Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
NFKB1 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 18031796
NCOA3 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16877447 20305690
SUMO1 ATM â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 20023648 22508508
BIRC3 BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23070005 18485876
NFKB1 BIRC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9294162 9733516
BIRC3 RIPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 21931591 19464198
CDC37 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CYLD RIPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 19131965 23010170
RIPK2 CYLD â—¼   DEUBIQUITINATION ✅ 2.0 0.8 Reactome 12917691 15620648
UBC CYLD â—¼   DEUBIQUITINATION ✅ 2.0 0.8 intact 19373254 7288828
CYLD RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 17981138 19131965
IRAK1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218906 16884718
MALT1 TAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17948050
MAVS UBB â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
MAVS UBC â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
NFKB1 RIPK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19693652
SUMO1 NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18617892 6804701
PRKDC NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBB NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TNIP2 NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBC NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18617892 6804701
PARP1 NFKB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PARP1 TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PARP1 TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
PARP1 UBC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7986053 19779455
SUMO1 PARP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19622798
RNF31 TAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 16260783 16953224
UBC SRC â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6504434 17936276
TANK SUMO1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 21212807 8142110
UBB TAB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF2 TANK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
TRAF2 TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBC TBK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18636086 6804508
UBC TNIP2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19373254 7288828
TNIP2 UBB â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
UBB TRAF2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
UBB TRAF6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 14743216 5216883
CYLD UBC â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
CBP SRC â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 22364282 15615775 16713569 16860316
SUMO1 IKBA â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 9734360 10085161 19625650 23604351 23284737
MALT1 TRAF2 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 15125833 19234489 16713569
TAB2 UBB â—¼   PHYSICAL_INTERACTION 813.0 0.81 STRING 36370105
NEMO ZPR1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NFKB1 HSP71 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 14743216
TNAP3 SQSTM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33545068 28574503
CACO2 SQSTM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33545068 21079414
SQSTM PARP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 28796254 31536960
RB6I2 NEMO â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20932476 15218148
IKKB RB6I2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20932476 15218148
F196A NEMO â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
T2EA NEMO â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 20211142
SYNCI NEMO â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
FKBP5 NEMO â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 25036637
NEMO CACO2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21988832 33815386
NEMO SDCG8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NEMO CENPF â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NEMO KEAP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20600852 30500824
IKKB FKBP5 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 21903422
CNTN2 IKKB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16424386 17891179
IKKB CSN3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 19656241 23636414
IRAK1 IKKB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18180283 11096118
F196A IKKA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
IKKA RIPK1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 10980203 29955050
BCL10 IKKA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 14695475 22547678 11113112
CNTN2 IKKA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16424386 17891179
IRAK1 IKKA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18180283 11096118
IKKA KEAP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20600852 30500824
PARP1 TRI29 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20211142 26381412
SYNCI M3K7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
M3K7 MALT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17948050 25748427
SHRPN MALT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33329596 27070702
TNAP3 CACO2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30561431 33545068
TRAF6 CACO2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21988832 33815386
SYNCI CACO2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TNAP3 SRC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
TNAP3 UBB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SYNCI TNIP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RIPK1 HS90B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939624 14743216
CYLD K2C8 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27591049 34079125
BIRC3 SUMO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21988832 30948266
EGFR CNTN2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31980649 20029029
MAVS CYLD â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30410068 18636086
CYLD TAB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27591049 31762063
EGFR PARP1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24780295 28065597
EPAS1 SUMO1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20026589 20661221
TAB2 MALT1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 17948050 25748427
NFKB1 PRKDC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 25609649 14743216
NFKB2 UBC â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 18617892 14743216
RNF31 UBB â—¼   PHYSICAL_INTERACTION 823.0 0.82 STRING 36370105
INHA NEMO â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NEMO CBP â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 14597638 11971985
RIPK2 TNR1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 9642260 16189514
TNR1A BIRC3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19815541 30420664 18939944 15310755
TNR3 NEMO â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
ZFAN5 NEMO â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 14754897 16189514
UBP10 NEMO â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24270572 25861989
PPM1B NEMO â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 14585847 16189514
TP4AP NEMO â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16189514 14585990
TNFA NEMO â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27307491 26670046 30561431 27560715 30420664 34315543 16603398 33815386 20005846 23104095 23032187 23032186
TPM1 NEMO â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
NEMO TRI29 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 20211142 27695001
