Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GRB2 DHX9 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
FYN GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
LYN GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9209406 8400282
LCK GRB2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9694876 7737275
GRB2 MATR3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 ITK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10636929
LYN PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15644415 8034732
LCK FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 8946678 9973466
FYN LCK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17570479 22043010
RASA1 PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6805619 9020117
GRAP2 PLCG1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11390650 11048639
PLCG1 INSR â—¼   PHYSICAL_INTERACTION ✅ 0.8 0.8 mint 200301131 14568990 6804839
PLCG1 INSR â—¼   COLOCALIZATION ✅ 0.8 0.8 mint 200301131 14568990 6804839
RASA1 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 9020117 9743338
SRC FYN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219079 16966330
FYN NCK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219079 16966330
RASA1 INSR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6805769 9593725
CRK GRB2 â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
CBP SRC â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 16860316 15615775 16713569 22364282
EP300 KHDR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30110629 21988832
LYN YES â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 33961781
MATR3 EWS â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29884807 26496610
MATR3 RBMX â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29511296 26496610
MATR3 RU17 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29802200 26344197
KHDR2 PLCG1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
HNRPK PLCG1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
BMI1 KHDR3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
BMI1 KHDR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24457600 34316702
HNRPQ U2AF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 26641092
HNRPR U2AF2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22939629 26641092
U2AF2 KHDR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22365833 26641092
U2AF2 ROA1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34079125 26641092
KHDR1 RBMX â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31413325 21988832
RBMX HNRPR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34133714 22939629
RBMX RU17 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 29802200
HNRPQ HNRPK â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 22365833 22939629
HNRPK RU17 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29802200 22939629
EWS KHDR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29884807 24999758
FBLN3 KHDR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31413325 21988832
RU17 KHDR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 29802200 31413325
PACN3 KHDR1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19041431 26344197
KHDR1 HNRPQ â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31413325 26344197
KHDR1 ASPP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 16474851 22745667
KHDR3 HNRPR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 34133714 26344197
MATR3 DHX9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29884807 26496610
MATR3 HNRPR â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29884807 26496610
MATR3 KHDR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29511296 29884807 26496610
RU17 U2AF2 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 29802200 22939629 26641092
RBMX YTDC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
KHDR1 BTK â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 22745667 9201297
BTK EWS â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 16713569 9201297
KHDR1 SH3K1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31413325 22745667 19531213
HNRPR KHDR1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 31413325 22939629 26344197
ROA1 EWS â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 34079125 29884807 25324306 22446626
RU17 YTDC1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 29802200 33961781
RASA1 GRB2 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16189514 12441060 16713569
HNRPK LYN â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 7516469 23503679
LYN HCK â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 31980649
LCK STAT3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16189514 25814554 10825200 18070987
CRK SRC â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 23397142 10962563 12615911
LCK YES â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 32707033 31980649
INSR KHDR1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 10437794 11604231
WBP4 HNRPK â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16055720 28838205
