Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
SP3 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12200429 20096088
CSNK2A1 PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20711232
SP1 FGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15158147 19302822
FGFR3 HOXB7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
FGFR3 USF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
USF1 GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 1427648 2659342
HOXA5 HOXC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA5 HOXD4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA5 HOXC5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA5 HOXB5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA5 HOXA6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA5 HOXA7 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA5 HOXB6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA6 HOXB6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA6 HOXB7 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA6 HOXB4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA6 HOXC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA6 HOXC5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA6 HOXD4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA6 HOXC4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA6 HOXB5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA6 HOXA7 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA7 HOXB4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA7 HOXC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA7 HOXB7 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA7 HOXC4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA7 HOXD4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA7 HOXC5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA7 HOXB5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA7 HOXB6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB4 HOXC5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB4 HOXB5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB4 HOXC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB4 HOXC4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB4 HOXD4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB4 HOXB6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB5 HOXC5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB5 HOXC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB5 HOXB6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB5 HOXD4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB5 HOXB7 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB6 HOXD4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB6 HOXC5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB6 HOXC4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB6 HOXC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SPRED1 HOXB7 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HOXB7 HOXC5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB7 HOXD4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB7 HOXC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SP3 HOXB7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12697323
SP1 HOXB7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12697323
HOXB7 PRKDC â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17308091
SPRED1 HOXC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HOXC4 HOXC5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXC4 HOXC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXC4 HOXD4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXC5 HOXC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXC5 HOXD4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXC6 HOXD4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
SP1 NPPA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20874724 9295358
SP3 PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12657578 15777284
PBX2 PBX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6547613 9482739
HOXA5 PBX1 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
ENSG00000273049 HOXB5 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ENSG00000273049 HOXB4 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ENSG00000273049 HOXC5 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ENSG00000273049 HOXB7 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ENSG00000273049 HOXC6 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ENSG00000273049 HOXC4 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ENSG00000273049 HOXA5 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ENSG00000273049 HOXA7 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ENSG00000273049 HOXB6 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ENSG00000273049 HOXA6 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ENSG00000273049 HOXD4 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
SP3 SP1 â—¼   PHYSICAL_INTERACTION 0.81 0.81 HIPPIE 12414801 11517158 10825178 16734381 9329821 23825960 12200149 15247906
HOXA5 HOXB4 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
HOXA5 HOXC4 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
HOXB4 HOXB7 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
HOXB7 HOXC4 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
HOXA5 HOXB7 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
HOXB6 HOXB7 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
PRKDC PARP1 â—¼   PHYSICAL_INTERACTION 0.84 0.84 HIPPIE 20085707 16794079 21575865 9398855
SMARCA4 SP1 â—¼   PHYSICAL_INTERACTION 846.0 0.84 STRING 36370105
FGF2 FGFR3 â—¼   PHYSICAL_INTERACTION 850.0 0.85 STRING 36370105
HOXB5 HOXC4 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
SP1 SP3 â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
PARP1 XRCC5 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
HOXC5 PBX2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
SP1 PRL â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11694349 9349726 9360988
SP1 CSNK2A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10849443 19027835
USF1 HOXB7 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1677811 12697323
XRCC5 PRKDC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 26496610 22404984 15520013 21679440 26446488 26344197 17308091 15941674 28154079 16857680 20711232 19303849 20023628 15758953 20085707 10750018 10446239 33005030 9312071 28345663 12393188
XRCC6 PRKDC â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 8422676 20711232 19303849 26175416 28345663 30585729 17308091 22939629 26496610 10750018 15941674 33005030 21969602 15520013 10064605 21575865 26446488
SP3 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9329821 15247906 10825178
XRCC6 XRCC5 â—¼   PHYSICAL_INTERACTION 0.9 0.9 HIPPIE 33961781 24981860 22939629 15367688 26496610 26774286 21172662 11196700 15520013 22863883 21679440 17159921 30021884 14681455 26446488 26344197 10207052 30585729 17308091 11493912 10757784 10219089 10984620 19118032 12145306 32296183 28035050 19177010 18809223 21454661 15910003 10783163 28514442 21070772 25574025 15023334 7699019 10750018 10446239 22451927 33005030 9488450 17283121 19906305
PARP1 XRCC6 â—¼   PHYSICAL_INTERACTION 904.0 0.9 STRING 36370105
HOXA5 PBX2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
HOXB5 PBX2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
XRCC5 XRCC6 â—¼   CORRELATES + 0.92 0.92 CCLE 31978347
XRCC6 PRKDC â—¼   RELOCALIZATION ✅ + 0.93 0.93 Signor 19133841
XRCC5 XRCC6 â—¼   PHOSPHORYLATION ✅ 0.96 0.96 mint 10783163 5212534
PRKDC XRCC6 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
PRKDC XRCC5 â—¼   PHYSICAL_INTERACTION 982.0 0.98 STRING 36370105
XRCC5 XRCC6 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
SP1 CREBBP â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23297421 20096088 9765204 21191649 21464950 12200429 20130956 12169688 15576380 15184875 15713621 18571793
CSNK2A1 NFKBIA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 32.0 1.0 Omnipath 10783893 16007147 9721103 11673497 12138192 10723127 7796813 8657113 8622692 10421793 12167702 12403772 8668171 8657102 10398585 8601309 9214631
CSNK2A1 HOXB7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 11290787
CSNK2A1 SP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 9153193
CSNK2A1 PPP1R1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 2557337
HOXB7 FGF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 8756643 9681827 21183939 16862184
FGF2 FGFR3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 22298955 16597617 866304410574949 9045692 15780951 10574949 8663044 25772309
SP1 GH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 1427648 8754847 2181288 2659342 10698168 2033067
USF1 HOXB4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 11085749 12791656 23754954
SP1 PARP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 9428683 9493965 17003407 17961220 11278663 12657578 15777284
PRKDC USF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 20817607 26490400 23219531 19303849
SP3 SP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 21554857 12509426 9632663 10362515 19223508 15857802 20096088 16806531 15854045 15118068 9788252 12773549 16617124 11517158 12554796 9666093 15869407 12888570 11287330 15541732 8845379 16574784 8070411
PRKDC PRKDC â—¼   KO_DOWN_REGULATES ✅ - -4.22 4.21 PKG 28854368
PARP1 PARP1 â—¼   KO_DOWN_REGULATES ✅ - -7.28 7.27 PKG 28854368