Protein list:

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
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Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ARAF MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18039929
ARAF MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18039929
GRB2 BAD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
MAPK9 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14673001 17555943
CDK2 WEE1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 1396589 11585773
DNAJB11 DDX42 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YWHAZ EGFR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217069 15225635
EGFR TLN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218056 16273093
EGFR YWHAZ â—¼   COLOCALIZATION 2.0 0.8 intact 5217069 15225635
GRB2 HSPA5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 NCL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 IQGAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 CFL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 SERPINH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 GRWD1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 PPP1R12A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 HSPA8 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 XRCC6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 CORO1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 CAMK2D â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 SPTBN1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
MAPK3 GRB2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 7739560 8816480
MAPK1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8994038
FGFR1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9480847 16713569
YWHAZ IQGAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
CDH2 IQGAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17098867 0607299103
IQGAP1 PXN â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 15263019 22573807
RAF1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 20674547 15664191
MAPK1 RPS6KA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
MAPK1 RPS6KA3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
ESR1 MAPK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23250869 22430216
RPS6KA1 MAPK1 â—¼   PROXIMITY 2.0 0.8 intact 29997244 20178071
PRKCB MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8903320 10327068
PPP1CA MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12624094 12840032
MAPK1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15263086 15466214
MAPK1 RSPH3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19684019
RAF1 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 20674547 15664191
MAPK3 RPS6KA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
MAPK3 RPS6KA3 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
PPP1CA MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 12624094 12840032
PRKCB MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8903320 10327068
MAPK3 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15263086 15466214
GTF3C5 MTOR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20543138 1005188107
YWHAZ MTOR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
MTOR PDPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214238 11438723
NUAK1 LATS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 7717767 19927127
WEE1 PLK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15070733 15037762
CDC25C PLK1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 11897663 8703070
PLK2 PLK1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 0904229106 19706541
PLK1 G6PD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29138396
PDPK1 PRKCD â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12840507 9889098
ESR1 PRKCD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22430216 18414489
SYK PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29352133 22265677
SETD7 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18784729
SNRNP40 EPB41L2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
TLN1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
XRCC6 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
LRRK2 DYRK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
AKAP10 PRKAR1B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9065479 9326583
PRKAR1B AKAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9065479 9326583
PRKAR1B PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 26687711 32296183
HSPA8 PRKAA2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 26902588 25961502
JUP FRMD5 â—¼   COLOCALIZATION 2.0 0.8 intact 22846708 8385346
PPIB SERPINH1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PIK3CB SYK â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 15536084 11907067
SYK PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9590268
FN1 ITGB1 â—¼   COLOCALIZATION 2.0 0.8 intact 21985969 8208414
PTP4A3 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19930715 16472776
CD247 CSK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 15489916 15489910
CD247 PIK3CB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 12869549 15536084
PXN FN1 â—¼   COLOCALIZATION 2.0 0.8 intact 21985969 8208414
PRKCZ RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16189514 10620507
YWHAZ MCM3 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
KSR1 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9115393 9858547
LRRK2 LATS1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 29513927 201700444
ROCK1 PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19306866
PDPK1 PRKCB â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12840507 9889098
PDPK1 PRKCZ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12840507 9889098
ILK PDPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11313365
ITGA1 ILK â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 19397781 26148229
ITGA1 PTK2 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 ACSN 19397781 26148229
CDK4 PTK6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 25733683 18719096
YWHAZ PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23331499 10620507
PRKCZ NCL â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9388266 16189514
PRKCZ MAPK9 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18667433 17646398
FN1 PTK2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 11476890 16919435
CREB1 G6PD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17273168 20103717
CREB1 OGA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 17720252 17905638
CHMP4B UBE2I â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
ESR1 GNB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19170076 18414489
YWHAZ RPL6 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
AKAP10 PRKACA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9065479 9326583
PRKAR1A PRKACA â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 24855271 1252328
CREM PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18721873 12533437
PRKACA AKAP12 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 14657015