KHDR2 ANM1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 17643375 12529443
WBP4 EWS â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 16055720 24999758
SRC GRB2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 16189514 16713569 11964172 9016807 12624098
SRC LYN â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 9169421 18070987 22581261
KHDR1 CRK â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 7537265 11278465 1545818
CRK NCK1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 8879209 9837978
SRC PLCG1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 1689310 7510703 16713569 7682059 8657103 8885868
PLCG1 RASA1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 9020117 8977179 9743338
KHDR1 NCF1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 22745667 8766817
BTK HCK â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32707033 8058772
RBMX KHDR2 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 32296183 16189514 25416956 17643375 34133714 27107012
FNBP4 KHDR1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 10748127 11604498
INSR PLCG1 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
EP300 STAT3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10205054 15653507 16713569 33531691 26504087 18782771 30110629 11923478 15735682 15649887 33742100 22116549
ITK GRB2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 10636929 8985255
CBP STAT3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15653507 15649887 11239394
KHDR1 STAT3 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11585385 16713569
SH3K1 CRK â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 11071869 31980649
FNBP4 FYN â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 16713569 16189514 10744724
INSR RASA1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 1331107 9593725
GRAP2 KHDR1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9872323 10820259
KHDR1 DISC1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31413325 29961565
KHDR1 ITSN2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 31413325 22745667
KHDR2 HNRPQ â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17643375 26344197
SRC EP300 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 26695438 10973497
LYN BTK â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 11226282 8058772 11598012 8629002 8630736
HNRPK MATR3 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 29511296 32296183 16189514 25416956 16713569 26496610 29884807
ITK FYN â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 10636929 16713569 8810341
YES FYN â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 12640114 33961781
U2AF2 HNRPK â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 22365833 26641092 22939629
HNRPK RBMX â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32296183 16189514 25416956 22365833 21516116 22939629
HNRPK KHDR2 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 32296183 16189514 16713569 30886144 17643375
KHDR3 KHDR1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 16474851 22365833 10749975 33961781 31413325
EWS ANM1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 18320585 23455924
HNRPQ RU17 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 29802200 22939629 33961781
EP300 STAT3 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
CRK SRC â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
EP300 EWS â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 18509338 24999758 33742100 21988832
EP300 CBP â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 9267036 25314079 10899165 31753913 30110629 15598887 17970752
ROA1 MATR3 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 29511296 22446626 25324306 26496610 29884807 34079125
CRK P85A â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 25241761 11418612 10962563 12878163 25814554 19380743
HCK RASA1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16189514 7782336
SRC RASA1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 1717825 11389730 16189514 16713569
IRS1 KHDR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22005517 11604231 8175658
ROA1 RBMX â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 34079125 22446626 17643375 26496610
WBP4 KHDR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16055720 10748127 11604498
YTDC1 KHDR1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 10564280 31413325
SRC STAT3 â—¼   PHYSICAL_INTERACTION 883.0 0.88 STRING 36370105
ROA1 DHX9 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22446626 25324306 26496610 22863883 34079125
DHX9 ANM1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16713569 11850402 15084609
DHX9 KHDR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 22365833 10951562
KHDR1 LYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 7516469 22745667 9045636 15190072
MATR3 DISC1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 90000000 31413325 17043677 29961565
KHDR1 LCK â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 16888650 16274251 7852312 11278465 9045636 16107303
