Protein list:

Seperate proteins by space | Example

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Protein:

Eg: PBRM1 | ARID1A | BRCA1
Function:

Eg: Homologous recombination
Path:


Eg: SMC5 > DMC1 | PBRM1 > BRCA2
Relationship:

Full list of relationships
Graph tools:

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Filter Table:
SourceTargetRelationship TypeDirectedSignDB ScorePKG ScoreDatabaseReferences
ESR2 NOTCH2NLA â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 19376833
BRD7 H3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 12489984 6546635
GTF3C4 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 18022353
CDK7 TBP â—¼   PHYSICAL_INTERACTION 800.0 0.8 STRING 36370105
TCF4 DOT1L â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1000539 21103407
DOT1L TCF4 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 1000539 21103407
TCF4 EP300 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5219834 17410209
MTOR GTF3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20543138 1005188107
RPTOR GTF3C2 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20543138 1005188107
GTF3C2 MTOR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20543138 1005188107
GTF3C2 RPTOR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20543138 1005188107
GTF3C5 MTOR â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 20543138 1005188107
MTOR PDPK1 â—¼   PHYSICAL_INTERACTION 2.0 0.8 intact 5214238 11438723
PDPK1 PRKCZ â—¼   ENZYMATIC_REACTION ✅ 2.0 0.8 Reactome 12840507 9889098
PLK1 TP53BP1 â—¼   PHOSPHORYLATION ✅ 2.0 0.8 intact 1000287 20126263
TBP SUB1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 2.0 0.8 Omnipath 9512709 9792714
BRF1 GTF3C3 â—¼   PHYSICAL_INTERACTION 801.0 0.8 STRING 36370105
GTF3C5 PBRM1 â—¼   PHYSICAL_INTERACTION 810.0 0.81 STRING 36370105
LRRK2 PCNA â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 31046837 24725412
HDAC6 EP300 â—¼   PHYSICAL_INTERACTION 0.82 0.82 HIPPIE 15102857 19344692 12718889 22778253 23133622
GTF3C2 GTF3C6 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
GTF3C3 GTF3C6 â—¼   PHYSICAL_INTERACTION 824.0 0.82 STRING 36370105
ESR2 EP300 â—¼   PHYSICAL_INTERACTION 0.83 0.83 HIPPIE 18765668 11500849
EP300 PCNA â—¼   PHYSICAL_INTERACTION 831.0 0.83 STRING 36370105
BRD7 GTF3C5 â—¼   PHYSICAL_INTERACTION 835.0 0.83 STRING 36370105
CUL1 CUL3 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
TOP1 TP53BP1 â—¼   PHYSICAL_INTERACTION 840.0 0.84 STRING 36370105
PRKCZ PRKCI â—¼   PHYSICAL_INTERACTION ✅ 0.85 0.85 mint 24375676
CUL3 CUL1 â—¼   PHYSICAL_INTERACTION 0.86 0.86 HIPPIE 26344197 21145461
GTF3C1 GTF3C3 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
GTF3C2 GTF3C3 â—¼   PHYSICAL_INTERACTION 870.0 0.87 STRING 36370105
GTF3C2 GTF3C5 â—¼   PHYSICAL_INTERACTION 871.0 0.87 STRING 36370105
BRD7 PBRM1 â—¼   PHYSICAL_INTERACTION 872.0 0.87 STRING 36370105
GTF3C1 GTF3C5 â—¼   PHYSICAL_INTERACTION 873.0 0.87 STRING 36370105
GTF3C2 GTF3C4 â—¼   PHYSICAL_INTERACTION 876.0 0.87 STRING 36370105
PCNA TP53BP1 â—¼   PHYSICAL_INTERACTION 877.0 0.87 STRING 36370105
GTF3C1 GTF3C3 â—¼   CORRELATES + 0.88 0.88 CCLE 31978347
TBP BRF1 â—¼   TRANSCRIPTIONAL_REGULATION ✅ + 3.0 0.9 Omnipath 21106530 18700021 9155032
EP300 HDAC6 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 3.0 0.9 Omnipath 15102857 19344692
BDP1 BRF1 â—¼   PHYSICAL_INTERACTION 930.0 0.93 STRING 36370105
MDC1 TP53BP1 â—¼   PHYSICAL_INTERACTION 951.0 0.95 STRING 36370105
BDP1 TBP â—¼   PHYSICAL_INTERACTION 952.0 0.95 STRING 36370105
PCNA TOP1 â—¼   PHYSICAL_INTERACTION 955.0 0.95 STRING 36370105