NEMO CNTN2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16611882 16424386 17942533 19064727 17891179 33362245
NEMO SNW1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 32805409 32296183 20211142
TP4AP IKKB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 32889079 14585990
PPM1B IKKA â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 14585847 25241761
IKKA TANK â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 12133833 30561431
TRAF2 CIKS â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 30892082 15485634 16713569 21822258 16189514
BIRC2 M3K14 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 18022362 25246529 20184394
MALT1 CAR11 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23322406 22528498 33329596 17948050 25748427 31961340
TNR3 SHRPN â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
KEAP1 HS90A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24127568 20864537 26517842
TRAF2 CACO2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 16189514 16713569 33545068
RNF31 TNAP3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 23032186 27545878 30561431 23032187
TNAP3 TBK1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 19615732 30561431 15661910 21885437
TBK1 HS90B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22939624 14743216
TRAF2 HS90B â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25241761 14743216
TNR3 HOIL1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TNR3 RNF31 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TNR3 UBB â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
BIRC2 BCL10 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 16775419 10753917
TANK BIRC2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 30561431 23524849 21903422
BIRC2 RNF31 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 24726327 27545878 30561431 23524849
TRAF6 BIRC3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 20097753 24464131 23524849 29545793
CDC37 FKBP5 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 25036637 24981860
RIPK1 CYLD â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33654169 22848449 28900035 17981138 21408173
RNF31 CYLD â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 27307491 26670046 27591049 27458237 28189684 27545878
NFKB1 TNIP2 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CYLD TRAF6 â—¼   PHYSICAL_INTERACTION 833.0 0.83 STRING 36370105
BCL10 BIRC3 â—¼   PHYSICAL_INTERACTION 839.0 0.83 STRING 36370105
CBP IKKB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25241761 14597638 11971985
TBK1 SQSTM â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 27035970 31810986 32835772 25972374 33545068
NEMO TNR1A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 30561431 30420664 27552911 10755617 16189514
MAFIP NEMO â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 21109981 21988832
RB11B NEMO â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 26496610 11495908
BIRC3 NEMO â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 18931663 23524849
NEMO AKT1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20837477 20098747
NEMO RPAP3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20098747 21184742
IKKB HS90B â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25241761 14743216
SRC IKKA â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15749833 12707358
M3K7 UBC â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16845370 19820695
M3K7 HS90B â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 32707033 14743216
IKBA UBC â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 18539148 17318178
NFKB1 HS90B â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25609649 25241761 14743216
BIRC2 TNR3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12571250 28514442 26186194 33961781
TANK ZC12A â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 25861989 16189514
IRAK1 CDC37 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15647277 32707033
CYLD RIPK1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
PRKDC PARP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20085707 16794079 21575865 9398855
RIPK2 TRAF6 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 18329614 9642260 21097508 16189514
TRAF2 TAB2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 19150425 17384642 14633987 10882101
BIRC3 TRAF6 â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
UBB UBC â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
BIRC2 UBB â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
CYLD RNF31 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
RIPK1 TAB2 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
AKT1 CBP â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 19995607 23434580
SUMO1 NEMO â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 20932475 16906147 21811235 21212807 14651848 16360037 21777808 18583959
TNIP1 NEMO â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 30561431 18212736 21988832 20010814
MAVS NEMO â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 23028469 24379373 20161788 21903422
NEMO ATM â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 32731169 16497931 20065354 30254148 18583959 28202068 24457965
NEMO FADD â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 21458669 30561431 16227629
NEMO UBC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 17363905 16874300 19373254 14743216
NEMO M3K7 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 32731169 17363973 21606198 33139544 23986494 19531477 30404796 34535633
NEMO TAB2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 17626013 21988832 23986494
PPM1B M3K7 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 11104763
M3K7 CYLD â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 29291351 18332137 27591049 32410369
SRC IKBA â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 33961781 12429743 9792645 26186194 8797825 28514442
TNFA SHRPN â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 27307491 26670046 27458237 27560715 30561431 23955153 30420664 32968279 31898971 23104095 27545878 23032187 23032186
HS90A IRAK1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 15647277 32707033
TNFA RNF31 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 27307491 26670046 30561431 23955153 30420664 24726327 32968279 23732909 31898971 33815386 20005846 27545878 23746843 23032187 23032186 32019898
TNFA HOIL1 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 27307491 26670046 25911380 23955153 30420664 31898971 20005846 27545878 23104095 23032186
TNFA TNAP3 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 27307491 26670046 30561431 25911380 22099304 32968279 32599618 27545878 23032187 23032186
HS90B SRC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 28215707 32707033 31980649
TAB2 TRAF2 â—¼   PHYSICAL_INTERACTION 851.0 0.85 STRING 36370105
NEMO PP1G â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24586659 14743216
PP1G ACTG â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 21382349 26496610
M3K14 HSP71 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14743216 31980649
TAB2 HSP71 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 14743216
M3K7 HSP71 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 14743216
RIPK1 HSP71 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 14743216
HS90B HSP71 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 16263121 22939629
TRAF2 NEMO â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28249776 23007157 31502302 10980203 12867425
SRC NEMO â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23131831 15749833
ZC12A NEMO â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24270572 25861989
NEMO PRKDC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31932854 14743216
NEMO CAR11 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17363905 18625728 16301747 15184390
