TP53
|
DUT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19015155
12096336
|
E2F1
|
CTNNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
14706452
18794899
|
E2F1
|
MAPK8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20800677
|
E2F1
|
MAPK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18396012
|
E2F1
|
DNMT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18319725
15867357
|
ESR1
|
MAPK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23250869
22430216
|
AR
|
MAPK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14619959
20610535
|
MYOD1
|
MAPK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10805738
9988769
|
MAPK1
|
MAPK8
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15778365
|
MAPK14
|
RB1
|
â—¼ PHOSPHORYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
17380128
5219804
|
RB1
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
5218170
16374512
|
HIF1A
|
MDM2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
12606552
15385570
|
TP53
|
PLK3
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11447225
11551930
|
TP53
|
PLK3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21394211
16581545
|
AXIN1
|
RNF111
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16601693
5218493
|
RNF111
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
SIRT1
|
SETD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
1019619108
21245319
|
SETD7
|
DNMT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
0810362106
19282482
|
AR
|
SETD7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21273441
20610535
|
SIRT1
|
SETD7
|
â—¼ METHYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
1019619108
21245319
|
DNMT1
|
SETD7
|
â—¼ METHYLATION
|
✅
|
|
2.0
|
0.8
|
intact
|
0810362106
19282482
|
SETD7
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18784729
|
H3C2
|
SIRT1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
18485871
23897426
|
H3C2
|
SIRT1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
2.0
|
0.8
|
Reactome
|
15469825
18485871
|
ESR1
|
SIRT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21920899
23658738
|
SIRT1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
27776347
28583374
|
SIRT1
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
19270680
|
MYOD1
|
SMARCA4
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17194702
17043109
|
SMARCA4
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11950834
33476981
|
STAT3
|
RB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
15677471
23874455
|
STAT3
|
SOX2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20132009
18447642
|
STAT3
|
NNMT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17922140
|
STAT3
|
MYOD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16713569
12947115
|
STAT3
|
KLF4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17129668
|
TBP
|
TAF7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
22711989
24082143
|
AR
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
19481544
7103716
|
TP53
|
H3C2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16980608
|
TP53
|
CHKA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
9501176
10094833
|
TP53
|
CAT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15059885
18487368
|
TP53
|
DLST
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17916908
21191025
|
TP53
|
PRNP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
24339999
19064990
|
TP53
|
HPSE
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
16474844
16901744
|
TP53
|
STEAP3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
19302216
|
TP53
|
DNMT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
KLF4
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10749849
16713569
|
TP53
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
10766163
16713569
|
TP53
|
RB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
STEAP3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18431400
|
TP53
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
7915517
|
PGK1
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
7995081
20849852
|
SMURF2
|
ATP5F1B
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18157088
6492033
|
GABARAP
|
GPHN
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
25882190
10900017
|
SMAD7
|
MYOD1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
CTNNB1
|
MYOD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
18948405
15031118
|
RB1
|
MYOD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
21902831
8381715
|
SMURF2
|
SMAD7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
15231748
5217094
|
SMAD7
|
CTNNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15684397
1568439
|
AXIN1
|
SMAD7
|
â—¼ COLOCALIZATION
|
|
|
2.0
|
0.8
|
intact
|
16601693
5218493
|
SMURF2
|
NDUFA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
18157088
6492033
|
COX5A
|
COX4I2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
ACSN
|
17418790