LCK P85A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 8294442 9461588 7504174 34079125 8246987
ITK PLCG1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12163161 10586033
SRC FYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31980649 19711372 9169421 33961781 16966330
P85A FYN â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 25416956 16713569 8294442 7520528 8394019
SRC P85A â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12210743 25241761 16713569 23065768 12393736 24498420 7499252 10487518 32814053 16230374 23397142 19861161 19903481
KHDR1 ITK â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 12163161 22745667 8810341 8985255
KHDR1 PTK6 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 31980649 10913193
KHDR2 KHDR1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 31413325 33961781 17643375
KHDR1 ROA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20186123 17371836 24514149 26496610 34079125
ANM1 ROA1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17264152 8663146 9891755 25324306 17643375 8288564 19101556
HNRPQ HNRPR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 29395067 22939629
KHDR2 HNRPR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 34133714 25416956 17643375 26344197
KHDR3 KHDR2 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 28514442 32296183 16189514 17643375 34133714 33961781
FYN GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7499280 9344857
RASA1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12441060 16713569
STAT3 PTK6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12540842 20929863 19393627
SRC STAT3 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16189514 21573184 15313931 11294897 8657134 18070987 10918587 12244095 19372587 12626508 8626374 14551213 16713569 8272872 11350938 9566874 12576423 11940572 15735682
LCK PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7682059 17570479 1500851
KHDR1 PLCG1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 10467411 9743338 11960376 7537265 8977179 9045636 14647465 31413325 7799925
SRC PLCG1 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 Reactome 15879121 20807769 11600407
INSR PLCG1 â—¼   COLOCALIZATION 3.0 0.9 intact 200301131 14568990 6804839
NCK1 RASA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 21664272 10508618 16189514 9233798
KHDR1 RASA1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 8189062 11604231 16713569 7537265 9743338 8419471 1385407 1545818
INSR RASA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1331107 9593725
KHDR1 HCK â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12029088 22745667 11278465 17141806
KHDR1 HNRPK â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 21988832 22365833 12370808 31413325
ROA1 HNRPK â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22446626 25324306 17643375 26496610 34079125 22939629
SH3K1 P85A â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 15476827 17474147 11071869 10921882 20457601
CBP EWS â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 12459554 32238831 24999758 16713569
ANM1 HNRPQ â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 32296183 12183049 23455924 29395067
KHDR3 ANM1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16713569 12529443
ROA1 HNRPQ â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 22446626 17643375 26496610 34079125 22939629
ROA1 HNRPR â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 22446626 25324306 17643375 26496610 26186194 34079125 22939629
GRB2 IRS1 â—¼   PHYSICAL_INTERACTION 912.0 0.91 STRING 36370105
INSR IRS1 â—¼   PHOSPHORYLATION ✅ + 0.91 0.91 Signor 7651388
HNRPK ITK â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 16713569 8810341
HNRPR ANM1 â—¼   PROTEIN_INTERACTION 0.92 0.92 HIPPIE 12183049 16713569 16169070 25416956
INSR IRS1 â—¼   PHYSICAL_INTERACTION 923.0 0.92 STRING 36370105
GRB2 BTK â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 19380743 20936779
HNRPK FYN â—¼   PROTEIN_INTERACTION 0.93 0.93 HIPPIE 16189514 16713569 7516469 9185665 31413325
INSR PLCG1 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 14568990 9593725 11796522 22974441
HNRPR RU17 â—¼   PROTEIN_INTERACTION 0.94 0.94 HIPPIE 28514442 29802200 22939629
KHDR1 APC â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 22000517 31413325
GRB2 HNRPK â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 25416956 31980649 12577067 21988832 19380743 20936779
ANM1 KHDR1 â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 17891136 17264152 16713569 19596784 10748127 12529443
KHDR1 YES â—¼   PROTEIN_INTERACTION 0.95 0.95 HIPPIE 31413325 22745667 15190072
PLCG1 GRB2 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 16713569 7629168 7516467 9020117 21706016 10940929 16038803 9281317
GRB2 SH3K1 â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 11152963 16189514 31980649 16713569 10921882
INSR P85A â—¼   PROTEIN_INTERACTION 0.96 0.96 HIPPIE 11796522 8276809 8385099 1334490 10500481 8567177 14729945 9593725 7589433 15629149 7659087
