Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list

Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
IAPP RAMP3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 25409149 24169554
IDE APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
BACE2 APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
SNCA APP â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FOXO1 KLF4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18375530
HNF1A IAPP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14521933 15566941
KLF4 IAPP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12919939 14675715
NRF1 IAPP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14747477 15992771
JUN NFAT5 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18056707
PAX6 PCSK2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19223471 24047795
APP SNCA â—¼   PHYSICAL_INTERACTION 811.0 0.81 STRING 36370105
PAX6 CDX2 â—¼   PHYSICAL_INTERACTION 0.85 0.85 HIPPIE 10506141
APP BACE1 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
RAMP1 IAPP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 1331173 9620797 2608057
RAMP2 IAPP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 1331173 9620797 2608057
RAMP3 IAPP â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 1331173 9620797 2608057
CDX2 CDX1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 23382958 11997022 19725873
TFAP2A BACE1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14701757 15059977
IAPP CALCR â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 1331173 9620797 2608057
JUN CDX2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 20351696 9926923 24953186
CDX2 KLF4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11521200 23202735
FOXA2 IAPP â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 24627476 15566941 11875061
IAPP IDE â—¼   PHYSICAL_INTERACTION 927.0 0.92 STRING 36370105
APP IDE â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
IAPP RAMP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 24169554 10385705
IAPP RAMP2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 24169554 16531504
JUN APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8063812 11677255 8015372
TFAP2A APP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 17651731 9048735
BACE2 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 10936190 10605825 8764598 15178331 20418918 10931940
BACE1 APP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 30538620 22801501 10677483 20418918 12901838 10531052 10931940 32814053 28923680 28869759 19251705
IAPP CALCR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 9487987 24169554 10342886 12529937
JUN FOXA2 â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 11274345 16054035 16396903 16406505 16880536 17000779 17439715 18813803 19190345 19219074 20107231 26587781 8545107
PCSK1 IAPP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10931181 8557106 3053705 11246872
PCSK2 IAPP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 10931181 8557106 3053705 11246872
PAX6 PCSK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19034419 23056534 24047795