NEMO ACTG â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 30561431 14743216
NEMO MALT1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 27070702 18212736 17948050 18931663 19494296 25748427
NEMO BIRC2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 30561431 20932475 23732909 23524849 12867425 22990857
NEMO CCAR1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28514442 14743216
NEMO UBP18 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26240016 14743216
BCL10 IKKB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19118383 14695475 11113112 17213322
SRC IKKB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 15456896 15749833 12645577 12707358
CIKS IKKA â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10962033 12943667
IKKA HS90B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 14743216
SHRPN TNAP3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23032186 30561431
UBP10 ZC12A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24270572 25861989
TAB2 HS90A â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14743216 19875381
TNAP3 HOIL1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23032186 23105109
MCM7 HS90B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22863883 23764002
ATM PRKDC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10464290 10608806
BIRC3 BCL10 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 16775419 11466612 10753917 16395405
NFKB2 SUMO1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24654937 18617892
SUMO1 PARP1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 19779455 15561718 23871147 15576338 19596686
TRAF6 SRC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22447928 10635328 16189514 29545793
AKT1 CDC37 â—¼   PHYSICAL_INTERACTION 869.0 0.86 STRING 36370105
SQSTM NEMO â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 29255244 16874300 24270048
EGFR TNR1A â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 31980649 25402006 24658140
TNR1A UBB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 14743216
K2C8 NEMO â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20098747 21988832
NEMO MCM7 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20098747 14743216
NEMO SENP2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20098747 21777808
NEMO PARP1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 14743216 25735744
NEMO PP2AA â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16129692 16126728
NEMO UBB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 28514442 14743216
PP2AA IKKB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 16129692 16126728
M3K14 M3K7 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10807933 10094049
RIPK1 M3K7 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 21606198 18570872 16543241 24434549
UBB CACO2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 28514442 25416956 33961781
TNAP3 RIPK1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 15258597 18246070 30561431 19131965 29274253 22585859 32015333
PARP1 NFKB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25609649 16799643 16204234 11590148
TRAF6 TRAF2 â—¼   PHYSICAL_INTERACTION ✅ 0.87 0.87 mint 8153045 21516116
TRAF2 TRAF6 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MAVS TRAF2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
MALT1 TRAF6 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
BIRC2 TRAF2 â—¼   UBIQUITINATION ✅ - 0.87 0.87 Signor 20651737
TNIP1 UBC â—¼   PHYSICAL_INTERACTION 879.0 0.87 STRING 36370105
CBP SUMO1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23395904 28630323 27129204
PP1G RPAP3 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 30344098 28330616 28561026 26186194 24366813 28514442
SQSTM IRAK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12034707 10747026 34079125
NEMO IKBB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 11485410 14743216 21862596
EPAS1 NEMO â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26500060 15653678
CSN3 NEMO â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16189514 11418127
RIPK2 NEMO â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18079694 16189514 10880512
NFKB2 NEMO â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 21131783 14743216
NEMO A16L1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 29634390 14743216
NEMO RB11A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26258637 18685082 17030804
NEMO HS90A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 26496610 14743216 11864612 19875381 16189514
IKKB HS90A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11864612 19786027 14743216
CIKS IKKB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 10962033 12943667 24561578
IKKA HS90A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 22384180 14743216 11864612 19875381
FKBP5 IKKA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 25036637 14743216
TP4AP TRAF2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 16713569 16189514 16876162 14585990
M3K7 FKBP5 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 32707033 14743216
RB11A RB11B â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 22939629
M3K14 TRAF6 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 9275204 16189514 16286467 25241761 10921914 11278268
MCM7 IKBA â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 32912968 14743216
RIPK1 HS90A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 14743216 22939624 16968706 10744744
HS90A TBK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 22939624 20628368 14743216 16394098
TRAF2 ACTG â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 30561431 25241761 14743216
CACO2 MAVS â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33577621 31304625 21903422
TNFA RIPK1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26670046 22099304 30420664 12753742 32968279 22675546 16603398 23104095 27545878 21331077 24980434 23032187 27307491 12887920 27458237 33469115 25911380 34315543 32599618 22028622 23955153 24726327 31898971 20005846 21620750 27560715
TNFA BIRC2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 27307491 12887920 21822306 25911380 30561431 32968279 20005846
CDC37 AKT1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 31980649 24869908 22504172 12176997
BCL10 TRAF2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33961781 11466612 32296183 25910212 10753917 16713569 25416956
BIRC3 RIPK2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 19464198 9705938 21931591
TBK1 CYLD â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18636086 25923723 29755980
TBK1 MAVS â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 33372174 24643253 21903422 32511263 21813773 25636800 23028469 29125880 28346439 32366851 29743353 16153868
NFKB2 TNIP2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 27609421 14743216
MAVS TBK1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
IRAK1 TAB2 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
BIRC2 RIPK1 â—¼   PHYSICAL_INTERACTION 889.0 0.88 STRING 36370105
NEMO HSP71 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11877453 16189514 14743216 16713569
RIPK1 SQSTM â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 26416459 32707033 10356400
TRAF6 SQSTM â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23911927 16874300 20974803 23017601 28244869 11244088 26279575 30281815 32265222 17389358 15870274 27458013 27681126 32384667 15340068 19201866 16189514 10747026 31281713 19903815
IKBB IKKA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 9689078 14743216 11485410 9346485 9252186
SUMO1 TNR1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10187798 8906799 16189514
TP4AP TNR1A â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20458742 16189514 14585990
