Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
GRB2 DUT â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
TP53 DUT â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 19015155 12096336
TP53 EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
GRB2 HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5216105 12577067
GRB2 EHMT2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 17474147 8109998
PLK1 TP53 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 7266226 19833129
PLK1 G6PD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 29138396
PRKCD CAT â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 24211614
PRKCD CYBA â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19948736
TP53 HSPB1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 16169070 5217955
TP53 CTSD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 11865007 10029407
TP53 CHKA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9501176 10094833
TP53 CAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 15059885 18487368
TP53 FN1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 15230856 8732672
TP53 PRKCG â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 10614633 9895308
PAK4 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 27496712
TP53 CTSD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18431400
COX5B COX4I2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17418790 8194600
COX5B COX4I2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17418790 8194600
HSPB1 CYCS â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 10980706
COX5A COX4I2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 ACSN 17418790 8194600
COX5A COX4I2 â—¼   SHARES_COMPLEX 2.0 0.8 ACSN 17418790 8194600
NFE2L2 CBR3 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 20806931 22001310
NFE2L2 CPOX â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9092564 23871830
NFE2L2 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 23637463 22547061
SH2D3C CAV1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20808760 1000457
AKT1 ACOT4 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 33148467
EZH2 BMI1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 2.0 0.8 Omnipath 21465172 19351856
AKT3 BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 22505453
FGFR3 DPYS â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
DBT BCKDHA â—¼   PHYSICAL_INTERACTION 2.0 0.8 Reactome 2188967 10745006
PRKCE ALDH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 28056995
SREBF1 G6PD â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 12177166 19062325
SREBF1 FDPS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 8798690 9651391
SREBF1 CYP17A1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 16306078 23610160
DBH ALDH1A1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 108050 32814053
AKT3 AKT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
CHIT1 VHL â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
EZH2 EHMT2 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 27634302 26496610
ACOT2 ACOT1 â—¼   PROTEIN_INTERACTION 0.82 0.82 HIPPIE 28514442 33961781
ENPP6 ALG9 â—¼   PROTEIN_INTERACTION 0.83 0.83 HIPPIE 28514442 33961781 26186194
ATP6AP1 ATP6V0A2 â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
CYC1 CYCS â—¼   PHYSICAL_INTERACTION 838.0 0.83 STRING 36370105
GRB2 HSPB1 â—¼   PROTEIN_INTERACTION 0.84 0.84 HIPPIE 31980649 12577067
HSPB1 TP53 â—¼   PHYSICAL_INTERACTION 848.0 0.84 STRING 36370105
FGFR3 GRB2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 9045692 26344197
HSPB1 G6PD â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 21157431 26344197
ATP6V0A2 ATP6V1F â—¼   PHYSICAL_INTERACTION 859.0 0.86 STRING 36370105
SOX2 EHMT2 â—¼   PROTEIN_INTERACTION 0.86 0.86 HIPPIE 35140242 23667531
ATP6AP1 ATP6V1C1 â—¼   PHYSICAL_INTERACTION 862.0 0.86 STRING 36370105
FN1 VHL â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
EGFR HSPB1 â—¼   PROTEIN_INTERACTION 0.88 0.88 HIPPIE 24189400 23397142 15657067
CAV1 EGFR â—¼   PHYSICAL_INTERACTION 881.0 0.88 STRING 36370105
COX4I2 CYCS â—¼   PHYSICAL_INTERACTION 885.0 0.88 STRING 36370105
EGFR AKT1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 24658140 25402006 31980649
AKT1 HSPB1 â—¼   PROTEIN_INTERACTION 0.89 0.89 HIPPIE 17510053 31980649 12740362 11042204 23397142
EGFR HDAC6 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 20029029 31980649 24658140 20133936 25402006
EGFR CAV1 â—¼   PROTEIN_INTERACTION 0.9 0.9 HIPPIE 16407214 19446582 22411794 31980649 12388423 24658140 15273741 25402006 16799092 9374534 34079125 12354760 10781609 15657067
FN1 GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 18624398 19738201
EZH2 TP53 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 20132185 21546904 24006445
NFE2L2 CAT â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 22493435
AKT3 HSPB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 19593530
SREBF2 ACLY â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 10777536 10801800
SREBF2 FDPS â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 12177166 20450493
EGFR GRB2 â—¼   PHOSPHORYLATION 0.92 0.92 Signor 11726515
ATP6AP1 ATP6V0A1 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0A1 ATP6V1F â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0A1 ATP6V1C1 â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6AP1 ATP6V1F â—¼   PHYSICAL_INTERACTION 922.0 0.92 STRING 36370105
ATP6V0A1 ATP6V1G2 â—¼   PHYSICAL_INTERACTION 931.0 0.93 STRING 36370105
ACO2 FH â—¼   PHYSICAL_INTERACTION 932.0 0.93 STRING 36370105
COX5B CYC1 â—¼   PHYSICAL_INTERACTION 935.0 0.93 STRING 36370105
