Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
MDM2 MDM4 â—¼   COLOCALIZATION 2.0 0.8 intact 17159902 5219425
IKKA P53 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 17434128 32707033 16713569 11805286
LMBL1 P73 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CF141 P73 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
SKP2 P73 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
NFYC P73 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15454570 12167641
MYC TDG â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21150319 26496610
IER2 P73 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
EP300 P63 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 25911675 15965232 30986748 23589370
NFYB EP300 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 9799238 15454570 10075648
KAT2B MDM2 â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
TDG P53 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 18951877 10961991
P53 NFYB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 16959611 15831478 23734815
P73 NFYB â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 15454570 12167641
TDG P73 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 18951877 10961991
P63 DAXX â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 12954772 15339933
P73 KAT2B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 14614455 18663001
DAXX P73 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 12954772 15339933
MDM4 P73 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 33961781 11223036 21088494 29523541 30603043 28514442
P73 P53 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 25417702 11238924 9891077 21508668 9802988
P53 ABL1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 10713716 16713569 10629029
P53 ITCH â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 18559494 16908849 32807901 21474069
IKKA MYC â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33461590 21575199
MYC EP300 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12776737 16287840 32140074 15616592 16126174 17157259
MYC SKP2 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
EP300 MDM2 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
WWOX P73 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 15070730 24550385
IKKA P73 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17452332 21482671
P63 YAP1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 27780825 11278685
SKP2 EP300 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 18243116 22770219 26593157
DAXX MDM2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
EP300 KAT2B â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
MYC P53 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 21150319 30415952 28205554 28628118
P73 MYC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12080043 11844794
P63 P73 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 11238924 22252508 17446929 28514442 10373484 19815500
MDM2 DAXX â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 6799761 18566590
KAT2B EP300 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 12888487 22384255 9267036 12419806 21413932 20870727 33051058 8684459
NFYC MYC â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 10446203 11282029
WWOX P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 16219768 31315632 14965474 12514174 15580310 16713569 11058590
KAT2B P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20589832 17189186 16537920 14614455 12501250 10891493 17977830 9744860 19680552 10490106 15965232 9891054 16959611 16678111 12068014
EP300 P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 29706626 25156994 12724314 23728348 16543236 12501250 9652736 9194564 18243116 9194565 19339993 16678111 16611888 11359905 11782467 12162806 14612423 14759370 15186775 15664194 9288740 23402884 17452980 24157709 9891054 12499368 19234109 27818144 16537920 17977830 15295102 10518217 16713569 26625199 16928824 11070080 17906639 23870121 23796514 15558054 17438265 25867071 17189186 18485870 11907332 15542844 19217391 32807901 16438982 31167125 15337767 10490106 22731250 12690203 25288747 18612383 23329847 24821727 26302407 9809062 16959611 22074660 19218448 16782091 23880760 33196849 25753752 28757384 18391200 16024799 25651062 16135789 22013068 11433299 9744860 10601022 21187340 11804596 23307557 10942770 15509808 20234175 21471221 26229107 19805293 22266186 15965232 23010591
MDM4 P53 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 31462704 10827196 19255450 22745160 23671280 31066983 10075736 10629057 11528400 15604276 24445145 19521340 19075013 12370303 30598450 21965653 19432880 16024788 31152661 21088494 22807444 17301054 30832340 17875722 16713569 20724842 28628118 16227609 30672125 25464845 25825738 22266850 24659749 20515689 21075307 20174603 18316739 17110929 20705607 10608892 24127580 29023092 26876197 24667498 9226370 18677113 27114532 28514442 22374672 17080083 8895579 12393902 29523541 32511789 30045945 19305137 23028042 18485870 11223036 26148237 25609649 19153082 26186194 21925390 28205554 23946421 28487147 15916963 12874296 25961923 27249653
