Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
CSNK2A1 PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20711232
FBXO9 TELO2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23263282
FBXO9 TTI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 23263282
RXFP4 TTI1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 28298427 20167430
LRRK2 RUVB2 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 23075850
CS075 TTI1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
ACM3 TTI1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD70 ATM â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VSIG1 ATR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
CD70 TTI1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
VSIG1 TTI1 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
RUVBL2 TTI1 â—¼   PHYSICAL_INTERACTION 825.0 0.82 STRING 36370105
RUVBL2 TELO2 â—¼   PHYSICAL_INTERACTION 826.0 0.82 STRING 36370105
PD1L1 ATM â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PD1L1 MTOR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194 32941674
PD1L1 ATR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
PD1L1 TTI1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TRRAP RUVB2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 28561026 28514442 26496610 33961781
TTI2 RUVB2 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 17643375 28561026 20801936
TMM51 TTI1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SCN2B ATR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
VSIG2 ATR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
CD68 TTI1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
TTI1 MTOR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22544753 20810650 20427287
SCN2B MTOR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
VSIG2 MTOR â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
SCN2B TTI1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
VSIG2 TTI1 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 33961781 28514442 26186194
LRRK2 TUBA1A â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
RUVB1 TELO2 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20371770 20801936
PRKDC TELO2 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
TELO2 RPAP3 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 24656813 20801936
POLR2E RUVBL1 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
TTI1 PRKDC â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 20810650 20371770 20427287
TTI1 TRRAP â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 20371770 26496610 20427287
RUVB2 RPAB1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17643375 20371770
RUVB2 TELO2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 17643375 20801936
TTI1 ATM â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20810650 20427287
ATM PRKDC â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 10464290 10608806
TTI1 ATR â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 20810650 20427287
RPTOR TELO2 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 23263282 24036451
MTOR TTI1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
TELO2 TRRAP â—¼   PHYSICAL_INTERACTION 863.0 0.86 STRING 36370105
RUVBL1 TTI1 â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
TTI1 RPAB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20371770 22863883
RPAP3 RPAB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 17643375 25036637 33961781 24981860 19450687 31738558 28561026
PIHD1 RPAB1 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 33961781 24981860 31738558 28515276 26186194 28514442
TELO2 ATR â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20427287 17384638 20801936 18160036 19097996
TELO2 MTOR â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 18160036 20801936
PIH1D1 URI1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
POLR2E URI1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
TELO2 PRKDC â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 18160036 20427287 20801936
RPAP3 URI1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
RUVBL1 URI1 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
TELO2 TTI2 â—¼   PHYSICAL_INTERACTION 0.87 0.87 HIPPIE 20810650 20801936
RUVBL2 URI1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
MTOR TELO2 â—¼   PHYSICAL_INTERACTION 875.0 0.87 STRING 36370105
RUVB1 TTI1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17643375 28561026 20371770 20801936
TTI1 RUVB2 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 17643375 28561026 20371770 20801936
TTI1 PIHD1 â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20371770 22863883 20801936
SMG1 RBM8A â—¼   PHYSICAL_INTERACTION 0.88 0.88 HIPPIE 20371770 19417104 16452507
RUVB1 RPAP3 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 25036637 31738558 19450687 29662061 28561026 28514442 20371770
RUVB1 TRRAP â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 26344197 22939629 26496610 11839798 28514442 20371770
PIHD1 TELO2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 22863883 24656813
TTI2 TTI1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HIPPIE 33961781 20810650 20801936
ATR TELO2 â—¼   PHYSICAL_INTERACTION 896.0 0.89 STRING 36370105
RUVB1 PIHD1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17643375 33961781 17636026 26711270 24656813 31738558 26186194 25404746 28514442 20371770
RUVB2 RPAP3 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17643375 25036637 33961781 31738558 19450687 29662061 19180575 28561026
RUVB2 PIHD1 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 17643375 33961781 26711270 17636026 24656813 31738558 28561026 26186194 25404746 28514442