8194600
|
COX5A
|
COX4I2
|
â—¼ SHARES_COMPLEX
|
|
|
2.0
|
0.8
|
ACSN
|
17418790
8194600
|
HIF1A
|
ENO2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
19828020
|
SMURF2
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
23331499
16950122
|
AR
|
INSR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20610535
20417685
|
ESR1
|
CTNNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
16628468
|
CTNNB1
|
ENPP2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15592430
15642117
|
CTNNB1
|
GAD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
15592430
12782598
|
CTNNB1
|
SOX2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
24291232
24482235
|
DNMT1
|
CYP1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17682057
15820101
|
ESR1
|
HSD3B1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
20410197
18511507
|
AR
|
LCT
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
8576035
20610535
|
PLCB2
|
PLCB4
|
â—¼ PHOSPHOLIPASE
|
✅
|
|
2.0
|
0.8
|
Reactome
|
11015615
2841328
|
TBP
|
MAPK8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
17074809
19620725
|
RB1
|
TBP
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
2.0
|
0.8
|
Omnipath
|
11094070
16713569
|
HSD3B1
|
DLST
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
PSAT1
|
DLST
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
108050
32814053
|
H3C2
|
MBD2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
Reactome
|
14610093
10471499
|
NR2F2
|
PCK2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
2.0
|
0.8
|
Omnipath
|
14739255
11399762
|
H3C2
|
L3MBTL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16415788
5218238
|
NME7
|
NT5C2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
2.0
|
0.8
|
intact
|
16189514
5217968
|
H3F3A
|
UHRF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
813.0
|
0.81
|
STRING
|
36370105
|
HIST1H4A
|
L3MBTL1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
813.0
|
0.81
|
STRING
|
36370105
|
ESR1
|
KLF4
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
23403292
31527615
|
ESR1
|
CERS2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
19805454
31527615
|
LPIN3
|
LPIN2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
PDE1C
|
PDE1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.82
|
0.82
|
HIPPIE
|
28514442
33961781
|
COX5A
|
NDUFA1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
COX5A
|
NDUFA7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
COX5A
|
NDUFB7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
HIST1H4A
|
SOX2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
823.0
|
0.82
|
STRING
|
36370105
|
TAF10
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
7923369
31527615
|
PCNA
|
UHRF1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
30357346
26496610
|
ENPP6
|
ALG9
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
28514442
33961781
26186194
|
NR1H4
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
17333335
25675114
|
ESR1
|
MBD2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.83
|
0.83
|
HIPPIE
|
20300195
31527615
|
HIST1H4A
|
SMARCA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
831.0
|
0.83
|
STRING
|
36370105
|
ESR1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
835.0
|
0.83
|
STRING
|
36370105
|
MAPK14
|
RB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
839.0
|
0.84
|
STRING
|
36370105
|
SMARCA4
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
HIF1A
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
840.0
|
0.84
|
STRING
|
36370105
|
HIST1H4A
|
HIST3H3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
H3F3A
|
HIST1H4A
|
â—¼ PHYSICAL_INTERACTION
|
|
|
843.0
|
0.84
|
STRING
|
36370105
|
H3F3A
|
SMARCA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
845.0
|
0.84
|
STRING
|
36370105
|
SETD7
|
TAF7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
15099517
16415881
|
STAT3
|
HIF1A
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.85
|
0.85
|
HIPPIE
|
15735682
18985005
23604114
23991099
|
H3F3A
|
HIST3H3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
851.0
|
0.85
|
STRING
|
36370105
|
ESR1
|
STAT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
23874500
11429412
|
YAP1
|
AXIN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
24976009
29789528
|
SMAD7
|
AXIN1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.86
|
0.86
|
HIPPIE
|
16601693
18593713
|
TBP
|
MDM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
9388200
16713569
9271120
|
PGK1
|
PCNA
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.87
|
0.87
|
HIPPIE
|
26030842
20849852
|
HIF1A
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
870.0
|
0.87
|
STRING
|
36370105
|
MAPK1
|
MAPK14
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
HIF1A
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
874.0
|
0.87
|
STRING
|
36370105
|
SMURF2
|
SMAD7
|
â—¼ UBIQUITINATION
|
✅
|
-
|
0.87
|
0.87
|
Signor
|
18448069
|
SMAD7
|