TNR1A IKKB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31406107 21331078 11002417 21724995 30420664 25241761 10755617 11821416 18949366
TNR1A BIRC2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 19815541 30561431 25681446 30420664 32968279 18022363 8943045
EGFR NEMO â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
NCOA3 NEMO â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16051665 11971985
TNIP2 NEMO â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30561431 21988832 14653779
CYLD NEMO â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12917689 30561431 31366726 12917690 26802121 16627981 21988832 12917691 15341735 22990857
CIKS NEMO â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10962033 12943667 16189514 10962024
NEMO RNF31 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33215740 24469399 21455180 28249776 30561431 21811235 23732909 23986494 33815386 30913450 26577923 23032187 23032186 29650758 19675569
NEMO TRAF6 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18617513 25400026 25548215 28249776 20932475 15125833 17135271 27695001 23986494 30254148 18180283 20529958 17728323 30404796 24270048 27929056 28214532 30913450
NEMO HS90B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26496610 24618592 14743216
NEMO SHRPN â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21455180 27893701 28249776 30561431 23986494 21709223 33815386 30913450 23032186
IKKB TNAP3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21220427 26649818 11594795
M3K7 IKKB â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31127032 10779355 10807933 10195894 24270572 27693634 33895773 17363905 11460167 17363973 9689078 10022904 18316610 34535633 32410369 25946971 21331078 20932476 18456659 26334375 27387502
M3K7 IKKA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10187861 16893890 9742107 25241761 20200282 10094049 33895773 34535633
AKT1 IKKA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10485711 25241761 15710601 11278366 10485710 17962807 15800029
TRAF2 M3K7 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 14743216 17384642 26299341 14633987 32024699
HS90A M3K14 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 30833792 31980649 14743216 17563756 22939624 32707033
M3K14 HS90B â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22939624 32707033 14743216 31980649
M3K14 CDC37 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25036637 30833792 31980649 14743216 32707033
SHRPN HOIL1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 34518544 21455181 26670046 21455180 30561431 33329596 28978479 33392484 24726327 31067453 30804189 23032186
HS90A SRC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16844778 22315411 31980649 28537252 1310678 32707033 16189514
TBK1 CACO2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 30309841 21903422 19820708 28514442 32707033 33545068
TRAF2 TNFA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 27307491 12887920 21822306 25911380 30561431 15485837 23955153 30420664 32968279 16603398 20005846 27545878 24980434
TRAF6 TNAP3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20622874 21220427 18164316 28244869 23737552 9928991 29720226 15334086 23018911 23105109 31625129 11463333 32015333
TNIP1 TNAP3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18029035 30561431 32296183 11389905 12586352 10385526 21988832 16713569 25165885 25416956 12965196
TNIP2 TNAP3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 18029035 30561431 11389905 15169888 21266526 11390377 10385526
HS90B AKT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 20650008 31980649 10995457
EGFR AKT1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 31980649 25402006 24658140
RIPK1 BIRC2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 29021293 23972990 30561431 26612615 21931591 19854138 21113135 18570872 27197231 29955050
RIPK2 BIRC2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 16189514 21931591 19464198 9705938 30026309 9642260
RIPK1 BIRC3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23972990 21931591 21113135 18570872 33526051 16547522
EGFR CDC37 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 25036637 31980649 23956138 24189400 12471035
TAB2 IRAK1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 23986494 24735611 18180283 12242293 11518704 19675569
RIPK2 TRAF2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21903422 9705938 16713569 32707033 16189514
TANK TRAF2 â—¼   PHYSICAL_INTERACTION 895.0 0.89 STRING 36370105
TBK1 TRAF2 â—¼   PHYSICAL_INTERACTION 897.0 0.89 STRING 36370105
EGFR HSP71 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15657067 24658140 31980649 25241761 25402006 20029029 24189400
HS90A HSP71 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12093808 27353360 12853476 11413142 16263121 19875381 24949977 21360678
KEAP1 SQSTM â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33603948 26043024 32075457 21482715 25505069 28617433 28416489 27554286 30581152 20495340 23242280 30126895 27631370 23117207 20421418 20173742 31169361 33545068 32296183 19615732 24011591 28820283 23795962 25416956 25939382 20378532 28846113 24322982 28380357 20562859 25910212 30907226 33397898 34079125 20452972 29033244
SQSTM CDC37 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 32296183 20562859 21900206 24189400 34079125
IKKB IKBB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 9689078 14743216 9721103 9346485
TNFA TNR1A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24070898 33961781 26670046 8288897 22099304 30420664 12753742 32968279 22675546 33815386 27545878 23032187 8182064 24980434 9488135 2848815 27307491 11448951 12887920 33469115 25911380 9568681 2170559 34315543 8805640 1310388 22028622 20080539 10634209 23955153 24726327 31898971 14743216 28514442 19084540 27560715 15485837 2158863 15173183 25241761 20103630 2170974 26186194 22801493 23746843
RIPK1 NEMO â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21458669 26865630 22099304 11262391 19373245 16603398 21113135 23104095 18029035 21606198 18212736 10880512 28249776 30561431 16543241 21383699 17702576 31502302 24735611 26740240 26802121 27929056 16547522 10980203 32024692 10755617 23746843 14653779
CDC37 NEMO â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25036637 26496610 14743216 11864612 24618592 24189400
NFKB1 NEMO â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 35140242 27609421 14743216 15043934 25609649
TANK NEMO â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12133833 33961781 30561431 20484576 25861989 21988832 17468758 28514442 16189514
BCL10 NEMO â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17363905 27777308 27070702 18287044 19897484 14695475 23690623 15184390 11113112
M3K14 NEMO â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 30833792 31980649 14743216 9927690 28514442 32707033 16189514
NEMO IRAK1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21220427 23986494 24735611 18180283 17997719 23104095 18347055
NEMO TNAP3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 30561431 11389905 22099304 33139544 26802121 10755617 21988832 23032186 31585000
NEMO TBK1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 30561431 21903422 26611359 14743216 20098747 23028469 28514442
NEMO HOIL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 21455180 27893701 28249776 21811235 23732909 21709223 23986494 33815386 20098747 30913450 23032186 19675569