P73 MDM2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20588255 25417702 11223036 10435614 10207051 21261729 19218448 30603043 10321734 21088494 26025930 18499675 25301064 10469568
EP300 P73 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 15175157 15454570 25675294 19218448 18663001 10648616 11804596 15893728
P73 ITCH â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 32513985 30603043 15678106 17592138 17110958
ABL1 P73 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 25893286 10391251 10391250 11278685 19442657
YAP1 P73 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 31496812 18280240 18640976 25283809 11278685 27292796 19111660 15893728 17110958
ITCH P63 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20855944 23370280 22935697 25485500 16908849 33619536
ABL1 MDM2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 12110584 25624478 16702947
MYC ABL1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21400515 23029531 19602047
MDM2 EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9809062 11070080 16713569
MYC KAT2B â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 35140242 12660246 15572685
MDM4 MDM2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 26720344 33961781 27621617 26359458 10827196 10629057 24755078 23671280 22902369 22745160 22333590 15604276 20484049 18566590 12370303 30598450 31796886 10218570 19432880 34551723 12483531 29524278 17159902 27777309 12860999 27215386 11606419 18219319 17301054 19683495 25512388 20724842 28628118 16227609 22493164 20473904 25384516 26001071 25825738 22266850 29057323 25809483 25703327 32427989 20705607 10608892 31024344 19619542 21988832 29262653 25659040 29523541 28514442 27617579 29295817 33985974 12393902 16055726 23028042 24813712 22120712 32300648 32075226 21925390 17616658 28205554 23946421 19838211 25105592 12874296 25961923
P63 P53 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HIPPIE 25417702 11238924 24554706 22575646 23687300 16713569 19345189 21741598
MDM4 MDM2 â—¼   COLOCALIZATION ✅ 0.93 0.93 mint 17159902 5219425
P53 MDM2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 21317885 11839577 23201157 21316347 25312347 22975381 17369817 21084285 30005830 23443559 21465263 10980696 17936559 10488081 16845383 21149449 22366412 23483203 29549180 14741215 26673821 11713288 18665269 15058298 29524278 28514442 22510990 25241761 22525275 19106616 22467867 25954860 10889512 16595680 24998844 15848166 28628118 28362432 17116689 33650658 14499615 24980433 10608892 26876197 17438265 22103682 22374672 16055726 7689721 17363365 19411066 12167711 23318437 18566590 31796886 30244831 12944468 23261415 27215386 27826076 11178989 19223463 17301054 9724739 32894144 21075307 29121928 19305137 17318220 20659896 20080206 7686617 11744695 18467333 23246961 23150668 23776465 16215989 9223638 16331255 31968249 17908790 14702041 15094782 11278372 28605833 31647545 24200963 10601022 21454483 27893708 21088494 32516735 16861890 26238070 20705607 21887275 19303885 25609649 12915590 31406141 27282385 25156994 23671280 15358376 23609977 25168242 19071110 22991965 22653443 22920093 7926727 17470788 26908445 27856536 26475964 19857530 11709713 11714701 30532073 19411846 11094089 20173098 17591690 9582019 12552135 20542919 28205554 14704432 15001357 29876924 25417702 23880345 20124408 19033382 22487680 30598450 33061576 22575647 9131587 17159902 31152661 17297477 9271120 25384516 24659749 21261729 12529318 22411991 14671306 22084066 20395212 21986495 29487367 33355139 23802716 23370271 23946421 22083959 32807901 15154850 29670376 27905468 35140242 25283148 22085928 11562347 10640350 19098711 32901886 21726810 25624478 25637791 21584881 16870621 12690203 12612087 15824742 11572869 25464845 26203195 22157679 30454706 28082682 9809062 17302414 19085961 24567357 25362358 17080083 17426254 15242646 22524527 29295817 16751805 11431470 26882543 30097011 18604177 20591651 22948151 24462112 10827196 20479273 31533005 22389628 21170087 20694676 17666403 11597128 33503543 14596917 18332869 10321734 21857681 16579792 16414131 18264029 21071676 30464405 17989425 20234175 10681559 27308622 19816404 30355102 19805293 9824166 25313037 16173922 24926618 16159876 26540344 18541670 32904724 17616658 12842086 26720344 27129163 22266868 27031960 32528731 22737255 15604276 16432196 19188367 1614537 22914926 24842904 15247280 32097779 23252402 17347673 16964247 17310983 22331460 30584071 22032989 24240685 31652301 10435614 24621507 24361594 15308643 32334023 16547496 20639885 17139261 