Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SRC FANCA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
MTOR TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
MTOR AKT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214238 11438723
AKT1 MTOR â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 17611497 18954143
AKT1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17942906 9804616
TRAF2 TANK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
NCOA3 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16877447 20305690
NFKB1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18031796
CBP SRC â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 16860316 15615775 16713569 22364282
IKKA P53 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 32707033 11805286 16713569 17434128
FANCA HS90A â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30844655 14499622
IKKB FKBP5 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 21903422
FKBP5 NEMO â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 33961781 25036637
NEMO KEAP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20600852 30500824
IKKA KEAP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20600852 30500824
IKKA MTOR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18519641 18490760
IKKB MTOR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 18519641 18490760
MYC ELP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17314511 29467282
BCL10 IKKA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 11113112 22547678 14695475
IKKA RIPK1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 10980203 29955050
RIPK1 HS90B â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939624 14743216
IRAK1 IKKB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 11096118 18180283
IRAK1 IKKA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 11096118 18180283
PSG1 IKKA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
PSG1 IKKB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
F196A NEMO â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CNTN2 IKKB â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16424386 17891179
F196A IKKA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CNTN2 IKKA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16424386 17891179
E2AK2 CDC37 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 23455922 33961781 24189400
CDC37 FKBP5 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33961781 25036637 24981860
KEAP1 HS90A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 20864537 24127568 26517842
TRAF2 MTOR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14743216 25241761
IKKA TANK â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 12133833 30561431
TRAF2 HS90B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14743216 25241761
TRAF2 CIKS â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 16713569 15485634 21822258 30892082
ARRB2 SRC â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 19202075 19122674 11877451 23242524
ARRB2 IKKA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25241761 17620599
ARRB2 PPM1B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25241761 17620599
NCOA3 TF65 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16331275 16456540
NEMO CBP â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14597638 11971985
PPM1B NEMO â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16189514 14585847
NEMO CNTN2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 33362245 16424386 16611882 17942533 17891179 19064727
M3K3 IKKB â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 11429546 14743216
IKKA M3K3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 14743216 25241761
PPM1B IKKA â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25241761 14585847
M3K7 M3K3 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16260783 19843958
CTNB1 HS90B â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31536960 27684187 15492215
CTNB1 HS90A â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31536960 27684187 32814053
FKBP5 MTOR â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
IRAK1 CDC37 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 15647277
AKT1 FANCA â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14499622 11855836
MYC HS90A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12644583 29467282 28914785
SRC IKKA â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12707358 15749833
NEMO AKT1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 20098747 20837477
NFKB1 HS90B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14743216 25241761 25609649
CBP IKKB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14597638 25241761 11971985
TF65 P53 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 28205554 28628118 17434128
IKKA E2AK2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10723127 10848580 10648614
E2AK2 HS90A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22939624 23455922 11447118
ELP1 IKKB â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9751059 16713569
IKKB HS90B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 14743216 25241761
M3K7 HS90B â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 14743216
AKT2 HS90A â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 22939624 11988487
ARRB2 SRC â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
HS90B SRC â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 28215707 31980649
SRC IKBA â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 12429743 9792645 33961781 26186194 8797825