NEMO IKKB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20211142 9751060 16497931 29111346 19656241 27426725 19820708 17977820 23986494 12657630 24240172 32731169 16129692 27929056 25304104 28514442 11057907 32024699 19666608 12612076 17693255 18949366 29474632 22099304 10968790 19959994 26496610 16603398 20098747 26500060 31145594 18266467 25286246 19706536 16319058 12459277 20932476 25979343 24469399 19815509 18037881 22990857 21803029 17363973 16583354 24618592 25400026 19365808 21455180 25852190 30404796 16547522 16611882 20167598 20368414 18450452 33961781 19422324 30913450 23104095 20434986 18266324 16906147 18462684 11864612 15749833 17568778 12486103 23131831 31932854 30500824 15802604 12133833 28249776 30561431 14743216 23016877 11971985 17000764 15184390 23506214 10980203 24266532 21423167 16938294 21903422 22605335 18207244 18583959
IKKB IKBA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24469399 18202307 16286467 25595906 18723677 19959994 26221961 32555320 11080499 15919917 9520446 15456896 28214532 20434986 27387502 15218148 22904686 22990857 17363905 12054687 9751059 15125834 15125833 9689078 24611898 21765415 12709429 20449947 12943667 23816567 24618592 27497262 18593939 9346485 16291755 12486103 24912152 22037600 20797629 15217903 25759022 18519641 14743216 16319058 26740240 26802121 22022389 19345327 9721103 12624112 12411322 21423167 18539148 16611882 9891086 16365431 19196987 21399639 9914500 17079871 29958295 30254148 18981174 29650758 18375836
IKKB NCOA3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15383283 16051665 16135815 11971985
CDC37 IKKB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25036637 21903422 26496610 14743216 11864612
M3K14 IKKB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 28514442 33961781 30833792 16286467 14743216 10195894 9520446 9346485 10733566 32707033 11278268
IKKB NFKB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12482991 25241761 22536447 11158290 16713569 11297557 11976329 10469655
IKKB TRAF2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23007157 19150425 25241761 20449947 11359906 18362886 16713569 21782231 27387502 32024699
TRAF2 IKKA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23007157 19150425 25241761 20449947 11359906 16713569 9244310
NCOA3 IKKA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15383283 16051665 15808510 11971985
CDC37 IKKA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 25036637 21903422 14743216 11864612 24189400 32707033
IKBA IKKA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 16286467 15310755 19959994 18074035 11080499 11095741 10066434 9520446 12138192 17384642 24270572 9244310 20434986 12190313 10733566 12730857 17363905 11809792 9751059 12054687 17379600 9689078 32912968 21765415 20449947 18501560 24618592 15670770 9346485 12486103 18519641 11042193 14743216 16354686 16319058 9721103 28514442 16493072 12624112 16219905 18003900 15590691 12411322 20932476 18922877 11940602 20133937 23602409 9914500 26186194 29958295 10094049 18949366 15389589 17053167 11113112 9252186
M3K14 IKKA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 20348096 30833792 31980649 16286467 15208311 14743216 16498412 15084608 10887201 25241761 9520446 17563756 10094049 9244310 28514442 32707033 11278268
NFKB1 IKKA â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12482991 14743216 25609649 16713569 11297557 11976329 10469655
M3K7 TRAF6 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31127032 16543409 22851693 11518704 21822258 27249171 12242293 31885808 19843958 22643835 19112497 33768585 28024152 12609980 10921914 11259596 19521662 10882101 16517750 14633987 18758450 12496252 31404116 22924441 24434549 19232515 26038599 10094049 19820695 27501752 25963657 19675569
M3K14 TRAF2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20348096 9020361 20385093 9275204 16189514 25416956 31980649 23543740 15084608 20184394 16713569 25246529 11278268
M3K14 NFKB2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 30833792 31980649 14743216 17563756 11239468 32707033
CAR11 BCL10 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25548215 22528498 27777308 11356195 18625728 19444310 30279415 16356855 21513986 17948050 24074955 19118383 21157432 23690623 18806265 11278692 19815501
SHRPN RNF31 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21455181 26670046 33329596 23104095 27545878 30804189 22253853 22158122 27307491 34518544 32122970 31067453 23032186 21455180 27591049 30561431 28978479 33392484 24726327 28514442 33215740 26600301 24141947 28775156 22791023 23746843 32019898
FKBP5 HS90A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25036637 20048054 10642522 12538866 28363942 9001212 21170051 20661446 21235734 19875381 22863883 23999428 21360678 29079741
EGFR HS90A â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24658140 31980649 23956138 20029029 12006493 25402006 16849543 16024644 24189400 12471035 32669362
HS90A RPAP3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25036637 24794838 21360678 19875381
FKBP5 HS90B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25036637 21170051 30382094
EGFR HS90B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15657067 24658140 31980649 24189400 23956138 25402006 20029029 22939624 12471035
RNF31 HOIL1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 21455181 26670046 33329596 23708998 27545878 26577923 26264872 23032187 22430200 27307491 34518544 32814053 32122970 21455180 30561431 28978479 24726327 20005846 28514442 17006537 29892012 33215740 17069764 24141947 26525107 22791023 32019898 29997244
BCL10 AKT1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24412244 16280327 24462114
ATM AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15546863 15899889
TRAF6 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 34938598 19713527
MALT1 BCL10 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 22528498 27777308 33329596 25569716 22658522 11262391 11090634 17189706 22267217 27071417 18806265 27113748 31961340 19279678 24130731 30279415 25748427 29953499 21513986 19118383 23690623 25548215 27070702 19444310 17948050 14695475 21157432 31774199 20551178
BCL10 TAB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 17158449 15327770 10882101
NFKB1 BIRC2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 21725609 23178297 23572150
CDC37 SRC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 32707033 31980649 11085988
TRAF6 MAVS â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31390091 21903422 32511263 20080758 30527812 26221961 31806368 23545497 22908223 29125880 26385923 16153868 27348524
MAVS TANK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 19668221 19479062 17327220
NCOA3 SRC â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 19305643 12650696 17671194
TNIP2 NFKB1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 35140242 15169888 27609421 14743216 25609649 29084252 21988832
NFKB1 TNIP1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 19695220 35140242 14743216 25609649 21988832
SUMO1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18093978
BIRC3 TRAF2 â—¼   UBIQUITINATION ✅ - 0.9 0.9 Signor 18997794
TRAF6 IRAK1 â—¼   UBIQUITINATION ✅ + 0.9 0.9 Signor 18347055
TRAF2 RIPK1 â—¼   UP_REGULATES ✅ + 0.9 0.9 Signor 10795740
TRAF2 RIPK1 â—¼   UBIQUITINATION ✅ + 0.9 0.9 Signor 18621737
RPAP3 HS90B â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 17643375 24794838
TRAF6 UBC â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
BIRC2 TRAF2 â—¼   PHYSICAL_INTERACTION 919.0 0.91 STRING 36370105
TAB2 TRAF6 â—¼   PHYSICAL_INTERACTION 920.0 0.92 STRING 36370105
RIPK1 TRAF2 â—¼   PHYSICAL_INTERACTION 921.0 0.92 STRING 36370105
CBP IKKA â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 17434128 12789342 14597638 11971985
EGFR SRC â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
NFKB2 IKBB â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 28514442 26186194 14743216
CIKS TRAF6 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 19825828 25202827 12459498 16189514 17277779 22851696 30892082 31174059 21516116 32350852 25416956 21822258 20953186 23737552