SMURF2
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.87
|
0.87
|
Signor
|
19352540
|
RB1
|
SMARCA4
|
â—¼ PHYSICAL_INTERACTION
|
|
|
875.0
|
0.87
|
STRING
|
36370105
|
MAPK1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
876.0
|
0.87
|
STRING
|
36370105
|
MAPK14
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
MYOD1
|
STAT3
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
12947115
16713569
|
YAP1
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.88
|
0.88
|
mint
|
22234184
8383887
|
SMURF1
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
879.0
|
0.88
|
STRING
|
36370105
|
MBD2
|
DNMT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.88
|
0.88
|
HIPPIE
|
10947852
27593931
|
TBP
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
880.0
|
0.88
|
STRING
|
36370105
|
MDM2
|
RB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
881.0
|
0.88
|
STRING
|
36370105
|
MAPK8
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
884.0
|
0.88
|
STRING
|
36370105
|
SIRT1
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
885.0
|
0.88
|
STRING
|
36370105
|
SETD7
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
886.0
|
0.88
|
STRING
|
36370105
|
MAPK1
|
STAT3
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
MDM2
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
12897156
11178989
16713569
10766163
17545634
31012223
|
DNMT1
|
SETD7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
21151116
19282482
|
SETD7
|
TAF10
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
15099517
16415881
|
TAF10
|
TAF7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
29111974
22939629
15099517
17643375
9603525
23292512
14580349
|
CTNNB1
|
YAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
889.0
|
0.89
|
STRING
|
36370105
|
PCNA
|
DNMT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
20940144
20613874
24958773
9302295
26496610
30301766
12354094
23708667
22606318
10888872
|
CTNNB1
|
AR
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.89
|
0.89
|
mint
|
5216126
12588987
|
TBP
|
ESR1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.89
|
0.89
|
HIPPIE
|
9259327
16713569
31527615
11595744
|
SMURF1
|
SMAD7
|
â—¼ UBIQUITINATION
|
✅
|
-
|
0.89
|
0.89
|
Signor
|
12519765
|
SMAD7
|
SMURF1
|
â—¼ RELOCALIZATION
|
✅
|
+
|
0.89
|
0.89
|
Signor
|
19352540
|
E2F1
|
MDM2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
10914734
20837136
|
E2F1
|
DNMT1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
24502362
17575144
15867357
|
TP53
|
MAPK14
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
11437382
15132979
14570892
|
AR
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
HIF1A
|
MDM2
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
12606552
10640274
25447306
15880652
19696166
25535359
17234751
15385570
|
STAT3
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
21546410
|
STAT3
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
16107692
23874455
20043094
|
STAT3
|
CTNNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20830236
|
TBP
|
TAF10
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
16945932
18722179
12020826
|
TBP
|
TAF7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
29111974
17158164
19240132
9603525
22323595
9153318
12665565
9311784
|
TP53
|
SERTAD1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
15843459
|
YAP1
|
SMAD7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
25283809
22921829
12118366
|
YAP1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
23607968
22234184
23245941
|
H3C2
|
UHRF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
3.0
|
0.9
|
Reactome
|
22064703
17673620
22348533
|
UHRF1
|
DNMT1
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.9
|
0.9
|
HIPPIE
|
20613874
22064703
19798101
33170271
17673620
29691401
19800870
21045206
29268763
33465813
21268065
21745816
24782312
27045799
19943104
17934516
28803780
31322780
27049577
26065575
24368767
|
NR2F2
|
MYOD1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
9826778
|
AXIN1
|
SMAD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
3.0
|
0.9
|
Omnipath
|
16601693
|
HIF1A
|
GYS1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
19828020
|
AR
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
899.0
|
0.9
|
STRING
|
36370105
|
AR
|
TBP
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20610535
9238003
|
AR
|
ALDH1A3
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
20610535
17526768
|
TBP
|
RB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
3.0
|
0.9
|
Omnipath
|
9242374
10197586
9400991
|
TAF6
|
TAF7
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.92
|
0.92
|
HIPPIE
|
14580349
29111974
22939629
|
CTNNB1
|
AXIN1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.94
|
0.94
|
mint
|
5219694
17318191
|
ESR1
|
NR2F2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
940.0
|
0.94
|
STRING
|
36370105
|
TAF10
|
TAF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.95