PRKACA MAP1LC3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 20713600
PRKAR2A AKAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218560 16642035
PRKAR2A AKAP12 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218560 16642035
PRKAR2A AKAP5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5218560 16642035
AKAP10 PRKACB â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9065479 9326583
AKAP10 PRKACG â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9065479 9326583
PRKACG AKAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9065479 9326583
PRKACG PPP1R1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 28553197 7826384
PRKAR2B AKAP1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9065479 9326583
NCL ARFGEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 18292223 0712387105
ARFGEF2 ARFGEF1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 19332778 0901558106
FAM20C NCL â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
HSPA8 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
ESR1 HSPA8 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11085516
MLXIPL PPARA â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16936198 21282101
KHDRBS1 RBFOX2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 22365833 8293266
MLC1 HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
HSPB1 ANP32B â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AKAP10 PRKAR2B â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 9065479 9326583
PRKAR1A AKAP10 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16189514 5217968
YWHAZ CFL1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5215799 12361576
MAPK7 RPS6KA1 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
H1-2 G6PD â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
PRKAG1 ACACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 16326698 9029219
SET YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
RPS6KA3 MAPK7 â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12832467 16626623
H1-2 AKAP11 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
YWHAZ PPP1R12A â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 8008120 18094049
H1-2 MAP4K5 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
SPTBN1 YWHAZ â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5217040 15161933
RBFOX2 RBFOX1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16713569 5218676
H1-4 H1-2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 000924 30021884
EGFR JUP â—¼   PHYSICAL_INTERACTION 803.0 0.8 STRING 36370105
CDK2 MCM3 â—¼   PHOSPHORYLATION ✅ + 0.8 0.8 Signor 21965652
ITGA4 YWHAZ â—¼   PHYSICAL_INTERACTION 808.0 0.8 STRING 36370105
GSK3B CCNE1 â—¼   PROTEIN_INTERACTION 0.81 0.81 HIPPIE 25241761 14536078 8861947
ILK PXN â—¼   PHYSICAL_INTERACTION 814.0 0.81 STRING 36370105
AKAP5 PRKACB â—¼   PHYSICAL_INTERACTION 818.0 0.81 STRING 36370105
BRD7 C1QBP â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 30940648 32877691
AHSA1 EGFR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20029029 31980649
ADRM1 EGFR â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 20029029 31980649
EGLN3 ACACA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 26972000 33961781
GRB2 CSK â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31980649 21706016
ESR1 HUWE1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 25604459
SSRP1 MCM3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21055985 16902406
PGAM5 CUL3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 21145461 17046835
LRRK2 HSPB1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24725412 29519959
LRRK2 ADRM1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31046837 24947832
CDK4 JAK3 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 26186194
ESR1 CTBP1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 23403292 31527615
ESR1 SUZ12 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 31527615 26389696
ESR1 VAPA â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 19805454 31527615
MEPCE DDX42 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 24981860 17643375
MEPCE SET â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 17643375 29845934
MAPK3 HSPB1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 25241761 21575178 8774846
TULP3 MCRS1 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33187986 33961781
ARAF YWHAZ â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
BRD7 GTF3C5 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
PXN TLN1 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
PTK2 YES1 â—¼   PHYSICAL_INTERACTION 837.0 0.83 STRING 36370105
ESR1 GNL3 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 21182205 31527615
GRB2 HSPB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31980649 12577067
CCNE1 CDK4 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 9716181 28628118 28205554
ESR1 GRWD1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
ESR1 SET â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31527615 20348541
AKAP3 AKAP4 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 12606363
PRKACA PRKAR2A â—¼   PHYSICAL_INTERACTION 841.0 0.84 STRING 36370105
LLGL2 PRKCZ â—¼   PHYSICAL_INTERACTION 842.0 0.84 STRING 36370105
CDK2 MCM3 â—¼   PHYSICAL_INTERACTION 843.0 0.84 STRING 36370105
ITGA4 ITGB1 â—¼   PHYSICAL_INTERACTION 844.0 0.84 STRING 36370105
MAPK1 RAF1 â—¼   PHYSICAL_INTERACTION 847.0 0.84 STRING 36370105
PRKAR1B PRKACA â—¼   PHYSICAL_INTERACTION ✅ - 0.84 0.84 Signor 26687711
PRKCZ PRKCI â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24375676
CREM CREB1 â—¼   PROTEIN_INTERACTION 0.85 0.85 HIPPIE 7809053 16189514 22531917 25609649
CCNE1 CUL3 â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
AKAP10 PRKAR2A â—¼   PHYSICAL_INTERACTION 854.0 0.85 STRING 36370105
MCM3 CDK2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 15232106 16189514 21965652
HUWE1 HSPB1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 25147182 25277244
PLK1 CDC25C â—¼   PHYSICAL_INTERACTION ✅ 0.86 0.86 mint 14532005 5216753
XRCC6 SSRP1 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 28514442 30585729
ILK ACACA â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 17353931 23455922
HSPB1 G6PD â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21157431 26344197
MAPK3 RPS6KA3 â—¼   PHYSICAL_INTERACTION 861.0 0.86 STRING 36370105
C1QBP PRKCZ â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
CUL3 UBE2M â—¼   PHYSICAL_INTERACTION 865.0 0.86 STRING 36370105
AKAP1 PRKAR2B â—¼   PHYSICAL_INTERACTION 867.0 0.86 STRING 36370105
ARAF RAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 31980649 34017080 20130576
EGFR RAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 24658140 25402006 31980649
GRB2 DOCK4 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 28514442 31980649 21988832 21706016 33961781
ILK RAF1 â—¼   PROTEIN_INTERACTION 0.87 0.87 HIPPIE 23455922 26496610 25852190
ITGB1 PXN â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
AKAP1 PRKAR2A â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
EGFR YWHAZ â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
