AURKA
|
PPP1R1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11551964
|
CSNK2A1
|
CSNK2B
|
â—¼ PROXIMITY
|
|
|
2.0
|
0.8
|
intact
|
29997244
20178071
|
DLGAP4
|
PPP1R1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
HSPB6
|
PPP1R1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18948619
|
PRKACB
|
PDE4B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8663227
9099992
|
PRKACA
|
PDE4B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8663227
9099992
|
PRKACG
|
PDE4B
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
8663227
9099992
|
PRKACG
|
PPP1R1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
28553197
7826384
|
PPP3R1
|
PPP1R1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
6330098
2153935
|
ROBO2
|
PPP1R1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16169070
5217955
|
PPP3CA
|
PPP1R1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
10217279
12065642
|
PRKAR1A
|
PRKACA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
24855271
1252328
|
PRKAR1B
|
PRKACA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
26687711
32296183
|
EXO5
|
PPP1R1B
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
0.81
|
0.81
|
PKG
|
28854368
|
PRKACA
|
PRKAR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
841.0
|
0.84
|
STRING
|
36370105
|
PRKAR1B
|
PRKACA
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
-
|
0.84
|
0.84
|
Signor
|
26687711
|
PPP3R1
|
PPP3CA
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.87
|
0.87
|
mint
|
7295928
19896943
|
PRKACG
|
PRKAR1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
PRKAR2A
|
PRKAR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
PRKAR1B
|
PRKACB
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
-
|
0.87
|
0.87
|
Signor
|
26687711
|
PPP1CA
|
PPP1CB
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
PPP1CB
|
PPP1CC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
CSNK2A1
|
CSNK2A2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
PRKACA
|
PRKAR2B
|
â—¼ PHOSPHORYLATION
|
✅
|
+
|
0.88
|
0.88
|
Signor
|
15187164
|
PRKACB
|
PRKAR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
888.0
|
0.88
|
STRING
|
36370105
|
PRKACG
|
PRKAR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.88
|
STRING
|
36370105
|
PPP1CA
|
PPP1CC
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.89
|
STRING
|
36370105
|
PRKACB
|
PRKAR2A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.89
|
STRING
|
36370105
|
PPP1CA
|
AURKA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
11039908
11551964
|
CDK5
|
PPP1CA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
intact
|
010002200
11320080
8286802
|
PPP1R1B
|
PPP1CC
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
9108011
6087160
10604473
|
PRKACB
|
PRKAR1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
910.0
|
0.91
|
STRING
|
36370105
|
PRKACB
|
PRKAR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
918.0
|
0.91
|
STRING
|
36370105
|
CSNK2A2
|
CSNK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
0.91
|
0.91
|
HuRI
|
32296183
|
CDK5R1
|
CDK5
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.93
|
0.93
|
mint
|
23543736
|
CSNK2B
|
PPP1R1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
941.0
|
0.94
|
STRING
|
36370105
|
CDK5
|
CDK5R1
|
â—¼ PHOSPHORYLATION
|
✅
|
-
|
0.94
|
0.94
|
Signor
|
18326489
|
PRKACA
|
PRKAR1A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
968.0
|
0.96
|
STRING
|
36370105
|
PRKACA
|
PRKAR1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
972.0
|
0.97
|
STRING
|
36370105
|
CSNK2B
|
CSNK2A1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.98
|
0.98
|
mint
|
36833176
|
PRKACG
|
PRKAR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
PPP3CA
|
PPP3R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
PRKACA
|
PRKAR2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
993.0
|
0.99
|
STRING
|
36370105
|
CDK5
|
CDK5R1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
996.0
|
0.99
|
STRING
|
36370105
|
CSNK2A1
|
CSNK2B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
0.99
|
STRING
|
36370105
|
PRKACA
|
AURKA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
22.0
|
1.0
|
Omnipath
|
23861900
16222244
16246726
33744274
29764989
26165940
11039908
17545617
27242098
26481147
28869606
26134678
33988677
26831064
33760847
16083426
17895985
|
CSNK1D
|
CDK5
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
10500146
|
CDK5
|
CDK5R1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
33.0
|
1.0
|
Omnipath
|
11583627
23602568
15689152
11389014
17036052
25076872
21220307
15890360
16189514
23979715
26186194
17591690
17762160
14521924
20133653
22654103
28637746
12223541
23543736
18326489
28077789
17121855
|
CDK5
|
PPP1CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
12202491
9122166
17202132
|
CDK5
|
PPP1R1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
11013232
16353915
24560149
10604473
21848865
25196634
29082320
21904525
21811441
16040813
24555476
12237154
19465087
29354053
26979514
17194217
11050161
20169176
17535922
14744247
12065642
22820052
18808062
19580849
15464122
|
CDK5R1
|
PPP1R1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
28881851
26488498
22952905
12956723
20156529
26979514
11050161
|
CSNK2A2
|
CSNK2A1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
26186194
27705803
25519132
19011756
26496610
25852190
23455922
|
CSNK2A1
|
HOXB7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
11290787
|
CSNK2A1
|
PPP1R1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
2557337
|
CSNK2A2
|
PPP1R1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
17570479
2557337
|
PRKACA
|
HSPB6
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
18.0
|
1.0
|
Omnipath
|
12133854
18790732
22731613
10196226
11749379
26443497
27046040
22794279
19850943
25446653
20833797
21334344
12716456
17084643
15829720
|
PRKACA
|
PDE4B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
12023945
12441002
|
PPP1R1B
|
PPP1CA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
11440854
9108011
19651774
10604473
|
PRKACA
|
PPP1R1B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
15.0
|
1.0
|
Omnipath
|
11717349
1494946
10604473
15726118
15536496
6319628
6296685
3339428
17194217
|
PRKACA
|
PPP2R5D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
9688562
17110335
17301223
29294329
|
PRKAR1A
|
PRKACA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
13.0
|
1.0
|
Omnipath
|
17145710
15655353
17353931
26687711
11834733
24855271
32296183
24700472
9405392
25477193
|
PRKACA
|
PRKAR2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
27107012
15187164
32296183
17148597
21795691
33608270
25477193
|
RAD18
|
PPP1R1B
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.21
|
1.21
|
PKG
|
28854368
|
RAD18
|
PPP1CC
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-1.37
|
1.36
|
PKG
|
28854368
|
RAD18
|
PPP1CA
|
â—¼ KO_UP_REGULATES
|
✅
|
+
|
1.72
|
1.72
|
PKG
|
28854368
|
RAD18
|
RAD18
|
â—¼ KO_DOWN_REGULATES
|
✅
|
-
|
-4.39
|
4.38
|
PKG
|
28854368
|