AKT2 AKT1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 28514442 12149249 9736715 12176337 11445557 33961781 14500673 11278835 11546794
AKT1 CBP â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 19995607 23434580
HS90A IRAK1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 15647277
P53 IKKB â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 19883646 19196987
NEMO M3K7 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 34535633 23986494 21606198 17363973 30404796 19531477 33139544 32731169
ELP1 IKKA â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9751059 16713569 10094049
PPM1B M3K7 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 11104763
FANCA IKKA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14499622 12210728
BCL10 IKKB â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11113112 19118383 14695475 17213322
TRAF2 NEMO â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10980203 28249776 31502302 23007157 12867425
SRC IKKB â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12707358 15749833 12645577 15456896
SRC NEMO â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 23131831 15749833
ARRB2 IKBA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15125834 15173580
CIKS IKKA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 12943667 10962033
IKKA HS90B â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 33961781
HS90A M3K3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 14743216 19560753
AKT1 CDC37 â—¼   PHYSICAL_INTERACTION 869.0 0.87 STRING 36370105
TF65 KEAP1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 21262351 21988832
IKKA MYC â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 33461590 21575199
RIPK1 M3K7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16543241 21606198 24434549 18570872
CTNB1 NFKB1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 15829968 25241761 19358846
P73 P53 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 9802988 25417702 21508668 9891077 11238924
AKT2 IKKA â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 17962807 12048203
M3K14 M3K7 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10807933 10094049
CDC37 AKT1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22504172 12176997 31980649 24869908
M3K7 FKBP5 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32707033 14743216 33961781
FKBP5 IKKA â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14743216 33961781 25036637
MYC TF65 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 15616592 16713569 28628118 28205554 12027803
BCL10 TRAF2 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32296183 25416956 16713569 10753917 25910212 33961781 11466612
RIPK1 HS90A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22939624 14743216 16968706 10744744
NFKB2 NEMO â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14743216 21131783
NEMO IKBB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14743216 33961781 11485410 21862596
IKKA P73 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17452332 21482671
NEMO HS90A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14743216 16189514 11864612 26496610 33961781 19875381
CIKS IKKB â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 12943667 10962033 24561578
IKKB CTNB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25241761 11527961
IKKB HS90A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14743216 19786027 11864612
IKKB TF65 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25241761 17962807 10521409 22689577 18519641 12842894 16046471 15489227 29084252
IKKA HS90A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14743216 11864612 22384180 33961781 19875381
IKKA CTNB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 11527961 12589056
IKKA ML12A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 14743216 22863883
M3K14 CDC37 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14743216 25036637 31980649 32707033 30833792
P73 MYC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12080043 11844794
MYC CBP â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 35140242 16878156 12776737 29467282
MYC P53 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 21150319 30415952 28628118 28205554
TRAF2 M3K7 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32024699 14743216 26299341 17384642 14633987
HS90A SRC â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 31980649 1310678 16844778 22315411 28537252 32707033
HS90B AKT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 10995457 20650008 31980649
AKT1 IKKA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25241761 17962807 10485711 15710601 15800029 10485710 11278366
NCOA3 NEMO â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16051665 11971985
IKBB IKKA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14743216 9346485 11485410 33961781 9252186 9689078
CIKS NEMO â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16189514 10962033 12943667 10962024
NEMO HS90B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14743216 33961781 26496610 24618592
M3K7 IKKB â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34535633 31127032 10022904 10779355 18316610 27387502 17363905 24270572 17363973 32410369 27693634 10807933 18456659 26334375 10195894 9689078 21331078 33895773 20932476 11460167 25946971
IKKA MYH14 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 32707033 14743216 22863883
M3K7 IKKA â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16893890 25241761 20200282 33895773 34535633 10094049 10187861 9742107