GRB2 PTK2B â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
PRKACG PRKAR1B â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
VAPA VAPB â—¼   PHYSICAL_INTERACTION 874.0 0.87 STRING 36370105
BAD RAF1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
ITGB1 TLN1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
FN1 ITGB1 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
PRKAR2A PRKAR2B â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
EGFR HSPA8 â—¼   PHYSICAL_INTERACTION 878.0 0.87 STRING 36370105
PRKAA2 PRKAR1B â—¼   PHYSICAL_INTERACTION 0.87 0.87 HuRI 32296183
PRKAR1B PRKACB â—¼   PHYSICAL_INTERACTION ✅ - 0.87 0.87 Signor 26687711
YWHAZ ARAF â—¼   PHYSICAL_INTERACTION ✅ 0.88 0.88 mint 8009399 19933840
CDK2 PGAM5 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 23455922 26496610
PTK6 EGFR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 8940083 22973453 16273093
ESR1 EGFR â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 16713569 28065597 20935677 11887937 17284441
EGFR HSPB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24189400 23397142 15657067
PLK1 WEE1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 32707033 25659891 15070733
XRCC6 SET â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 22863883 27626385 30585729
CUL3 CCNE1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 31636116 27477274 10500095 17192413
ILK HSPB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 17353931 25852190
ESR1 HSPA8 â—¼   PHYSICAL_INTERACTION 880.0 0.88 STRING 36370105
GRB2 PTK2 â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
GRB2 KHDRBS1 â—¼   PHYSICAL_INTERACTION 882.0 0.88 STRING 36370105
MAPK1 MAPK3 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
ITGA1 ITGB1 â—¼   PHYSICAL_INTERACTION 887.0 0.88 STRING 36370105
PRKACA PRKAR2B â—¼   PHOSPHORYLATION ✅ + 0.88 0.88 Signor 15187164
PRKACB PRKAR2B â—¼   PHYSICAL_INTERACTION 888.0 0.88 STRING 36370105
YWHAZ BAD â—¼   PHYSICAL_INTERACTION ✅ 0.89 0.89 mint 1204662 8005727 11526496
VAPA EGFR â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 20029029 31980649 25754235 23956138
HSPA8 LRRK2 â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
PRKACG PRKAR1A â—¼   PHYSICAL_INTERACTION 889.0 0.89 STRING 36370105
DNAJB11 HSPA5 â—¼   PHYSICAL_INTERACTION 890.0 0.89 STRING 36370105
CDH2 JUP â—¼   PHYSICAL_INTERACTION 891.0 0.89 STRING 36370105
CDC25C PLK1 â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
AKAP5 PRKAR2A â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
AKAP3 PRKAR2A â—¼   PHYSICAL_INTERACTION 898.0 0.89 STRING 36370105
MAPK3 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19777442 10597268 12566304
MAPK1 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 8929531 10597268 12566304
EGFR CSK â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 24797263 31980649 24658140 25402006 16729043
YES1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 17145710 22430206 11160627
PIK3CB GRB2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 11002419 10995764 10448070
GRB2 TLN1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 12005431 9566877 7997267
PTK2B GRB2 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 10679059 12626562 9763606
HLA-C GRB2 â—¼   DOWN_REGULATES ✅ - 3.0 0.9 ACSN 11513144 21339333 9605119
FN1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18624398 19738201
PPP1CA MAPK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
MAPK3 PPP1CA â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 intact 211739200 12840032 8214413
MTOR GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PPP1R12A PLK1 â—¼   DEPHOSPHORYLATION ✅ 3.0 0.9 Reactome 18477460 22641346 22365832
PDPK1 XRCC6 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PRKACA PRKAA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19942859
YWHAZ GABARAPL2 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
CD247 SYK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 9295038 7761456 7522230
FN1 CSK â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 16040750 14754902 10446041
CREM CD247 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16237091
GNB1 GNAS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15782186 16189514 26186194
PPP1CA RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 7604263 16630891
FN1 ITGA4 â—¼   ENZYMATIC_REACTION ✅ 3.0 0.9 ACSN 20644254 22067905 24202395
PRKACA LRRK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 21390248 24351927
ILK CFL1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 18252715
PRKCZ MAPK7 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20538799 11158308
UBE2I CTBP1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 Reactome 20176810 20098713 12679040
CAMK2A PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 15845548
PRKCI LLGL2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12725730
ESR1 PRKACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 11457657 10949931 17068199
AKAP5 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 1512224 8599116 10939335
PRKACB PRKAR2A â—¼   PHYSICAL_INTERACTION 899.0 0.9 STRING 36370105
OGA GSK3B â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
GSK3B CAMSAP3 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
MAP4K5 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 16914735
CAMK2A LIPE â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 9636039
ESR1 SLC2A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23167795 16423895 19366879
VAPA VAPB â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 28514442 19515777 16227268 9920726 26496610 33961781 26186194 34079125
RPS6KA1 CFL1 â—¼   PHYSICAL_INTERACTION 3.0 0.9 intact 21900206 2001699 8089645
PPARA SLC2A4 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18037994 15665064 22100307
MAPK7 RPS6KA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 23331499 11544482 16626623
MAPK9 STMN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20630875
MAPK1 RPS6KA3 â—¼   PHYSICAL_INTERACTION 900.0 0.9 STRING 36370105
BAD YWHAZ â—¼   PHYSICAL_INTERACTION 901.0 0.9 STRING 36370105
PTK2 PXN â—¼   PHOSPHORYLATION ✅ + 0.9 0.9 Signor 15688067
PRKACB PRKAR1B â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
LRRK2 YWHAZ â—¼   PHYSICAL_INTERACTION 910.0 0.91 STRING 36370105
PRKACB PRKAR1A â—¼   PHYSICAL_INTERACTION 918.0 0.91 STRING 36370105
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
PXN PTK2 â—¼   PHYSICAL_INTERACTION ✅ 0.94 0.94 mint 25795725
AKAP5 PRKAR2B â—¼   PHYSICAL_INTERACTION 940.0 0.94 STRING 36370105
PTK2 PXN â—¼   PHYSICAL_INTERACTION 948.0 0.94 STRING 36370105
RPL36A RPS17 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
RPL36A RPL8 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
RPL36A RPL6 â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
CDC25C YWHAZ â—¼   PHYSICAL_INTERACTION 957.0 0.95 STRING 36370105
CDK2 CCNE1 â—¼   PHOSPHORYLATION ✅ - 0.96 0.96 Signor 19561641
YWHAZ RAF1 â—¼   PHYSICAL_INTERACTION ✅ 0.96 0.96 mint 14688280 309620200 8006563
PRKACA PRKAR1A â—¼   PHYSICAL_INTERACTION 968.0 0.96 STRING 36370105