IKBA NFKB2 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 33961781 32912968 26496610 14743216 26186194 28514442
TRAF2 TNAP3 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HIPPIE 8692885 30561431 24008839 32296183 16713569 25416956 10544141
IKBA IKBB â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 33961781 14743216 26186194 28514442 22081069
NFKB2 IKKA â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 15140882 16651533 16303288 21131783 14743216 17563756 17962807
AKT1 HS90A â—¼   PHYSICAL_INTERACTION 0.95 0.95 HIPPIE 10995457 31980649 12586360 21767636 15843522 22504172 25714412 16027165 12176997 29311840 19356729 16189514 32707033 29139175
IRAK1 TRAF6 â—¼   PHYSICAL_INTERACTION 959.0 0.95 STRING 36370105
NCOA3 CBP â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 21914189 9445475 17043108 9192892 11823864 33589584 16227615 8616895 9267036 15383283 26267537 11971985 11076796 16713569 9346901 21632823
NFKB1 IKBB â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 35140242 27609421 14743216 26186194 28514442
RIPK1 TNR1A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 24130170 31406107 19524513 30420664 21113135 25388546 7538908 22179575 29431638 19773432 15258597 19815541 23429285 22733818 27321185 8612133 18939944 22817896 16968706 11002422 16611992 20825417 18724939 25681446 27591049 24758719 20448643 26802121 28514442 21737329 8985253 18621737 28388439 21331078 22848449 16115877 19781631 24098568 27552911 18022363 18450452 18949366 28817177
TRAF2 TNR1A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 31406107 30420664 32968279 20333651 26212014 22179575 15743837 8943045 19815541 27321185 8612133 16713569 16611992 30561431 24735611 20448643 16189514 28388439 18776134 25241761 8565075 29108854 18022363 11821416
FADD TNR1A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 16611992 9129204 11035039 15659383 8565075
IKBA NEMO â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 26865630 32246052 19959994 26496610 15218148 17363973 21811235 15749833 15670770 21217772 22081069 18519641 23732909 14743216 18957422 16319058 11830587 21862596 16547522 21896478 11064457 23746843 18429822
IKKB KEAP1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 24322982 30126895 20600852 25926686 19818716 24127568 27387502 30500824
M3K7 CDC37 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 31980649 19026643 14743216 32707033
M3K7 HS90A â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 32707033 14743216 19026643
PP2AA AKT1 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 11839802 26256536 11438723 18191226 16044149 20005908 12637511 27563096 20186153
TRAF2 TNR3 â—¼   PHYSICAL_INTERACTION 0.96 0.96 HIPPIE 33961781 20348096 20732415 14517219 12169272 26186194 10799510 16713569 9162022 28514442
TANK TBK1 â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
BIRC2 UBC â—¼   PHYSICAL_INTERACTION 967.0 0.96 STRING 36370105
NEMO IKKA â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 24469399 19815509 10968790 19959994 26496610 9751060 11080499 16497931 30913450 11485410 12138192 20434986 10733566 22990857 17363973 25355947 17244613 18462684 16583354 17977820 23986494 20098747 11864612 15749833 24618592 32935379 17568778 12486103 23131831 26500060 32707033 32731169 21455180 22547678 28249776 30561431 11877453 18266467 14743216 16319058 12459277 17728323 23016877 30404796 17000764 15184390 27929056 25304104 28514442 21703539 11057907 10980203 16938294 16611882 21903422 19666608 20368414 12612076 22605335 18207244 12244103 18949366 18079694
IKKA IKKB â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 12210728 16286467 10968790 9751060 11080499 20434986 10733566 21784860 9346241 25748427 11864612 16713569 9346485 12486103 32707033 30500824 16129692 9346484 21575199 25852190 14743216 16319058 23016877 11971985 9721103 28514442 11057907 21903422 20932476 25241761 17693255 11585904 9914500 12244103
TAB2 M3K7 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 25642820 20538596 16845370 24061540 19026643 31127032 30348973 32303555 16603398 22081109 24270572 17384642 12242293 19955178 22158122 12609980 11259596 28507161 27426733 10882101 34535633 32707033 14633987 26432169 22167179 14743216 32410369 31250519 18021073 20200282 20194509 27468689 14670075 19232515 24912525 33717111 21903422 19556242 8638164 17158449
NFKB1 IKBA â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 35140242 7891711 20237821 26496610 8887676 8631829 27609421 32912968 11313474 33572115 20558726 9566883 20980497 16210649 14743216 22536447 9865693 9738011 21988832 11020244 28514442 29439025 9572494 25609649 26186194 7739549 17003112
CDC37 HS90A â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21871133 25036637 33961781 27353360 22729780 26496610 19875381 12930845 9685350 15647277 16335536 25486457 24462205 22504172 22939624 22315411 12176997 20159553 24292678 24189400 21360678 26804907 15001580 11413142 21745565 14718169 16611982
CDC37 HS90B â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 28215707 25036637 33961781 26496610 11036079 22939624 23428871 27339980 24189400 25486457
TRAF2 BIRC2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 16891304 33961781 23524849 20184394 24276241 21331077 11907583 8943045 19815541 9384571 23007157 8548810 20447407 16713569 16282325 30561431 32296183 25681446 25716317 19584093 21988832 8643514 19506082 28514442 30359437 15861135 16189514 20348096 21653699 20562859 21903422 25241761 10753917 11181075 16263936 27534557 25882049
TRAF2 BIRC3 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 16891304 33961781 15310755 23543740 23524849 21331077 11907583 19815541 9384571 23007157 8548810 30948266 16713569 16282325 20385093 21988832 24464131 8643514 20562859 25241761 10753917 27534557
SRC EGFR â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22227249 17284441 24658140 17158602 21278788 20333651 28065597 7527393 7797556 10777553 16713569 20624308 23175185 7506422 22973453 20935677 24189400 11983694 10075741 31980649 19704002 10358079 10971656 21268077 9020193 25402006 21573184 8845374
NFKB1 NFKB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 35140242 15660126 15169888 27609421 14743216 25609649 21988832 17962807
TBK1 TANK â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 31114588 30420664 23286385 18307994 23007157 21931555 17568778 32707033 30561431 10581243 29395067 14743216 21988832 17823124 25409927 24488098 16189514 29251827 27035970 21903422
TNIP2 UBC â—¼   PHYSICAL_INTERACTION 974.0 0.97 STRING 36370105
MAVS TRAF6 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
HS90A HS90B â—¼   PHYSICAL_INTERACTION 0.98 0.98 HIPPIE 31536960 25036637 33961781 26344197 26496610 20353823 19875381 22863883 21360678
RNF31 UBC â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
SENP2 SUMO1 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
TAB2 UBC â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
BIRC3 TRAF2 â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
FADD RIPK1 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