FYN SRC â—¼   PHYSICAL_INTERACTION 966.0 0.96 STRING 36370105
KHDR1 GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16713569 10467411 7537265 11960376 21988832 11278465 21706016 22745667 8576157 9045636 20936779 9872323 12112020 7799925
IRS1 GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 7488107 8388384 7486683 8810325 22974441 21706016 8491186 7629070 12173038 8536716
P85A GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 25416956 9174058 11418612 21706016 7544353 18346204 7737969 9886492 16219545 19380743 7642581 7759531 16713569 8621719 7642542 9541596 8647120 32814053 20936779
CRK GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 8810325 10962563 8662907 19380743 10970810
KHDR1 FYN â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16888650 31980649 16713569 11960376 7516469 15190072 22745667 9045636 14647465 31413325
KHDR1 NCK1 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 10805734 9362449 9010224 22745667 31413325
SRC HNRPK â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 16189514 17178840 16713569 7516469 16854432 12052863
ANM1 HNRPK â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19101556 12183049 16713569 12529443
KHDR1 P85A â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 11604231 16713569 10467411 7537265 22745667 10437794 8175658
KHDR1 CBP â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 17891136 16713569 32238831 28648376 12496368 15021911
KHDR1 SRC â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 10635328 16713569 7537265 10467411 11960376 1374686 15190072 22745667 16169070 8766817 18606683 1545818 9038356
INSR IRS1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 11781100 25667086 16582879 17167487 7935368 10455177 11606564 7499194 15629149 8662806 8626379
P85A IRS1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 29526746 16150444 14632132 22974441 8628286 26839216 8382612 7680095 33991522 25814554 16880210 19561084 16230374 8175658 7659087 8388384 1381348 23643389 23439647 7935461 12107746 11403293 15514089 7680644 12173038 25273559 14511371 12730242 11416002 7486683 17640984 1334490 30240640 16354680 12220227 9564850 16043515
EP300 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 25.0 1.0 Omnipath 18782771 15509516 8756628 10205054 7530500 15653507 15735682 19506034 16285960 16713569 11322950 7499365 15649887 9590694
IRS1 GRB2 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 8316835 8810325 9832424 8621421 8530377 9852124 9003010
GRB2 CRK â—¼   PHYSICAL_INTERACTION 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
GRB2 PLCG1 â—¼   PHYSICAL_INTERACTION 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 NCK1 â—¼   PHYSICAL_INTERACTION 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GRB2 PLCG1 â—¼   SHARES_COMPLEX 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 NCK1 â—¼   SHARES_COMPLEX 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
GRB2 CRK â—¼   SHARES_COMPLEX 32.0 1.0 ACSN 10086337 10567412 10811803 10849428 10982827 11335727 11447289 11449354 11532940 11777939 12175651 12393695 12640133 15308668 15567848 15574420 16000375 16076871 16530705 16582911 16887996 17496910 17673906 18835194 19449109 19454690 22064427 22464172 24217602 25922287 26552706 8551221
FYN GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
ITK GRB2 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11406363 12186560 15661896 25137453
LCK GRB2 â—¼   ENZYMATIC_REACTION ✅ 16.0 1.0 ACSN 10652356 11062502 12731048 12740575 15536084 17544292 19290918 20814939 21127503 22513334 23620508 8478617 8986721 9438848 9738502 9751747
IRS1 GRB2 â—¼   ENZYMATIC_REACTION ✅ 12.0 1.0 ACSN 10086337 10826997 12175651 12444011 12767520 16931767 17604717 19030972 21540285 22465479 24036369 8621421
GRB2 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 51.0 1.0 ACSN 10072481 10086337 10209041 10567412 10781611 10811803 10925299 10982827 11169415 11447289 11532940 11777939 11994416 12175651 12640133 1281218 12845332 14764585 15214048 15567848 15574420 16102570 16329184 16582911 16887996 1712101 17397400 17496910 17673906 19449109 19494291 19909365 23523669 23620508 24584707 25137453 2536067 25456276 25960930 26552706 7523143 7682895 7890616 8226994 8551221 8649391 8976179 8995379 9489702 9535722 9846483
GRB2 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
BTK GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20936779 19380743
IRS1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 8265614 7862167 11788580 8388384 8491186 8536716 7488107 7486683 10358772 10592173 8196603 12173038 12679424 8114695 11259577 8810325
SRC GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12624098 11964172 9016807 16713569 26103942 20554525
GRB2 PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9281317 15953601 7629168 9020117 16713569 10940929
LYN PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 45.0 1.0 Omnipath 17389395 12601080 8395016 16038803 10586033 1689310 20068231 1708307 7682059 8885868 15144186 16497976 8657103 15592455 16126727 17016520 16153436