EGFR GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19254954 7518560 31980649 9416834 7592693 23956138 14679214 10085134 7510700 27059931 21706016 25402006 16799092 16729043 8665853 15657067 24797263 12577067 8810325 7650032 11960376 23799367 25187647 8626525 10026169 19289468 18271526 21278786 7506413 17971399 8940013 20124286 11726515 9886492 10595738 24189400 9020117 19531499 20473329 9020193 8662998 8647858 1322798 8887653 10229072 16273093 25754235 31959764 11370743 16713569 21596750 9685397 24658140 31985874 22973453 11896612 20067773 17242169 19836242 8810340 21278788 30544639 7527043 9050991 11408594 8621459
PTK2B PXN â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
CAMK2A CAMK2D â—¼   PHYSICAL_INTERACTION 969.0 0.97 STRING 36370105
LLGL2 PRKCI â—¼   PHYSICAL_INTERACTION 971.0 0.97 STRING 36370105
PRKACA PRKAR1B â—¼   PHYSICAL_INTERACTION 972.0 0.97 STRING 36370105
GNAS GNB1 â—¼   PHYSICAL_INTERACTION 976.0 0.97 STRING 36370105
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
PRKACG PRKAR2B â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
GSK3B YWHAZ â—¼   PHYSICAL_INTERACTION 980.0 0.98 STRING 36370105
MAPK1 RPS6KA1 â—¼   PHYSICAL_INTERACTION 981.0 0.98 STRING 36370105
RAF1 YWHAZ â—¼   PHYSICAL_INTERACTION 984.0 0.98 STRING 36370105
CDK2 CCNE1 â—¼   PROTEIN_INTERACTION 0.99 0.99 HIPPIE 28514442 28137908 16431923 29439025 9891079 18559665 33854235 11940657 15004009 17431037 17361108 33854239 14681455 17254967 8867812 23853094 10827081 10330164 8662825 25852190 15557281 9192873 23455922 21092281 14536078 21372285 21241890 19631451 16223725 26496610 1388288 9716181 9472014 15980415 14701826 23602568 8978686 11433299 11132966 24771265 12839982 20587660 19470470 10359664 15514162 17970072 9840943 25728284 9660939 8647086 24358021 7799941 12529437 8756624 33961781 15670215 26186194 20837141 12800980
PRKAA2 PRKAG1 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PRKACA PRKAR2B â—¼   PHYSICAL_INTERACTION 993.0 0.99 STRING 36370105
RPL8 RPS17 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
RPL6 RPS17 â—¼   PHYSICAL_INTERACTION 995.0 0.99 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
GNB1 GNGT1 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
RPL6 RPL8 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
YWHAZ ARAF â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 19933840 20936779 25852190 20052757
RAF1 BAD â—¼   ENZYMATIC_REACTION ✅ 10.0 1.0 ACSN 11532940 12107820 12566895 14764585 15516985 19289794 19565474 24027568 8929532 9069260
RPS6KA3 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 11983683 15280015 10611223 12954615 9346240 23936765 11493700 10230394 10558990 8929531 9381178 17570479 19282669 10976111 11544290 17270021 10837486
PRKACB BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 15280015 10611223 12954615 9346240 10949026 11493700 10230394 10558990 8929531 9381178 17270021 10837486
PRKACG BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 17.0 1.0 Omnipath 15280015 10611223 10230396 12954615 9346240 10949026 11493700 10230394 10558990 8929531 9381178 17270021 10837486
PPP1CA BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 17145710 10811615 17274640 22820751
RAF1 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 38.0 1.0 Omnipath 11983683 12444011 10880354 19030972 19667065 22096607 15849194 16931767 17535812 16103085 9381178 23162742 12107820 18402774 12767520 10826997 8929532 8929531 12175651 25241761 19565474 10949026 19165420 9069260 21540285 17242355 23397142 19289794
RPS6KA1 BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 62.0 1.0 Omnipath 11983683 10880354 20166139 9346240 11493700 9381178 15037618 11152955 15280015 10230394 10558990 8929531 10976111 18669648 10837486 10611223 15226424 22558198 12954615 18246127 10521512 10949026 15972258 10679322 18039929 18707149 12897128 16403219 17270021
PRKACA BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 49.0 1.0 Omnipath 11983683 10880354 20166139 9346240 11493700 9381178 18794113 12931191 15280015 10230394 10558990 8929531 18669648 10837473 10837486 10611223 12954615 10949026 10851172 15123689 18707149 16403219 17270021
PRKCI BAD â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 21419810 15705582
CCNE1 CDK2 â—¼   PHYSICAL_INTERACTION 999.0 1.0 STRING 36370105
WEE1 CDK2 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 15279786 17303408 17660363 18590585 23508805 23897299 7575488
CDK2 MCM3 â—¼   ENZYMATIC_REACTION ✅ 18.0 1.0 ACSN 14536078 15147722 15175241 15279786 15677884 16581787 17038621 17102137 17116885 17296725 17303408 17582221 17660363 17713585 18590585 18636226 19793801 7575488
MAPK1 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10962581 12359725
WEE1 CDK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 58.0 1.0 Omnipath 17303408 24927813 25458954 19690332 16497976 18083107 30266203 15279786 15302935 15632290 12181445 17389395 17095507 7575488 19534553 7743995 18452278 12912980 22999936 21900495 24419005 1396589 18590585 10896159 18691976 15144186 20462953 12972555 16177568 17660363 17192257 11029659 34156324 17545210 19369195 26240362 19664994 11585773 25361894 20465818 17016520 15659558 18212344 13678583
CDK2 PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 12202491 17145710 14715909 17274640 16550609 18088087 17570479 9122166 97225924 15212693 10880350
CDK2 MCM3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 7575488 18590585 17296725 17303408 21965652 30062004 17102137 17116885 19793801 17582221 15232106 16189514 17660363 15279786
CDK2 CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20530684 28396830
CDK2 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 10428798 22431515 23390529 17570479 23770852
CDK2 PRKAR1A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 42.0 1.0 Omnipath 15572359 19007248 17081983 20166139 18767875 19562805 19413330 19415658 20068231 18452278 16582606 25605337 18669648 18691976 17287340 19651622 20058876 19664994 18707149 18212344
CDK2 CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 50.0 1.0 Omnipath 17145710 16223725 21092281 15004009 10962581 9840943 8643455 24358021 8861947 21372285 17570479 11237742 10330164 22558078 10652300 19561641 10477583 18691976 23853094 12144826 10500095 1388288 10827081 17970072 28137908 19470470 8756624 10809788 14536078 15364936
COL1A1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7716514 10464311 7688313
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
ESR1 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12894229 12421825 8200909 21705183
CAMK2A EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 17389395 17081983 3138233 20166139 10347170 15901825 16799092 18691976 8226933 20068231 1309762 7805884 92065884 1956339 7505275 18669648 15302935
MAPK1 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 12556561 1651322 17081983 3138233 15901825 1939237 91332050 2543683 2115882 17192257 1651323 15302935
MAPK3 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 22.0 1.0 Omnipath 1651322 17081983 3138233 15901825 16785992 1939237 91332050 27531070 17570479 2543683 2115882 34086370 17192257 1651323 15302935