HS90A M3K14 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 14743216 31980649 22939624 17563756 32707033 30833792
M3K14 HS90B â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22939624 14743216 32707033 31980649
TANK TRAF2 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
CDC37 MTOR â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CDC37 NEMO â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14743216 11864612 25036637 24618592 24189400 26496610 33961781
CDC37 SRC â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32707033 33961781 31980649 11085988
CDC37 IKKA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14743216 25036637 11864612 24189400 33961781 32707033 21903422
CDC37 IKKB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14743216 25036637 11864612 26496610 33961781 21903422
FKBP5 HS90A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20048054 20661446 25036637 9001212 12538866 22863883 10642522 21235734 21170051 21360678 29079741 23999428 28363942 19875381
FKBP5 HS90B â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 30382094 25036637 21170051
MTOR AKT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 18566587 25792870 15718470 14970221 24670654 10910062 18505677 29567957 22337773 21177249 26293922 19299511 18566586 30639242 21045808 11438723 22084251 23872070 21343617 22307628
MYC AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16846534 16489011 18562319
NFKB1 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 2191300 18490439 19219071
TANK NEMO â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 12133833 16189514 21988832 25861989 20484576 33961781 17468758 30561431
BCL10 AKT1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16280327 24462114 24412244
BCL10 NEMO â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 11113112 17363905 14695475 27070702 23690623 19897484 27777308 18287044 15184390
RIPK1 TRAF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25416956 24735611 23972990 16603398 8612133 32296183 16291755 11181075 19815541 24434549 30561431 21810480 11479302 31502302 27768232 20577214 25716317 21282461 25882049 8702708 9020361 16713569 29352166 23007157
RIPK1 NEMO â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24735611 10755617 17702576 26740240 21606198 14653779 16603398 16543241 21113135 16547522 26865630 10980203 23746843 30561431 11262391 32024692 19373245 18029035 31502302 21458669 10880512 18212736 22099304 28249776 21383699 26802121 23104095 27929056
IKKB TRAF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32024699 20449947 21782231 16713569 25241761 27387502 19150425 23007157 11359906 18362886
M3K14 TRAF2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 9020361 15084608 16189514 23543740 16713569 20184394 25416956 31980649 9275204 25246529 20348096 20385093 11278268
TRAF2 IKKA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20449947 25241761 16713569 23007157 19150425 11359906 9244310
NCOA3 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19305643 12650696 17671194
IKKB NFKB1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 25241761 16713569 11297557 11976329 10469655 11158290 22536447 12482991
NFKB1 IKKA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14743216 16713569 11297557 11976329 10469655 25609649 12482991
NFKB1 NEMO â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14743216 27609421 15043934 35140242 25609649
NEMO IRAK1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24735611 21220427 23986494 18180283 23104095 18347055 17997719
M3K14 NFKB2 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14743216 31980649 17563756 11239468 32707033 30833792
IKKB NCOA3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15383283 16051665 16135815 11971985
NCOA3 IKKA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15808510 15383283 16051665 11971985
CBP P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22084066 23908595 27618436 19234109 20962272 14759370 10551785 18485870 19166313 10473588 12426395 12154097 18753379 14722092 19357310 10848610 28630323 10648616 19880525 25314079 9194564 15632413 16537920 17434128 10196247 10823891 26976603 25451029 19220000 16713569 21390126 19805293 9288775 11782467
E2AK2 P53 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 10747897 10348343 19631745 10884347
P53 HS90A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32097779 16189514 15358769 16713569 21268072 23443559 31152661 11297531 21460846 15004035 22939624 30911017 11507088 11707401 15001357 10557093 12427754 32807901
IKKB IKBB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14743216 9346485 33961781 9721103 9689078
M3K14 NEMO â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 14743216 16189514 31980649 33961781 32707033 9927690 30833792
NEMO IKKB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 23986494 20211142 16611882 20098747 15802604 30913450 16547522 14743216 18450452 10980203 19666608 23131831 21455180 16906147 15184390 24469399 19820708 18462684 31145594 15749833 28249776 24618592 10968790 19422324 30500824 23104095 16938294 31932854 18949366 20167598 16603398 25286246 18583959 24266532 22605335 27426725 26500060 19706536 19365808 18037881 20932476 30404796 16319058 9751060 23506214 25979343 17363973 25400026 22990857 12657630 30561431 12459277 12486103 16583354 29474632 32024699 11971985 11057907 18266467 12133833 24240172 18266324 23016877 21423167 17977820 33961781 20368414 32731169 28514442 25304104 18207244 12612076 19959994 25852190 21903422 29111346 26496610 19656241 17000764 21803029 16497931 20434986 16129692 17568778 11864612 22099304 19815509 17693255 27929056