|
0.95
|
HIPPIE
|
22939629
17375202
15099517
19114550
9603525
23292512
12601814
14580349
26344197
|
COX5A
|
NDUFAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
COX5A
|
NDUFA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
956.0
|
0.95
|
STRING
|
36370105
|
TAF10
|
TBP
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.96
|
0.96
|
HIPPIE
|
7923369
17375202
15099517
19240132
7744009
7680771
9603525
10373431
9674425
9153318
22323595
23292512
22939629
17967894
|
SMAD7
|
YAP1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
COX5A
|
NDUFA12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
960.0
|
0.96
|
STRING
|
36370105
|
RB1
|
E2F1
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.97
|
0.97
|
mint
|
5219804
17380128
|
SMAD7
|
SMURF2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
971.0
|
0.97
|
STRING
|
36370105
|
HIST3H3
|
UHRF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
975.0
|
0.97
|
STRING
|
36370105
|
DNMT1
|
PCNA
|
â—¼ PHYSICAL_INTERACTION
|
|
|
976.0
|
0.97
|
STRING
|
36370105
|
DNMT1
|
RB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
980.0
|
0.98
|
STRING
|
36370105
|
SMAD7
|
SMURF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
983.0
|
0.98
|
STRING
|
36370105
|
NDUFA12
|
NDUFA7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
987.0
|
0.98
|
STRING
|
36370105
|
TP53
|
MDM2
|
â—¼ PHYSICAL_INTERACTION
|
✅
|
|
0.99
|
0.99
|
mint
|
17139261
5219401
|
TBP
|
TAF6
|
â—¼ PROTEIN_INTERACTION
|
|
|
0.99
|
0.99
|
HIPPIE
|
17375202
8858156
15870280
19240132
7680771
9603525
22323595
9674425
9153318
12453419
22939629
17967894
12665565
9311784
|
TAF6
|
TBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
DNMT1
|
UHRF1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
AXIN1
|
CTNNB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
995.0
|
0.99
|
STRING
|
36370105
|
MDM2
|
TP53
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
NDUFA12
|
NDUFA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
998.0
|
0.99
|
STRING
|
36370105
|
E2F1
|
RB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
18.0
|
1.0
|
ACSN
|
11877377
15175241
15279786
15459660
16581787
17218262
17303408
17660363
17713585
18458534
18590585
19793801
20029420
21060331
21337561
24254977
7575488
7935440
|
E2F1
|
RB1
|
â—¼ PROTEIN_INTERACTION
|
|
|
18.0
|
1.0
|
ACSN
|
11877377
15175241
15279786
15459660
16581787
17218262
17303408
17660363
17713585
18458534
18590585
19793801
20029420
21060331
21337561
24254977
7575488
7935440
|
E2F1
|
RB1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
18.0
|
1.0
|
ACSN
|
11877377
15175241
15279786
15459660
16581787
17218262
17303408
17660363
17713585
18458534
18590585
19793801
20029420
21060331
21337561
24254977
7575488
7935440
|
TP53
|
E2F1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
21715977
20805247
8557038
11795482
17210690
22952705
|
ESR1
|
E2F1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
22791811
20215421
12697671
10446910
|
E2F1
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
7623816
12782299
14618416
20580656
9389735
11133765
8903355
9649317
23078099
12468739
1261188
|
E2F1
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
21966451
17178887
22508987
21099110
21099103
|
E2F1
|
UHRF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
24453336
12838312
15361834
23023523
|
E2F1
|
RB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
17.0
|
1.0
|
Omnipath
|
11533237
16081466
16738312
16188218
15618023
14681231
16230367
15985428
8264596
18583990
16601104
14627987
15016799
11268000
10490838
11818069
|
E2F1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
22241525
8557038
15706352
21441950
12675512
23954287
12625370
|
RB1
|
E2F1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
90.0
|
1.0
|
Omnipath
|
17145710
23472054
12502741
22078878
8896460
12397079
9315635
20839231
16249186
11839806
8255752
11713253
20871633
15837424
8346196
19249677
16360038
8626527
12096339
15485814
16374512
18391203
9125176
16766265
9468140
8816798
12598654
10393912
9400991
9632788
12947005
19477924
15485920
17380128
10523633
10869426
7828850
18216119
8657117
12963846
25257171
17488475
28074012
15670817
11583618
7739537
10499802
8413249
11090181
8230483
22768064
29521627
10207050
9553123
7958924
11420730
23001041
16496386
9501179
19058874
1388726
9422723
|
E2F1
|
PCNA
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
15510213
18319725
11491305
|
E2F1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
22480684
11739724
12625370
|
MAPK14
|
MAPK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
15187187
21675959
18039929
12738796
11157753
22521293
17255949
11238443
11274345
12697810
|
MAPK1
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
59.0
|
1.0
|
Omnipath
|
18448488
19413330
11335711
9343414
15465816
25584415
12576423
11350938
20068231
12681450
12763138
9872331
11780390
18491316
18669648
11404481
10521505