CSNK2A1 TTI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23263282
TTI1 TELO2 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 20810650 20427287 20801936 22863883 20371770
ATM TELO2 â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
PIH1D1 RUVBL1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
PIH1D1 RUVBL2 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
RUVBL2 TRRAP â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
ATM ATR â—¼   PHYSICAL_INTERACTION 965.0 0.96 STRING 36370105
RPAP3 PIHD1 â—¼   PHYSICAL_INTERACTION 0.97 0.97 HIPPIE 17643375 25036637 33961781 26711270 24981860 19450687 24656813 26344197 31738558 22939629 29662061 28561026 26186194 25404746 28514442 21078300
RICTOR MTOR â—¼   PHYSICAL_INTERACTION ✅ 0.97 0.97 mint 24036451
MTOR RICTOR â—¼   COLOCALIZATION ✅ 0.97 0.97 mint 21045808 8088164
RPAP3 RUVBL1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
RPAP3 RUVBL2 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
TELO2 TTI1 â—¼   PHYSICAL_INTERACTION 979.0 0.97 STRING 36370105
RPTOR MTOR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 24036451
MTOR RPTOR â—¼   COLOCALIZATION ✅ 0.98 0.98 mint 21045808 8088164
PIH1D1 RPAP3 â—¼   PHYSICAL_INTERACTION 986.0 0.98 STRING 36370105
MTOR RPTOR â—¼   PHOSPHORYLATION ✅ + 0.98 0.98 Signor 19346248
RUVBL1 TRRAP â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
RBM8A SMG1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
RUVBL1 RUVBL2 â—¼   PHYSICAL_INTERACTION 997.0 0.99 STRING 36370105
RUVB2 RUVB1 â—¼   PHYSICAL_INTERACTION 1.0 1.0 HIPPIE 33961781 11080158 20211142 18358808 22939629 28561026 10966108 26264872 22863883 17643375 25636407 26344197 18087039 25437307 20603076 29323271 32296183 17353931 25416956 20371770 28514442 29892012 19433865 17636026 16230350 17157868 17721549 10524211
ATR ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15510216 10608806 17478428 17124492
TELO2 ATM â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 18160036
ATM PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 47.0 1.0 Omnipath 17189255 12231622 17303408 24492479 10464290 22230547 15677476 16822724 28985363 29088817 16163361 32868446 19549901 25818648 22923485 19103741 17570479 27939942 19808981 23847781 22355272 24714417 15964794 21376743 31983282 25224041 16908529 12607003 19244120 17525332 15459660 34249431 28107384 12186630 25714019 11877377 26553138 27568553 19535303 15507430 26578593
ATR PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 12186630 22592045 22057367 24500207 18077418 16908529 15507430 29309644
LRRK2 CSE1L â—¼   PHYSICAL_INTERACTION 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 CSE1L â—¼   SHARES_COMPLEX 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
LRRK2 CSE1L â—¼   ENZYMATIC_REACTION ✅ 20.0 1.0 ACSN 10089876 10811803 10898494 11030334 11148124 11262396 11274345 11402342 11406367 14627704 17593948 17662023 18287025 19836308 21709260 21983832 7650486 8068174 9374532 9973469
CSNK2A1 TELO2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 20864032 24656813 23263282
MTOR RPTOR â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
MTOR RICTOR â—¼   PHYSICAL_INTERACTION 41.0 1.0 ACSN 10722653 11274345 11756498 12408816 12906785 16469695 16556040 16678438 17461779 17680028 18000759 18481918 18492954 18566586 18570873 18925875 19022819 19027299 19143635 19151919 19446321 19568798 19706736 19720745 20027184 20338997 21157483 21474067 21533173 21621563 21708191 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
MTOR RICTOR â—¼   SHARES_COMPLEX 41.0 1.0 ACSN 10722653 11274345 11756498 12408816 12906785 16469695 16556040 16678438 17461779 17680028 18000759 18481918 18492954 18566586 18570873 18925875 19022819 19027299 19143635 19151919 19446321 19568798 19706736 19720745 20027184 20338997 21157483 21474067 21533173 21621563 21708191 21981924 23087689 24795729 24973821 25002027 25730849 26159692 27331412 28216025 9069260
MTOR RPTOR â—¼   SHARES_COMPLEX 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
PTP4A3 MTOR â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 17409395 19440036 19945467 20609352 21084277 23691193 24030100 24376839 24696260 25136802 26597054 27328425 27572739
MTOR RPTOR â—¼   ENZYMATIC_REACTION ✅ 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
MTOR RPTOR â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
TTI1 MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20427287 20810650
TELO2 MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 20427287 18160036
RPTOR MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 139.0 1.0 Omnipath 15268862 24403073 20427287 22258093 21321085 19446321 15467718 19875983 17461779 12665511 12719976 16631613 21045808 21177249 23911927 24337580 25446900 24516643 18614546 12718876 12747827 16603397 17043309 18519641 22544753 25007995 27043084 19145465 23953116 19619545 16919458 24375676 15459249 16837165 16847060 25332233 12150926 22424946 26348909 12150925 18955708 20381137 22356909 17386266 17565979 18030348 16354680 20169205 19114562 21071439 27329724 35561222 16798736 15809305 22493283 17277771 15661536 16962653 1683716516603397 17604271 18676370 16183647 18505677 23297343 23872070 24036451 15066126 18570873 21614075 18722121 12408816 17599906
PTP4A3 RPTOR â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 17409395 19440036 19945467 20609352 21084277 23691193 24030100 24376839 24696260 25136802 26597054 27328425 27572739
PRKDC ATM â—¼   KO_DOWN_REGULATES ✅ - -1.5 1.49 PKG 28854368
ATM ATM â—¼   KO_DOWN_REGULATES ✅ - -2.25 2.25 PKG 28854368
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368