PRKCB EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 16.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 7805884 17570479 12040186 19568798 15567848 14585353
PRKCD EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 11447289 8321321 11313945 12040186 15302935 6321473 1860884 6090944 19568798 14585353 17496910 21386996 2984676 11940581 85012702 19615955 2987962 12845332 3379075 15567848 16488589 17956904
PTK2B EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14963038 11274221 16713569 10777553
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 23331499 20809984 17284441 16713569 11887937
EGFR PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 23.0 1.0 Omnipath 16713569 16919435 25402006 10806474 29435030 20473329 7657702 19339212 17496910 15657067 24658140 19625610 7529872 20802513 31980649 10545505 24043698 15951569
SYK GRB2 â—¼   PHYSICAL_INTERACTION 9.0 1.0 Reactome 12456653 9341187 9705962 19372136 11071869 11449366 11909947 9697839 21822214
FGFR1 GRB2 â—¼   PHYSICAL_INTERACTION 10.0 1.0 Reactome 17505008 18757403 21666749 11689702 11739186 18381441 19809159 21160078 14534538 15448205
GRB2 SYK â—¼   PHYSICAL_INTERACTION 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
GRB2 KSR1 â—¼   PHYSICAL_INTERACTION 53.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11274345 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14724641 14764585 15169888 15173823 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9510155
GRB2 RAF1 â—¼   PHYSICAL_INTERACTION 54.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11034387 11062502 11385609 11447289 11532940 11777939 11907067 12040186 12175651 12419216 12479806 12566895 12640133 12782630 14585353 14764585 15169888 15516985 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17673906 18039929 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9069260 9510155
GRB2 SYK â—¼   SHARES_COMPLEX 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
GRB2 KSR1 â—¼   SHARES_COMPLEX 53.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11274345 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14724641 14764585 15169888 15173823 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9510155
GRB2 RAF1 â—¼   SHARES_COMPLEX 54.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11034387 11062502 11385609 11447289 11532940 11777939 11907067 12040186 12175651 12419216 12479806 12566895 12640133 12782630 14585353 14764585 15169888 15516985 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17673906 18039929 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9069260 9510155
CD247 GRB2 â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 7600293 8478617 8642247 9625766 9738502
GRB2 KSR1 â—¼   ENZYMATIC_REACTION ✅ 53.0 1.0 ACSN 10086337 10567412 10811803 10843677 10982827 11023813 11034387 11062502 11274345 11385609 11447289 11777939 11907067 12040186 12175651 12419216 12640133 12782630 14585353 14724641 14764585 15169888 15173823 15536084 15547943 15567848 15574420 15735649 15863030 16102570 16227978 16488589 16582911 16887996 17178906 17395718 17496910 17613518 17673906 19289794 19449109 19541618 19565474 19568798 19615955 21102635 22435554 24027568 26552706 7510700 8551221 8929532 9510155
GRB2 SYK â—¼   ENZYMATIC_REACTION ✅ 71.0 1.0 ACSN 10022831 10086337 10358164 10567412 10811803 10849428 10982827 11166270 11447289 11449354 11532940 11777939 11907067 11960372 12175651 12393695 12524384 12629515 12640133 13678960 14568985 15099563 15111329 15501236 15520864 15536084 15567848 15573129 15574420 16002046 16076871 16572188 16582911 16887996 17086423 17101731 17496910 17673906 17883421 19414323 19449109 19909365 20150200015 21149606 21372296 21378271 21910624 22064427 22461508 23390297 23609447 23896411 24217602 24346288 24670066 25922287 26201938 26552706 8189062 8226994 8551221 8837607 9000133 9157999 9295024 9314552 9396765 9570538 9632805 9753319 9763615
GRB2 ITGA4 â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
GRB2 ITGB1 â—¼   ENZYMATIC_REACTION ✅ 26.0 1.0 ACSN 10086337 10426994 10567412 10811803 10982827 11447289 11777939 11777960 11907067 12175651 12640133 15536084 15567848 15574420 16339513 16582911 16713974 16887996 17070508 17100878 17496910 17673906 18490724 19449109 26552706 8551221
PTK2B GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9560226 10329689 8695788 16713569 19380485 9091579 10749687 10354709
SYK GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11964172 16189514 22267732 10747947
GRB2 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 31.0 1.0 Omnipath 10806474 12558988 8649427 8816475 11119718 16298995 7597091 7997267 9148935 12110680 12005431 10085298 16713569 10749687 10354709 21900206
GRB2 KHDRBS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 20.0 1.0 Omnipath 10467411 20936779 21988832 7537265 9872323 8576157 11960376 11278465 9045636 21706016 16713569 12112020 7799925
IQGAP1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 15655247 11319218 8226933 1330321 1497021909368021 16135787 17563371 7992057 8248196
IQGAP1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 11319218 8226933 1330321 16135787 17563371 7992057 8248196
RAF1 MAPK1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
MAPK1 KSR1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
FGFR1 MAPK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
KSR1 MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 19219045 19541618 8226933 10567369 1330321 7992057 9858547 8248196
PRKCZ MAPK1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11035106 12942541 23109003 12900386 15721486
MAPK1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12975377 23602568 16424009 19058874 23397142 21707490
MAPK1 RPS6KA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 21988832 18156174 12016217 25241761 12832467 23602568 8939914 10480933 9915826 17906627 10980595 10856237 19282669
MAPK1 STMN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 26881937 20630875 22028470
MAPK1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16039586 28646232 18451303
MAPK1 RPS6KA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 60.0 1.0 Omnipath 17081983 32814053 20385094 11532940 7601337 23331499 15342917 8939914 21071413 23047924 20068231 11335727 9687510 12618428 18988627 18669648 23519423 23109003 18691976 12594221 9915826 17906627 8202512 9430688 19651622 12832467 11500364 14966081 29997244 25730857 8387505 10411321 18212344
MAPK1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 43.0 1.0 Omnipath 17081983 18767875 15849194 19690332 11409918 14654779 23331499 23180781 8226933 20068231 18988627 21917714 18669648 19541618 18691976 16407412 19933846 9922370 15664191 8388392 19651622 10801873 8349614 18775330 9604935
MAPK1 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 27342992 23405013
MAPK1 LIPE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11581251
MAPK1 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 10753946 15494312 11784715 14636584
MAPK1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 15655247 10949034 15528270 18372406 15461668 12118371 12466266 7495695 17615152 15059947 16076840 7491495 12093745 10409727 9528769 7838153