18691976
20058876
15979846
14551213
10446219
|
MAPK1
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
16954218
10551817
18519666
18687685
26784107
|
MAPK1
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
30.0
|
1.0
|
Omnipath
|
15655247
10949034
15528270
18372406
15461668
12118371
12466266
7495695
17615152
15059947
16076840
7491495
12093745
10409727
9528769
7838153
|
MAPK1
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
18511414
9725910
10318905
|
MAPK1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
29.0
|
1.0
|
Omnipath
|
14965474
9765199
15116093
21675959
23443559
10781582
25241761
10446957
10958792
11409876
11709713
21147777
10673501
11551930
15867353
11875057
12091386
|
MAPK1
|
PDE4D
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
12.0
|
1.0
|
Omnipath
|
16973330
9915826
10828059
10022832
|
MAPK14
|
PIP4K2B
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
5.0
|
1.0
|
Omnipath
|
16949365
|
MAPK14
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
57.0
|
1.0
|
Omnipath
|
21675959
26247731
20213747
17535811
20506250
15657900
9315650
15642743
19413330
11283254
22975381
10581258
16083285
1088347
21614932
16393692
10884347
21050851
16552184
10747897
15187187
17906639
25789565
15140942
11258706
24818748
19436832
10781582
10212189
17172861
10348343
11078726
11274345
|
MAPK14
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
23331499
10201984
18691976
17502367
17570479
|
MAPK14
|
RB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
20.0
|
1.0
|
Omnipath
|
11439341
17599043
9190208
15355984
17380128
22279936
27642049
33419772
1756735
17996702
17570479
22895174
20871633
20223825
33219128
|
MAPK14
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
13.0
|
1.0
|
Omnipath
|
23216744
22431515
12138194
15879307
|
MAPK14
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20626350
11278789
|
MAPK14
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
30644418
24424504
21820033
16282370
|
TP53
|
MDM2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
201.0
|
1.0
|
Omnipath
|
23150757
20948295
10871862
10914734
21422812
21957016
14532965
22290440
20663877
20547751
11591713
24339722
11840331
22223137
16492744
15843377
22948151
7888679
20156675
21217645
22180176
8319905
9707425
15831521
17690113
9649502
10688649
9194564
15917661
15090541
20837136
8187772
10788589
17907153
15192123
8440237
11964305
16510138
10856296
15580300
7624148
12208736
21211512
16624812
17848574
11245471
21637567
20588255
10562557
9525742
9270029
16479015
19941079
14602726
15024021
18814047
20036872
10718212
18852133
12374749
18397889
25016801
12755686
22081073
22245141
23365201
8957072
22197810
15856024
20703075
23483203
9645455
19648117
20331637
22301280
14743206
23982177
9486848
15734740
19638633
19671680
17310983
10469568
20659896
10072445
21097889
17237821
11748232
11085543
21750655
16337599
21295542
1614537
9815889
9070662
16585169
9472631
17936559
17139261
11328884
12887889
20858413
9858609
14610316
20080970
19505873
11313463
15684615
18359851
18783169
16202543
9267820
12235242
14990790
15851483
7587074
18336191
21478269
17043642
15361831
18025460
23612020
10208414
11756653
24389645
9071998
9430645
9400998
9371494
23149414
22532570
9271120
10777217
22383580
18781178
12606552
14514686
17318220
11127813
16571800
19085961
9207798
10891494
10065155
11593391
14570892
12902982
19649205
20124454
17390010
19955655
12138177
19663772
23581014
15908423
10321740
23150759
19837670
10348346
18632610
9294611
11956627
12750288
12851404
8313378
9135153
15735665
7958853
8247544
9535786
16501602
18566224
8910340
11046142
9405685
7936649
12173040
17329361
21451571
14704432
23874713
18333294
19541936
22787160
18585004
22085928
12080472
7651818
11179471
10949923
19428175
15592502
8413278
11714701
10566557
18583933
9681831
15550242
15007388
19590512
|
ESR1
|
MDM2
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
12897156
17166846
12750288
8324731
22787161
21169420
19578757
|
MDM2
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
559.0
|
1.0
|
Omnipath
|
20657550
30005830
17616658
9529249
10321734
33650658
9724739
24462112
24621507
15933712
23826318
24667498
22948151
22653443
23776060
25313037
25241761
19303885
16857591
23246961
19033382
20591651
21149449
25417702
15122315
16579792
27543608
29670376
12208736
17848574
26673821
25277184
23443559
23318437
21060154
15210108
19805293
8875929
8058315
21471462
17879958
25362358
23169665
22301280
21584881
20124408
10980696
26876197
17310983
17380154
15058298
24567357
18665269
30109812
25637791
18467333
22337874
22227409
22389628
15242646
22510990
15950904
15001357
19483087
26540344
14559824
21986495
26556313
20708156
19901969
33765973
32528731
11562347
10202144
22374672
10722742
22083959
21965653
17098746
19234109
30679555
16107876
12690203
22525275
19071110
28542145
12620407
20837658
27129163
9131587
24240685
27031960
10681559
19305137
11744695
19188367
16023600
24659749
17347673