ATP6V1C1 ATP6V1F â—¼   PHYSICAL_INTERACTION 941.0 0.94 STRING 36370105
COX5B COX6A1 â—¼   PHYSICAL_INTERACTION 945.0 0.94 STRING 36370105
COX5A COX6A1 â—¼   PHYSICAL_INTERACTION 946.0 0.94 STRING 36370105
EGFR GRB2 â—¼   PROTEIN_INTERACTION 0.97 0.97 HIPPIE 19254954 7518560 31980649 9416834 7592693 23956138 14679214 10085134 7510700 27059931 21706016 25402006 16799092 16729043 8665853 15657067 24797263 12577067 8810325 7650032 11960376 23799367 25187647 8626525 10026169 19289468 18271526 21278786 7506413 17971399 8940013 20124286 11726515 9886492 10595738 24189400 9020117 19531499 20473329 9020193 8662998 8647858 1322798 8887653 10229072 16273093 25754235 31959764 11370743 16713569 21596750 9685397 24658140 31985874 22973453 11896612 20067773 17242169 19836242 8810340 21278788 30544639 7527043 9050991 11408594 8621459
GRB2 EGFR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 16729043 5218694
ATP6V1F ATP6V1H â—¼   PHYSICAL_INTERACTION 983.0 0.98 STRING 36370105
COX5A CYC1 â—¼   PHYSICAL_INTERACTION 990.0 0.99 STRING 36370105
EGFR GRB2 â—¼   PHYSICAL_INTERACTION 998.0 0.99 STRING 36370105
EGFR GRB2 â—¼   ENZYMATIC_REACTION ✅ 5.0 1.0 ACSN 10404636 20430953 23010081 25987127 28513565
CAV1 EGFR â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 11102446 17517963 18458534 19411448 20855962 21051947 21150282 21729786 22411312 22874531 23907124 25364523 26828520
TP53 EGFR â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 13.0 1.0 Omnipath 20190820 18359760 9664135 10029407 8152794 11713584 8887630 9285564 19597475 11546792 1586628 18604200 18391986
CAMK2G EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 3138233 10347170 16799092 1309762 7805884 7505275 92065884 15302935
PRKCE EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 33.0 1.0 Omnipath 11447289 21749319 8321321 11313945 12359306 25402006 12040186 23830194 6321473 1860884 27016036 6090944 19568798 14585353 17496910 21386996 17942932 20692258 24658140 1556153 2984676 18042729 11940581 11185568 19615955 2987962 23205726 12845332 10816576 3379075 15567848 16488589 16793002
PRKCD EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 30.0 1.0 Omnipath 11447289 8321321 11313945 12040186 15302935 6321473 1860884 6090944 19568798 14585353 17496910 21386996 2984676 11940581 85012702 19615955 2987962 12845332 3379075 15567848 16488589 17956904
PRKCG EGFR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 14.0 1.0 Omnipath 17496910 11940581 21386996 11447289 19615955 16488589 6321473 8321321 12845332 11313945 12040186 19568798 15567848 14585353
EGFR GRB2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 109.0 1.0 Omnipath 9544989 10595738 23956138 27059931 10026169 16273093 11726515 24697349 21596750 19289468 7518560 21706016 23799367 9050991 16317285 16713569 25402006 11370743 24797263 8647858 8887653 9416834 21278786 16799092 8662998 10229072 11896612 7592693 19509291 8810325 24189400 19836242 11960376 7506413 18271526 15657067 10085134 24658140 17242169 7510700 8940013 7650032 8810340 11084343 12577067 7527043 31980649 11408594 19531499 20124286 23178716 9886492 23181695 9020117 8479540 14679214 12648464 1322798 17991782 16729043 17971399
EGFR HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 15.0 1.0 Omnipath 20133936 31980649 22896792 20029029 24658140 21151618 25402006 23084749
EGFR CAV1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 30.0 1.0 Omnipath 17145710 31980649 22411794 9374534 19446582 16799092 12388423 15657067 24658140 19625610 16407214 18789131 25402006 15951569 10781609 16332692
PAK4 FH â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 30683654
TP53 PLK1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 17172872 17981789 15024021 22405092 20962589 24076372 23948487 15016801 22184120 19713933 16369493 23474762
PLK1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 10.0 1.0 Omnipath 22653443 19833129 16753148 23948487
PRKCD G6PD â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 20649491
PRKCD TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 17906639 16314418 16377624
PRKCD NFE2L2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 12.0 1.0 Omnipath 23434765 19920073 12198130 22078747 29710809 28638475 28819452 23275004
TP53 CAV1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10684646 20610713 17014845 11076533
TP53 AKT1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ - 4.0 1.0 Omnipath 12485897 18661553 19763735
HSPB1 TP53 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 25241761 16169070 16713569 17184779
VCP NFE2L2 â—¼   PHYSICAL_INTERACTION 6.0 1.0 Reactome 33444648 11733065 28115426 15652483 10811609 29153394
AKT1 VCP â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 16551632 19335618 16027165
COX5A COX5B â—¼   PHYSICAL_INTERACTION 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
COX5A COX5B â—¼   SHARES_COMPLEX 6.0 1.0 ACSN 11389896 15119951 16051147 17418790 19625251 8194600
AKT1 BMI1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 22505453 23092893
AKT1 HSPB1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 9.0 1.0 Omnipath 12740362 11042204 19593530 22983196 17510053 23397142
AKT1 EZH2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 12.0 1.0 Omnipath 22391560 24526064 29864144 34230470 16224021 26517694
EHMT2 DNMT3A â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 19308066
SREBF1 ACACA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 12871210 23300015 20139635 11994399 22279139 11907029
SREBF1 ACLY â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 10777536 11994399 10801800
SREBF1 SREBF2 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 4.0 1.0 Omnipath 14702347 16282353 9786926 11278785