MAPK1 KHDRBS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 18691976 12478298 19664995 20068231
MAPK1 PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10187842
RAF1 MAPK3 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
MAPK3 KSR1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
FGFR1 MAPK3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 19652666 12419216 18452557 12974390
KSR1 MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 19219045 19541618 8226933 10567369 1330321 7992057 8248196
PRKCZ MAPK3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11035106 12942541 23109003 12900386 15721486
MAPK3 RPS6KA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 26.0 1.0 Omnipath 23331499 15342917 18039929 12832467 23109003 8387505 14966081 9915826 21071413 17906627 9430688 11335727 18988627 11532940 10411321
MAPK3 RPS6KA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 18156174 25241761 12832467 8939914 9915826 17906627 10980595 10856237 19282669
MAPK3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10949034 18372406 15461668 9528769 12118371 14680484 17615152 15059947 16076840 7491495 12093745 15212693 15528270 7838153
MAPK3 FGFR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 27342992 23405013 18411303
MAPK3 PPARA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 10187842
MAPK3 STMN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 72.0 1.0 Omnipath 17081983 18767875 9731215 20230923 17693683 11135364 19413330 8314790 19664995 19415658 16083285 20068231 18452278 9712920 30628717 94064639 1737801 18491316 18669648 8144611 8245003 26505358 17287340 16094384 19033656 19651622 20058876 8376365 8325880 17924679 19162178 19664994 18707149 25692552 8125092 16964243 18212344
MAPK3 LIPE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 11581251
MAPK3 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 16039586 28646232
MAPK3 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 14654779 23331499 19541618 18691976 16407412 19933846 9446616 9922370 15664191 18988627
PTP4A3 MTOR â—¼   ENZYMATIC_REACTION ✅ 13.0 1.0 ACSN 17409395 19440036 19945467 20609352 21084277 23691193 24030100 24376839 24696260 25136802 26597054 27328425 27572739
NUAK1 PPP1R12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17739896 24171924 22516431 18088087 19367720 19690332 20354225 19413330 18669648 29106388
NUAK1 LATS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 19369195 18691976 19927127 19690332 19413330 18669648
PLK1 CDC25C â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11073952 17596790 18931676 19270156 19622404 19686080 8127874
PLK1 WEE1 â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 ACSN 11073952 17596790 18931676 19270156 19622404 19686080 8127874
PLK1 WEE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 28.0 1.0 Omnipath 17145710 18931676 16085715 15350223 18285803 19270156 26899266 19489726 19622404 28415805 30067982 23051732 19686080 15070733
PLK1 CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 39.0 1.0 Omnipath 14968113 19622404 11202906 10980711 20668692 19597481 19686080 19270156 12595692 16189514 19503101 17634129 19607708 14532005 24525428 27038604 22852086 16753148 17596790 28396830 17307877 11897663 18931676
PDPK1 PRKCD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 37.0 1.0 Omnipath 16505477 21310943 11839738 31511386 9748166 25472878 25755284 15811957 15133032 11781095 19664995 15024053 15302935 15949469 14581488 28784722 17570831 18669648 11381116 20058876 17965192 19632318 20501830
PRKCD G6PD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20649491
PRKCD YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 9705322 12861023
SSRP1 ESR1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 15171726 23810005 1406642 19946334
CSK TLN1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 14754902 8755247 11940607 17218263 18434644 10964917 10446041
TLN1 PXN â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 10591186 11592085 12413632 12616499 14662834 15356110 1673988 19454690 19965656 20231889 2150484 23364881 23886063 24343663 24440149 25384214 7512027 9712030 9738502
PTK2 TLN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 9442086 7622520 15688067
PXN TLN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 7534286 8641358 9054445
TLN1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 19118207 12606711 7716514 3124107 10497223 19118212 21947080 11279249
PRKAG1 PRKAA2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 20562859 10698692 26186194 9224708 17012231 16054041 25416956 31515488 32296183
PRKAA2 ACACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 35.0 1.0 Omnipath 19651622 11052978 20166139 9029219 18669648 18767875 2900138 12015362 20068231 18707149 19061860 17519230 7907095 7915280 29899443 16326698 18212344
GNGT1 GNB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 8.0 1.0 Omnipath 25675501 8636150 9789084 10360181 12782285 19168127
CSK YES1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 11489946 16537894 19369195 18691976 7690925 12640114 15592455 18083107 14967142 16439366
YES1 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11369622 12558988 16293639 12590707 25868388 15728464 25416956 32296183 10753828 23397142
YES1 CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 18479465
CD247 SYK â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 8226994 18818202 8862523 8340414 7522622 7530449 9314552
CD247 SYK â—¼   ENZYMATIC_REACTION ✅ 21.0 1.0 ACSN 10358164 10562324 11353765 11449354 12393695 12731048 15081523 15099567 18768831 20814939 21059766 2139103 23414611 24445665 7523143 8344348 8478617 8551221 9603467 9625766 9738502
SYK PTK2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 9560226 8816475 9988732 15105428 9727056 10747947 14624447
SYK PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9169439 9342235 16189514
PTP4A3 ITGB1 â—¼   PHYSICAL_INTERACTION 15.0 1.0 ACSN 16472776 19161977 19454690 19487819 19930715 22470492 23092334 23691193 24376839 27588115 28284838 9003039 9456329 9763606 9973479
ITGB1 ITGA4 â—¼   PHYSICAL_INTERACTION 9.0 1.0 ACSN 12626562 19161977 19454690 19487819 22470492 9003039 9456329 9763606 9973479
ITGB1 FN1 â—¼   PHYSICAL_INTERACTION 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
PTP4A3 ITGB1 â—¼   PROTEIN_INTERACTION 15.0 1.0 ACSN 16472776 19161977 19454690 19487819 19930715 22470492 23092334 23691193 24376839 27588115 28284838 9003039 9456329 9763606 9973479
ITGB1 ITGA4 â—¼   PROTEIN_INTERACTION 9.0 1.0 ACSN 12626562 19161977 19454690 19487819 22470492 9003039 9456329 9763606 9973479
ITGB1 FN1 â—¼   SHARES_COMPLEX 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
PTP4A3 ITGB1 â—¼   ENZYMATIC_REACTION ✅ 15.0 1.0 ACSN 16472776 19161977 19454690 19487819 19930715 22470492 23092334 23691193 24376839 27588115 28284838 9003039 9456329 9763606 9973479
ITGB1 PTK2B â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 12626562 19161977 19454690 19487819 22470492 9003039 9456329 9763606 9973479
