10843994 15128733 10559222
TGFB1 SMAD7 â—¼   UP_REGULATES ✅ + 27.0 1.0 ACSN 11133108 11708773 12490555 14557817 15111329 15181457 15252039 15548370 16474430 16607286 16716598 17615296 17934056 18403754 19010789 19109155 19920116 20519943 20644162 21041997 21278795 21900405 21909923 22703233 7594497 9157999 9335507
SMAD7 TGFB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 10887185 15855807 9886263 20631490 22656308 19214138 23633623 14600158 10753944 11912247 11385614 11180003 17928287 19010789 22496417 22841502 17074765 15496141 11448947
TGFB1 SMAD7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 19010789 14718519 16474430 17934056 20519943 9335507 21900405 11133108 14557817 15548370 19920116
SMAD7 STRAP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 17314099 10757800
TGFB1 TRAF6 â—¼   ENZYMATIC_REACTION ✅ 32.0 1.0 ACSN 11013220 11133108 12154066 12717440 12724770 12767520 12809600 14557817 15265520 15548370 16474430 17673906 17934056 18758450 18922473 19010789 19050695 19109155 19920116 20060931 20519943 20644162 21278795 21614932 21900405 22703233 22710166 22943793 24132110 24336330 7594497 9865696
TGFB1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 18922473 22710166 19010789 16474430 22943793 17934056 20519943 12809600 21900405 11133108 18758450 14557817 15548370 19920116