M3K14 IKKB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 14743216 10733566 9346485 9520446 33961781 10195894 32707033 16286467 30833792 11278268
IKKB IKBA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 18202307 11080499 19345327 9914500 26740240 12709429 9346485 16611882 32555320 18723677 22904686 9520446 19959994 12054687 23816567 14743216 16365431 16291755 27497262 27387502 17363905 12624112 18539148 15125833 29650758 28214532 9751059 22990857 26221961 15919917 15125834 18375836 18593939 12486103 19196987 24469399 22037600 25595906 30254148 21399639 22022389 17079871 24912152 15456896 18981174 16286467 12411322 9689078 20434986 12943667 20449947 24618592 25759022 21423167 20797629 15218148 18519641 15217903 24611898 26802121 29958295 16319058 9721103 9891086 21765415
IKBA IKKA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 11042193 17053167 11080499 9914500 9346485 18949366 9520446 15590691 16354686 19959994 12054687 14743216 10733566 17363905 12624112 10094049 24270572 11809792 11940602 9751059 17379600 11113112 12486103 23602409 32912968 15670770 18922877 18003900 17384642 10066434 18074035 18501560 15389589 9252186 16286467 12190313 12411322 9689078 20434986 15310755 20449947 24618592 16219905 12138192 20932476 16493072 11095741 20133937 18519641 29958295 33961781 12730857 26186194 16319058 9721103 9244310 21765415
IKKA TF65 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14743216 8246997 21903422 22689577 18519641 32232831 12842894 16382138 17434128 16046471 15489227
M3K14 IKKA â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 14743216 15084608 25241761 32707033 31980649 10094049 9520446 20348096 15208311 33961781 17563756 9244310 16286467 30833792 11278268 10887201 16498412
IKBA ELP1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 14743216 9751059 32912968
AKT1 MTOR â—¼   PHYSICAL_INTERACTION 905.0 0.9 STRING 36370105
TRAF2 RIPK1 â—¼   UP_REGULATES ✅ + 0.9 0.9 Signor 10795740
TRAF2 RIPK1 â—¼   UBIQUITINATION ✅ + 0.9 0.9 Signor 18621737
AKT1 ARRB2 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 18191226 19122674 19262695
RIPK1 TRAF2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
MTOR AKT1 â—¼   PHOSPHORYLATION ✅ + 0.92 0.92 Signor 21592956
CBP IKKA â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 17434128 14597638 11971985 12789342
IKBA NFKB2 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 14743216 32912968 26496610 33961781 26186194
NFKB2 IKBB â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 14743216 33961781 26186194
SRC CTNB1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 23246962 11279024 22056988
AKT1 HS90A â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 32707033 16189514 21767636 12176997 31980649 25714412 15843522 29311840 22504172 16027165 29139175 12586360 19356729 10995457
NFKB2 IKKA â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 14743216 15140882 17962807 16651533 16303288 21131783 17563756
IKBA IKBB â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 22081069 14743216 28514442 33961781 26186194
M3K7 CDC37 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 14743216 31980649 19026643 33961781 32707033
IKKB KEAP1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 24322982 19818716 27387502 30126895 25926686 30500824 24127568 20600852
NFKB1 IKBB â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 28514442 14743216 27609421 35140242 33961781 26186194
NCOA3 CBP â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 9267036 16713569 11971985 17043108 16227615 9346901 15383283 11823864 9445475 21632823 33589584 9192892 8616895 26267537 11076796 21914189
CBP CTNB1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 26123998 16476742 33190089 11973335 23273993 19223551 28648376 30836930 18347063 26657156 21751375
P53 IKBA â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16189514 32912968 16713569 11799106 15969767
IKBA NEMO â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 21811235 19959994 16547522 22081069 14743216 26865630 23732909 11830587 21896478 23746843 26496610 17363973 21217772 15670770 18429822 32246052 15749833 15218148 18519641 18957422 16319058 21862596 11064457
M3K7 HS90A â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 32707033 14743216 19026643
CDC37 HS90B â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25036637 28215707 24189400 23428871 26496610 22939624 33961781 27339980 11036079 25486457
CDC37 HS90A â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 24292678 24462205 22939624 14718169 15647277 16335536 21871133 25036637 26496610 21745565 25486457 12176997 22729780 24189400 22504172 22315411 26804907 11413142 12930845 20159553 15001580 19875381 27353360 9685350 33961781 16611982 21360678
TANK TRAF2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 14743216 16189514 16713569 21988832 20562859 10581243 23007157 12005438 33961781 8710854 10759890 28155233 30561431 21903422
NFKB1 TF65 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 20547752 8255759 27609421 29439025 16740634 21988832 24634218 14645533 11970949 35140242 15799966 25609649 15660126 21544861 29084252 14743216 8246997 34100597 22139845 17962807 9722548 2050119 22808155 20154269 21270162 17982102 24175631 25355951 23687337 11976329 15657065 8428580 20237821 12414801 10498867 22261743 16204234 16105840 14690596 11880271 33060567 8798655 16319923 21483817
NFKB1 IKBA â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 20558726 7891711 27609421 29439025 21988832 7739549 16210649 8631829 35140242 25609649 17003112 9566883 14743216 26496610 8887676 22536447 32912968 9572494 9865693 33572115 20237821 9738011 11313474 20980497 33961781 11020244 26186194
