Protein list:

Seperate proteins by space | Example

Select nodes using shift click or drag to add to this list
Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

Note this may take some time with > 30 proteins
Filter Graph:

0.5
Layout:
  🔂

Click a node or edge for more data...
Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
TP53 BCL2L14 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
ZNF408 DVL3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
FOXA2 TH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23637192 17596284
PGR FOXO1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18391971
HOXA4 TH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12670698
HOXA5 HOXC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA5 HOXD4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA5 HOXC5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA5 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HOXA5 HOXB5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA5 HOXA6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA5 HOXA7 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA5 HOXB6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA5 PGR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10875927
HOXA5 TH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12670698
HOXA5 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19918835
HOXA6 HOXB6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA6 HOXB7 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA6 HOXB4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA6 HOXC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA6 HOXC5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA6 HOXD4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA6 HOXC4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA6 HOXB5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA6 HOXA7 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA7 HOXB4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA7 HOXC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA7 HOXB7 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA7 HOXC4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA7 HOXD4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA7 HOXC5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA7 HOXB5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXA7 HOXB6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB4 HOXC5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB4 HOXB5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB4 IGFBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12489992
HOXB4 HOXC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB4 HOXC4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB4 HOXD4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB4 HOXB6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB5 HOXC5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB5 HOXC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB5 HOXB6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB5 HOXD4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB5 HOXB7 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB6 HOXD4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB6 HOXC5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB6 HOXC4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB6 HOXC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB7 HOXC5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB7 HOXD4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXB7 HOXC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HTT HOXC4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HOXC4 HOXC5 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXC4 HOXC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXC4 HOXD4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXC5 HOXC6 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXC5 HOXD4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
HOXC6 HOXD4 â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TWIST1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
PICK1 HTT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
TP53 IGFBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11672436 18056423
TP53 MLH1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15781865
NOTCH1 SOX2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17537801
PBX2 PBX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 6547613 9482739
TP53 TH â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16133124 19618851
TP53 TWIST1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18504427 20689556
HOXA5 PBX1 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
ENSG00000273049 HOXB5 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ENSG00000273049 HOXB4 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ENSG00000273049 HOXC5 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ENSG00000273049 HOXB7 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ENSG00000273049 HOXC6 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ENSG00000273049 HOXC4 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ENSG00000273049 HOXA5 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ENSG00000273049 HOXA7 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ENSG00000273049 HOXB6 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ENSG00000273049 HOXA6 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
ENSG00000273049 HOXD4 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
FOXO3 TP53 â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
HOXA5 HOXB4 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
HOXA5 HOXC4 â—¼   PHYSICAL_INTERACTION 812.0 0.81 STRING 36370105
ERP44 BCOR â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 33961781 28514442
HOXB4 HOXB7 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
HOXB7 HOXC4 â—¼   PHYSICAL_INTERACTION 820.0 0.82 STRING 36370105
HOXA5 HOXB7 â—¼   PHYSICAL_INTERACTION 822.0 0.82 STRING 36370105
SOX2 KDM6A â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 22801502 35140242 28794006
HOXB6 HOXB7 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
HOXB5 HOXC4 â—¼   PHYSICAL_INTERACTION 853.0 0.85 STRING 36370105
FLT4 KDR â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
HOXC5 PBX2 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
HOXB5 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.89 0.89 HuRI 32296183
FOXO3 DDIT3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18226221
RARB HOXA5 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 17804711
HOXA5 PTN â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15757903
HOXA5 MLH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 16756717
TP53 MLH1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18431400 15781865
NOTCH1 SMAD1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 14597575 23331499 14500836
ZNF408 ZRANB1 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
HOXA5 PBX2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
HOXB5 PBX2 â—¼   PHYSICAL_INTERACTION 0.91 0.91 HuRI 32296183
TWIST1 BMI1 â—¼   PHYSICAL_INTERACTION 42.0 1.0 ACSN 11283614 11528470 12490555 13130303 14623871 15140942 15574337 15640618 15980428 16510505 16716598 16831886 17055429 17093497 17332325 17537911 17550342 17936558 17987801 18297062 18832382 19208835 19284610 19336515 20027199 20713526 20731704 20818389 21199805 21317430 21383063 21502402 21678481 21685941 21733352 2191300 21919891 22406545 22796940 22945800 7768934 9278421
ZEB1 BMI1 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 10048576 16556862 17012742 17486063 19208835 19839049 19935649 20589835 20702634 20706219 21051859 21081489 21159887 21224848 22286765 22439866 225147423 22514743 22945800 24335145 28212565 9811054
TWIST1 BMI1 â—¼   UP_REGULATES ✅ + 42.0 1.0 ACSN 11283614 11528470 12490555 13130303 14623871 15140942 15574337 15640618 15980428 16510505 16716598 16831886 17055429 17093497 17332325 17537911 17550342 17936558 17987801 18297062 18832382 19208835 19284610 19336515 20027199 20713526 20731704 20818389 21199805 21317430 21383063 21502402 21678481 21685941 21733352 2191300 21919891 22406545 22796940 22945800 7768934 9278421
KDR FLT4 â—¼   PHYSICAL_INTERACTION 34.0 1.0 ACSN 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15308668 15501236 15520864 15573129 16000375 16002046 16076871 16530705 16572188 17086423 17883421 18835194 19414323 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 8837607 9157999 9570538 9753319
KDR FLT4 â—¼   SHARES_COMPLEX 34.0 1.0 ACSN 10022831 11166270 11960372 12629515 13678960 15099563 15111329 15308668 15501236 15520864 15573129 16000375 16002046 16076871 16530705 16572188 17086423 17883421 18835194 19414323 19454690 21372296 22064427 22461508 22464172 23390297 24217602 24346288 25922287 26201938 8837607 9157999 9570538 9753319
FOXO3 FOXO1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19244250 16100571 18202312 23509296 19690465
FOXO1 IGFBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10385407 10358014 10358076 17609436 15200677 11733864 23603247 11570877 17426286 12493691 21401636 17923482 10702299 12163409 16690806 24174424 15987820 10973497 17341623
FOXO1 IGFBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 18391971 10913147 10358076 9707622 18056423 10358075 10102273 18985696 12493691
TP53 HTT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22399227 15996546 16978870 16278683
TP53 HTT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 18431400 32814053 16713569 10823891
PGR IGFBP1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12489992 9178756 10459849 15987820 11117526
ZEB1 SOX2 â—¼   UP_REGULATES ✅ + 22.0 1.0 ACSN 10048576 16556862 17012742 17486063 19208835 19839049 19935649 20589835 20702634 20706219 21051859 21081489 21159887 21224848 22286765 22439866 225147423 22514743 22945800 24335145 28212565 9811054
TWIST1 ZEB1 â—¼   UP_REGULATES ✅ + 37.0 1.0 ACSN 11283614 11528470 12490555 13130303 14623871 15140942 15574337 15640618 15980428 16510505 16716598 16831886 17055429 17093497 17332325 17537911 17550342 17987801 18297062 18832382 19208835 19284610 19336515 20027199 20713526 20731704 20818389 21199805 21317430 21502402 21733352 2191300 21919891 22406545 22945800 7768934 9278421
TP53 KDR â—¼   KO_UP_REGULATES ✅ + 1.12 1.12 PKG 28854368
TP53 NOTCH1 â—¼   KO_DOWN_REGULATES ✅ - -1.46 1.45 PKG 28854368