12944468
20395212
22084066
20639885
21454483
12897156
16432196
10347217
10706102
11178989
20174603
16751805
15542844
12842086
11431470
11384992
25739118
15064742
23402884
27462439
16905769
22124327
27215386
12867035
22588298
27336364
14702041
16152627
23776465
22262183
21132010
19411846
18309296
23483203
11709713
18981217
14612427
22920093
23671280
24980433
27905468
25168242
21750659
26238070
22737255
23609977
27282385
20847049
20705607
21075307
28082682
17297477
11697899
17936559
24361594
19098711
15469934
34591612
24998844
16212962
11094089
12915590
17116689
11713288
15144954
23201157
10608892
17591690
25156994
17301054
22444248
26883110
26001071
19160491
22157679
24413661
19357310
23802716
15280377
21317885
11597128
19579266
25624478
18061646
21088494
9223638
10435614
31177307
11331603
22391559
20570896
19941302
9278461
18485870
15604276
18566590
12612087
11046142
14704432
26186194
10935507
16173922
14596917
17159902
25543083
19656744
15848166
18316739
22266868
17056014
19255450
21561866
19590512
11839577
22991965
22266850
24200963
11285227
11713287
22975381
19081178
20660730
26475964
16678796
23261415
20173098
17666403
25464845
32427887
23252402
17438265
20959462
22659184
17470788
22912717
17080083
15247280
19332559
17989425
16870621
18813780
20235143
11278372
10562557
25609649
10561590
19411066
17908790
19568783
7926727
21925390
21988832
24127580
18604177
14499615
17371838
17525743
33061576
21887275
26578655
21084564
16861890
20694676
12552135
22914926
17363365
24643130
1614537
22916255
12381304
34992144
12167711
19857530
15053879
10889512
11486026
22103682
16713569
17110336
17426254
10640350
21316347
21478269
15154850
12529318
16595680
16414131
19597489
23880345
27893708
7686617
27811966
17318220
29997244
27308622
19166840
35044719
16159876
24314634
15313915
25283148
22032989
24926618
18172499
19837670
16215989
23134341
26908445
9824166
18451149
21170087
23572512
21465263
22807444
15013777
16845383
10488081
23946421
11714701
25384516
22474335
25312347
23370271
23150757
18541670
22318540
11925449
21572037
24488098
32066565
17268548
20542919
11572869
16338390
21857681
23150668
19223463
20234175
20484049
11070080
20591429
22575647
11351297
16624812
22411991
20588255
17369817
11223036
15908921
9582019
25103245
17302414
21071676
9450543
31968249
34562520
18332869
14671306
21084285
27856536
30464405
26882543
21726810
33020477
21261729
21268072
12426395
16964247
20659896
19106616
22331460
23728348
10827196
22524527
21098709
9363941
17139261
20080206
14517261
22487680
31652301
17290220
27106262
16866370
24207125
28223335
9271120
15550400
7689721
26350565
10196247
27807478
10766163
15558054
35371302
26203195
29487367
25512388
25954860
18223694
15824742
24842904
14741215
16055726
22085928
32894144
18234963
17875722
18815136
15295102
15308643
15358376
22819825
15094782
|
MDM2
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
15880652
25535359
12606552
25447306
17234751
19696166
10640274
|
MDM2
|
RB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
16374512
21990374
7791904
28615518
33185004
20871633
10078201
|
MDM2
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
11.0
|
1.0
|
Omnipath
|
17974989
26411689
27835608
26973243
15640443
12145204
|
PLK3
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
33.0
|
1.0
|
Omnipath
|
15489221
24395704
11709713
10801407
15254178
16581545
12242661
16713569
12111733
11551930
19607708
10673501
11875057
11447225
12548019
|
PLK3
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
18519666
20889502
26784107
|
AXIN1
|
RNF111
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
16601693
23331499
14657019
|
RNF111
|
SMAD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
9.0
|
1.0
|
Omnipath
|
23331499
14657019
|
SETD7
|
TAF10
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
8.0
|
1.0
|
Omnipath
|
15099517
16415881
|
SETD7
|
H3C2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
11779497
15525938
12540855
16415881
22403242
18022353
|
SETD7
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
21988832
17805299
15525938
16415881
17108971
21245319
|
MAPK8
|
SIRT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
20.0
|
1.0
|
Omnipath
|
29578371
17081983
19007248
23434668
21540183
22622703
17924679
18187866
24296261
18838864
19413330
20027304
21471201
19107194
16964243
18669648
15302935
|
SIRT1
|
SMAD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
21071413
23331499
17098745
|
SIRT1
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
21.0
|
1.0
|
Omnipath
|
18235502
11672523
18235501
15205477
35931247
15989956
17964266
25280219
19047049
16713569
19960022
21245319
12006491
19590512
|
SMARCA4
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
9099865
18451880
11003650
|
SMARCA4
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
11532957
14964309
|
STAT3
|
HIF1A
|
â—¼ DOWN_REGULATES
|
✅
|
-
|
24.0
|
1.0
|
ACSN
|
10347215
10973499
12223527
14607900
14670306