PCNA SPRTN â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
BRF1 TBP â—¼   PHYSICAL_INTERACTION 973.0 0.97 STRING 36370105
RPTOR MTOR â—¼   PHYSICAL_INTERACTION ✅ 0.98 0.98 mint 24036451
MTOR RPTOR â—¼   COLOCALIZATION ✅ 0.98 0.98 mint 21045808 8088164
MTOR RPTOR â—¼   PHOSPHORYLATION ✅ + 0.98 0.98 Signor 19346248
GTF3C3 GTF3C5 â—¼   PHYSICAL_INTERACTION 992.0 0.99 STRING 36370105
PCNA EP300 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 7.0 1.0 Omnipath 18263614 11268218 16713569
CUL1 MTOR â—¼   ENZYMATIC_REACTION ✅ 19.0 1.0 ACSN 11900249 12648680 12820959 14536078 15071497 15147722 15340381 15459660 15688063 15703371 16697054 17884153 18636226 18787170 18931676 19622404 19686080 19809470 19847258
H3C2 DNMT3L â—¼   PHYSICAL_INTERACTION 5.0 1.0 Reactome 19834512 21979949 16829525 15861382 17687327
DOT1L H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 5.0 1.0 Omnipath 12123582 18022353
EP300 H3C2 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 7.0 1.0 Omnipath 21875947 19270680 19158375 20587414
MDC1 TP53BP1 â—¼   DOWN_REGULATES ✅ - 13.0 1.0 ACSN 12607003 15279786 15459660 17303408 17660363 18001824 18006705 18087291 18583988 18590585 18678890 7575488 9407949
MDC1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 16009723 17145710 18087291 17925396 12607005
MTOR RPTOR â—¼   PHYSICAL_INTERACTION 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
MTOR RPTOR â—¼   SHARES_COMPLEX 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
MTOR RPTOR â—¼   ENZYMATIC_REACTION ✅ 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
MTOR RPTOR â—¼   LOCALISATION ✅ 72.0 1.0 ACSN 10702316 11108711 11274345 11756498 12150925 12408816 12533512 12709531 12713446 12844354 12867079 12906785 15314020 15749884 15755954 15905173 16286006 16469695 16679021 16713974 16915281 17052453 17053147 17368478 17404308 17604271 17680028 18000759 18046414 18048642 18372248 18391071 18423201 18492954 19022819 19143636 19151919 19225151 19244117 19339977 19446321 19568798 19597330 19706736 19720745 19864431 19930715 20138985 20547845 20647036 20805416 20832730 20932932 21157483 21177869 21233202 21474067 21981924 22504639 23087689 24795729 24973821 25002027 25682865 25730849 26159692 26597054 27328425 27331412 27510662 27572739 28216025
RPTOR MTOR â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 139.0 1.0 Omnipath 15268862 24403073 20427287 22258093 21321085 19446321 15467718 19875983 17461779 12665511 12719976 16631613 21045808 21177249 23911927 24337580 25446900 24516643 18614546 12718876 12747827 16603397 17043309 18519641 22544753 25007995 27043084 19145465 23953116 19619545 16919458 24375676 15459249 16837165 16847060 25332233 12150926 22424946 26348909 12150925 18955708 20381137 22356909 17386266 17565979 18030348 16354680 20169205 19114562 21071439 27329724 35561222 16798736 15809305 22493283 17277771 15661536 16962653 1683716516603397 17604271 18676370 16183647 18505677 23297343 23872070 24036451 15066126 18570873 21614075 18722121 12408816 17599906
PDPK1 PRKCZ â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 41.0 1.0 Omnipath 12887331 14500673 11222751 18691976 10075713 20332120 9768361 9748166 17335005 10357815 16189514 11141077 16051884 11781095 10764742 14604996
PDPK1 PRKCI â—¼   POST_TRANSLATIONAL_REGULATION ✅ + 6.0 1.0 Omnipath 10764742 16189514 27554858
PLK1 TP53BP1 â—¼   POST_TRANSLATIONAL_REGULATION ✅ - 5.0 1.0 Omnipath 20126263 25607646 24703952
MDC1 MDC1 â—¼   KO_DOWN_REGULATES ✅ - -3.38 3.37 PKG 28854368
TP53BP1 TP53BP1 â—¼   KO_DOWN_REGULATES ✅ - -9.54 9.53 PKG 28854368