Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
EP300 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20488183
H1-2 H1-5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-5 CNTRL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-5 PDIA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-5 ALK â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA4 COL4A3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA4 HDGFL2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
OR4N5 PDIA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA4 RUBCN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ERO1A PDIA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
PDIA4 ERO1A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20802462 8075064
H1-2 CNTRL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
H1-2 PDIA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
ATF6 CALR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19659458
IRF8 BCL2L1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10430629 23677993
PDIA4 BOP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA4 DHX38 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA3 EFEMP1 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
ERBB3 FGFR1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
LDLR FLT1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6177067 17962812
LDLR FLT1 â—¼   COLOCALIZATION 2.0 0.8 intact 6177067 17962812
PDIA4 GRIPAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
IRF8 TRAF6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16484229
PDIA3 LDLR â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
PTPN11 MET â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18579758 6731904
PDIA4 MYH15 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA4 NIT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA4 PDIA3 â—¼   DISULFIDE_BOND ✅ 2.0 0.8 intact 17170699 5219449
PPIB PDIA4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA4 ZNF652 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA4 RALGAPA1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA4 RNF168 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PDIA4 RAPGEF5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
STRN3 STRN â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8213804 18782753
H2AX CALR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 20000738 16522924
PTPRN PDIA1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27880917 27432908
PDIA1 GRN â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26370502 32296183
ENPL PDIA4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 34079125
GLU2B PDIA4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 34079125
CALR GLU2B â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939629 24981860
LRRK2 EFTU â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
EFTU DCPS â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22863883 29478914
PDIA4 SDF2L â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 34079125
EP300 ATF2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24069158 10327051
CALR PDIA4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 24981860 34079125
CFTR PPIB â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31324722 17110338
CFTR PDIA3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 26618866 31324722
EMC3 PDIA4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
PDIA4 EMC7 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HDAC6 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15102857 19344692 12718889 22778253 23133622
IGF1R ERBB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 30898150 17307140
MET ERBB3 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 21918175 25326665
MATN3 PDIA4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 16287128 23956175
NENF PDIA4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22939629 34079125
PTMA PDIA4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 22863883 24981860
PTPRN PDIA4 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 27880917 27432908
FLT1 FLT4 â—¼   PHYSICAL_INTERACTION 829.0 0.82 STRING 36370105
ERO1B ERO1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PDIA3 ERO1A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 20802462 17170699
PDIA1 PDIA4 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22939629 26344197 34079125
CALR ENPL â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31536960 22939629 24981860 26344197
HDAC6 CFTR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 31501480 14675537 22069321
EMC7 EMC3 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 22119785
ERBB2 FGFR4 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 30898150 28205554 28628118
LRRK2 TTC27 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 31046837 29513927
PTPN11 ERBB2 â—¼   DEPHOSPHORYLATION ✅ - 0.84 0.84 Signor 32024694
CALR APOB â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 12397072 10513896 9694898
CFTR PDIA4 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 26618866 29924966 31324722
IGF1R INSR â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
ERO1A PDIA4 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20802462 34079125
ENPL PPIB â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24981860 22665516
PPIB GLU2B â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24981860 30021884
PDIA4 EFTU â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 22863883 32877691
PPIB CALR â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 24981860 30021884
PDIA4 DOCK3 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 32203420 30021884
HDAC6 ERBB2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31980649 20029029
ERBB3 HDAC6 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 31980649 20029029
PTPRO MET â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 28330616 19167335
INSR PTPN11 â—¼   PHYSICAL_INTERACTION 866.0 0.86 STRING 36370105
PDIA1 PPIB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 22939629 26344197 30021884
PPIB APOB â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 12397072 16713569
PDIA3 PDIA4 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17170699 24981860 34079125