ITGB1 PTK2 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
ITGB1 CFL1 â—¼   ENZYMATIC_REACTION ✅ 25.0 1.0 ACSN 10461188 10545505 10559936 10613909 11340065 11413130 11950587 15866889 16919435 17522712 18037882 19161977 19339212 19454690 19487819 22067905 22154077 22470492 24202395 7529872 7657702 9003039 9456329 9763606 9973479
ITGB1 FN1 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
FN1 ITGB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 27.0 1.0 Omnipath 9842903 22451694 17015452 18480047 19738201 7688313 1694173 6325925 25237190 26456826 10772816 7626807 21985969 6284125 1532572 11010812 8120056
ITGB1 PTK2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9022036 9366396 15695828
ITGB1 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 8649427 21909923 8878413 10545505 7657702 9003039 19339212 19487819 19161977 16189514 16919435 7529872 19889638
ITGB1 ILK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 18339839 9736715 8538749 16189514 11402068
PRKACA CSK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 9224730 11181701 20826718 31125786 12600271
CSK PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 18823558 21829547 9890993 27803182 21062671 7529872 21709741
CSK PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 18.0 1.0 Omnipath 17389395 18707149 27447856 11695992 7529872 9890993 14665621
CD247 PXN â—¼   ENZYMATIC_REACTION ✅ 24.0 1.0 ACSN 10562324 10925299 11353765 11438547 11875494 12415267 12731048 12811837 15735648 16713974 17371980 20435894 20814939 21059766 23414611 23508573 23620508 23886063 24378531 7600293 8478617 8642247 9625766 9738502
PTP4A3 PXN â—¼   DOWN_REGULATES ✅ - 4.0 1.0 ACSN 17409395 23691193 24376839 27588115
PTK6 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17081983 15572663 15592455 18676874 18083107 7537852 17389395 7493940 7615549 19534553 11774284 15107421 12408869 10823820 16254239 15817476 16094384 19304789 16212419 21423176 15951569
PTK2 PXN â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 16298995 26053221 15688067 15572663 15592455 7963537 17389395 25405379 26546726 9658172 15107421 22581436 10823820 16254239 25226367 15817476 10330411 9756887 19543320 9054445 10545505 18707149 29127427 15494312 10764815 7537852 9442086 33823745 12408869 20419088 20655620 22270917 18669648 28373581 10455189 16094384 23936270 19138410 22638989 11337490 11514617 27402964 16713569 7615549 10931187 11774284 26700725 27708220 20068231 20473365 28928239 7561682 34475475 28427224 28068967 8922390 24885567 23209645 27669437 15212693 26711338 9422762 11304546 28214467 26697169 12065577 28415719 10753828 11919182 24364863 9230116 11113628 21741599 10417825 15252114 24642576 22044652 21034468
PXN ILK â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 10.0 1.0 Omnipath 11694518 11304546 10592173 16936772 17553790
RAF1 KSR1 â—¼   PHYSICAL_INTERACTION 7.0 1.0 Reactome 25435214 20179705 20141835 16364920 20130576 15035987 25907612
PRKACA RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 53.0 1.0 Omnipath 19007248 11971957 20166139 18767875 20230923 9001246 10576742 23331499 20068231 7935389 18669648 18691976 9922370 15664191 19651622 12801936 9091312 10862777 9710607 11997508
KSR1 RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 33.0 1.0 Omnipath 7477354 12932319 9665134 9094715 19766101 23331499 8601312 19595761 11478855 8332195 15520859 8503013 16093354 19541618 19933846 10205168 7760835 18775988 18789263 11134016 8180183 1990291
YWHAZ RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 46.0 1.0 Omnipath 17145710 7939632 7935795 16306228 9153224 20052757 8085158 8601312 16041367 7628630 11697890 9632690 25852190 9261098 16093354 12861023 15664191 22222486 19049963 10620507 17979178 10611249 14688280 10887173 20679480 12360521
PRKCB RAF1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 8288587 1386920 12917261 22826029
RAF1 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 46.0 1.0 Omnipath 17145710 7939632 7935795 16306228 9153224 20052757 8085158 8601312 16041367 7628630 11697890 9632690 25852190 9261098 16093354 12861023 15664191 22222486 19049963 10620507 17979178 10611249 14688280 10887173 20679480 12360521
ITGA4 PTK2B â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 12626562 19161977 19454690 19487819 22470492 9003039 9456329 9763606 9973479
ITGA4 PTK2 â—¼   ENZYMATIC_REACTION ✅ 9.0 1.0 ACSN 12626562 19161977 19454690 19487819 22470492 9003039 9456329 9763606 9973479
PRKACA ITGA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 21224395 20166139 18578522 23979717 31562188 18583710 18707149 17603879 19401330 12837751 11533025
FN1 ITGA4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9117345 9842903 19738201 11010812
UBE2M CUL3 â—¼   PHYSICAL_INTERACTION 12.0 1.0 Reactome 19617556 18826954 25349211 23912815 25314029 18206966 21940857 23201271 26906416 19250909 30610225 25531226
PPP1R12A ROCK1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 9354661 8662509 11331307 11942626
ROCK1 PPP1R12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 52.0 1.0 Omnipath 11384979 15723050 18767875 19607793 19701943 9354661 10926869 18077418 18669648 10579722 15826939 12220642 26701920 17525332 19997641 12600888 11931630 11719507 15814590 8662509 12563012 12919947 10601309 18212344 12359219
ROCK1 PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 9182576 22348083 16254240 15247219 16760434 10744763 17745990 7529876 12960434
PDPK1 PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 12887331 14500673 11222751 18691976 10075713 20332120 9768361 9748166 17335005 10357815 16189514 11141077 16051884 11781095 10764742 14604996
PDPK1 PRKCB â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 15209375 17115692 9889098 16189514 11376011
PDPK1 RPS6KA3 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 25241761 10480933 17906627 19956600 10856237 28314444
PDPK1 PRKCI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10764742 16189514 27554858
PDPK1 PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 17.0 1.0 Omnipath 16026785 20732331 15481030 22493239 10698939 9707564 8706898 20137943 21774789 17192257 22154087 20481595 12372837 16765046
PDPK1 RPS6KA1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 19.0 1.0 Omnipath 20058876 18767875 10480933 7642538 17906627 27028868 9430688
ILK PPP1R12A â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 34.0 1.0 Omnipath 15826939 11931630 11384979 12030846 18669648 18767875 12220642 18077418 12563012 25168281 12919947 10601309 24356468 12600888 18212344
ILK GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 18.0 1.0 Omnipath 15207235 14990992 16799642 20827300 27683053 9736715 12960424 26547035 17490631 12629168 17182785 21035499 16189514 17107957 16936772 17485554
PTK6 KHDRBS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 14.0 1.0 Omnipath 23331499 10913193 19304789 16179349
GSK3B CDK4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 11152665 20537194 10385618 11124803 12969793 19757160 16732330 10486203 16039586 14536078 18167338 12459251 12615961
WEE1 CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 7575488 18590585 17303408 18319725 17660363 15279786