LYN BTK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 18083107 8629002 12573241 11598012 19369195 10051622 9012831 8630736 9730885 10811866 9052864 8058772 11226282
SRC STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 88.0 1.0 Omnipath 19901323 10918587 9305919 8272872 29036202 9344858 12626508 10815799 16497976 15592455 16713569 17389395 12576423 11350938 9484840 11294897 28978186 18070987 12244095 27472461 21690253 23928694 22303479 8657134 11404481 9083098 14963038 8626374 17016520 9566874 10982829 15212693 11940572 11429593 14551213 15037656 15313931 11850821 9154828 9582023
LCK STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 11404481 9484840 9344858 18070987 10815799 16189514 10825200 25814554
HCK STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 58.0 1.0 Omnipath 19901323 10918587 9305919 8272872 9344858 12626508 10815799 16497976 15592455 17389395 12576423 11350938 9484840 11294897 12244095 11404481 9083098 8626374 9566874 11940572 11429593 14551213 11850821 17016520 9582023
PTK6 STAT3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18083107 17389395 21741923 19534553 7701321 19304789 16568091 15592455 12763138 15951569 20929863 18234692
IRS1 CRK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9837978 8810325 8621590
LCK FYN â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9822663 15886116 10849438 12670394
LCK ITK â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 10652356 12731048 12740575 17544292 19290918 20814939 21127503 22513334 23620508 3263576 8478617 8986721 9438848 9738502 9751747
LCK ITK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 29.0 1.0 Omnipath 21747996 28516764 19132916 23109003 20305788 23982207 15771581 19690332 28644030 15144186 9312162 12842872 17192257 23946894
LCK RASA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 11389730 1850098
PLCG1 SRC â—¼   PHYSICAL_INTERACTION 36.0 1.0 ACSN 10072481 10781611 10811803 10925299 11169415 11476890 11532940 11994416 12040186 1281218 12845332 14585353 14764585 15214048 16488589 16919435 1712101 17397400 17496910 17517963 19568798 19909365 23523669 24584707 2536067 25456276 25572304 25960930 26552706 27216177 7682895 7890616 8226994 8649391 9535722 9846483
PLCG1 SRC â—¼   SHARES_COMPLEX 36.0 1.0 ACSN 10072481 10781611 10811803 10925299 11169415 11476890 11532940 11994416 12040186 1281218 12845332 14585353 14764585 15214048 16488589 16919435 1712101 17397400 17496910 17517963 19568798 19909365 23523669 24584707 2536067 25456276 25572304 25960930 26552706 27216177 7682895 7890616 8226994 8649391 9535722 9846483
ITK PLCG1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 11406363 12186560 15661896 25137453
NCK1 PLCG1 â—¼   ENZYMATIC_REACTION ✅ 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
SRC PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 8388373 16497976 16126727 16713569 17389395 1689310 20068231 17570479 16153436 16038803 1708307 7682059 7510703 18594017 12601080 8885868 8657103 17016520
BTK PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9550384 15010370 15184383
FYN PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8395016 10586033 7682059 16713569
HCK PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 17081983 16497976 15592455 16126727 17389395 1689310 20068231 16153436 16038803 10586033 1708307 7682059 15144186 12601080 18707149 8885868 8657103 17016520
ITK PLCG1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 24412752 15975899 22847294 20237289 15623534 19690332 12163161 23933134 30131370 15184383 16126727 12730118 31196981 17389395 23331499 19534553 20519342 16081816 15215251 17372230 17420479 27221712 17148460 21760611 12952950 25916191 19427038 27941787 10586033 34429382 23109003 11564877 12029091 12941616 19412549 14568990 28644030 11709089 8657103 15951569 22649724
NCK1 FYN â—¼   DOWN_REGULATES ✅ - 52.0 1.0 ACSN 10022831 10086337 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11960372 12175651 12393695 12629515 12640133 13678960 15099563 15111329 15501236 15520864 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17496910 17673906 17883421 19414323 19449109 21372296 21378271 22064427 22461508 23390297 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8551221 8837607 9157999 9570538 9753319
SRC RASA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 23331499 11389730 1717825 16713569
SRC BTK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 19109164 23170196 8629002 29455639 10051622 8630736 26165234 9052864
ITK BTK â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 24.0 1.0 Omnipath 12445832 12573241 8629002 8630736 16497976 11598012
INSR IRS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 64.0 1.0 Omnipath 17145710 10655627 7651388 25472611 1385403 18083107 12220227 23331499 28328746 7504175 19534553 7499194 7537849 7935368 11572799 11781100 10592173 17570479 17575262 18988627 12446583 15629149 10455177 15870194 11416002 12101187 17167487 8530377 8626379 8662806 11606564 2159922 8626723 16020478 16582879