15933712 21478269 15313915 23402884 21750659 11112690 19255450 22124327 25277184 19234109 21965653 27336364 15122315 22916255 22262183 15295102 31092600 25512388 16713569 26001071 27807478 31940492 20588255 20174603 20570896 20708156 27886165 17056014 19081178 29547122 23572512 16905769 15542844 19941302 10561590 28542145 32066565 16212962 10202144 28549433 10734067 21572037 18172499 9363941 15550400 17380154 10892746 14559824 22227409 18316739 33495326 17234751 15280377 31177307 24127580 19160491 17290220 8875929 12381304 16857591 18813780 10347217 21561866 24413661 31066983 20847049 21098709 25103245 8058315 22807444 30832340 21268072 20962272 26350565 30175854 20591429 22444248 32427887 16023600 24667498 11351297 11285227 11223036 18784078 11384992 10562557 19568783 31138778 21925390 11486026 19597489 9450543 31665549 22318540 27106262 24207125 15950904 18223694 23728348 22474335 34362424 22912717 20047188 14612427 14517261 30679555 18815136 18061646 28394340 34408321 18309296 11046142 15144954 12897156 23776060 15210108 27811966 19357310 22391559 16338390 29899406 34040386 26186194 11284721 15908921 23652204 33765973 31626714 17848574 9529249 25739118 30879903 10766163 15013777 22588298 18981217 29755129 30320499 11070080 22301280 27543608 30948704 19590512 15558054 12867035 24488098 27462439 18485870 17268548 22819825 31591476 23826318 21471462 9278461 16866370 22659184 19166840 20660730 29269425 31239268 32198344 25543083 17875722 10196247 15053879 21084564 16107876 16678796 17098746 19656744 30109812 11925449 17525743 16624812 30455251 19153082 28553961 21132010 26578655 32874188 31903119 29997244 19837670 20837658 26883110 21060154 33961781 33579943 20235143 15064742 26556313 22745160 20657550 20484049 16152627 11697899 18234963 24314634 12208736 30320919 11713287 28223335 30252118 10722742 31594538 19483087 22266850 24643130 20959462 33020477 21988832 12426395 19332559 23169665 12620407 23134341 27249653
NFYC NFYB â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 33961781 35140242 32296183 26344197 26496610 12401788 20936779 21988832 28514442 9388234
DAXX P53 â—¼   PHYSICAL_INTERACTION 0.99 0.99 HIPPIE 21134643 12482984 15339933 21482821 25241761 16845383 27626385 12954772 15364927 23038753 16713569 28875283 32545337 14557665
MDM2 MDM4 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
NFYB NFYC â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
ABL1 YAP1 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10837221 11804596 11971963 12628935 12709442 15459660 18835194 19788416 21051857 21199784 21435002 9168117
ABL1 MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 23331499 12110584 20651945 29065514 22352870 16702947 25973395 27626309 21081495 27956626 20841568 14757045 19738896 15212693 28690977
ABL1 YAP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 25361080 19788416 21199784 29449692 18955976 21051857 18280240 21435002 18701449 27807512 20841568 21214929 21945154 29179447 15459660
ABL1 MDM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 20651945 29262653 26148237 19075013 20841568 28690977 29348869
DAXX MDM2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 17145710 21134643 16845383 15364927 18566590 23405218 18583933 20195357 23038753
KAT2B EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8684459 14500836 9267036 17496784 20870727
EP300 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 17145710 22290435 19623618 11804596 23343194 22761862 16039586 12776737 17157259 17143292 12660246 15576399 21151179 15522869 17306568 19407812 17666529 21285352 19619488
EP300 TDG â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11864601
ITCH YAP1 â—¼   ENZYMATIC_REACTION ✅ 8.0 1.0 ACSN 10940313 11318614 16469705 16861923 18552861 18628966 21107885 21383157
MYC MDM2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 15655352 12695333 19649205 10348347
MDM2 MDM4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 69.0 1.0 Omnipath 17145710 10218570 17616658 16511560 22266850 12874296 21925390 25825738 21988832 25512388 16227609 22493164 22902369 25659040 18219319 12963717 15604276 18566590 12370303 19838211 26359458 27617579 25809483 34551723 10608892 23028042 22120712 25703327 12860999 32300648 16055726 24813712 17301054 12483531 23671280 17159902 27621617 25105592 20484049 20724842 27215386 10827196 26001071 11606419 23946421 19683495 20705607 24755078 25384516 20473904 12393902
MYC SKP2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 24259667 12963825 12769844 23792459 21245140 24177224 23277542
SKP2 MYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17145710 24259667 12963825 12769844 17157259 23277542 20852628 16376880 35260179 26038816
MYC NFYC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11282029 10446203
TDG TDG â—¼   KO_DOWN_REGULATES ✅ - -3.98 3.97 PKG 28854368