PRKCZ GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 18353303 14657655 11481324
FN1 PTK2 â—¼   ENZYMATIC_REACTION ✅ 14.0 1.0 ACSN 12731048 18037882 19161977 19454690 19487819 20644254 20814939 22067905 22470492 24202395 9003039 9456329 9763606 9973479
CREB1 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 2170405 22357921 8648265 15908479 1845987 8803927 2542772 15608673 1404598 1320003 12372774
JAK3 PTK2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21071413 23331499 9512511
PTK2B PTK2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 11.0 1.0 Omnipath 9182576 16254240 15247219 16760434 7529876 12960434
PTK2B GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 26274564 10601262 16452634 24931005
CREB1 PRKACA â—¼   ENZYMATIC_REACTION ✅ 7.0 1.0 Reactome 19244110 12150772 12082174 2573431 9733829 17908236 15879576
CREB1 RPS6KA1 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 11160957 11698596 12842905 9770464
CREB1 RPS6KA3 â—¼   ENZYMATIC_REACTION ✅ 4.0 1.0 Reactome 11160957 11698596 12842905 9770464
CAMK2D CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11175347 12356771 15733869 22554507 8887554 9528766 11018520 11698596 11160957 11969286 12235136 7958915 9829964 9687510 11909979 8688081
GSK3B CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 8.0 1.0 Omnipath 16568235 12162494
RPS6KA1 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 17145710 11175347 12356771 15733869 11160957 11544482 15138267 11532940 9829964 7958915 10558990 12235136 11335727 9687510 8887554 11698596 8688081 9528766 11018520 11969286 11909979
RPS6KA3 CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 11175347 12356771 15733869 8887554 9528766 9770464 9829964 11018520 11160957 11698596 11969286 12235136 17570479 7958915 9687510 1545823 11909979 8688081
PRKACA CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 22.0 1.0 Omnipath 11175347 12356771 15733869 11160957 21902831 2885756 2875459 7958915 9829964 12235136 12763014 9687510 8887554 15568017 11698596 8688081 9528766 11018520 11969286 11909979 8336722
CAMK2A CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 26.0 1.0 Omnipath 11175347 12356771 15733869 1646483 11160957 9668047 7958915 9829964 12235136 11970864 9687510 8887554 11698596 8688081 9528766 11018520 11969286 11013247 11909979
CREM CREB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 22531917 16189514 7809053 1847666
PPP1CA CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 9543386 14592972 11897663 16467385
MAPK9 CDC25C â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 12742231 20220133 16964243 8119945
PRKAR1A PRKACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 17145710 15655353 17353931 26687711 11834733 24855271 32296183 24700472 9405392 25477193
PRKACA LIPE â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 17785468 14641008 19018281 9636039 9417067 11581251
PRKACA KDELR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14517323
PRKACA PPP2R5D â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 9688562 17110335 17301223 29294329
PRKACA ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 9.0 1.0 Omnipath 22266331 9891036 15193262
PRKACA PRKAR2B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 27107012 15187164 32296183 17148597 21795691 33608270 25477193
PRKACA GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 20.0 1.0 Omnipath 16543730 15845746 18691976 19836308 8524413 12054501 16039586 12147701 16522636 11035810 18669648
PRKACA STMN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 49.0 1.0 Omnipath 7925472 17081983 18767875 17693683 19413330 19664995 19415658 17001604 20068231 18452278 94064639 18669648 8245003 17287340 10913145 19651622 11415983 8376365 8002936 17924679 19664994 8125092 16964243 18212344
PRKACA SPTBN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 13.0 1.0 Omnipath 9798950 20166139 20068231 18669648 17088250
PRKACA PPP1R1B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 15.0 1.0 Omnipath 11717349 1494946 10604473 15726118 15536496 6319628 6296685 3339428 17194217
PRKACA NOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 12630910 10400690 1375933 7532810 10874031
PRKACA YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 11.0 1.0 Omnipath 29109150 11956222 12861023 16376338 19451227
PRKACA ACACA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 6.0 1.0 Omnipath 7907095 2900138
RPS6KA1 GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 16.0 1.0 Omnipath 11584304 11583116 23331499 8250835 7980435 8524413 24931005 19346560 12054501 16039586 12147701 11035810 22615844 16543730
PPP2R5D GSK3B â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 19131971 10026142 10995457 18042541 18559511 16680151
GSK3B AKAP11 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 26088133 12147701 23602568
GSK3B CCNE1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 38.0 1.0 Omnipath 16944320 11967263 14663202 8524413 8861947 16039586 17570479 14536078 12615961 19561641 15465828 25241761 18691976 18319725 12459251 15020233 20537194 11124803 16131838 9832503 15364936
GSK3B ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 21.0 1.0 Omnipath 10428798 10949034 17609434 15461668 9528769 12118371 15059947 16076840 17570479 7491495 12093745 8308015 15212693 15528270 7838153
CAMK2A STMN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 27.0 1.0 Omnipath 7925472 26317901 16554300 14645234 26087399 20110360 11015208 27130664 31546234 11058583 8245003 16982419 27041561 30786936 10913145 9271428 7775478 8125092 9686569 19359244 30320402 21768358
CAMK2A NOS1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 19.0 1.0 Omnipath 12630910 10400690 1375933 10874031
MLXIPL ACACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 17716660 21453770 20139635 20100709 15496471
ESR1 HSPB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 15833836 10960840 11174852 8923463
RPS6KA3 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 24.0 1.0 Omnipath 11139588 23936765 17570479 19925796 11432835 11507039 19112174 9528769 7838153
RPS6KA1 ESR1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 36.0 1.0 Omnipath 10949034 15528270 19925796 15461668 25336146 11139588 12118371 30034315 15059947 16076840 7491495 12093745 11432835 10411321 11507039 9528769 7838153
VAPA CERT1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18165232 14685229 16895911 16571669
PPP1R1B PPP1CA â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 11440854 9108011 19651774 10604473
PRKCB STMN1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 21.0 1.0 Omnipath 8245003 7637391 17081983 8376365 8325880 16427064 9731215 16083285 93315482 8125092 8325881 16094384 11135364 94064639 16964243 15212693 9271428
PRKCB STXBP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 8631738 12519779 12950453
VAPB CERT1 â—¼   PHYSICAL_INTERACTION 4.0 1.0 Reactome 18165232 14685229 16895911 16571669
TULP3 GPR161 â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 23332756 20889716 19223390 19286674 24845016
MAPK9 YWHAZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 17570479 15071501