15218058
15356132
15573129
16418395
18776941
18985005
19380816
20093776
20237412
20406969
20581311
21840487
23124025
23454751
23953057
24857661
27216177
28186502
7543512
|
STAT3
|
HIF1A
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
19265129
18644974
16007214
20924113
17597020
23991099
|
MAPK8
|
STAT3
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
66.0
|
1.0
|
Omnipath
|
23255093
17502367
21702955
19413330
11335711
9343414
23331499
15465816
12576423
11350938
20068231
12763138
9872331
18491316
18669648
10521505
18691976
20058876
15979846
14551213
10446219
|
STAT3
|
DNMT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15870198
16861352
25854163
|
STAT3
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
15735682
18985005
10973499
|
TAF10
|
TBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
TAF10
|
TAF6
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
TAF10
|
TAF7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
TAF6
|
TAF7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
TAF7
|
TBP
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
ESR1
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
20080630
16115928
22787161
12750288
20696891
17681750
17699779
|
KLF4
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
18511453
16244670
17308127
21132436
17659301
|
HIF1A
|
TP53
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
12542982
17390008
9537326
15780936
11696352
10469629
17236590
20706634
15629713
11007955
|
TP53
|
CTNNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
10.0
|
1.0
|
Omnipath
|
11564862
20697347
20729811
21691299
19411072
24473123
20064927
18245266
18758483
18372914
|
TP53
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
6.0
|
1.0
|
Omnipath
|
17202838
18084622
18945670
11504717
|
TP53
|
UHRF1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
4.0
|
1.0
|
Omnipath
|
23677994
19501055
18220474
21382456
|
TP53
|
PCNA
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
26.0
|
1.0
|
Omnipath
|
10321841
7915517
15358233
12217864
10516009
1705714
8570655
16980608
9707425
15950182
19789303
11313928
1356162
12384701
9858527
12947108
23390122
8524244
9651310
1352831
7909518
11032828
10910968
12485898
10618724
|
TP53
|
RB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
23.0
|
1.0
|
Omnipath
|
11850820
10029406
16931621
9774636
8845569
8270002
11244564
15618023
12444079
12749855
21496227
11818069
15827088
8720930
1608930
8119988
23474762
11121443
22729911
22894933
8355507
|
TP53
|
MAPK8
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
22607268
23376463
18374905
15958553
10854211
22353755
|
MAPK8
|
TP53
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
37.0
|
1.0
|
Omnipath
|
11108663
12531896
16713569
11283254
10706102
19651615
27147566
9724739
15538975
9732264
10581258
10436023
17570479
9393873
11896587
12514174
15580310
18813780
11078726
|
TP53
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
-
|
7.0
|
1.0
|
Omnipath
|
9537326
16713569
12124396
15629713
16882692
|
YAP1
|
SMAD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
12.0
|
1.0
|
Omnipath
|
23331499
22921829
12118366
25283809
|
PCNA
|
DNMT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
11.0
|
1.0
|
Omnipath
|
17991895
18384127
31235252
28073635
12354094
9302295
|
UHRF1
|
DNMT1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
23.0
|
1.0
|
Omnipath
|
19798101
22064703
20210320
17673620
24368767
19800870
27049577
20613874
21268065
24782312
26065575
17934516
21045206
21745816
19308066
27045799
|
NDUFA2
|
NDUFAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA7
|
NDUFAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA12
|
NDUFAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFAB1
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFAB1
|
NDUFB7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA7
|
NDUFAB1
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA12
|
NDUFAB1
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFAB1
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA2
|
NDUFAB1
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFAB1
|
NDUFB7
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
MYOD1
|
RB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
7970718
10373569
10601020
10801445
16936743
12665587
20053773
|
PCCB
|
HLCS
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
4.0
|
1.0
|
Reactome
|
22123817
16134170
20153287
9630604
|
CTNNB1
|
SMAD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
7.0
|
1.0
|
Omnipath
|
23331499
15684397
21071413
18988627
|
SMURF1
|
SMAD7
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
40.0
|
1.0
|
Omnipath
|
22773947
12151385
23331499
22921829
21071413
18988627
11278251
12408818
12519765
22152476
27292644
20937913
15221015
24700460
14722617
16720724
23959799
|
SMAD7
|
SMURF2
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
38.0
|
1.0
|
Omnipath
|
26435193
22773947
15231748
23331499