PRKDC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 318.0 1.0 Omnipath 27120806 14555685 20028775 20176926 11287317 27542271 26740621 11731414 12393602 34197700 17993646 21940452 21946537 11278872 22975685 16908595 18316359 34073781 24735537 18039660 24652283 20856200 26170313 21300025 15388791 19144640 26297026 17545609 33941854 16280327 10625301 33845796 25918246 34385295 17537996 14645219 20804212 15084259 12169689 21795477 22071574 23913047 34021259 21695150 15684384 33958720 14530366 16670089 19487463 19223464 17303569 25481872 15475446 17116771 28967905 33753495 12438236 29562639 16753042 33836561 19073147 15169778 16891474 19477925 16338973 16397245 34562454 15821749 33767437 34087103 11409731 18381446 15737995 27481935 11313365 26700621 17210635 25447541 33931486 17827393 17126298 15262962 28542588 33574930 11821945 20471940 15461589 17077177 33579227 26921343 17386266 33744230 26848618 12944390 33566837 26902421 21042280 21763421 34380642 18321849 14593122 25775124 25739674 17229808 26351843 24102046 23757022 33532186 16043647 24632620 12781924 25738875 10864894 17974989 25719244 15806160 16497987 25851605 20501647 18439899 28209968 10973320 24819169 25745998 34383763 19592491 19244117 19204084 29088759 26871475 34257082 26755732 17237292 17709744 17640984 34405859 18480058 33995548 22310280 20211239 12052823 22580611 31937616 19920202 26745759 15905173 12499277 15028555 27162341 21106850 33562475 30065170 23462102 15678105 15642728 27065332 28558072 28977846 15319269 21339742 15855334 21045808 20145118 21297104 18632646 17379600 15471950 23474758 26887938 11375271 20013032 18701889 16540596 15314172 28515473 15964826 19638206 25892239 28692056 20530876 27505672 25100728 21242970 17297446 10542266 14670178 15548374 33741342 12429574 11002428 15831486 17116756 25435370 32833881 11402048 25361894 15207915 20729916 15625077 18677106 12869565 11250155 21356307 15967841 31936857 25943101 18394555 12644590 14500543 18691549 27197158 15623569 33477794 12062056 16754797 15383526 21909137 21949775 20085797 16807298 15899889 33868961 23940660 23434580 33927349 23899556 14990993 12000752 27880719 26065416 19060924 34520759 14679308 15334055 17283158 25257795 17548608 30586628 24437487 20124472 15289327 23325788 21208159 33664452 31679687 12791703 15047712 17166829 26146988 17329400 20660158 21532621 21806543 20179209 25661488 20957047 17562705 19915805 12606948 17277771 10377409 25893295 17270736 16407838 20597130 15047168 28658616 16357520 15537647 12818176 11425855 17210830 19800394 12506011 21310961 16963136 21996732 15695828 33835469 11701613 19010331 26686089 28915558 15467762 17586693 18456663 34381564 18765673 20233713 34208786 11029403 22084251 20622007 12077256 11313948 16917505 19448664 27391337 15792956 21172654 15608670 12438239 19875458 22014578 25071014 11809760 18728186 31391321 33891611 19805619 33407730 25868858 25320242 34348155 20832730
TBK1 AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 21329883 21464307 21106850
SRC AKT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11445557 25241761 23242524 18283331 12600984
AKT1 IRAK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11976320
ATM PARP1 â—¼   ENZYMATIC_REACTION ✅ 54.0 1.0 ACSN 11331603 11438669 11804596 11877377 12086603 12556884 12607003 14988723 15136767 15140942 15175241 15459660 15485915 15798197 15867354 15964794 16163361 16332722 16581787 16713580 16731533 16805667 16858402 17102137 17116885 17296725 17303408 17384638 17582221 17713585 18006705 18048416 18469862 18511906 18583988 18716619 18756267 18995830 19151707 19282663 19342888 19357644 19490890 19622404 19788416 19793801 19793861 19841479 20019063 20051983 21376743 23847781 9168117 9858600
ATM TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20932475 21872579
ATM PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 17189255 12231622 17303408 24492479 10464290 22230547 15677476 16822724 28985363 29088817 16163361 32868446 19549901 25818648 22923485 19103741 17570479 27939942 19808981 23847781 22355272 24714417 15964794 21376743 31983282 25224041 16908529 12607003 19244120 17525332 15459660 34249431 28107384 12186630 25714019 11877377 26553138 27568553 19535303 15507430 26578593
BCL10 MALT1 â—¼   PHYSICAL_INTERACTION 22.0 1.0 ACSN 11280761 11356195 11460167 12356734 14660645 16809782 16818229 17052756 17301840 17363905 17462996 17948050 18264101 18264787 20685844 21133840 21199863 21232017 21873235 24560716 24699077 24958845
BCL10 MALT1 â—¼   SHARES_COMPLEX 22.0 1.0 ACSN 11280761 11356195 11460167 12356734 14660645 16809782 16818229 17052756 17301840 17363905 17462996 17948050 18264101 18264787 20685844 21133840 21199863 21232017 21873235 24560716 24699077 24958845
TRAF6 BCL10 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 11274345 12620219 14660645 15125833 16252010 17948050 18264787 18758450 18922473 19161412
RIPK2 BCL10 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 14638696 10825200 14695475
NFKB1 BIRC2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15050749 17673602 12687011 15756023 9733516 12010810 18566231 16453001 20103608
TRAF2 BIRC2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 54.0 1.0 Omnipath 21653699 25681446 8943045 8643514 11907583 16713569 20184394 18621737 18997794 21988832 25882049 9384571 21903422 16891304 10753917 20447407 18981220 16189514 15861135 11181075 20348096 20562859 25241761 19584093 32296183 21331077 23007157 16282325 19506082 25716317 23524849 24276241 16263936 12887920 8548810 19815541
BIRC2 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 12887920 18570872 20547836 15147886 21931591 16603398 19284370 18621737
BIRC2 RIPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19464198 16189514 21931591 9642260
NFKB1 BIRC3 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 21725609 23178297 23572150 9294162 9733516
NFKB1 BIRC3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 15231833 15050749 19343319 17673602 17000776 11880364 10733571 9733516 18566231 12010810 15723831 10823821 11297551
TRAF2 BIRC3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 18997792 8643514 11907583 16713569 18621737 18997794 21988832 18606850 9384571 16891304 10753917 18981220 24464131 20562859 25241761 23543740 20385093 21331077 23007157 16282325 23524849 8548810 19815541
BIRC3 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18570872 33526051 15147886 21931591 16603398 19284370 18621737
CYLD TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12917691 12917689 16230348 29933112 18382763
CYLD TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 12917691 23405219 17851586
NFKB1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 14678988 18367518 12469217 17881446
SRC EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 232.0 1.0 Omnipath 16414009 17081983 25958313 16943190 15618223 19935697 19305428 25402006 24797263 29285309 7488034 15592458 17389395 16461772 20562096 19275932 17897439 15899872 17570479 2803273 23636329 23246962 25505586 23175185 15615697 23349873 16849545 25356505 11983694 24189400 11756413 25748412 26325669 26150526 14512423 18789131 14750954 31978707 25573954 27495374 20071362 18707149 28759036 16729043 26494466 27716204 25537504 17237269 18687633 25884760 29036202 26936397 17575160 20926745 20935677 15282306 23702846 15476828 9069259 19336574 20421302 15660394 23866081 19377510 9777370 22426783 29321659 33706413 25841779 19840943 18669648 12397069 16843263 18957516 34088769 25077442 14963038 19836242 17653080 19625610 16936701 11960379 15548697 18295415 17523611 21268077 20333651 21399647 23376850 11250711 23942551 19704002 22927910 11160627 31952541 10777553 17016520 2543678 19258037 33883672 17646646 28102297 23873690 26771606 21573184 23119029 19151764 16713569 7797556 25955608 15302935 20407013 28513565 23119185 9990038 21080693 20190765 25347738 14630916 15708852 21822308 20628053 25301722 24658140 19690143 27564112 20802523 29124875 33657368 12101233 21787862 14764607 17284441 12878163 26290602 15951569 16543144 15212693 17971399 14523024 10971656 21278788 8845374 22430206 18083107 29641465 18234969 18460189 17551925 22957061 26571308 17043637 20371672 10358079 16799092 19154417 23066441 28065597 12842895 18180459 17158602 18271526 15657067 25159151 34367939 24919575 10075741 25366117 24349301 17561374 16862179 20215522 31980649 24335899 16037379 18451158 14530278 16505275 12063263 23449029 11311660
RIPK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11116146
EGFR PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 23956138 23178489 18237807 18789131