TRAF6 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
FLT1 PTPN11 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
ERO1B PDIA1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 11707400 20802462 11847130
ENPL ERBB2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 23995768 8617772 25898135
ENPL APOB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12397072 9694898
PDIA4 APOB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12397072 9694898
LDLR APOB â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 12031600 24447298
CFTR GRN â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 26618866 29924966 17110338 31324722
EP300 PTMA â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 11967287 16713569 10891508
PDGFRB PTPN11 â—¼   PHYSICAL_INTERACTION 899.0 0.89 STRING 36370105
ERO1A PDIA1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 26344197 10970843 11707400 20802462 11847130
PDIA4 BCL2L1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
BCL2L1 PLD3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PDIA3 CALR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 24981860 26344197 12052826 10436013 11823531 16189514 30021884
SMARCB1 CALR â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
SMARCB1 GADD45G â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PDIA4 GADD45G â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PCSK9 LDLR â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 23085658 18250299 22081141 25613181 18753623 17435765
PTPN11 PDGFRB â—¼   PHYSICAL_INTERACTION ✅ 0.9 0.9 mint 8119896 6730513
PDIA4 PPIB â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 34079125 24981860 22665516 30021884
TRAF6 MAP3K7 â—¼   UBIQUITINATION ✅ + 0.9 0.9 Signor 18758450
ERBB2 ERBB3 â—¼   PHYSICAL_INTERACTION 916.0 0.91 STRING 36370105
H2AX PDIA4 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 20000738 34079125
ERO1B PDIA4 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HIPPIE 20802462 34079125
ERBB2 PTPN11 â—¼   PHYSICAL_INTERACTION 939.0 0.93 STRING 36370105
KRTAP10-8 KRTAP12-1 â—¼   PHYSICAL_INTERACTION 0.93 0.93 HuRI 32296183
STRN3 SUOX â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
DCPS SUOX â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
STRN SUOX â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
SUOX TTC27 â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
EMC3 EMC7 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
KRTAP10-8 KRTAP4-11 â—¼   PHYSICAL_INTERACTION 0.94 0.94 HuRI 32296183
ERBB3 ERBB2 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 22806884 25898135 30523157 9130710 21278786 15812817 20227043 16843263 10572067 19411071 19060928 8665853 10799311 8816440 17426253 17148612 21075308 12896906 15504738 23680147 23688700 23866081 22733765 7592681 21203579 25326665 24557338 23436906 30898150 7538656 25241761 25315821 11173924
LDLR PCSK9 â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
STRN STRN3 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
MAP3K7 TRAF6 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RNF168 H2AX â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19342239 22980979 31533041 18443409
ERO1A GPX7 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 21215271 23164639 18358825 16401067
ATF6 ERO1A â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 17991856 18360008 23850759 26587781
ALK PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 18320059 19223540 15710330 12522270 12531430 11684012 34301842 8041791 12721296 17483340 32076487
APOB LDLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12031600 24447298 11986215 15840700 1132787812031600 11327878
ATF6 PDIA4 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 ACSN 17991856 18360008 23850759 26587781
CALR PDIA3 â—¼   PHYSICAL_INTERACTION 8.0 1.0 ACSN 14508489 16181333 16239148 17204652 20958319 22076556 23157435 23850759
PRKCZ EPHB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
PTPN11 ERBB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 9756944 16273093 16729043 32024694
ERBB2 ERBB3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 17145710 23680147 17148612 24557338 19411071 21203579 7592681 23688700 23331499 21278786 12648465 22806884 27531070 17570479 30898150 29066975 17426253 16843263 9130710 20227043 25241761 10799311 8816440 22733765 10572067 19060928 11173924 21075308 23436906 7538656 15504738
HLA-B PTPN11 â—¼   ENZYMATIC_REACTION ✅ 6.0 1.0 ACSN 11513144 11994457 8976179 8986721 9605119 9751747
PTPN11 IGF1R â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 28065597 23331499 11779860 7642582 10082579 8895367
INSR PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 8135823 9832615 7493946 9593725
PCSK9 LDLR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 22081141 29209441 17435765 25613181 23085658 18753623 18250299
TRAF6 MAP3K7 â—¼   ENZYMATIC_REACTION ✅ 11.0 1.0 ACSN 11274345 12150927 12620219 14660645 15125833 16252010 17948050 18264787 18758450 18922473 19161412
TRAF6 MAP3K7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17145710 19675569 17947236 19843958 10882101 19521662 11259596 17079228 28024152 31885808 19112497 22924441 10094049 27501752 18922473 11518704 11809792 16517750 19232515 10702308 16410796 14633987 19820695 22851693 10921914 18758450 12496252 12609980 21822258 12242293 25963657 24434549 27249171 22643835 21245467 17965022 26038599
MAP3K7 PRKAB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16054096 16054095 15509864 19197243 17244528 18692468 15980064
PRKCZ MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 17496910 11940581 21386996 15075332 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
MST1R MET â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 14559966 16849525 21496277 12746450 19450681 8208547 23618918 21455220 8302603 17967179 21247903 1655790 12611639 15475459 26670562 16914575 33839159 10871856 33727228
PDGFRB PTPN11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 44.0 1.0 Omnipath 8622870 19690332 8041791 18083107 8538796 23331499 19534553 11684012 7530043 16189514 12721296 12522270 8959326 17287340 16094384 7688466 8226787 8119896 12531430 11266449 12681492 12614164 8183548 23397142 7691811