22921829
16641086
17719543
21791611
26679521
11163210
27292644
20937913
15221015
18448069
22624557
32283253
23973329
16061177
14722617
19352540
|
AXIN1
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
52.0
|
1.0
|
Omnipath
|
20128690
20531388
16890161
27902311
22509369
18593713
16199882
23331499
9482734
21071413
26496610
19244247
22773187
17318191
10196136
18988627
17208333
19131971
24976009
22682247
10228155
12805222
12000790
10488109
9501208
9601641
18632848
9554852
19166851
23959799
12421363
9734785
11940574
|
NDUFA1
|
NDUFA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFA12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFA7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFB7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFB7
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFA12
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFA7
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA1
|
NDUFA2
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA2
|
NDUFA12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA7
|
NDUFA12
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA12
|
NDUFB7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA7
|
NDUFA12
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA2
|
NDUFA12
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA12
|
NDUFB7
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA7
|
NDUFA2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA2
|
NDUFA7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
999.0
|
1.0
|
STRING
|
36370105
|
NDUFA2
|
NDUFB7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA7
|
NDUFA2
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA2
|
NDUFB7
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA7
|
NDUFB7
|
â—¼ PHYSICAL_INTERACTION
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
NDUFA7
|
NDUFB7
|
â—¼ SHARES_COMPLEX
|
|
|
10.0
|
1.0
|
ACSN
|
15186778
15526035
15807660
16200211
16218961
17344420
18485875
19131594
20025615
20816094
|
HIF1A
|
COX4I2
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
66.0
|
1.0
|
ACSN
|
10102273
10428030
10428780
10435632
10804084
10823814
11557773
11559532
11744734
11756417
11884613
12402042
12676992
12743597
14672622
14684737
14699081
14762718
15024076
15059920
15199147
15240700
15312748
15369676
15379897
15545625
16110315
16126909
16127144
16517405
16517406
16585195
16782875
16888645
17143338
17418790
17533374
17785433
18054315
18056423
18158893
18718909
19211554
20028863
20427344
20535745
20855962
21051947
21765015
22006996
22841746
22850421
22988108
24006507
25043024
25103413
25732824
7493931
7500013
7508926
8089148
8702901
8955077
9486205
9525945
9707622
|
HIF1A
|
PGK1
|
â—¼ ENZYMATIC_REACTION
|
✅
|
|
66.0
|
1.0
|
ACSN
|
10102273
10428030
10428780
10435632
10804084
10823814
11557773
11559532
11744734
11756417
11884613
12402042
12676992
12743597
14672622
14684737
14699081
14762718
15024076
15059920
15199147
15240700
15312748
15369676
15379897
15545625
16110315
16126909
16127144
16517405
16517406
16585195
16782875
16888645
17143338
17418790
17533374
17785433
18054315
18056423
18158893
18718909
19211554
20028863
20427344
20535745
20855962
21051947
21765015
22006996
22841746
22850421
22988108
24006507
25043024
25103413
25732824
7493931
7500013
7508926
8089148
8702901
8955077
9486205
9525945
9707622
|
HIF1A
|
PGK1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
6.0
|
1.0
|
Omnipath
|
15794924
19828020
8089148
18024476
|
RB1
|
HIF1A
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
15674338
|
HIF1A
|
PGK1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
16585195
8089148
8702901
|
AR
|
CTNNB1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
5.0
|
1.0
|
Omnipath
|
18535113
18673534
20610535
11916967
|
AR
|
CTNNB1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
41.0
|
1.0
|
Omnipath
|
21741601
16713569
12799378
12944908
10809237
23331499
15060161
21071413
21885566
18988627
16428447
11916967
12588987
11792709
10987273
14593076
15256534
22187462
|
DNMT1
|
H3C2
|
â—¼ PHYSICAL_INTERACTION
|
|
|
5.0
|
1.0
|
Reactome
|
16357870
24074865
23326524
12435631
22466170
|
DNMT1
|
ESR1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
10.0
|
1.0
|
Omnipath
|
21655924
20946668
17172825
15746193
22975348
12789259
19001520
24058781
23242655
22558281
|
ESR1
|
CYP1A1
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
-
|
8.0
|
1.0
|
Omnipath
|
16972788
16010691
17511620
15858227
15837795
20716622
22837390
|
ESR1
|
AR
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
8299561
11000528
22391641
|
AR
|
ESR1
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
9.0
|
1.0
|
Omnipath
|
23331499
12389206
11032808
16713569
11000528
18988627
|
AR
|
NME7
|
â—¼ TRANSCRIPTIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
20610535
|
MAPK8
|
AR
|
â—¼ POST_TRANSLATIONAL_REGULATION
|
✅
|
+
|
4.0
|
1.0
|
Omnipath
|
24424504
21512132
21820033
16282370
|