TRAF2 FADD â—¼   PHYSICAL_INTERACTION 74.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11875494 12215447 12646658 12702723 12724420 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21826665 22427918 22955274 23010170 23069999 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 8910423 9488730 9759866
RIPK1 FADD â—¼   PHYSICAL_INTERACTION 90.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11875494 12215447 12646658 12702723 12724420 12811837 1431106 14607933 14625680 14660645 14730360 14744430 15099563 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17916596 18264787 18545270 18633355 18641653 19392652 19411070 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21826665 22421439 22427918 22955274 23010170 23069999 23073834 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24366341 24378531 24699077 24958845 26024392 26201938 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 8910423 9184224 9217161 9488730 9759866
TRAF2 FADD â—¼   SHARES_COMPLEX 74.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11875494 12215447 12646658 12702723 12724420 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21826665 22427918 22955274 23010170 23069999 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 8910423 9488730 9759866
RIPK1 FADD â—¼   SHARES_COMPLEX 90.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11875494 12215447 12646658 12702723 12724420 12811837 1431106 14607933 14625680 14660645 14730360 14744430 15099563 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17916596 18264787 18545270 18633355 18641653 19392652 19411070 19427028 19498109 19524512 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21826665 22421439 22427918 22955274 23010170 23069999 23073834 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24366341 24378531 24699077 24958845 26024392 26201938 26587781 26653790 26853145 26900751 26972597 27558815 27984721 28498367 28574505 28645028 8910423 9184224 9217161 9488730 9759866
TRAF2 FADD â—¼   ENZYMATIC_REACTION ✅ 74.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11875494 12215447 12646658 12702723 12724420 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21826665 22427918 22955274 23010170 23069999 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 8910423 9488730 9759866
FADD TAB2 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
FADD RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 38.0 1.0 Omnipath 16585540 22864571 26733177 11002422 11854271 19524512 21458669 21525013 21052097 26865630 21741934 23972990 21620750 26186194 27560715 24098568 20203691 16227629 32296183 18485876 32024820 22890322 11464215 21737329 12887920 21183682 19524513 26972597 19373245 22848449 24577083
TRAF6 IRAK1 â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 11274345 12150927 12620219 12738796 14660645 15125833 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849
TRAF6 IRAK1 â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 11274345 12150927 12620219 12738796 14660645 15125833 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849
TRAF6 IRAK1 â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 11274345 12150927 12620219 12738796 14660645 15125833 16252010 16878026 17704786 17948050 18264787 18758450 18855897 18922473 18977329 19161412 21614932 23070005 23681101 23811849
IRAK1 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 66.0 1.0 Omnipath 10346818 17145710 17785851 16024789 14625308 11259596 10383454 18234474 9374458 11287640 23244239 21220427 11518704 19166926 16951367 15894263 10747026 35926385 18056395 12566447 12496252 22447928 12242293 8837778 10920205 11960013 19716405 24735611 20043910 24434549 17785432 11397809 18347055 22033459 12140561 23381138 17197697
IRAK1 TAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 11518704 12242293 19675569 23331499 18180283 21071413 11259596
TRAF6 MALT1 â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 11274345 12620219 14660645 15125833 16252010 17948050 18264787 18758450 18922473 19161412
TRAF6 MALT1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 15125833 17948050 22528498
MAVS TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 21813773 15210743 16127453 33372174 17020950 25636800 21903422 15210742 16753195 16306936 12702806 24643253 16177806 27419230 16153868 16858409 29743353 17468758 17327220
NFKB1 TRAF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15723831 15041463 19392652 18990758
TNIP2 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 21988832 25609649 14743216 15169888
TNIP1 NFKB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 21988832 25609649 14743216 19695220
TRAF2 RIPK1 â—¼   PHYSICAL_INTERACTION 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
TRAF2 RIPK1 â—¼   SHARES_COMPLEX 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
TRAF2 RIPK1 â—¼   ENZYMATIC_REACTION ✅ 92.0 1.0 ACSN 10465784 10734135 10925299 11003656 11112697 11274345 11280761 1134007 11438547 11460167 11583996 11668179 11875494 12048245 12215447 12556535 12646658 12655147 12702723 12724420 12738796 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15170913 15310755 15592525 15699106 15760909 16406523 16498403 16713974 16940415 17301840 17462996 17496911 17916596 18264787 18292600 18633355 18641653 18855897 19392652 19411070 19524513 19597341 19632174 19838173 20038811 20184663 20435894 20452955 20531300 21133840 21232017 21411734 21614932 21826665 22427918 22955274 23010170 23069999 23070005 23170255 23377657 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 27984721 28574505 28765050 8910423 8974401 9379049 9488730 9582321 9759866
RIPK1 TAB2 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TRAF2 RIPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 8702708 8612133 25416956 16713569 18621737 25882049 16291755 18981220 21741934 21232017 20577214 11181075 10795740 23972990 21119000 15175328 20203691 21810480 21282461 9712898 32296183 23007157 25716317 20448643 12887920 24735611 15258597 24434549 19815541 16603398 11479302 9020361
RIPK1 TAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15327770 16603398
TRAF2 RIPK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16713569 9705938 21903422
SUMO1 SENP2 â—¼   CLEAVAGE ✅ 7.0 1.0 Reactome 16253240 15487983 16738331 12192048 11896061 17591783 14563852
TRAF6 TAB2 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12150927 12620219 14660645 15125833 16252010 17948050 18264787 18758450 18922473 19161412
TRAF2 TAB2 â—¼   ENZYMATIC_REACTION ✅ 57.0 1.0 ACSN 10925299 11003656 11112697 11274345 11280761 11438547 11460167 11875494 12646658 12811837 1431106 14607933 14625680 14660645 14730360 15099563 15592525 15699106 16713974 17301840 17462996 17916596 18264787 18633355 18641653 19392652 19411070 19524513 19632174 20038811 20184663 20435894 20531300 21133840 21232017 21411734 21826665 22955274 23010170 23170255 23430059 23508573 23510023 23567181 23769623 23850759 24092389 24378531 24699077 24958845 26201938 26587781 26653790 26972597 28574505 8910423 9488730
TRAF6 TAB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 17145710 15492226 19675569 15932500 18180283 16251197 10882101 18299187 11259596 1551980 24061540 21988832 19112497 22924441 11518704 11809792 15836773 14633987 14751757 25290089 12496252 12609980 12242293 24735611 14982987 15327770 17720800
TANK TBK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 35.0 1.0 Omnipath 16127453 17568778 27035970 25409927 23286385 18307994 24488098 21419663 21988832 21903422 15210742 14743216 16189514 19820708 21931555 10581243 23007157 17823124 17468758 17327220
TANK TRAF2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 20562859 21988832 21903422 8710854 12005438 14743216 10581243 16713569 23007157 10759890
PRKDC ATM â—¼   KO_DOWN_REGULATES ✅ - -1.5 1.49 PKG 28854368
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368