NFKB1 NFKB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 14743216 27609421 21988832 17962807 15169888 35140242 25609649 15660126
TF65 NFKB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 14743216 27609421 17962807 16009713 8413211 16940413 29084252
CBP TF65 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 12163591 15140884 16291753 14597638 17362989 17962807 18241676 17296604 9096323 12789342 25314079 9548485 11931769 9806899 10542243 17434128 25733689 15806143 16713569 10235267 10454579 17138826 21483817 9659924
IKBB TF65 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 14685242 14743216 16189514 22081069 28514442 27609421 21988832 33961781 8887627 8816457 26186194 12672800 10498867
NEMO IKKA â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 11080499 21703539 23986494 16611882 25304104 20098747 18949366 18207244 11877453 30913450 12612076 19959994 21903422 22605335 14743216 10733566 10980203 22547678 19666608 23131831 26496610 17363973 21455180 22990857 12244103 26500060 18079694 30561431 12459277 17000764 15184390 12486103 16583354 24469399 18462684 11485410 25355947 11057907 32707033 16497931 15749833 20434986 18266467 32935379 17568778 11864612 17244613 24618592 28249776 23016877 12138192 19815509 17977820 10968790 20368414 30404796 33961781 16938294 16319058 9751060 17728323 27929056 32731169
IKKA IKKB â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 28514442 25241761 11080499 9914500 9346241 9346485 11585904 21784860 25852190 25748427 12210728 21903422 14743216 10733566 12244103 9346484 12486103 11971985 21575199 11057907 32707033 16286467 16129692 20434986 11864612 16713569 23016877 20932476 10968790 30500824 17693255 33961781 9751060 16319058 9721103
HS90A HS90B â—¼   PROTEIN_INTERACTION 0.98 0.98 HIPPIE 25036637 31536960 20353823 26496610 22863883 26344197 33961781 21360678 19875381
TF65 IKBA â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 14685242 28514442 27609421 29439025 21988832 7739549 24634218 23850221 11533489 23185316 15799966 30628021 17003112 16951195 8887633 25520503 20065107 9566883 16683270 22081069 14743216 8246997 17612295 11287411 20551178 23563313 29084252 8657102 9694722 11231305 9057089 26496610 17301240 21217772 33754058 9751059 29734393 20876301 30213788 24457201 32912968 12419806 25609694 26476452 22022389 9572494 15657065 9865693 10066434 9738011 10085161 8978697 24248593 10498867 27923823 30542119 11313474 19219072 16105840 14690596 25759022 20797629 33060567 20980497 33961781 11020244 8887627 8139561 26186194 26463447 9990853 33478005 7878004 7628694
MTOR MYC â—¼   ENZYMATIC_REACTION ✅ 23.0 1.0 ACSN 12150925 12408816 12906785 15755954 16469695 17604271 17680028 18372248 18492954 19022819 19446321 19568798 19706736 19864431 21157483 21981924 23087689 24795729 24973821 25002027 25730849 26159692 28216025
MTOR AKT1 â—¼   ENZYMATIC_REACTION ✅ 45.0 1.0 ACSN 10722653 10949026 11274345 11715018 11756412 11756498 11923280 12408816 12906785 15169778 15808505 16469695 16697215 17052453 17461779 17680028 18000759 18372248 18492954 18570873 18636226 18925875 19022819 19143635 19151919 19568798 19720745 20027184 20138985 20214616 20338997 20398329 20832730 21157483 21474067 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9812896
MTOR AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 20338882 17517883 18372248 19203586 27418134 17277771 15718470 26491696
MTOR AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 80.0 1.0 Omnipath 18000759 20027184 21157483 11756412 11923280 24670654 16697215 11438723 21592956 20398329 17461779 18372248 21177249 21045808 20338997 15808505 16221682 20138985 20489726 15899889 20214616 8978681 21474067 14970221 19203586 17660512 15718470 19568798 20333297 23006971 15169778 25241761 18566586 19720745 17517883 18925875 22084251 10949026 14761976 11715018 19143635 17277771 18636226 10910062 15047712 9812896 18505677 21343617 19844585 17680028 19151919 18566587 9736715 23872070 10722653 20832730 18570873 17013611 17052453 12408816 15364915 11274345
NFKB1 MYC â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 18490439 19219071 21725609 2191300 23178297 23572150
NFKB1 MYC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 12894581 18184402 7869034 17673602 12783888 11114727 17944672 9596659 12504005 19469019 21790895 19766095 17018379 8289784 18566231 1515224
TANK TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 20562859 21988832 21903422 8710854 12005438 14743216 10581243 16713569 23007157 10759890
TRAF2 RIPK1 â—¼   PHYSICAL_INTERACTION 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
TRAF2 RIPK1 â—¼   SHARES_COMPLEX 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
TRAF2 RIPK1 â—¼   ENZYMATIC_REACTION ✅ 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
TRAF2 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 8702708 8612133 25416956 16713569 18621737 25882049 16291755 18981220 21741934 21232017 20577214 11181075 10795740 23972990 21119000 15175328 20203691 21810480 21282461 9712898 32296183 23007157 25716317 20448643 12887920 24735611 15258597 24434549 19815541 16603398 11479302 9020361
NFKB1 TRAF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15723831 15041463 19392652 18990758
SRC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11445557 25241761 23242524 18283331 12600984
AKT1 IRAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11976320
AKT1 AKT2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 11546794 14500673 12176337 11445557 9736715 12149249 11278835